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|full_id=C2621_migratory_Eosinophils_Neutrophils_CD14_hairy_immature_Mast
|full_id=C2621_migratory_Eosinophils_Neutrophils_CD14_hairy_immature_Mast
|id=C2621
|id=C2621
|ontology_enrichment_celltype=CL:0000738!1.32e-70!140;CL:0000037!1.81e-68!172;CL:0000566!1.81e-68!172;CL:0000988!1.20e-64!182;CL:0002032!4.51e-64!165;CL:0000837!4.51e-64!165;CL:0002031!5.24e-55!124;CL:0002087!1.58e-53!119;CL:0000763!4.37e-41!112;CL:0000049!4.37e-41!112;CL:0000766!1.40e-40!76;CL:0000557!6.21e-36!71;CL:0000839!4.46e-33!70;CL:0002057!1.83e-32!42;CL:0002009!2.11e-32!65;CL:0002194!7.42e-31!63;CL:0000576!7.42e-31!63;CL:0000040!7.42e-31!63;CL:0000559!7.42e-31!63;CL:0000860!8.29e-29!45;CL:0000542!2.06e-19!53;CL:0000051!2.06e-19!53;CL:0000838!8.18e-19!52;CL:0000945!3.74e-14!24;CL:0000826!3.74e-14!24;CL:0000134!3.47e-09!358;CL:0000451!7.80e-09!10;CL:0002320!3.13e-08!365;CL:0002393!3.15e-08!9;CL:0002397!3.15e-08!9;CL:0000094!3.29e-08!8;CL:0000236!9.44e-08!14;CL:0000990!1.67e-07!8
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002390!2.24e-42!102;UBERON:0003061!2.24e-42!102;UBERON:0002193!2.93e-39!112;UBERON:0002371!8.92e-32!80;UBERON:0001474!1.99e-27!86;UBERON:0002405!1.70e-22!115;UBERON:0007023!6.19e-22!115;UBERON:0004765!5.31e-20!101;UBERON:0001434!5.31e-20!101;UBERON:0001049!2.49e-14!57;UBERON:0005068!2.49e-14!57;UBERON:0006241!2.49e-14!57;UBERON:0007135!2.49e-14!57;UBERON:0002780!2.00e-13!41;UBERON:0001890!2.00e-13!41;UBERON:0006240!2.00e-13!41;UBERON:0003080!8.61e-13!42;UBERON:0002616!6.18e-11!59;UBERON:0002020!6.26e-11!34;UBERON:0003528!6.26e-11!34;UBERON:0001893!6.61e-11!34;UBERON:0002791!1.83e-10!33;UBERON:0001869!3.19e-10!32;UBERON:0002619!3.01e-09!22;UBERON:0003081!5.77e-09!216;UBERON:0001950!2.54e-08!20;UBERON:0000955!3.79e-08!69;UBERON:0006238!3.79e-08!69;UBERON:0000178!5.99e-08!15;UBERON:0000179!5.99e-08!15;UBERON:0000463!5.99e-08!15;UBERON:0003075!6.26e-08!86;UBERON:0007284!6.26e-08!86;UBERON:0000956!6.36e-08!25;UBERON:0000203!6.36e-08!25;UBERON:0001017!1.38e-07!82;UBERON:0002384!1.88e-07!375;UBERON:0005743!4.44e-07!86;UBERON:0002346!6.39e-07!90
}}
}}

Revision as of 14:26, 21 May 2012


Full id: C2621_migratory_Eosinophils_Neutrophils_CD14_hairy_immature_Mast



Phase1 CAGE Peaks

Hg19::chr20:4803297..4803323,-p@chr20:4803297..4803323
-
Hg19::chr22:35806477..35806519,+p3@MCM5
Hg19::chr22:35806599..35806615,+p8@MCM5
Hg19::chr6:12061235..12061270,+p@chr6:12061235..12061270
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
leukocyte1.32e-70140
hematopoietic stem cell1.81e-68172
angioblastic mesenchymal cell1.81e-68172
hematopoietic cell1.20e-64182
hematopoietic oligopotent progenitor cell4.51e-64165
hematopoietic multipotent progenitor cell4.51e-64165
hematopoietic lineage restricted progenitor cell5.24e-55124
nongranular leukocyte1.58e-53119
myeloid cell4.37e-41112
common myeloid progenitor4.37e-41112
myeloid leukocyte1.40e-4076
granulocyte monocyte progenitor cell6.21e-3671
myeloid lineage restricted progenitor cell4.46e-3370
CD14-positive, CD16-negative classical monocyte1.83e-3242
macrophage dendritic cell progenitor2.11e-3265
monopoietic cell7.42e-3163
monocyte7.42e-3163
monoblast7.42e-3163
promonocyte7.42e-3163
classical monocyte8.29e-2945
lymphocyte2.06e-1953
common lymphoid progenitor2.06e-1953
lymphoid lineage restricted progenitor cell8.18e-1952
lymphocyte of B lineage3.74e-1424
pro-B cell3.74e-1424
mesenchymal cell3.47e-09358
dendritic cell7.80e-0910
connective tissue cell3.13e-08365
intermediate monocyte3.15e-089
CD14-positive, CD16-positive monocyte3.15e-089
granulocyte3.29e-088
B cell9.44e-0814
conventional dendritic cell1.67e-078
Uber Anatomy
Ontology termp-valuen
hematopoietic system2.24e-42102
blood island2.24e-42102
hemolymphoid system2.93e-39112
bone marrow8.92e-3280
bone element1.99e-2786
immune system1.70e-22115
adult organism6.19e-22115
skeletal element5.31e-20101
skeletal system5.31e-20101
neural tube2.49e-1457
neural rod2.49e-1457
future spinal cord2.49e-1457
neural keel2.49e-1457
regional part of forebrain2.00e-1341
forebrain2.00e-1341
future forebrain2.00e-1341
anterior neural tube8.61e-1342
regional part of brain6.18e-1159
gray matter6.26e-1134
brain grey matter6.26e-1134
telencephalon6.61e-1134
regional part of telencephalon1.83e-1033
cerebral hemisphere3.19e-1032
regional part of cerebral cortex3.01e-0922
lateral plate mesoderm5.77e-09216
neocortex2.54e-0820
brain3.79e-0869
future brain3.79e-0869
blood5.99e-0815
haemolymphatic fluid5.99e-0815
organism substance5.99e-0815
neural plate6.26e-0886
presumptive neural plate6.26e-0886
cerebral cortex6.36e-0825
pallium6.36e-0825
central nervous system1.38e-0782
connective tissue1.88e-07375
neurectoderm6.39e-0790


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.