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MCL coexpression mm9:640

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:66648428..66648445,+p8@Jmjd1c
Mm9::chr10:66648451..66648471,+p3@Jmjd1c
Mm9::chr10:66648478..66648516,+p2@Jmjd1c
Mm9::chr10:66648821..66648848,+p9@Jmjd1c
Mm9::chr11:116704477..116704546,-p2@Jmjd6
Mm9::chr13:112598892..112598909,-p2@Map3k1
Mm9::chr15:100563143..100563171,-p1@uc007xsd.1
Mm9::chr2:17985518..17985540,+p6@Mllt10
Mm9::chr4:102243124..102243149,+p3@Pde4b
Mm9::chr5:77017688..77017767,+p1@Cep135
Mm9::chr9:72379740..72379757,+p7@Rfx7


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0008632apoptotic program0.00530556953661704
GO:0051213dioxygenase activity0.00530556953661704
GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen0.00530556953661704
GO:0016701oxidoreductase activity, acting on single donors with incorporation of molecular oxygen0.00530556953661704
GO:0043010camera-type eye development0.00664349386223486
GO:0043654recognition of apoptotic cell0.00786563461192289
GO:0008545JUN kinase kinase activity0.00786563461192289
GO:0001654eye development0.00798859897006268
GO:0030838positive regulation of actin filament polymerization0.0183491254813308
GO:0007423sensory organ development0.0200150343694242
GO:0043277apoptotic cell clearance0.0200150343694242
GO:00041153',5'-cyclic-AMP phosphodiesterase activity0.0229313805203644
GO:0004708MAP kinase kinase activity0.0253981304505282
GO:0004712protein serine/threonine/tyrosine kinase activity0.028809073084668
GO:0042116macrophage activation0.028809073084668
GO:0060041retina development in camera-type eye0.028809073084668
GO:0048821erythrocyte development0.028809073084668
GO:0030833regulation of actin filament polymerization0.028809073084668
GO:0007257activation of JNK activity0.028809073084668
GO:0043507positive regulation of JNK activity0.028809073084668
GO:0006910phagocytosis, recognition0.028809073084668
GO:0043506regulation of JNK activity0.0374829797204489
GO:0004709MAP kinase kinase kinase activity0.0389321176228364
GO:0030041actin filament polymerization0.0389321176228364
GO:0008637apoptotic mitochondrial changes0.0417627181151422
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity0.049417168428541
GO:0033077T cell differentiation in the thymus0.049417168428541
GO:0004112cyclic-nucleotide phosphodiesterase activity0.049417168428541
GO:0002274myeloid leukocyte activation0.049417168428541
GO:0008064regulation of actin polymerization and/or depolymerization0.049417168428541
GO:0008270zinc ion binding0.049417168428541
GO:0032535regulation of cellular component size0.049417168428541
GO:0032956regulation of actin cytoskeleton organization and biogenesis0.049417168428541
GO:0030832regulation of actin filament length0.049417168428541
GO:0051493regulation of cytoskeleton organization and biogenesis0.049417168428541
GO:0033043regulation of organelle organization and biogenesis0.049417168428541
GO:0000187activation of MAPK activity0.049417168428541
GO:0030218erythrocyte differentiation0.049417168428541
GO:0006915apoptosis0.049417168428541
GO:0006909phagocytosis0.049417168428541
GO:0012501programmed cell death0.049417168428541
GO:0051258protein polymerization0.049417168428541
GO:0008154actin polymerization and/or depolymerization0.049417168428541
GO:0043406positive regulation of MAP kinase activity0.049417168428541
GO:0008219cell death0.049417168428541
GO:0016265death0.049417168428541
GO:0007254JNK cascade0.049417168428541
GO:0008037cell recognition0.049417168428541
GO:0007179transforming growth factor beta receptor signaling pathway0.049417168428541
GO:0031098stress-activated protein kinase signaling pathway0.049417168428541
GO:0004702receptor signaling protein serine/threonine kinase activity0.049417168428541



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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