MCL coexpression mm9:2088

Phase1 CAGE Peaks

	Short description
Mm9::chr13:99585075..99585156,-	p1@Fcho2
Mm9::chr2:120393423..120393462,+	p1@Snap23
Mm9::chr4:108952970..108953005,+	p1@Eps15
Mm9::chr4:135577544..135577580,-	p1@Tceb3

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005484	SNAP receptor activity	0.0358738399344699
GO:0006903	vesicle targeting	0.0358738399344699
GO:0006892	post-Golgi vesicle-mediated transport	0.0358738399344699
GO:0051650	establishment of vesicle localization	0.0358738399344699
GO:0051648	vesicle localization	0.0358738399344699
GO:0030133	transport vesicle	0.0365181508534125
GO:0007033	vacuole organization and biogenesis	0.0365181508534125
GO:0051656	establishment of organelle localization	0.0365181508534125
GO:0006944	membrane fusion	0.0365181508534125
GO:0051640	organelle localization	0.0403249043678184
GO:0003746	translation elongation factor activity	0.0420807394608895
GO:0048193	Golgi vesicle transport	0.0472661293696082

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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