MCL coexpression mm9:3102
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Short description | |
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Mm9::chr17:46169315..46169332,- | p1@Vegfa |
Mm9::chr17:87153440..87153451,+ | p4@Epas1 |
Mm9::chr17:87153462..87153473,+ | p3@Epas1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
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GO:0048875 | chemical homeostasis within a tissue | 4.03417333827088e-06 |
GO:0043129 | surfactant homeostasis | 4.03417333827088e-06 |
GO:0001894 | tissue homeostasis | 0.000109258861244836 |
GO:0048871 | multicellular organismal homeostasis | 0.000109258861244836 |
GO:0030324 | lung development | 0.0004661711413113 |
GO:0030323 | respiratory tube development | 0.0004661711413113 |
GO:0048469 | cell maturation | 0.000518871532698554 |
GO:0021700 | developmental maturation | 0.000688330825842467 |
GO:0001525 | angiogenesis | 0.00135144806832074 |
GO:0048514 | blood vessel morphogenesis | 0.00200068103089314 |
GO:0048646 | anatomical structure formation | 0.00202813261994261 |
GO:0035295 | tube development | 0.00202813261994261 |
GO:0001568 | blood vessel development | 0.00202813261994261 |
GO:0001944 | vasculature development | 0.00202813261994261 |
GO:0043618 | regulation of transcription from RNA polymerase II promoter in response to stress | 0.00306790477847712 |
GO:0043619 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress | 0.00306790477847712 |
GO:0042592 | homeostatic process | 0.00409042764426564 |
GO:0043620 | regulation of transcription in response to stress | 0.00409042764426564 |
GO:0001938 | positive regulation of endothelial cell proliferation | 0.00516671442176228 |
GO:0042415 | norepinephrine metabolic process | 0.00613530528528696 |
GO:0009790 | embryonic development | 0.00638302273860601 |
GO:0001936 | regulation of endothelial cell proliferation | 0.00669287693970676 |
GO:0009887 | organ morphogenesis | 0.0072353775816092 |
GO:0001935 | endothelial cell proliferation | 0.00817951056408521 |
GO:0010464 | regulation of mesenchymal cell proliferation | 0.00817951056408521 |
GO:0002053 | positive regulation of mesenchymal cell proliferation | 0.00817951056408521 |
GO:0010463 | mesenchymal cell proliferation | 0.00817951056408521 |
GO:0002027 | regulation of heart rate | 0.00861296007720831 |
GO:0065008 | regulation of biological quality | 0.00861296007720831 |
GO:0001892 | embryonic placenta development | 0.00899696855486349 |
GO:0042462 | eye photoreceptor cell development | 0.0105147846509646 |
GO:0048010 | vascular endothelial growth factor receptor signaling pathway | 0.0105147846509646 |
GO:0048522 | positive regulation of cellular process | 0.0105147846509646 |
GO:0050679 | positive regulation of epithelial cell proliferation | 0.0105147846509646 |
GO:0001974 | blood vessel remodeling | 0.0105147846509646 |
GO:0001754 | eye photoreceptor cell differentiation | 0.0109039222918641 |
GO:0033554 | cellular response to stress | 0.0109753578291056 |
GO:0042461 | photoreceptor cell development | 0.0109753578291056 |
GO:0048593 | camera-type eye morphogenesis | 0.0110396161945117 |
GO:0001541 | ovarian follicle development | 0.0110396161945117 |
GO:0048518 | positive regulation of biological process | 0.0112837140197725 |
GO:0051716 | cellular response to stimulus | 0.0116814931941915 |
GO:0046530 | photoreceptor cell differentiation | 0.0117077211422082 |
GO:0001666 | response to hypoxia | 0.0117077211422082 |
GO:0001569 | patterning of blood vessels | 0.0119923422585296 |
GO:0050678 | regulation of epithelial cell proliferation | 0.01279745022204 |
GO:0001890 | placenta development | 0.0140896508010745 |
GO:0018958 | phenol metabolic process | 0.0142245489797209 |
GO:0022601 | menstrual cycle phase | 0.0142245489797209 |
GO:0006584 | catecholamine metabolic process | 0.0142245489797209 |
GO:0022602 | menstrual cycle process | 0.0144261247562186 |
GO:0050673 | epithelial cell proliferation | 0.0146199217581502 |
GO:0048468 | cell development | 0.0148726082844325 |
GO:0009653 | anatomical structure morphogenesis | 0.0148726082844325 |
GO:0008585 | female gonad development | 0.0148726082844325 |
GO:0008016 | regulation of heart contraction | 0.0148726082844325 |
GO:0046545 | development of primary female sexual characteristics | 0.0148726082844325 |
GO:0030855 | epithelial cell differentiation | 0.0148726082844325 |
GO:0046660 | female sex differentiation | 0.0148726082844325 |
GO:0042133 | neurotransmitter metabolic process | 0.0148726082844325 |
GO:0030218 | erythrocyte differentiation | 0.0148726082844325 |
GO:0009880 | embryonic pattern specification | 0.0155667863259309 |
GO:0042698 | menstrual cycle | 0.0155667863259309 |
