MCL coexpression mm9:1936

Phase1 CAGE Peaks

	Short description
Mm9::chr11:101036754..101036758,-	p1@Ccr10
Mm9::chr12:114498239..114498250,-	p@chr12:114498239..114498250 -
Mm9::chr12:114498257..114498273,-	p@chr12:114498257..114498273 -
Mm9::chr12:114864234..114864248,-	p1@ENSMUST00000103446

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016494	C-X-C chemokine receptor activity	0.00547855147099107
GO:0019958	C-X-C chemokine binding	0.00547855147099107
GO:0016493	C-C chemokine receptor activity	0.00547855147099107
GO:0019957	C-C chemokine binding	0.00547855147099107
GO:0001637	G-protein chemoattractant receptor activity	0.00547855147099107
GO:0004950	chemokine receptor activity	0.00547855147099107
GO:0019956	chemokine binding	0.00547855147099107
GO:0019955	cytokine binding	0.0128472031994741
GO:0001653	peptide receptor activity	0.0156467430011505
GO:0008528	peptide receptor activity, G-protein coupled	0.0156467430011505
GO:0042277	peptide binding	0.0181290248676432

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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