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UBERON:0000946

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Name:cardial valve
Namespace:FANTOM
Definition:"Flap of tissue that prevents regurgitation of blood from the ventricles to the atria or from the pulmonary arteries or aorta to the ventricles." [Wikipedia:Cardiac_valve]
Xrefs:
links:

BTO:0000564
EMAPA:17869
EV:0100024
FMA:7110
GAID:176
galen:HeartValve
MA:0000086
MESH:A.07.541.510
ncithesaurus:Cardiac_Valve
OpenCyc:Mx4rv8oyuJwpEbGdrcN5Y29ycA
SCTID:181285005
TAO:0005065
VHOG:0000818
XAO:0004126

ZFA:0005065
Synonyms: "cardiac valve" RELATED []
"heart valve" EXACT []
"heart valves" RELATED []
"stomodaeal valve" RELATED []
"valve of heart" EXACT []
Comments:Terminology notes: Rector et al: One might be tempted to define 遯ｶ蠕Ｆart valve遯ｶ� equivalently to 遯ｶ蠢ｻalve in the heart遯ｶ�, and 遯ｶ蠢ｻalve遯ｶ� as a 遯ｶ蠕ｭtructure which functions as a valve遯ｶ�. But this combination results in the 遯ｶ蠖ｷoramen ovale遯ｶ� being classified as a kind of 遯ｶ蠕Ｆart valve遯ｶ�, since it is undoubtedly located in the heart and functions as a valve
Alt_id: UBERON:FBbt_00003140-FMA_7110-MA_0000086-ZFA_0005065
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0003978(valve),UBERON:0004120(mesoderm-derived structure),UBERON:0010313(neural crest-derived structure)
develops_from:UBERON:0002062(endocardial cushion)
part_of:UBERON:0000948(heart)



Children

is a:UBERON:0002133 (atrioventricular valve),UBERON:0005623 (semi-lunar valve)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000946 (cardial valve), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.41e-147FFCP PHASE2:Hg19::chr7:25815812..25815822,-#_aac90d3c520eadd4af247c8e3429d064p@chr7:25815812..25815822, -
5.41e-147FFCP PHASE1:Hg19::chr7:25815812..25815822,-#_aac90d3c520eadd4af247c8e3429d064p@chr7:25815812..25815822, -
8.98e-131FFCP PHASE2:Hg19::chr12:3373147..3373149,-#_1bd6a3da174a95494e24f306d86e5f78p@chr12:3373147..3373149, -
8.98e-131FFCP PHASE1:Hg19::chr12:3373147..3373149,-#_1bd6a3da174a95494e24f306d86e5f78p@chr12:3373147..3373149, -
7.78e-118FFCP PHASE1:Hg19::chr1:20355975..20355980,-#_a6d25361541833e0eb9961d7414aee57p@chr1:20355975..20355980, -
7.78e-118FFCP PHASE2:Hg19::chr1:20355975..20355980,-#_a6d25361541833e0eb9961d7414aee57p@chr1:20355975..20355980, -
5.69e-99FFCP PHASE2:Hg19::chr1:237331032..237331036,+#_167319a64fcf9d8179940392d300a125p@chr1:237331032..237331036, +
5.69e-99FFCP PHASE1:Hg19::chr1:237331032..237331036,+#_167319a64fcf9d8179940392d300a125p@chr1:237331032..237331036, +
