MCL coexpression mm9:682

Phase1 CAGE Peaks

	Short description
Mm9::chr3:92189605..92189609,+	p1@Sprr2h
Mm9::chr7:29328946..29328963,+	p@chr7:29328946..29328963 +
Mm9::chr7:29329001..29329020,-	p@chr7:29329001..29329020 -
Mm9::chr7:29329001..29329032,+	p@chr7:29329001..29329032 +
Mm9::chr7:29329057..29329081,-	p@chr7:29329057..29329081 -
Mm9::chr7:29329148..29329160,-	p@chr7:29329148..29329160 -
Mm9::chr7:29329247..29329259,-	p@chr7:29329247..29329259 -
Mm9::chr7:29329460..29329471,-	p@chr7:29329460..29329471 -
Mm9::chr7:29332062..29332106,-	p@chr7:29332062..29332106 -
Mm9::chr7:29332128..29332139,-	p@chr7:29332128..29332139 -
Mm9::chr7:31561413..31561429,+	p2@Dmkn

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0001533	cornified envelope	0.0243606575800651
GO:0007566	embryo implantation	0.0243606575800651
GO:0030216	keratinocyte differentiation	0.0243606575800651
GO:0031424	keratinization	0.0243606575800651
GO:0009913	epidermal cell differentiation	0.0243606575800651
GO:0042698	menstrual cycle	0.0243606575800651
GO:0007565	female pregnancy	0.0243606575800651
GO:0048730	epidermis morphogenesis	0.025469123031589
GO:0032504	multicellular organism reproduction	0.0283313084370023
GO:0048609	reproductive process in a multicellular organism	0.0283313084370023
GO:0048729	tissue morphogenesis	0.0283313084370023
GO:0008544	epidermis development	0.0322601223294536
GO:0007398	ectoderm development	0.0322601223294536

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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