MCL coexpression mm9:2074

Phase1 CAGE Peaks

	Short description
Mm9::chr13:51740637..51740645,+	p3@Cks2 p3@Gm19945 p3@LOC100044750 p3@LOC100046104
Mm9::chr13:51740653..51740668,+	p2@Cks2 p2@Gm19945 p2@LOC100044750 p2@LOC100046104
Mm9::chr2:53051135..53051162,+	p1@Arl6ip6
Mm9::chr7:138703877..138703912,+	p1@Bub3

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0000279	M phase	0.0139238266613713
GO:0022403	cell cycle phase	0.0139238266613713
GO:0022402	cell cycle process	0.0211683242715775
GO:0000070	mitotic sister chromatid segregation	0.0211683242715775
GO:0000819	sister chromatid segregation	0.0211683242715775
GO:0016538	cyclin-dependent protein kinase regulator activity	0.0211683242715775
GO:0000910	cytokinesis	0.0211683242715775
GO:0007049	cell cycle	0.0211683242715775
GO:0007127	meiosis I	0.0211683242715775
GO:0004693	cyclin-dependent protein kinase activity	0.0211683242715775
GO:0007059	chromosome segregation	0.0294814878721136
GO:0019887	protein kinase regulator activity	0.032555848320863
GO:0051327	M phase of meiotic cell cycle	0.032555848320863
GO:0007126	meiosis	0.032555848320863
GO:0019207	kinase regulator activity	0.032555848320863
GO:0051321	meiotic cell cycle	0.032555848320863

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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