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MCL coexpression mm9:2002

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:8473449..8473455,-p@chr11:8473449..8473455
-
Mm9::chr6:142227366..142227375,-p8@Slco1a5
Mm9::chr6:23789471..23789487,-p6@Cadps2
Mm9::chr7:126750528..126750543,+p3@Acsm1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0003996acyl-CoA ligase activity0.0170930805894921
GO:0047760butyrate-CoA ligase activity0.0273384412419082
GO:0045921positive regulation of exocytosis0.0273384412419082
GO:0016405CoA-ligase activity0.0273384412419082
GO:0015125bile acid transmembrane transporter activity0.0273384412419082
GO:0042734presynaptic membrane0.0277579977885324
GO:0016878acid-thiol ligase activity0.0277579977885324
GO:0015645fatty-acid ligase activity0.0277579977885324
GO:0008028monocarboxylic acid transmembrane transporter activity0.0303627317573212
GO:0017157regulation of exocytosis0.0307388963968232
GO:0016877ligase activity, forming carbon-sulfur bonds0.0356970149106896
GO:0051050positive regulation of transport0.0469236058830785



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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