GO:0048592 | eye morphogenesis | 0.0163433326762993 |
GO:0003015 | heart process | 0.0163433326762993 |
GO:0060047 | heart contraction | 0.0163433326762993 |
GO:0006979 | response to oxidative stress | 0.0164648462589577 |
GO:0048513 | organ development | 0.0172936112099897 |
GO:0007498 | mesoderm development | 0.0174068148255559 |
GO:0008406 | gonad development | 0.0178574988060467 |
GO:0048608 | reproductive structure development | 0.0182954117040198 |
GO:0048754 | branching morphogenesis of a tube | 0.01947019157141 |
GO:0045137 | development of primary sexual characteristics | 0.01947019157141 |
GO:0008201 | heparin binding | 0.0195377013687176 |
GO:0046982 | protein heterodimerization activity | 0.0196033929751042 |
GO:0001763 | morphogenesis of a branching structure | 0.0203110542148593 |
GO:0007005 | mitochondrion organization and biogenesis | 0.0213177769322386 |
GO:0048609 | reproductive process in a multicellular organism | 0.0218387624449888 |
GO:0032504 | multicellular organism reproduction | 0.0218387624449888 |
GO:0006576 | biogenic amine metabolic process | 0.0218387624449888 |
GO:0007548 | sex differentiation | 0.0218387624449888 |
GO:0048731 | system development | 0.0218387624449888 |
GO:0005539 | glycosaminoglycan binding | 0.0218387624449888 |
GO:0043010 | camera-type eye development | 0.0218697819513702 |
GO:0048869 | cellular developmental process | 0.0219584691782932 |
GO:0030154 | cell differentiation | 0.0219584691782932 |
GO:0006916 | anti-apoptosis | 0.0219584691782932 |
GO:0042445 | hormone metabolic process | 0.0222887623661562 |
GO:0030247 | polysaccharide binding | 0.0222887623661562 |
GO:0001871 | pattern binding | 0.0231270192653428 |
GO:0003006 | reproductive developmental process | 0.0231413334383844 |
GO:0006575 | amino acid derivative metabolic process | 0.023155321817181 |
GO:0001505 | regulation of neurotransmitter levels | 0.0231689949112246 |
GO:0030099 | myeloid cell differentiation | 0.0239618165718334 |
GO:0008015 | blood circulation | 0.0242257011604375 |
GO:0003013 | circulatory system process | 0.0242257011604375 |
GO:0048856 | anatomical structure development | 0.0251152382588263 |
GO:0001654 | eye development | 0.0259731056860296 |
GO:0007601 | visual perception | 0.0271616453275106 |
GO:0050953 | sensory perception of light stimulus | 0.0271616453275106 |
GO:0006725 | aromatic compound metabolic process | 0.0273757671324719 |
GO:0001701 | in utero embryonic development | 0.0285420004890074 |
GO:0048771 | tissue remodeling | 0.0287383541933614 |
GO:0002009 | morphogenesis of an epithelium | 0.0289308801447683 |
GO:0007275 | multicellular organismal development | 0.0290654504882724 |
GO:0016043 | cellular component organization and biogenesis | 0.0334148233593887 |
GO:0035239 | tube morphogenesis | 0.0334148233593887 |
GO:0008083 | growth factor activity | 0.0334148233593887 |
GO:0043066 | negative regulation of apoptosis | 0.0334148233593887 |
GO:0043069 | negative regulation of programmed cell death | 0.0335536499522187 |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 0.0358820092731061 |
GO:0008284 | positive regulation of cell proliferation | 0.0383841027444397 |
GO:0000904 | cellular morphogenesis during differentiation | 0.0397071754564827 |
GO:0007423 | sensory organ development | 0.0397071754564827 |
GO:0008134 | transcription factor binding | 0.0397071754564827 |
GO:0007268 | synaptic transmission | 0.0399930903851556 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 0.040961594372507 |
GO:0046983 | protein dimerization activity | 0.040961594372507 |
GO:0022414 | reproductive process | 0.0422491741585634 |
GO:0030097 | hemopoiesis | 0.0423015347904407 |
GO:0032502 | developmental process | 0.0436736049305149 |
GO:0043009 | chordate embryonic development | 0.0441927376156917 |
GO:0009792 | embryonic development ending in birth or egg hatching | 0.0442620389251412 |
GO:0019226 | transmission of nerve impulse | 0.0442620389251412 |
GO:0048534 | hemopoietic or lymphoid organ development | 0.0452652321650547 |
GO:0007389 | pattern specification process | 0.0452906074995594 |
GO:0045893 | positive regulation of transcription, DNA-dependent | 0.0453155408689713 |
GO:0002520 | immune system development | 0.0474212033197068 |
GO:0006066 | alcohol metabolic process | 0.0479918290596343 |
GO:0030246 | carbohydrate binding | 0.0494754610980777 |
GO:0007167 | enzyme linked receptor protein signaling pathway | 0.0494754610980777 |
Relative expression of the co-expression cluster over median <br>Analyst:
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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
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{{{tfbs_overrepresentation_jaspar}}} |