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Coexpression cluster:C1502


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Full id: C1502_mature_Hepatocyte_argyrophil_hepatoblastoma_liver_hepatocellular_Adipocyte

Phase1 CAGE Peaks


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0019166trans-2-enoyl-CoA reductase (NADPH) activity0.0174844729335235

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br>disease_data<br>

Uber Anatomy
Ontology termp-valuen
adult organism1.43e-29115
neural tube3.92e-1657
neural rod3.92e-1657
future spinal cord3.92e-1657
neural keel3.92e-1657
regional part of brain1.80e-1459
regional part of nervous system2.05e-1494
nervous system2.05e-1494
future brain3.38e-1469
central nervous system6.60e-1482
anterior neural tube1.06e-1342
regional part of forebrain3.28e-1341
future forebrain3.28e-1341
neural plate5.42e-1286
presumptive neural plate5.42e-1286
gray matter7.40e-1134
brain grey matter7.40e-1134
pre-chordal neural plate1.05e-1061
cerebral hemisphere1.82e-1032
regional part of telencephalon2.65e-1033
regional part of cerebral cortex3.67e-1022
subdivision of digestive tract4.78e-09129
endodermal part of digestive tract4.78e-09129
anterior region of body1.12e-08129
craniocervical region1.12e-08129
cerebral cortex1.54e-0825
multi-tissue structure6.99e-08347
digestive system9.12e-07155
digestive tract9.12e-07155
primitive gut9.12e-07155
Ontology termp-valuen
cell type cancer2.21e-13143

Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs

JASPAR motifs



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.