1.52e-87FFCP PHASE2:Hg19::chr6:6739548..6739577,-#_61abd1fbb754fc413f9bc0dc5fb54054p@chr6:6739548..6739577, -
1.52e-87FFCP PHASE2:Hg19::chr2:18116344..18116353,+#_61abd1fbb754fc413f9bc0dc5fb54054p@chr2:18116344..18116353, +
1.52e-87FFCP PHASE2:Hg19::chr1:11907265..11907271,-#_61abd1fbb754fc413f9bc0dc5fb54054p9@NPPA
1.52e-87FFCP PHASE1:Hg19::chr6:6739548..6739577,-#_61abd1fbb754fc413f9bc0dc5fb54054p@chr6:6739548..6739577, -
1.52e-87FFCP PHASE1:Hg19::chr2:18116344..18116353,+#_61abd1fbb754fc413f9bc0dc5fb54054p@chr2:18116344..18116353, +
1.52e-87FFCP PHASE1:Hg19::chr1:11907265..11907271,-#_61abd1fbb754fc413f9bc0dc5fb54054p9@NPPA
7.21e-85FFCP PHASE1:Hg19::chrX:112324334..112324339,-#_8b34961e69b4570c1d6ae825faba2833p@chrX:112324334..112324339, -
7.21e-85FFCP PHASE2:Hg19::chrX:112324334..112324339,-#_8b34961e69b4570c1d6ae825faba2833p@chrX:112324334..112324339, -
1.71e-84FFCP PHASE2:Hg19::chr2:220491902..220491915,+#_3baa1cff2858dc986dd7a224d9dbb359p11@SLC4A3
1.71e-84FFCP PHASE1:Hg19::chr2:220491902..220491915,+#_3baa1cff2858dc986dd7a224d9dbb359p11@SLC4A3
2.27e-84FFCP PHASE1:Hg19::chr2:179533457..179533461,-#_f9f30b4cf7ae4c1da6c4e2a1c00c335ap@chr2:179533457..179533461, -
2.27e-84FFCP PHASE2:Hg19::chr2:179533457..179533461,-#_f9f30b4cf7ae4c1da6c4e2a1c00c335ap@chr2:179533457..179533461, -
3.03e-84FFCP PHASE2:Hg19::chr2:179398102..179398109,-#_4ad2a5645c070ed34033ee371f7100cfp@chr2:179398102..179398109, -
3.03e-84FFCP PHASE1:Hg19::chr2:179398102..179398109,-#_4ad2a5645c070ed34033ee371f7100cfp@chr2:179398102..179398109, -
7.81e-75FFCP PHASE1:Hg19::chr5:123739302..123739319,-#_0a8081385e6fdd57939734f15efaa059p@chr5:123739302..123739319, -
7.81e-75FFCP PHASE2:Hg19::chr5:123739302..123739319,-#_0a8081385e6fdd57939734f15efaa059p@chr5:123739302..123739319, -
1.01e-74FFCP PHASE2:Hg19::chr18:64271475..64271484,-#_7801d8746e1e713410d65c23dccf2de6p6@CDH19
1.01e-74FFCP PHASE1:Hg19::chr18:64271475..64271484,-#_7801d8746e1e713410d65c23dccf2de6p6@CDH19
1.29e-74FFCP PHASE1:Hg19::chr7:35286774..35286778,-#_9e21d1ea59caa763f9cb239d146bc5a4p@chr7:35286774..35286778, -
1.29e-74FFCP PHASE2:Hg19::chr7:35286774..35286778,-#_9e21d1ea59caa763f9cb239d146bc5a4p@chr7:35286774..35286778, -
1.66e-74FFCP PHASE1:Hg19::chr6:129355052..129355056,+#_99715bf386dfbe2d46633afb00d8b00ep@chr6:129355052..129355056, +
1.66e-74FFCP PHASE2:Hg19::chr6:129355052..129355056,+#_99715bf386dfbe2d46633afb00d8b00ep@chr6:129355052..129355056, +
2.75e-74FFCP PHASE1:Hg19::chr3:16940540..16940554,+#_03fdfd24a92a546c9fe4ae0f55e07d80p@chr3:16940540..16940554, +
2.75e-74FFCP PHASE2:Hg19::chr3:16940540..16940554,+#_03fdfd24a92a546c9fe4ae0f55e07d80p@chr3:16940540..16940554, +
