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Coexpression cluster:C116

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Full id: C116_myeloma_xeroderma_tonsil_CD19_spleen_lymph_trachea



Phase1 CAGE Peaks

Hg19::chr10:22768515..22768517,+p@chr10:22768515..22768517
+
Hg19::chr10:24738575..24738612,+p5@KIAA1217
Hg19::chr10:24738624..24738634,+p41@KIAA1217
Hg19::chr10:24738638..24738650,+p30@KIAA1217
Hg19::chr10:30536816..30536831,+p@chr10:30536816..30536831
+
Hg19::chr10:54886601..54886610,+p@chr10:54886601..54886610
+
Hg19::chr11:329707..329727,+p@chr11:329707..329727
+
Hg19::chr11:40263097..40263118,-p19@LRRC4C
Hg19::chr11:63856097..63856119,+p@chr11:63856097..63856119
+
Hg19::chr12:109077960..109077962,-p@chr12:109077960..109077962
-
Hg19::chr12:109077992..109078007,-p@chr12:109077992..109078007
-
Hg19::chr12:24972758..24972767,+p@chr12:24972758..24972767
+
Hg19::chr12:24972785..24972806,+p@chr12:24972785..24972806
+
Hg19::chr12:39734783..39734808,-p13@KIF21A
Hg19::chr12:50144308..50144313,+p56@TMBIM6
Hg19::chr12:53585137..53585182,-p@chr12:53585137..53585182
-
Hg19::chr12:68862998..68863016,-p@chr12:68862998..68863016
-
Hg19::chr13:110697682..110697690,-p@chr13:110697682..110697690
-
Hg19::chr13:67922393..67922399,-p@chr13:67922393..67922399
-
Hg19::chr13:90939632..90939664,+p@chr13:90939632..90939664
+
Hg19::chr14:106326477..106326489,+p@chr14:106326477..106326489
+
Hg19::chr14:106327649..106327660,-p4@DQ431661
Hg19::chr14:106327661..106327684,-p1@DQ431661
Hg19::chr14:106327728..106327733,-p6@DQ431661
Hg19::chr14:106329578..106329585,-p@chr14:106329578..106329585
-
Hg19::chr14:95242011..95242039,-p@chr14:95242011..95242039
-
Hg19::chr15:101069325..101069330,-p7@CERS3
Hg19::chr15:101069375..101069384,-p5@CERS3
Hg19::chr15:52773284..52773310,-p@chr15:52773284..52773310
-
Hg19::chr16:79608731..79608732,-p@chr16:79608731..79608732
-
Hg19::chr16:79616145..79616150,+p@chr16:79616145..79616150
+
Hg19::chr16:79619926..79619964,-p@chr16:79619926..79619964
-
Hg19::chr16:79622153..79622168,-p@chr16:79622153..79622168
-
Hg19::chr16:79622919..79622925,+p@chr16:79622919..79622925
+
Hg19::chr16:79626038..79626040,-p@chr16:79626038..79626040
-
Hg19::chr16:79747712..79747717,+p@chr16:79747712..79747717
+
Hg19::chr16:79747740..79747756,+p@chr16:79747740..79747756
+
Hg19::chr16:79747772..79747775,+p@chr16:79747772..79747775
+
Hg19::chr16:79747801..79747810,+p@chr16:79747801..79747810
+
Hg19::chr16:79747831..79747843,+p@chr16:79747831..79747843
+
Hg19::chr16:82817605..82817639,-p@chr16:82817605..82817639
-
Hg19::chr17:32718335..32718349,-p@chr17:32718335..32718349
-
Hg19::chr17:54428183..54428231,+p@chr17:54428183..54428231
+
Hg19::chr18:74203923..74203952,+p@chr18:74203923..74203952
+
Hg19::chr19:29026154..29026177,-p@chr19:29026154..29026177
-
Hg19::chr19:29026221..29026229,-p@chr19:29026221..29026229
-
Hg19::chr19:39587779..39587782,-p@chr19:39587779..39587782
-
Hg19::chr19:49961714..49961731,+p@chr19:49961714..49961731
+
Hg19::chr1:117087319..117087347,+p@chr1:117087319..117087347
+
Hg19::chr1:12223524..12223541,+p@chr1:12223524..12223541
+
Hg19::chr1:169805602..169805613,+p@chr1:169805602..169805613
+
Hg19::chr1:198607833..198607849,+p4@PTPRC
Hg19::chr1:198607856..198607888,+p7@PTPRC
