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CL:0000169

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Name:type B pancreatic cell
Namespace:cell
Definition:"A cell that secretes insulin and is located towards the center of the islets of Langerhans." [GOC:tfm, ISBN:0517223651]
Xrefs:
links:

BTO:0000783
FMA:70586

MA:0002419
Synonyms: "B-cell of pancreatic islet" EXACT [FMA:70586]
"beta cell islet" RELATED [MA:0002419]
"beta cell of pancreatic islet" EXACT [FMA:70586]
"insulin-secreting cell" EXACT [FMA:70586]
"pancreatic B cell" EXACT []
"pancreatic B-cell" EXACT [FMA:70586]
"pancreatic beta cell" EXACT []
"pancreatic beta cell" EXACT [FMA:70586]
"pancreatic islet core" EXACT [MA:0002419]
"type B enteroendocrine cell" EXACT [FMA:70586]
Comments:Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression.


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000164(enteroendocrine cell),CL:0000168(beta cell;;insulin secreting cell)
develops_from:CL:0002351(progenitor cell of endocrine pancreas)
part_of:UBERON:0000006(islet of Langerhans)



Children


is a:FF:0000129 (pancreatic beta cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.




Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000169 (type B pancreatic cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


No analysis results for this cluster