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MCL coexpression mm9:3367

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Phase1 CAGE Peaks

 Short description
Mm9::chr2:72817659..72817725,-p5@Sp3
Mm9::chr5:65827045..65827068,-p3@Ugdh
Mm9::chrX:71491739..71491777,-p1@Flna


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0003979UDP-glucose 6-dehydrogenase activity0.0179119188313569
GO:0030224monocyte differentiation0.0179119188313569
GO:0045022early endosome to late endosome transport0.0179119188313569
GO:0001779natural killer cell differentiation0.0179119188313569
GO:0030851granulocyte differentiation0.0208938037877912
GO:0005080protein kinase C binding0.0208938037877912
GO:0030101natural killer cell activation0.0306926887979374
GO:0016197endosome transport0.0393673692167007
GO:0003690double-stranded DNA binding0.0393673692167007
GO:0051287NAD binding0.0393673692167007
GO:0001702gastrulation with mouth forming second0.0472530987051181
GO:0005802trans-Golgi network0.0472530987051181
GO:0030183B cell differentiation0.0472530987051181
GO:0030218erythrocyte differentiation0.0472530987051181
GO:0002573myeloid leukocyte differentiation0.047670960679287
GO:0019901protein kinase binding0.0496300293415669
GO:0043566structure-specific DNA binding0.0496300293415669
GO:0019900kinase binding0.0496300293415669



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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