Hg19::chr1:237932758..237932788,+p@chr1:237932758..237932788
+
Hg19::chr1:85049201..85049203,+p@chr1:85049201..85049203
+
Hg19::chr1:91328490..91328494,-p@chr1:91328490..91328494
-
Hg19::chr1:98039634..98039638,-p@chr1:98039634..98039638
-
Hg19::chr21:20322533..20322550,+p@chr21:20322533..20322550
+
Hg19::chr21:34488410..34488418,-p@chr21:34488410..34488418
-
Hg19::chr22:17094724..17094734,+p@chr22:17094724..17094734
+
Hg19::chr22:17094735..17094738,+p@chr22:17094735..17094738
+
Hg19::chr22:17094751..17094772,+p@chr22:17094751..17094772
+
Hg19::chr22:23054857..23054874,+p1@IGLV3-21
Hg19::chr22:23243367..23243395,-p@chr22:23243367..23243395
-
Hg19::chr2:144992180..144992184,+p@chr2:144992180..144992184
+
Hg19::chr2:144998671..144998676,-p@chr2:144998671..144998676
-
Hg19::chr2:159842523..159842528,+p@chr2:159842523..159842528
+
Hg19::chr2:165615049..165615056,-p@chr2:165615049..165615056
-
Hg19::chr2:167992478..167992486,+p36@XIRP2
Hg19::chr2:196710966..196710988,-p@chr2:196710966..196710988
-
Hg19::chr2:234875226..234875238,+p8@TRPM8
Hg19::chr2:43768420..43768427,-p5@THADA
Hg19::chr2:45640375..45640385,-p@chr2:45640375..45640385
-
Hg19::chr2:46768787..46768818,-p5@ATP6V1E2
Hg19::chr2:86206348..86206353,-p@chr2:86206348..86206353
-
Hg19::chr2:86438444..86438455,-p@chr2:86438444..86438455
-
Hg19::chr3:103710821..103710827,+p@chr3:103710821..103710827
+
Hg19::chr3:124654200..124654240,-p@chr3:124654200..124654240
-
Hg19::chr3:130766656..130766677,+p@chr3:130766656..130766677
+
Hg19::chr3:150316485..150316531,-p@chr3:150316485..150316531
-
Hg19::chr3:15531393..15531399,-p@chr3:15531393..15531399
-
Hg19::chr3:156822906..156822926,-p@chr3:156822906..156822926
-
Hg19::chr3:179674518..179674534,+p@chr3:179674518..179674534
+
Hg19::chr3:192414271..192414317,+p@chr3:192414271..192414317
+
Hg19::chr3:42237516..42237521,-p@chr3:42237516..42237521
-
Hg19::chr3:42237526..42237535,-p@chr3:42237526..42237535
-
Hg19::chr3:45637435..45637462,-p@chr3:45637435..45637462
-
Hg19::chr3:56207902..56207938,-p3@ERC2
Hg19::chr3:56207965..56207974,-p16@ERC2
Hg19::chr4:162586046..162586050,-p3@FSTL5
Hg19::chr4:26143606..26143611,+p@chr4:26143606..26143611
+
Hg19::chr4:46093758..46093781,-p@chr4:46093758..46093781
-
Hg19::chr4:66233218..66233227,-p@chr4:66233218..66233227
-
Hg19::chr4:66305202..66305228,+p@chr4:66305202..66305228
+
Hg19::chr4:66306454..66306463,+p@chr4:66306454..66306463
+
Hg19::chr4:66308007..66308019,+p@chr4:66308007..66308019
+
Hg19::chr4:76524891..76524896,-p@chr4:76524891..76524896
-
Hg19::chr4:76525013..76525031,-p@chr4:76525013..76525031
-
Hg19::chr5:10801166..10801179,+p@chr5:10801166..10801179
+
Hg19::chr5:10801244..10801250,+p@chr5:10801244..10801250
+
Hg19::chr5:115626749..115626788,+p6@COMMD10
Hg19::chr5:155803272..155803281,-p@chr5:155803272..155803281
-
Hg19::chr5:162627023..162627034,-p@chr5:162627023..162627034
-
Hg19::chr5:166711816..166711823,+p48@ODZ2
Hg19::chr5:32586539..32586555,+p8@SUB1
Hg19::chr5:53115516..53115545,-p1@ENST00000504552
Hg19::chr5:90830457..90830471,+p@chr5:90830457..90830471
+
Hg19::chr5:90830481..90830492,+p@chr5:90830481..90830492
+
Hg19::chr6:101902366..101902383,-p@chr6:101902366..101902383
-
Hg19::chr6:106616288..106616291,+p@chr6:106616288..106616291
