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Coexpression cluster:C252

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Full id: C252_hepatic_Olfactory_sacrococcigeal_leiomyoma_normal_Synoviocyte_glioblastoma



Phase1 CAGE Peaks

Hg19::chr13:60923837..60923842,+p@chr13:60923837..60923842
+
Hg19::chr2:217536828..217536834,+p@chr2:217536828..217536834
+
Hg19::chr2:217536938..217536983,+p@chr2:217536938..217536983
+
Hg19::chr2:217536997..217537017,+p@chr2:217536997..217537017
+
Hg19::chr2:217537650..217537688,-p7@IGFBP5
Hg19::chr2:217538410..217538421,-p41@IGFBP5
Hg19::chr2:217538489..217538501,-p30@IGFBP5
Hg19::chr2:217539038..217539095,-p@chr2:217539038..217539095
-
Hg19::chr2:217539159..217539181,-p@chr2:217539159..217539181
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Hg19::chr2:217539667..217539679,-p@chr2:217539667..217539679
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Hg19::chr2:217540148..217540164,-p@chr2:217540148..217540164
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Hg19::chr2:217540173..217540184,-p@chr2:217540173..217540184
-
Hg19::chr2:217540186..217540197,-p@chr2:217540186..217540197
-
Hg19::chr2:217540204..217540217,-p@chr2:217540204..217540217
-
Hg19::chr2:217540397..217540408,-p47@IGFBP5
Hg19::chr2:217540482..217540541,-p3@IGFBP5
Hg19::chr2:217540844..217540856,-p17@IGFBP5
Hg19::chr2:217540885..217540897,-p40@IGFBP5
Hg19::chr2:217540938..217540949,-p42@IGFBP5
Hg19::chr2:217541024..217541035,-p21@IGFBP5
Hg19::chr2:217541074..217541178,+p@chr2:217541074..217541178
+
Hg19::chr2:217541219..217541237,-p22@IGFBP5
Hg19::chr2:217541242..217541256,-p32@IGFBP5
Hg19::chr2:217541259..217541290,-p16@IGFBP5
Hg19::chr2:217541295..217541337,-p4@IGFBP5
Hg19::chr2:217541338..217541373,-p10@IGFBP5
Hg19::chr2:217541386..217541454,-p@chr2:217541386..217541454
-
Hg19::chr2:217541453..217541486,+p@chr2:217541453..217541486
+
Hg19::chr2:217541501..217541514,+p@chr2:217541501..217541514
+
Hg19::chr2:217541503..217541520,-p@chr2:217541503..217541520
-
Hg19::chr2:217541580..217541591,-p@chr2:217541580..217541591
-
Hg19::chr2:217542874..217542895,-p@chr2:217542874..217542895
-
Hg19::chr2:217542897..217542920,-p@chr2:217542897..217542920
-
Hg19::chr2:217542923..217542939,-p@chr2:217542923..217542939
-
Hg19::chr2:217542944..217542963,-p@chr2:217542944..217542963
-
Hg19::chr2:217543623..217543642,-p@chr2:217543623..217543642
-
Hg19::chr2:217543637..217543648,+p@chr2:217543637..217543648
+
Hg19::chr2:217543669..217543701,+p@chr2:217543669..217543701
+
Hg19::chr2:217543717..217543731,-p@chr2:217543717..217543731
-
Hg19::chr2:217543738..217543773,+p@chr2:217543738..217543773
+
Hg19::chr2:217559189..217559207,-p29@IGFBP5
Hg19::chr2:217559232..217559274,-p6@IGFBP5
Hg19::chr2:217559547..217559566,-p13@IGFBP5
Hg19::chr2:217559626..217559641,-p9@IGFBP5
Hg19::chr2:217559705..217559716,-p23@IGFBP5
Hg19::chr2:217559768..217559787,-p12@IGFBP5
Hg19::chr2:217559807..217559818,-p19@IGFBP5
Hg19::chr2:217559893..217559904,-p39@IGFBP5
Hg19::chr2:217559980..217559987,-p37@IGFBP5
Hg19::chr2:217560017..217560035,-p26@IGFBP5
Hg19::chr2:217560039..217560069,-p2@IGFBP5
Hg19::chr2:217560263..217560278,-p1@IGFBP5


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
organism subdivision1.15e-21365
adult organism2.71e-15115
multi-cellular organism1.16e-14659
multi-tissue structure3.14e-13347
anatomical cluster1.60e-11286
cell layer1.65e-11312
epithelium2.25e-11309
anatomical conduit3.48e-11241
tube1.46e-09194
muscle tissue1.67e-0963
musculature1.67e-0963
musculature of body1.67e-0963
anatomical system2.32e-09625
trunk mesenchyme2.61e-09143
anatomical group3.92e-09626
skeletal muscle tissue5.22e-0961
striated muscle tissue5.22e-0961
myotome5.22e-0961
regional part of nervous system5.60e-0994
nervous system5.60e-0994
trunk6.85e-09216
central nervous system8.88e-0982
ectoderm-derived structure9.03e-09169
ectoderm9.05e-09173
presumptive ectoderm9.05e-09173
brain1.49e-0869
future brain1.49e-0869
regional part of brain2.31e-0859
dermomyotome2.46e-0870
somite3.33e-0883
paraxial mesoderm3.33e-0883
presomitic mesoderm3.33e-0883
presumptive segmental plate3.33e-0883
trunk paraxial mesoderm3.33e-0883
presumptive paraxial mesoderm3.33e-0883
neural tube3.62e-0857
neural rod3.62e-0857
future spinal cord3.62e-0857
neural keel3.62e-0857
anterior region of body8.91e-08129
craniocervical region8.91e-08129
head1.21e-07123
embryo2.17e-07612
neural plate2.92e-0786
presumptive neural plate2.92e-0786
neurectoderm3.50e-0790
organ3.70e-07511


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data