MCL coexpression mm9:1499

Phase1 CAGE Peaks

	Short description
Mm9::chr10:128002960..128003055,-	p1@Pa2g4
Mm9::chr12:29320756..29320770,-	p4@Rps7
Mm9::chr1:144991185..144991219,-	p@chr1:144991185..144991219 -
Mm9::chr3:129534041..129534104,-	p1@Gar1
Mm9::chr6:67216981..67217015,+	p1@Serbp1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0003723	RNA binding	5.96824109179168e-05
GO:0042254	ribosome biogenesis and assembly	5.96824109179168e-05
GO:0022613	ribonucleoprotein complex biogenesis and assembly	0.000141697525165298
GO:0016072	rRNA metabolic process	0.000911051986071722
GO:0006364	rRNA processing	0.000911051986071722
GO:0030529	ribonucleoprotein complex	0.000911051986071722
GO:0001651	dense fibrillar component	0.003067988823755
GO:0030515	snoRNA binding	0.0053356630978383
GO:0003676	nucleic acid binding	0.0053356630978383
GO:0006996	organelle organization and biogenesis	0.00814978272683597
GO:0004239	methionyl aminopeptidase activity	0.00975857397116205
GO:0006396	RNA processing	0.0172167034609127
GO:0050897	cobalt ion binding	0.0181570045119305
GO:0005843	cytosolic small ribosomal subunit (sensu Eukaryota)	0.0201105226744863
GO:0006412	translation	0.0201105226744863
GO:0005732	small nucleolar ribonucleoprotein complex	0.0201105226744863
GO:0032991	macromolecular complex	0.0263349046740459
GO:0019843	rRNA binding	0.0273918789093124
GO:0015935	small ribosomal subunit	0.0338286166136434
GO:0009059	macromolecule biosynthetic process	0.0343384152329058
GO:0016043	cellular component organization and biogenesis	0.0343384152329058
GO:0044452	nucleolar part	0.0344461389135031
GO:0004177	aminopeptidase activity	0.0344461389135031
GO:0005830	cytosolic ribosome (sensu Eukaryota)	0.0427862167485571
GO:0010467	gene expression	0.042860735323676
GO:0044249	cellular biosynthetic process	0.043553479040313
GO:0008235	metalloexopeptidase activity	0.043553479040313
GO:0033279	ribosomal subunit	0.0473159543949282

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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