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{{Coexpression_clusters
 
{{Coexpression_clusters
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|full_id=C302_acute_peripheral_Neutrophils_NK_myelodysplastic_CD34_carcinoid
 
|full_id=C302_acute_peripheral_Neutrophils_NK_myelodysplastic_CD34_carcinoid
 
|gostat_on_coexpression_clusters=GO:0004961!thromboxane A2 receptor activity!0.00883080183680678!6915$GO:0004960!thromboxane receptor activity!0.024053182288869!6915$GO:0015116!sulfate transmembrane transporter activity!0.024053182288869!115019$GO:0008271!secondary active sulfate transmembrane transporter activity!0.024053182288869!115019$GO:0004522!pancreatic ribonuclease activity!0.024053182288869!6037$GO:0004953!icosanoid receptor activity!0.024053182288869!6915$GO:0004954!prostanoid receptor activity!0.024053182288869!6915$GO:0008272!sulfate transport!0.024053182288869!115019$GO:0016892!endoribonuclease activity, producing 3'-phosphomonoesters!0.024053182288869!6037$GO:0007585!respiratory gaseous exchange!0.024053182288869!6915$GO:0016894!endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters!0.024053182288869!6037$GO:0006401!RNA catabolic process!0.0337842027341225!6037$GO:0015103!inorganic anion transmembrane transporter activity!0.0452733688192364!115019$GO:0004521!endoribonuclease activity!0.0452733688192364!6037
 
|gostat_on_coexpression_clusters=GO:0004961!thromboxane A2 receptor activity!0.00883080183680678!6915$GO:0004960!thromboxane receptor activity!0.024053182288869!6915$GO:0015116!sulfate transmembrane transporter activity!0.024053182288869!115019$GO:0008271!secondary active sulfate transmembrane transporter activity!0.024053182288869!115019$GO:0004522!pancreatic ribonuclease activity!0.024053182288869!6037$GO:0004953!icosanoid receptor activity!0.024053182288869!6915$GO:0004954!prostanoid receptor activity!0.024053182288869!6915$GO:0008272!sulfate transport!0.024053182288869!115019$GO:0016892!endoribonuclease activity, producing 3'-phosphomonoesters!0.024053182288869!6037$GO:0007585!respiratory gaseous exchange!0.024053182288869!6915$GO:0016894!endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters!0.024053182288869!6037$GO:0006401!RNA catabolic process!0.0337842027341225!6037$GO:0015103!inorganic anion transmembrane transporter activity!0.0452733688192364!115019$GO:0004521!endoribonuclease activity!0.0452733688192364!6037

