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MCL coexpression mm9:1477

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Phase1 CAGE Peaks

 Short description
Mm9::chr7:149844662..149844672,-p8@Igf2
Mm9::chrX:49625849..49625871,-p@chrX:49625849..49625871
-
Mm9::chrX:49967074..49967087,-p2@Gpc3
Mm9::chrX:49967090..49967101,-p3@Gpc3
Mm9::chrX:49967113..49967156,-p1@Gpc3
Mm9::chrX:49967416..49967437,-p4@Gpc3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005159insulin-like growth factor receptor binding0.00723129172825533
GO:0018445prothoracicotrophic hormone activity0.00723129172825533
GO:0030513positive regulation of BMP signaling pathway0.00723129172825533
GO:0008283cell proliferation0.00980652068650246
GO:0009887organ morphogenesis0.00980652068650246
GO:0030510regulation of BMP signaling pathway0.017166789799002
GO:0001658ureteric bud branching0.017166789799002
GO:0005184neuropeptide hormone activity0.017166789799002
GO:0045926negative regulation of growth0.0200748149452051
GO:0030509BMP signaling pathway0.0202856665377052
GO:0001657ureteric bud development0.0202856665377052
GO:0009653anatomical structure morphogenesis0.0202856665377052
GO:0001656metanephros development0.0247492752265413
GO:0048513organ development0.0247492752265413
GO:0048754branching morphogenesis of a tube0.0271467911307937
GO:0001763morphogenesis of a branching structure0.0271467911307937
GO:0009967positive regulation of signal transduction0.0271467911307937
GO:0001822kidney development0.0271467911307937
GO:0048731system development0.0271467911307937
GO:0001655urogenital system development0.0271467911307937
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway0.0271467911307937
GO:0048856anatomical structure development0.0319733690770696
GO:0005615extracellular space0.0319733690770696
GO:0008285negative regulation of cell proliferation0.0319733690770696
GO:0048503GPI anchor binding0.0319733690770696
GO:0005179hormone activity0.0319733690770696
GO:0044421extracellular region part0.0319733690770696
GO:0007275multicellular organismal development0.0321147276600331
GO:0035239tube morphogenesis0.0346178339930072
GO:0040008regulation of growth0.0346178339930072
GO:0008083growth factor activity0.0346178339930072
GO:0035091phosphoinositide binding0.0368969072946606
GO:0005543phospholipid binding0.0425178054670808
GO:0035295tube development0.0425178054670808
GO:0032502developmental process0.0444869144100882



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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