MCL coexpression mm9:730
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr14:118412218..118412229,- | p@chr14:118412218..118412229 - |
| Mm9::chr14:118429907..118429909,- | p@chr14:118429907..118429909 - |
| Mm9::chr14:118451457..118451475,- | p1@Dct |
| Mm9::chr15:10930471..10930491,+ | p1@Slc45a2 |
| Mm9::chr15:10930503..10930518,+ | p2@Slc45a2 |
| Mm9::chr19:29772395..29772417,+ | p1@Mlana |
| Mm9::chr4:80480108..80480125,+ | p1@Tyrp1 |
| Mm9::chr4:80480190..80480199,+ | p5@Tyrp1 |
| Mm9::chr4:80480202..80480217,+ | p3@Tyrp1 |
| Mm9::chr6:97941770..97941784,+ | p4@Mitf |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0006583 | melanin biosynthetic process from tyrosine | 6.78820209071475e-09 |
| GO:0006582 | melanin metabolic process | 1.35741721685762e-08 |
| GO:0042438 | melanin biosynthetic process | 1.35741721685762e-08 |
| GO:0006570 | tyrosine metabolic process | 2.42608404590985e-08 |
| GO:0009072 | aromatic amino acid family metabolic process | 1.46956811269265e-07 |
| GO:0046148 | pigment biosynthetic process | 1.46956811269265e-07 |
| GO:0048066 | pigmentation during development | 1.77004589903175e-07 |
| GO:0042440 | pigment metabolic process | 1.90510097451336e-07 |
| GO:0019748 | secondary metabolic process | 4.64698917360445e-07 |
| GO:0006725 | aromatic compound metabolic process | 7.9118639122626e-06 |
| GO:0006520 | amino acid metabolic process | 4.92698596534237e-05 |
| GO:0006519 | amino acid and derivative metabolic process | 0.000103407251882155 |
| GO:0009308 | amine metabolic process | 0.000150135472305523 |
| GO:0006807 | nitrogen compound metabolic process | 0.000173712652337567 |
| GO:0019752 | carboxylic acid metabolic process | 0.000310035712120609 |
| GO:0006082 | organic acid metabolic process | 0.000310035712120609 |
| GO:0004167 | dopachrome isomerase activity | 0.000991906161063647 |
| GO:0043437 | butanoic acid metabolic process | 0.000991906161063647 |
| GO:0043438 | acetoacetic acid metabolic process | 0.000991906161063647 |
| GO:0044249 | cellular biosynthetic process | 0.00161887872627728 |
| GO:0009058 | biosynthetic process | 0.00377523513334822 |
| GO:0032438 | melanosome organization and biogenesis | 0.00409565704379738 |
| GO:0048753 | pigment granule organization and biogenesis | 0.00409565704379738 |
| GO:0033059 | cellular pigmentation | 0.0070626860823427 |
| GO:0016863 | intramolecular oxidoreductase activity, transposing C |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| eye | 6.27e-18 | 9 |
| camera-type eye | 6.27e-18 | 9 |
| simple eye | 6.27e-18 | 9 |
| immature eye | 6.27e-18 | 9 |
| ocular region | 6.27e-18 | 9 |
| visual system | 6.27e-18 | 9 |
| face | 6.27e-18 | 9 |
| optic cup | 6.27e-18 | 9 |
| optic vesicle | 6.27e-18 | 9 |
| eye primordium | 6.27e-18 | 9 |
| subdivision of head | 2.89e-14 | 11 |
| sense organ | 6.80e-13 | 12 |
| sensory system | 6.80e-13 | 12 |
| entire sense organ system | 6.80e-13 | 12 |
| head | 9.81e-12 | 13 |
| ectodermal placode | 9.81e-12 | 13 |
| zone of skin | 1.06e-10 | 5 |
| skin epidermis | 1.06e-10 | 5 |
| skin of body | 1.06e-10 | 5 |