Revision as of 06:53, 12 September 2012


Full id: C302_acute_peripheral_Neutrophils_NK_myelodysplastic_CD34_carcinoid



Phase1 CAGE Peaks

Hg19::chr10:134259182..134259198,+p@chr10:134259182..134259198
+
Hg19::chr10:22603976..22603984,-p@chr10:22603976..22603984
-
Hg19::chr11:123351501..123351547,+p@chr11:123351501..123351547
+
Hg19::chr12:125686755..125686767,+p@chr12:125686755..125686767
+
Hg19::chr12:58230871..58230881,+p1@ENST00000549683
Hg19::chr12:9886936..9886942,-p@chr12:9886936..9886942
-
Hg19::chr12:9891753..9891758,-p@chr12:9891753..9891758
-
Hg19::chr13:52303329..52303347,-p@chr13:52303329..52303347
-
Hg19::chr14:21359558..21359580,+p1@RNASE3
Hg19::chr14:21424030..21424062,+p@chr14:21424030..21424062
+
Hg19::chr14:21424359..21424370,+p@chr14:21424359..21424370
+
Hg19::chr15:41794867..41794880,+p@chr15:41794867..41794880
+
Hg19::chr15:57592859..57592869,+p5@LOC283663
Hg19::chr19:29480252..29480261,-p@chr19:29480252..29480261
-
Hg19::chr19:3600549..3600592,-p5@TBXA2R
Hg19::chr1:149157851..149157876,-p@chr1:149157851..149157876
-
Hg19::chr1:165506847..165506853,+p@chr1:165506847..165506853
+
Hg19::chr1:200876945..200876972,+p@chr1:200876945..200876972
+
Hg19::chr1:205899165..205899172,-p8@SLC26A9
Hg19::chr1:205899180..205899197,-p3@SLC26A9
Hg19::chr2:135160470..135160480,+p@chr2:135160470..135160480
+
Hg19::chr3:101504030..101504047,+p12@FAM55C
Hg19::chr3:126207297..126207316,-p@chr3:126207297..126207316
-
Hg19::chr3:32896322..32896332,+p@chr3:32896322..32896332
+
Hg19::chr5:126962527..126962529,-p@chr5:126962527..126962529
-
Hg19::chr5:448728..448747,+p@chr5:448728..448747
+
Hg19::chr5:448759..448770,+p@chr5:448759..448770
+
Hg19::chr5:78011925..78011929,-p1@ENST00000519121
Hg19::chr7:155156870..155156881,+p@chr7:155156870..155156881
+
Hg19::chr7:155156893..155156902,+p@chr7:155156893..155156902
+
Hg19::chr7:155156952..155156963,+p@chr7:155156952..155156963
+
Hg19::chr7:157464010..157464017,-p@chr7:157464010..157464017
-
Hg19::chr7:158330152..158330179,+p1@ENST00000448698
Hg19::chr7:1883150..1883186,-p@chr7:1883150..1883186
-
Hg19::chr8:141370177..141370224,-p@chr8:141370177..141370224
-
Hg19::chr8:141370243..141370257,-p@chr8:141370243..141370257
-
Hg19::chr8:141370262..141370267,-p@chr8:141370262..141370267
-
Hg19::chr8:141370284..141370289,-p@chr8:141370284..141370289
-
Hg19::chrX:64818643..64818666,+p@chrX:64818643..64818666
+
Hg19::chrX:7700640..7700651,+p@chrX:7700640..7700651
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004961thromboxane A2 receptor activity0.00883080183680678
GO:0004960thromboxane receptor activity0.024053182288869
GO:0015116sulfate transmembrane transporter activity0.024053182288869
GO:0008271secondary active sulfate transmembrane transporter activity0.024053182288869
GO:0004522pancreatic ribonuclease activity0.024053182288869
GO:0004953icosanoid receptor activity0.024053182288869
GO:0004954prostanoid receptor activity0.024053182288869
GO:0008272sulfate transport0.024053182288869
GO:0016892endoribonuclease activity, producing 3'-phosphomonoesters0.024053182288869
GO:0007585respiratory gaseous exchange0.024053182288869
GO:0016894endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters0.024053182288869
GO:0006401RNA catabolic process0.0337842027341225
GO:0015103inorganic anion transmembrane transporter activity0.0452733688192364
GO:0004521endoribonuclease activity0.0452733688192364



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen
hematopoietic stem cell1.94e-51172
angioblastic mesenchymal cell1.94e-51172
hematopoietic oligopotent progenitor cell3.85e-48165
hematopoietic multipotent progenitor cell3.85e-48165
hematopoietic cell6.56e-47182
leukocyte6.06e-38140
myeloid cell8.17e-35112
common myeloid progenitor8.17e-35112
hematopoietic lineage restricted progenitor cell1.12e-30124
nongranular leukocyte8.44e-30119
myeloid leukocyte7.17e-2276
granulocyte monocyte progenitor cell7.02e-1971
myeloid lineage restricted progenitor cell1.08e-1870
macrophage dendritic cell progenitor2.02e-1765
monopoietic cell5.83e-1763
monocyte5.83e-1763
monoblast5.83e-1763
promonocyte5.83e-1763
CD14-positive, CD16-negative classical monocyte1.86e-1442
classical monocyte3.28e-1445
lymphocyte1.20e-1153
common lymphoid progenitor1.20e-1153
lymphoid lineage restricted progenitor cell2.20e-1152
mesenchymal cell1.05e-10358
connective tissue cell2.02e-10365
motile cell2.45e-08390
Uber Anatomy
Ontology termp-valuen
hematopoietic system3.86e-29102
blood island3.86e-29102
hemolymphoid system4.73e-25112
bone marrow7.79e-2180
bone element2.46e-1986
immune system6.02e-16115
skeletal element7.16e-16101
skeletal system7.16e-16101
connective tissue4.28e-11375
Disease
Ontology termp-valuen
hematologic cancer3.59e-1851
immune system cancer3.59e-1851
leukemia2.94e-1539
myeloid leukemia4.88e-1231


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data