MCL coexpression mm9:1080

Phase1 CAGE Peaks

	Short description
Mm9::chr11:57786904..57786931,+	p@chr11:57786904..57786931 +
Mm9::chr1:92811641..92811691,+	p1@Mlph
Mm9::chr1:92811692..92811712,+	p2@Mlph
Mm9::chr3:100293431..100293483,+	p1@ENSMUST00000122898
Mm9::chr4:57833953..57833973,+	p@chr4:57833953..57833973 +
Mm9::chr4:73364442..73364446,-	p@chr4:73364442..73364446 -
Mm9::chr4:73436897..73436957,-	p1@Rasef

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0031489	myosin V binding	0.00872320892633674
GO:0051010	microtubule plus-end binding	0.00872320892633674
GO:0032400	melanosome localization	0.00872320892633674
GO:0051875	pigment granule localization	0.00872320892633674
GO:0017022	myosin binding	0.00872320892633674
GO:0033059	cellular pigmentation	0.00872320892633674
GO:0048770	pigment granule	0.00872320892633674
GO:0042470	melanosome	0.00872320892633674
GO:0015031	protein transport	0.00872320892633674
GO:0045184	establishment of protein localization	0.00872320892633674
GO:0051648	vesicle localization	0.00872320892633674
GO:0008104	protein localization	0.00899445867963646
GO:0033036	macromolecule localization	0.00899445867963646
GO:0030318	melanocyte differentiation	0.00906120316010084
GO:0050931	pigment cell differentiation	0.00906120316010084
GO:0017137	Rab GTPase binding	0.00949375496459958
GO:0051640	organelle localization	0.0126947457716614
GO:0048066	pigmentation during development	0.0128768858571382
GO:0008017	microtubule binding	0.0190989957619239
GO:0017016	Ras GTPase binding	0.0190989957619239
GO:0031267	small GTPase binding	0.0190989957619239
GO:0051020	GTPase binding	0.0190989957619239
GO:0015631	tubulin binding	0.0190989957619239
GO:0019899	enzyme binding	0.0441657620092987
GO:0006810	transport	0.0447072859655827
GO:0051234	establishment of localization	0.0453412544770146
GO:0016023	cytoplasmic membrane-bound vesicle	0.0497916355086711
GO:0006605	protein targeting	0.0497916355086711
GO:0051179	localization	0.0497916355086711
GO:0015629	actin cytoskeleton	0.0497916355086711
GO:0031988	membrane-bound vesicle	0.0497916355086711

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
gastrointestinal system	8.12e-12	47
intestine	1.18e-09	31
endoderm-derived structure	8.97e-09	118
endoderm	8.97e-09	118
presumptive endoderm	8.97e-09	118
adult organism	2.06e-08	51
anatomical space	2.59e-08	57
digestive system	4.84e-08	116
digestive tract	4.84e-08	116
primitive gut	4.84e-08	116
subdivision of digestive tract	1.63e-07	114
pancreas	5.03e-07	12

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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