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Coexpression cluster:C2910

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Full id: C2910_smallcell_parotid_submaxillary_Hepatocyte_pancreas_liver_salivary



Phase1 CAGE Peaks

Hg19::chr7:99567028..99567032,-p@chr7:99567028..99567032
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Hg19::chr7:99569415..99569428,-p@chr7:99569415..99569428
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Hg19::chr7:99569457..99569465,-p@chr7:99569457..99569465
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Hg19::chr7:99569468..99569478,-p@chr7:99569468..99569478
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism3.24e-33115
exocrine gland3.22e-1331
exocrine system3.22e-1331
saliva-secreting gland6.08e-126
gland of oral region6.08e-126
gland of foregut6.08e-126
oral gland6.08e-126
oral cavity6.08e-126
neural tube3.91e-0957
neural rod3.91e-0957
future spinal cord3.91e-0957
neural keel3.91e-0957
anatomical conduit6.75e-09241
gray matter6.87e-0934
brain grey matter6.87e-0934
subdivision of digestive tract1.46e-08129
endodermal part of digestive tract1.46e-08129
gland1.79e-0859
regional part of brain1.13e-0759
mixed ectoderm/mesoderm/endoderm-derived structure1.74e-0718
foregut2.71e-0798
anterior region of body4.24e-07129
craniocervical region4.24e-07129
digestive tract diverticulum4.68e-0723
cerebral cortex6.67e-0725
pallium6.67e-0725
regional part of telencephalon6.95e-0733
valve7.07e-073
cardiac mesenchyme7.07e-073
cardial valve7.07e-073
tunica intima7.07e-073
heart layer7.07e-073
endocardium7.07e-073
endocardial cushion7.07e-073
presumptive endocardium7.07e-073
regional part of cerebral cortex8.21e-0722
anatomical cluster8.67e-07286
gland of gut8.71e-0710
anterior neural tube8.75e-0742


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.