| integument | 1.06e-10 | 5 |
| surface | 1.06e-10 | 5 |
| outer epithelium | 1.06e-10 | 5 |
| integumental system | 1.06e-10 | 5 |
| enveloping layer of ectoderm | 1.06e-10 | 5 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.0214004 |
| MA0004.1 | 0.360508 |
| MA0006.1 | 0.210471 |
| MA0007.1 | 0.346734 |
| MA0009.1 | 0.780842 |
| MA0014.1 | 0.342463 |
| MA0017.1 | 0.233089 |
| MA0019.1 | 0.603066 |
| MA0024.1 | 0.737933 |
| MA0025.1 | 1.01089 |
| MA0027.1 | 2.42079 |
| MA0028.1 | 0.219287 |
| MA0029.1 | 0.716673 |
| MA0030.1 | 0.723093 |
| MA0031.1 | 0.688336 |
| MA0038.1 | 1.24163 |
| MA0040.1 | 0.79313 |
| MA0041.1 | 0.291712 |
| MA0042.1 | 0.279998 |
| MA0043.1 | 0.875991 |
| MA0046.1 | 0.816137 |
| MA0048.1 | 0.066679 |
| MA0050.1 | 0.396459 |
| MA0051.1 | 0.504875 |
| MA0052.1 | 0.801048 |
| MA0055.1 | 0.0660514 |
| MA0056.1 | 0 |
| MA0057.1 | 0.059732 |
| MA0058.1 | 0.273976 |
| MA0059.1 | 0.28489 |
| MA0060.1 | 0.145297 |
| MA0061.1 | 0.16896 |
| MA0063.1 | 0 |
| MA0066.1 | 0.485868 |
| MA0067.1 | 1.12095 |
| MA0068.1 | 1.26706 |
| MA0069.1 | 0.801381 |
| MA0070.1 | 0.791856 |
| MA0071.1 | 1.02422 |
| MA0072.1 | 0.783532 |
| MA0073.1 | 0.460904 |
| MA0074.1 | 0.451832 |
| MA0076.1 | 0.249619 |
| MA0077.1 | 0.762273 |
| MA0078.1 | 0.536502 |
| MA0081.1 | 0.305576 |
| MA0083.1 | 0.875209 |
| MA0084.1 | 1.44691 |
| MA0087.1 | 0.832758 |
| MA0088.1 | 0.14959 |
| MA0089.1 | 0 |
| MA0090.1 | 0.329158 |
| MA0091.1 | 0.372635 |
| MA0092.1 | 2.39515 |
| MA0093.1 | 0.226349 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.440912 |
| MA0101.1 | 0.292867 |
| MA0103.1 | 0.242398 |
| MA0105.1 | 0.0911942 |
| MA0106.1 | 0.543967 |
| MA0107.1 | 0.237082 |
| MA0108.2 | 0.625209 |
| MA0109.1 | 0 |
| MA0111.1 | 0.90605 |
| MA0113.1 | 0.516916 |
| MA0114.1 | 0.500166 |
| MA0115.1 | 0.878749 |
| MA0116.1 | 0.210297 |
| MA0117.1 | 0.846964 |
| MA0119.1 | 0.293392 |
| MA0122.1 | 0.866511 |
| MA0124.1 | 1.06819 |
| MA0125.1 | 0.994853 |
| MA0130.1 | 0 |
| MA0131.1 | 0.598671 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.911905 |
| MA0136.1 | 0.470672 |
| MA0139.1 | 0.121562 |
| MA0140.1 | 1.12231 |
| MA0141.1 | 0.259554 |
| MA0142.1 | 0.674191 |
| MA0143.1 | 0.53259 |
| MA0144.1 | 0.506239 |
| MA0145.1 | 0.664015 |
| MA0146.1 | 0.00739145 |
| MA0147.1 | 0.179496 |
| MA0148.1 | 0.375491 |
| MA0149.1 | 3.10307 |
| MA0062.2 | 0.0948004 |
| MA0035.2 | 1.1319 |
| MA0039.2 | 0.026226 |
| MA0138.2 | 0.590987 |
| MA0002.2 | 0.391079 |
| MA0137.2 | 0.257017 |
| MA0104.2 | 0.134457 |
| MA0047.2 | 0.495607 |
| MA0112.2 | 0.0422488 |
| MA0065.2 | 0.0424448 |
| MA0150.1 | 0.346631 |
| MA0151.1 | 0 |
| MA0152.1 | 0.495709 |
| MA0153.1 | 0.92832 |
| MA0154.1 | 0.232525 |
| MA0155.1 | 0.0498353 |
| MA0156.1 | 0.248865 |
| MA0157.1 | 0.642984 |
| MA0158.1 | 0 |
| MA0159.1 | 0.187774 |
| MA0160.1 | 1.74983 |
| MA0161.1 | 0 |
| MA0162.1 | 0.00972009 |
| MA0163.1 | 0.679942 |
| MA0164.1 | 1.1874 |
| MA0080.2 | 0.237846 |
| MA0018.2 | 0.480226 |
| MA0099.2 | 0.584892 |
| MA0079.2 | 0.340295 |
| MA0102.2 | 1.49914 |
| MA0258.1 | 0.156336 |
| MA0259.1 | 0.170828 |
| MA0442.1 | 0 |