3.54e-74FFCP PHASE2:Hg19::chr20:33565465..33565475,+#_eea2de820f120696ed0916da9aee812cp9@MYH7B
3.54e-74FFCP PHASE2:Hg19::chr1:201328779..201328797,-#_eea2de820f120696ed0916da9aee812cp@chr1:201328779..201328797, -
3.54e-74FFCP PHASE1:Hg19::chr19:55661803..55661807,-#_eea2de820f120696ed0916da9aee812cp@chr19:55661803..55661807, -
3.54e-74FFCP PHASE1:Hg19::chr3:131523446..131523459,-#_eea2de820f120696ed0916da9aee812cp@chr3:131523446..131523459, -
3.54e-74FFCP PHASE2:Hg19::chr19:55661803..55661807,-#_eea2de820f120696ed0916da9aee812cp@chr19:55661803..55661807, -
3.54e-74FFCP PHASE1:Hg19::chr1:201328779..201328797,-#_eea2de820f120696ed0916da9aee812cp@chr1:201328779..201328797, -
3.54e-74FFCP PHASE2:Hg19::chr3:131523446..131523459,-#_eea2de820f120696ed0916da9aee812cp@chr3:131523446..131523459, -
3.54e-74FFCP PHASE1:Hg19::chr20:33565465..33565475,+#_eea2de820f120696ed0916da9aee812cp9@MYH7B
5.84e-74FFCP PHASE2:Hg19::chr6:36812121..36812130,-#_1b0a2d5e26890699ef7c1f3cf3a9c031p@chr6:36812121..36812130, -
5.84e-74FFCP PHASE1:Hg19::chr6:36812121..36812130,-#_1b0a2d5e26890699ef7c1f3cf3a9c031p@chr6:36812121..36812130, -
7.51e-74FFCP PHASE2:Hg19::chr14:105939326..105939337,+#_4eb65f370a26c4b7621a5d0b6985d7c9p16@CRIP2
7.51e-74FFCP PHASE1:Hg19::chr14:105939326..105939337,+#_4eb65f370a26c4b7621a5d0b6985d7c9p16@CRIP2
9.64e-74FFCP PHASE1:Hg19::chr1:206838422..206838456,+#_fde3edb786bd2a9755576e422c370d54p@chr1:206838422..206838456, +
9.64e-74FFCP PHASE2:Hg19::chr1:206838422..206838456,+#_fde3edb786bd2a9755576e422c370d54p@chr1:206838422..206838456, +
1.24e-73FFCP PHASE2:Hg19::chr1:231983543..231983554,-#_c1c1fe95fb49a7e74bef7278837479b5p@chr1:231983543..231983554, -
1.24e-73FFCP PHASE1:Hg19::chr1:231983543..231983554,-#_c1c1fe95fb49a7e74bef7278837479b5p@chr1:231983543..231983554, -
1.54e-66FFCP PHASE1:Hg19::chr1:201328328..201328343,-#_3b155da8f1cb608e9b66fb804e36a48ep@chr1:201328328..201328343, -
1.54e-66FFCP PHASE2:Hg19::chr1:201328328..201328343,-#_3b155da8f1cb608e9b66fb804e36a48ep@chr1:201328328..201328343, -
1.71e-66FFCP PHASE1:Hg19::chr11:47367243..47367257,-#_af12ed1bed68ff2f73f19da6281cef7fp@chr11:47367243..47367257, -
1.71e-66FFCP PHASE2:Hg19::chr1:237214095..237214115,+#_af12ed1bed68ff2f73f19da6281cef7fp@chr1:237214095..237214115, +
1.71e-66FFCP PHASE1:Hg19::chr1:237214095..237214115,+#_af12ed1bed68ff2f73f19da6281cef7fp@chr1:237214095..237214115, +
1.71e-66FFCP PHASE2:Hg19::chr11:47367243..47367257,-#_af12ed1bed68ff2f73f19da6281cef7fp@chr11:47367243..47367257, -
