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Coexpression cluster:C1810

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Full id: C1810_testis_liver_Hepatocyte_small_colon_seminal_Prostate



Phase1 CAGE Peaks

Hg19::chr19:1497289..1497305,+p@chr19:1497289..1497305
+
Hg19::chr19:1497299..1497314,-p3@CU678890
Hg19::chr19:1497555..1497564,+p@chr19:1497555..1497564
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Hg19::chr19:1497650..1497658,+p@chr19:1497650..1497658
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Hg19::chr1:167883334..167883352,-p2@ADCY10


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
metabolising cell1.52e-1212
endopolyploid cell1.52e-1212
parenchymal cell1.52e-1212
polyploid cell1.52e-1212
hepatocyte1.52e-1212
Uber Anatomy
Ontology termp-valuen
liver4.11e-1219
digestive gland4.11e-1219
liver bud4.11e-1219
hepatic diverticulum1.93e-1022
liver primordium1.93e-1022
digestive tract diverticulum5.58e-1023
epithelial sac3.62e-0925
epithelium of foregut-midgut junction3.62e-0925
anatomical boundary3.62e-0925
hepatobiliary system3.62e-0925
foregut-midgut junction3.62e-0925
septum transversum3.62e-0925
subdivision of digestive tract4.75e-09118
sac8.28e-0926
intestine2.67e-0817
small intestine2.83e-084
gut epithelium1.33e-0754
exocrine gland2.34e-0731
exocrine system2.34e-0731
digestive system5.15e-07145
digestive tract5.15e-07145
primitive gut5.15e-07145


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.