MCL coexpression mm9:3017

Phase1 CAGE Peaks

	Short description
Mm9::chr15:85690182..85690205,+	p2@Gtse1
Mm9::chr8:23295957..23295992,-	p@chr8:23295957..23295992 -
Mm9::chr8:23296230..23296289,-	p1@Ckap2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005874	microtubule	0.00261428840081875
GO:0015630	microtubule cytoskeleton	0.00293594168573624
GO:0044430	cytoskeletal part	0.0064806113126937
GO:0005856	cytoskeleton	0.0132735468844601
GO:0043228	non-membrane-bound organelle	0.0256807070186535
GO:0043232	intracellular non-membrane-bound organelle	0.0256807070186535
GO:0044446	intracellular organelle part	0.0474081102660598
GO:0044422	organelle part	0.0474081102660598

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
autonomic neuron	5.50e-07	9

Uber Anatomy

Ontology term	p-value	n
autonomic nervous system	5.50e-07	9

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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