MCL coexpression mm9:2424

Phase1 CAGE Peaks

	Short description
Mm9::chr5:33088966..33088990,-	p3@Pisd
Mm9::chr7:133903127..133903165,+	p1@Mapk3
Mm9::chr7:134158099..134158119,-	p2@Mvp
Mm9::chr7:52317763..52317806,-	p1@Prrg2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0004609	phosphatidylserine decarboxylase activity	0.0328875546140376
GO:0001784	phosphotyrosine binding	0.0328875546140376
GO:0045309	protein phosphorylated amino acid binding	0.0328875546140376
GO:0043330	response to exogenous dsRNA	0.0328875546140376
GO:0031663	lipopolysaccharide-mediated signaling pathway	0.0328875546140376
GO:0032496	response to lipopolysaccharide	0.0328875546140376
GO:0051219	phosphoprotein binding	0.0328875546140376
GO:0004707	MAP kinase activity	0.0328875546140376
GO:0043331	response to dsRNA	0.0328875546140376
GO:0002237	response to molecule of bacterial origin	0.0386933980653405
GO:0019233	sensory perception of pain	0.049278644848648
GO:0016831	carboxy-lyase activity	0.049278644848648

Relative expression of the co-expression cluster over median <br>Analyst:

---

"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

---

Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}