2.39e-66FFCP PHASE2:Hg19::chr5:99390735..99390743,-#_94e6bce68f071870bc2288f5e052ed1bp@chr5:99390735..99390743, -
2.39e-66FFCP PHASE2:Hg19::chr15:86272097..86272099,+#_94e6bce68f071870bc2288f5e052ed1bp@chr15:86272097..86272099, +
2.39e-66FFCP PHASE2:Hg19::chr10:92678409..92678410,-#_94e6bce68f071870bc2288f5e052ed1bp@chr10:92678409..92678410, -
2.39e-66FFCP PHASE1:Hg19::chr5:99390735..99390743,-#_94e6bce68f071870bc2288f5e052ed1bp@chr5:99390735..99390743, -
2.39e-66FFCP PHASE1:Hg19::chr15:86272097..86272099,+#_94e6bce68f071870bc2288f5e052ed1bp@chr15:86272097..86272099, +
2.39e-66FFCP PHASE1:Hg19::chr10:92678409..92678410,-#_94e6bce68f071870bc2288f5e052ed1bp@chr10:92678409..92678410, -
2.4e-66FFCP PHASE1:Hg19::chr12:4735761..4735787,-#_ead09772fb6e63d175155af2d7b90bd7p@chr12:4735761..4735787, -
2.4e-66FFCP PHASE1:Hg19::chr2:159976509..159976519,+#_ead09772fb6e63d175155af2d7b90bd7p@chr2:159976509..159976519, +
2.4e-66FFCP PHASE2:Hg19::chr1:237996521..237996532,+#_ead09772fb6e63d175155af2d7b90bd7p@chr1:237996521..237996532, +
2.4e-66FFCP PHASE2:Hg19::chr12:114886577..114886589,-#_ead09772fb6e63d175155af2d7b90bd7p@chr12:114886577..114886589, -
2.4e-66FFCP PHASE2:Hg19::chr2:159976509..159976519,+#_ead09772fb6e63d175155af2d7b90bd7p@chr2:159976509..159976519, +
2.4e-66FFCP PHASE1:Hg19::chr12:114886577..114886589,-#_ead09772fb6e63d175155af2d7b90bd7p@chr12:114886577..114886589, -
2.4e-66FFCP PHASE1:Hg19::chr1:237996521..237996532,+#_ead09772fb6e63d175155af2d7b90bd7p@chr1:237996521..237996532, +
2.4e-66FFCP PHASE2:Hg19::chr12:4735761..4735787,-#_ead09772fb6e63d175155af2d7b90bd7p@chr12:4735761..4735787, -
2.41e-66FFCP PHASE1:Hg19::chr1:237207955..237207959,+#_bd3c766cba3acd67493366ef029ea50ap@chr1:237207955..237207959, +
2.41e-66FFCP PHASE2:Hg19::chr2:40480968..40480972,-#_bd3c766cba3acd67493366ef029ea50ap@chr2:40480968..40480972, -
2.41e-66FFCP PHASE2:Hg19::chr1:237207955..237207959,+#_bd3c766cba3acd67493366ef029ea50ap@chr1:237207955..237207959, +
2.41e-66FFCP PHASE1:Hg19::chr2:40480968..40480972,-#_bd3c766cba3acd67493366ef029ea50ap@chr2:40480968..40480972, -
3.01e-66FFCP PHASE1:Hg19::chr4:62999501..62999517,+#_c47123891327cbed2345713e9a25806bp@chr4:62999501..62999517, +
3.01e-66FFCP PHASE2:Hg19::chr4:62999501..62999517,+#_c47123891327cbed2345713e9a25806bp@chr4:62999501..62999517, +
3.35e-66FFCP PHASE1:Hg19::chr7:35253487..35253489,-#_a5ffcdc8ed06864c43e1e8ad28a1c184p@chr7:35253487..35253489, -
3.35e-66FFCP PHASE2:Hg19::chr7:44179972..44179982,-#_a5ffcdc8ed06864c43e1e8ad28a1c184p2@MYL7
3.35e-66FFCP PHASE1:Hg19::chr1:11905830..11905839,-#_a5ffcdc8ed06864c43e1e8ad28a1c184p@chr1:11905830..11905839, -
