MCL coexpression mm9:1323

Phase1 CAGE Peaks

	Short description
Mm9::chr12:34642682..34642753,+	p2@Twist1
Mm9::chr19:5068077..5068085,+	p3@Cd248
Mm9::chr19:5068087..5068098,+	p2@Cd248
Mm9::chr19:5068101..5068115,+	p1@Cd248
Mm9::chr19:5068117..5068122,+	p4@Cd248
Mm9::chr19:5069431..5069446,+	p@chr19:5069431..5069446 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0045843	negative regulation of striated muscle development	0.0427163126445435
GO:0035115	embryonic forelimb morphogenesis	0.0427163126445435
GO:0016202	regulation of striated muscle development	0.0427163126445435
GO:0035136	forelimb morphogenesis	0.0427163126445435
GO:0035137	hindlimb morphogenesis	0.0449155998709496
GO:0001843	neural tube closure	0.0449155998709496
GO:0014020	primary neural tube formation	0.0449155998709496
GO:0001841	neural tube formation	0.0449155998709496
GO:0001839	neural plate morphogenesis	0.0449155998709496
GO:0001764	neuron migration	0.0449155998709496
GO:0001840	neural plate development	0.0449155998709496
GO:0001838	embryonic epithelial tube formation	0.0449155998709496
GO:0030326	embryonic limb morphogenesis	0.0449155998709496
GO:0035113	embryonic appendage morphogenesis	0.0449155998709496
GO:0021915	neural tube development	0.0449155998709496
GO:0016331	morphogenesis of embryonic epithelium	0.0449155998709496
GO:0035107	appendage morphogenesis	0.0449155998709496
GO:0035108	limb morphogenesis	0.0449155998709496
GO:0048736	appendage development	0.0449155998709496
GO:0060173	limb development	0.0449155998709496
GO:0045596	negative regulation of cell differentiation	0.0460180485381822

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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