MCL coexpression mm9:2002

Phase1 CAGE Peaks

	Short description
Mm9::chr11:8473449..8473455,-	p@chr11:8473449..8473455 -
Mm9::chr6:142227366..142227375,-	p8@Slco1a5
Mm9::chr6:23789471..23789487,-	p6@Cadps2
Mm9::chr7:126750528..126750543,+	p3@Acsm1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0003996	acyl-CoA ligase activity	0.0170930805894921
GO:0047760	butyrate-CoA ligase activity	0.0273384412419082
GO:0045921	positive regulation of exocytosis	0.0273384412419082
GO:0016405	CoA-ligase activity	0.0273384412419082
GO:0015125	bile acid transmembrane transporter activity	0.0273384412419082
GO:0042734	presynaptic membrane	0.0277579977885324
GO:0016878	acid-thiol ligase activity	0.0277579977885324
GO:0015645	fatty-acid ligase activity	0.0277579977885324
GO:0008028	monocarboxylic acid transmembrane transporter activity	0.0303627317573212
GO:0017157	regulation of exocytosis	0.0307388963968232
GO:0016877	ligase activity, forming carbon-sulfur bonds	0.0356970149106896
GO:0051050	positive regulation of transport	0.0469236058830785

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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