3.35e-66FFCP PHASE1:Hg19::chr9:38650254..38650266,+#_a5ffcdc8ed06864c43e1e8ad28a1c184p@chr9:38650254..38650266, +
3.35e-66FFCP PHASE1:Hg19::chr7:44178491..44178498,-#_a5ffcdc8ed06864c43e1e8ad28a1c184p@chr7:44178491..44178498, -
3.35e-66FFCP PHASE2:Hg19::chr5:65736120..65736128,-#_a5ffcdc8ed06864c43e1e8ad28a1c184p@chr5:65736120..65736128, -
3.35e-66FFCP PHASE2:Hg19::chr7:35253487..35253489,-#_a5ffcdc8ed06864c43e1e8ad28a1c184p@chr7:35253487..35253489, -
3.35e-66FFCP PHASE2:Hg19::chr1:11905830..11905839,-#_a5ffcdc8ed06864c43e1e8ad28a1c184p@chr1:11905830..11905839, -
3.35e-66FFCP PHASE1:Hg19::chr7:44179972..44179982,-#_a5ffcdc8ed06864c43e1e8ad28a1c184p2@MYL7
3.35e-66FFCP PHASE2:Hg19::chr9:38650254..38650266,+#_a5ffcdc8ed06864c43e1e8ad28a1c184p@chr9:38650254..38650266, +
3.35e-66FFCP PHASE2:Hg19::chr7:44178491..44178498,-#_a5ffcdc8ed06864c43e1e8ad28a1c184p@chr7:44178491..44178498, -
3.35e-66FFCP PHASE1:Hg19::chr5:65736120..65736128,-#_a5ffcdc8ed06864c43e1e8ad28a1c184p@chr5:65736120..65736128, -
4.68e-66FFCP PHASE2:Hg19::chr10:112524543..112524547,+#_dfdfd7851678d01bf754b47963456454p@chr10:112524543..112524547, +
4.68e-66FFCP PHASE2:Hg19::chr7:44180643..44180652,-#_dfdfd7851678d01bf754b47963456454p3@MYL7
4.68e-66FFCP PHASE1:Hg19::chr10:112524543..112524547,+#_dfdfd7851678d01bf754b47963456454p@chr10:112524543..112524547, +
4.68e-66FFCP PHASE1:Hg19::chr7:44180643..44180652,-#_dfdfd7851678d01bf754b47963456454p3@MYL7
5.88e-66FFCP PHASE1:Hg19::chr6:36812225..36812238,-#_ff4e3324d482634d29320ee086b3d951p@chr6:36812225..36812238, -
5.88e-66FFCP PHASE2:Hg19::chr6:36812225..36812238,-#_ff4e3324d482634d29320ee086b3d951p@chr6:36812225..36812238, -
6.53e-66FFCP PHASE2:Hg19::chr4:62999459..62999462,+#_b767606d3341e9dcd6e6e741b5e693e5p@chr4:62999459..62999462, +
6.53e-66FFCP PHASE1:Hg19::chr2:168104544..168104551,+#_b767606d3341e9dcd6e6e741b5e693e5p52@XIRP2
6.53e-66FFCP PHASE2:Hg19::chr2:168104544..168104551,+#_b767606d3341e9dcd6e6e741b5e693e5p52@XIRP2
6.53e-66FFCP PHASE1:Hg19::chr4:62999459..62999462,+#_b767606d3341e9dcd6e6e741b5e693e5p@chr4:62999459..62999462, +
1.15e-65FFCP PHASE2:Hg19::chr10:127569398..127569410,-#_f0d78779a8aefb68742b5d22ac175a68p5@DHX32
1.15e-65FFCP PHASE2:Hg19::chrX:121555838..121555874,+#_f0d78779a8aefb68742b5d22ac175a68p@chrX:121555838..121555874, +
1.15e-65FFCP PHASE1:Hg19::chr7:123302841..123302854,+#_f0d78779a8aefb68742b5d22ac175a68p@chr7:123302841..123302854, +
1.15e-65FFCP PHASE1:Hg19::chr10:127569398..127569410,-#_f0d78779a8aefb68742b5d22ac175a68p5@DHX32

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