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MCL coexpression mm9:605

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:70783455..70783480,-p1@Nup88
Mm9::chr11:93747451..93747468,+p4@Mbtd1
Mm9::chr11:97048962..97048994,-p5@Kpnb1
Mm9::chr13:21454695..21454752,+p1@Zscan12
Mm9::chr15:98957049..98957071,+p4@Spats2
Mm9::chr3:103083772..103083796,+p@chr3:103083772..103083796
+
Mm9::chr5:138558139..138558214,+p1@Zscan21
Mm9::chr5:145965392..145965443,+p1@Zkscan5
Mm9::chr7:135019439..135019462,+p@chr7:135019439..135019462
+
Mm9::chr7:54051401..54051455,-p2@Hps5
Mm9::chr9:122832168..122832210,+p1@Zfp105
Mm9::chrX:109714433..109714444,+p2@Zfp711


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0008270zinc ion binding0.0101926500573792
GO:0005643nuclear pore0.0101926500573792
GO:0046930pore complex0.0101926500573792
GO:0044453nuclear membrane part0.0101926500573792
GO:0046914transition metal ion binding0.0101926500573792
GO:0031965nuclear membrane0.0101926500573792
GO:0003676nucleic acid binding0.0154739663567033
GO:0005634nucleus0.0154739663567033
GO:0005635nuclear envelope0.0154739663567033
GO:0006355regulation of transcription, DNA-dependent0.0154739663567033
GO:0006351transcription, DNA-dependent0.0154739663567033
GO:0032774RNA biosynthetic process0.0154739663567033
GO:0003677DNA binding0.0154739663567033
GO:0045449regulation of transcription0.0154739663567033
GO:0019219regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0156932195626997
GO:0006350transcription0.0156932195626997
GO:0010468regulation of gene expression0.0171464204925708
GO:0006610ribosomal protein import into nucleus0.0174735340687904
GO:0031323regulation of cellular metabolic process0.0174735340687904
GO:0043169cation binding0.0174735340687904
GO:0019222regulation of metabolic process0.0195620152981443
GO:0016070RNA metabolic process0.0209717005586246
GO:0046872metal ion binding0.0234416485775474
GO:0043167ion binding0.0250128630190543
GO:0003700transcription factor activity0.0371678022108795
GO:0000059protein import into nucleus, docking0.0371678022108795
GO:0010467gene expression0.0375873581488371
GO:0012505endomembrane system0.0441447714819657
GO:0048477oogenesis0.046583082755119



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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