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MCL coexpression mm9:3106

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Phase1 CAGE Peaks

 Short description
Mm9::chr17:56749112..56749138,-p1@2410015M20Rik
Mm9::chr2:174289564..174289600,-p1@Atp5e
Mm9::chr9:44728781..44728808,-p1@Atp5l
p1@Gm10221


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005753mitochondrial proton-transporting ATP synthase complex1.92703815712046e-06
GO:0045259proton-transporting ATP synthase complex3.89995817512474e-05
GO:0008553hydrogen-exporting ATPase activity, phosphorylative mechanism3.89995817512474e-05
GO:0015985energy coupled proton transport, down electrochemical gradient3.89995817512474e-05
GO:0015986ATP synthesis coupled proton transport3.89995817512474e-05
GO:0006754ATP biosynthetic process3.89995817512474e-05
GO:0006753nucleoside phosphate metabolic process3.89995817512474e-05
GO:0046933hydrogen ion transporting ATP synthase activity, rotational mechanism3.89995817512474e-05
GO:0016469proton-transporting two-sector ATPase complex3.89995817512474e-05
GO:0046961hydrogen ion transporting ATPase activity, rotational mechanism3.89995817512474e-05
GO:0046034ATP metabolic process3.89995817512474e-05
GO:0044455mitochondrial membrane part3.89995817512474e-05
GO:0009206purine ribonucleoside triphosphate biosynthetic process3.89995817512474e-05
GO:0009201ribonucleoside triphosphate biosynthetic process3.89995817512474e-05
GO:0009145purine nucleoside triphosphate biosynthetic process3.89995817512474e-05
GO:0019829cation-transporting ATPase activity3.89995817512474e-05
GO:0009142nucleoside triphosphate biosynthetic process3.89995817512474e-05
GO:0009205purine ribonucleoside triphosphate metabolic process3.89995817512474e-05
GO:0009199ribonucleoside triphosphate metabolic process3.89995817512474e-05
GO:0009144purine nucleoside triphosphate metabolic process3.89995817512474e-05
GO:0006119oxidative phosphorylation3.89995817512474e-05
GO:0015992proton transport3.99650956933244e-05
GO:0006752group transfer coenzyme metabolic process3.99650956933244e-05
GO:0009141nucleoside triphosphate metabolic process4.08383855605144e-05
GO:0009152purine ribonucleotide biosynthetic process4.08383855605144e-05
GO:0006818hydrogen transport4.08383855605144e-05
GO:0015662ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism4.19819027086957e-05
GO:0009260ribonucleotide biosynthetic process4.19819027086957e-05
GO:0009150purine ribonucleotide metabolic process4.45359929645617e-05
GO:0006164purine nucleotide biosynthetic process4.45359929645617e-05
GO:0009259ribonucleotide metabolic process5.00408295639346e-05
GO:0006163purine nucleotide metabolic process5.42180214831497e-05
GO:0042625ATPase activity, coupled to transmembrane movement of ions6.30667033239424e-05
GO:0009108coenzyme biosynthetic process6.42912828302052e-05
GO:0015078hydrogen ion transmembrane transporter activity7.51544881276979e-05
GO:0015077monovalent inorganic cation transmembrane transporter activity7.91648107790027e-05
GO:0051188cofactor biosynthetic process7.91648107790027e-05
GO:0042626ATPase activity, coupled to transmembrane movement of substances0.000107111204233279
GO:0043492ATPase activity, coupled to movement of substances0.000107111204233279
GO:0016820hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances0.000107111204233279
GO:0009165nucleotide biosynthetic process0.000115637956404115
GO:0015399primary active transmembrane transporter activity0.000121418342178877
GO:0015405P-P-bond-hydrolysis-driven transmembrane transporter activity0.000121418342178877
GO:0022890inorganic cation transmembrane transporter activity0.000124308559908187
GO:0006732coenzyme metabolic process0.000179300194752519
GO:0009117nucleotide metabolic process0.000227474286807915
GO:0051186cofactor metabolic process0.000237681706315475
GO:0055086nucleobase, nucleoside and nucleotide metabolic process0.000250528342635084
GO:0042623ATPase activity, coupled0.000330349398363507
GO:0005743mitochondrial inner membrane0.000335381720865245
GO:0019866organelle inner membrane0.000355217366962539
GO:0031966mitochondrial membrane0.000378341824847984
GO:0016887ATPase activity0.000411222670887404
GO:0005740mitochondrial envelope0.000425589945589233
GO:0015672monovalent inorganic cation transport0.000475978424808754
GO:0022804active transmembrane transporter activity0.000560869526782956
GO:0044429mitochondrial part0.000560869526782956
GO:0031975envelope0.000763466388520182
GO:0031967organelle envelope0.000763466388520182
GO:0006091generation of precursor metabolites and energy0.000893246420430571
GO:0017111nucleoside-triphosphatase activity0.00104497066405382
GO:0008324cation transmembrane transporter activity0.00107020604678131
GO:0006812cation transport0.00107020604678131
GO:0045261proton-transporting ATP synthase complex, catalytic core F(1)0.00107020604678131
GO:0016462pyrophosphatase activity0.00107020604678131
GO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides0.00107020604678131
GO:0016817hydrolase activity, acting on acid anhydrides0.00107020604678131
GO:0033178proton-transporting two-sector ATPase complex, catalytic domain0.00120669429071098
GO:0031090organelle membrane0.00126589650069274
GO:0015075ion transmembrane transporter activity0.00176085405699926
GO:0016310phosphorylation0.00192666858815882
GO:0045263proton-transporting ATP synthase complex, coupling factor F(o)0.00192666858815882
GO:0033177proton-transporting two-sector ATPase complex, proton-transporting domain0.00192666858815882
GO:0006811ion transport0.00207535065240226
GO:0022891substrate-specific transmembrane transporter activity0.00218004542022933
GO:0006793phosphorus metabolic process0.00254745267999148
GO:0006796phosphate metabolic process0.00254745267999148
GO:0022857transmembrane transporter activity0.0028127427760797
GO:0044249cellular biosynthetic process0.00287201864075143
GO:0022892substrate-specific transporter activity0.00329174249201621
GO:0005739mitochondrion0.00335241197753541
GO:0009058biosynthetic process0.00506789884903883
GO:0043234protein complex0.00938678860195132
GO:0032991macromolecular complex0.0147258061915926
GO:0016787hydrolase activity0.0155938648198645
GO:0006810transport0.0190493771834874
GO:0044446intracellular organelle part0.0192146507517743
GO:0044422organelle part0.0192146507517743
GO:0051234establishment of localization0.0194150176935593
GO:0051179localization0.0244681815924056
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0302476379639021
GO:0044444cytoplasmic part0.0326350405189098
GO:0046872metal ion binding0.0405468927473332
GO:0043167ion binding0.0417952230836968



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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