+
Hg19::chr6:124669719..124669754,+p@chr6:124669719..124669754
+
Hg19::chr6:3339264..3339271,-p@chr6:3339264..3339271
-
Hg19::chr6:389797..389804,-p@chr6:389797..389804
-
Hg19::chr7:12632710..12632720,-p@chr7:12632710..12632720
-
Hg19::chr7:135679523..135679530,+p@chr7:135679523..135679530
+
Hg19::chr7:81399847..81399856,-p12@HGF
Hg19::chr7:81432906..81432917,-p@chr7:81432906..81432917
-
Hg19::chr7:81432923..81432934,-p@chr7:81432923..81432934
-
Hg19::chr7:81432944..81432949,-p@chr7:81432944..81432949
-
Hg19::chr7:81432964..81432970,-p@chr7:81432964..81432970
-
Hg19::chr7:81432972..81432980,-p@chr7:81432972..81432980
-
Hg19::chr7:81501187..81501225,+p@chr7:81501187..81501225
+
Hg19::chr7:83946145..83946165,-p@chr7:83946145..83946165
-
Hg19::chr7:85402705..85402715,-p@chr7:85402705..85402715
-
Hg19::chr7:85406054..85406063,-p@chr7:85406054..85406063
-
Hg19::chr7:85406080..85406102,-p@chr7:85406080..85406102
-
Hg19::chr7:85406211..85406217,+p@chr7:85406211..85406217
+
Hg19::chr7:85411224..85411232,-p@chr7:85411224..85411232
-
Hg19::chr7:87848253..87848304,-p@chr7:87848253..87848304
-
Hg19::chr7:92398240..92398284,-p@chr7:92398240..92398284
-
Hg19::chr8:108972923..108972934,-p@chr8:108972923..108972934
-
Hg19::chr8:108972941..108972947,-p@chr8:108972941..108972947
-
Hg19::chr8:116599724..116599735,-p@chr8:116599724..116599735
-
Hg19::chr8:116599752..116599766,-p@chr8:116599752..116599766
-
Hg19::chr8:116599856..116599857,-p@chr8:116599856..116599857
-
Hg19::chr8:131054630..131054638,-p@chr8:131054630..131054638
-
Hg19::chr8:135513449..135513453,+p@chr8:135513449..135513453
+
Hg19::chr8:136769076..136769077,-p@chr8:136769076..136769077
-
Hg19::chr8:136769096..136769108,-p@chr8:136769096..136769108
-
Hg19::chr8:140614315..140614330,-p2@KCNK9
Hg19::chr8:140614358..140614378,-p1@KCNK9
Hg19::chr8:144610064..144610088,-p@chr8:144610064..144610088
-
Hg19::chr8:144610164..144610167,+p@chr8:144610164..144610167
+
Hg19::chr8:1920058..1920066,+p@chr8:1920058..1920066
+
Hg19::chr8:48947486..48947496,+p@chr8:48947486..48947496
+
Hg19::chr8:48947511..48947526,+p@chr8:48947511..48947526
+
Hg19::chr8:48947527..48947530,+p@chr8:48947527..48947530
+
Hg19::chr8:62747328..62747346,+p1@ENST00000517953
Hg19::chr8:62747349..62747356,+p2@ENST00000517953
Hg19::chr9:130691048..130691049,-p14@PIP5KL1
Hg19::chr9:130691054..130691069,-p2@PIP5KL1
Hg19::chr9:130691070..130691090,-p1@PIP5KL1
Hg19::chr9:130691101..130691110,-p11@PIP5KL1
Hg19::chr9:134552082..134552097,-p@chr9:134552082..134552097
-
Hg19::chr9:22033489..22033492,+p@chr9:22033489..22033492
+
Hg19::chr9:30925270..30925284,-p@chr9:30925270..30925284
-
Hg19::chr9:75772986..75773020,+p13@ANXA1
Hg19::chr9:98615236..98615243,+p@chr9:98615236..98615243
+
Hg19::chrX:68796176..68796181,-p@chrX:68796176..68796181
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br><br>disease_data<br>


Cell Type
Ontology termp-valuen
bone marrow cell3.81e-2110
lymphocyte of B lineage1.01e-0924
pro-B cell1.01e-0924
Disease
Ontology termp-valuen
bone marrow cancer5.42e-1951
myeloma5.42e-1951


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
BATF#10538213.217068161247652.60778973073894e-069.15171208631198e-05



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data