MCL coexpression mm9:3098

Phase1 CAGE Peaks

	Short description
Mm9::chr17:36005663..36005675,+	p@chr17:36005663..36005675 +
Mm9::chr5:114270108..114270129,-	p@chr5:114270108..114270129 -
Mm9::chr5:114270168..114270180,-	p@chr5:114270168..114270180 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0050901	leukocyte tethering or rolling	0.00230099161781625
GO:0045123	cellular extravasation	0.00345148742672437
GO:0007159	leukocyte adhesion	0.00383498602969375
GO:0050900	leukocyte migration	0.00891634251903797
GO:0005529	sugar binding	0.0372760642086232
GO:0016337	cell-cell adhesion	0.0372760642086232
GO:0030246	carbohydrate binding	0.0372760642086232
GO:0016477	cell migration	0.0372760642086232
GO:0051674	localization of cell	0.0372760642086232
GO:0006928	cell motility	0.0372760642086232

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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