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MCL coexpression mm9:493

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Phase1 CAGE Peaks

 Short description
Mm9::chr12:80081660..80081667,-p@chr12:80081660..80081667
-
Mm9::chr13:41942916..41942930,-p7@9530008L14Rik
Mm9::chr14:59819868..59819890,+p5@Rcbtb1
Mm9::chr17:34741829..34741866,+p6@Agpat1
Mm9::chr17:34741874..34741896,+p8@Agpat1
Mm9::chr17:34742434..34742443,+p16@Agpat1
Mm9::chr19:32135843..32135852,-p8@Asah2
Mm9::chr19:32135856..32135871,-p5@Asah2
Mm9::chr2:29659138..29659154,+p@chr2:29659138..29659154
+
Mm9::chr2:29659170..29659180,+p@chr2:29659170..29659180
+
Mm9::chr7:52970037..52970048,-p@chr7:52970037..52970048
-
Mm9::chr7:52970050..52970066,-p@chr7:52970050..52970066
-
Mm9::chr7:52970068..52970099,-p4@Sphk2
Mm9::chr8:26864686..26864722,-p2@Ddhd2
Mm9::chr8:26864824..26864896,-p1@Ddhd2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0006629lipid metabolic process0.000103886642702824
GO:0006643membrane lipid metabolic process0.00102577637870691
GO:0044255cellular lipid metabolic process0.00102577637870691
GO:0006665sphingolipid metabolic process0.00433710004817991
GO:0046467membrane lipid biosynthetic process0.00771790938475867
GO:0017050D-erythro-sphingosine kinase activity0.00771790938475867
GO:0046511sphinganine biosynthetic process0.00771790938475867
GO:0006669sphinganine-1-phosphate biosynthetic process0.00771790938475867
GO:0006667sphinganine metabolic process0.0112242048383209
GO:0008481sphinganine kinase activity0.0112242048383209
GO:0006668sphinganine-1-phosphate metabolic process0.0112242048383209
GO:0006670sphingosine metabolic process0.0154307449992403
GO:0017040ceramidase activity0.0264396648314999
GO:0046520sphingoid biosynthetic process0.0264396648314999
GO:0008610lipid biosynthetic process0.0346849533115712
GO:00038411-acylglycerol-3-phosphate O-acyltransferase activity0.0346849533115712
GO:0004467long-chain-fatty-acid-CoA ligase activity0.0381467145022446
GO:0007205protein kinase C activation0.0381467145022446
GO:0004143diacylglycerol kinase activity0.0381467145022446
GO:0015645fatty-acid ligase activity0.0381467145022446
GO:0016411acylglycerol O-acyltransferase activity0.0381467145022446
GO:0001676long-chain fatty acid metabolic process0.0392073114929924
GO:0030148sphingolipid biosynthetic process0.0401748033217997
GO:0044238primary metabolic process0.048660483088478



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
intestine8.39e-2731
gastrointestinal system9.96e-2147
mucosa6.80e-1615
intestinal mucosa3.45e-1313
anatomical wall3.45e-1313
wall of intestine3.45e-1313
gastrointestinal system mucosa3.45e-1313
organ component layer1.49e-0824
epithelium of mucosa4.26e-089
gastrointestinal system epithelium4.26e-089
intestinal epithelium4.26e-089


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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