MCL coexpression mm9:2722

Phase1 CAGE Peaks

	Short description
Mm9::chr11:81849071..81849087,+	p1@Ccl2
Mm9::chr11:81849690..81849692,+	p@chr11:81849690..81849692 +
Mm9::chr16:57754820..57754837,-	p1@Col8a1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0048593	camera-type eye morphogenesis	0.03797229016055
GO:0030020	extracellular matrix structural constituent conferring tensile strength	0.03797229016055
GO:0050673	epithelial cell proliferation	0.03797229016055
GO:0005581	collagen	0.03797229016055
GO:0008009	chemokine activity	0.03797229016055
GO:0042379	chemokine receptor binding	0.03797229016055
GO:0048592	eye morphogenesis	0.03797229016055
GO:0001664	G-protein-coupled receptor binding	0.03797229016055
GO:0005201	extracellular matrix structural constituent	0.03797229016055
GO:0005604	basement membrane	0.03797229016055
GO:0006817	phosphate transport	0.03797229016055
GO:0043010	camera-type eye development	0.0389555491008782
GO:0044420	extracellular matrix part	0.0390385036440863
GO:0042330	taxis	0.0390385036440863
GO:0006935	chemotaxis	0.0390385036440863
GO:0001654	eye development	0.0390385036440863
GO:0005615	extracellular space	0.0390385036440863
GO:0044421	extracellular region part	0.0414200463043856
GO:0015698	inorganic anion transport	0.0458445979519438

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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