MCL coexpression mm9:2724

Phase1 CAGE Peaks

	Short description
Mm9::chr11:82684589..82684600,-	p9@Rffl
Mm9::chr2:38392125..38392136,+	p@chr2:38392125..38392136 +
Mm9::chr4:43575033..43575044,-	p7@Tln1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0007016	cytoskeletal anchoring	0.0221826630104089
GO:0007044	cell-substrate junction assembly	0.0221826630104089
GO:0030866	cortical actin cytoskeleton organization and biogenesis	0.0221826630104089
GO:0030865	cortical cytoskeleton organization and biogenesis	0.0221826630104089
GO:0007028	cytoplasm organization and biogenesis	0.030162635176774
GO:0005925	focal adhesion	0.0344827269484544
GO:0005924	cell-substrate adherens junction	0.0344827269484544
GO:0001726	ruffle	0.0344827269484544
GO:0030055	cell-matrix junction	0.0344827269484544

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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