MCL coexpression mm9:654

Phase1 CAGE Peaks

	Short description
Mm9::chr11:54140546..54140555,+	p@chr11:54140546..54140555 +
Mm9::chr11:83491009..83491013,+	p1@ENSMUST00000118318
Mm9::chr14:57870864..57870876,-	p@chr14:57870864..57870876 -
Mm9::chr1:108980709..108980716,-	p@chr1:108980709..108980716 -
Mm9::chr1:62878785..62878793,-	p@chr1:62878785..62878793 -
Mm9::chr2:154839166..154839201,+	p7@a
Mm9::chr2:154839293..154839297,+	p3@a
Mm9::chr4:144155096..144155104,-	p1@Gm13124
Mm9::chr4:144155170..144155177,-	p2@Gm13124
Mm9::chr4:86279064..86279069,-	p@chr4:86279064..86279069 -
Mm9::chr6:8121358..8121359,-	p@chr6:8121358..8121359 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0032402	melanosome transport	0.00144790288876192
GO:0051904	pigment granule transport	0.00144790288876192
GO:0032401	establishment of melanosome localization	0.00144790288876192
GO:0051905	establishment of pigment granule localization	0.00144790288876192
GO:0032438	melanosome organization and biogenesis	0.00144790288876192
GO:0032400	melanosome localization	0.00144790288876192
GO:0048753	pigment granule organization and biogenesis	0.00144790288876192
GO:0051875	pigment granule localization	0.00152029803320002
GO:0009755	hormone-mediated signaling	0.00168922003688891
GO:0033059	cellular pigmentation	0.00168922003688891
GO:0006582	melanin metabolic process	0.00168922003688891
GO:0042438	melanin biosynthetic process	0.00168922003688891
GO:0051650	establishment of vesicle localization	0.00171520803745644
GO:0051648	vesicle localization	0.00173748346651431
GO:0009725	response to hormone stimulus	0.00216220164721781
GO:0051656	establishment of organelle localization	0.00266052155810004
GO:0046148	pigment biosynthetic process	0.00304059606640004
GO:0051640	organelle localization	0.00304059606640004
GO:0042440	pigment metabolic process	0.00330731501959303
GO:0019748	secondary metabolic process	0.0043581876951734
GO:0009719	response to endogenous stimulus	0.0241317148126988
GO:0042221	response to chemical stimulus	0.0389749132147642

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
zone of skin	3.21e-55	5
skin epidermis	3.21e-55	5
skin of body	3.21e-55	5
integument	3.21e-55	5
surface	3.21e-55	5
outer epithelium	3.21e-55	5
integumental system	3.21e-55	5
enveloping layer of ectoderm	3.21e-55	5
surface structure	7.68e-13	22

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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