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Coexpression cluster:C302: Difference between revisions

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|gostat_on_coexpression_clusters=GO:0004961!thromboxane A2 receptor activity!0.00883080183680678!6915$GO:0004960!thromboxane receptor activity!0.024053182288869!6915$GO:0015116!sulfate transmembrane transporter activity!0.024053182288869!115019$GO:0008271!secondary active sulfate transmembrane transporter activity!0.024053182288869!115019$GO:0004522!pancreatic ribonuclease activity!0.024053182288869!6037$GO:0004953!icosanoid receptor activity!0.024053182288869!6915$GO:0004954!prostanoid receptor activity!0.024053182288869!6915$GO:0008272!sulfate transport!0.024053182288869!115019$GO:0016892!endoribonuclease activity, producing 3'-phosphomonoesters!0.024053182288869!6037$GO:0007585!respiratory gaseous exchange!0.024053182288869!6915$GO:0016894!endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters!0.024053182288869!6037$GO:0006401!RNA catabolic process!0.0337842027341225!6037$GO:0015103!inorganic anion transmembrane transporter activity!0.0452733688192364!115019$GO:0004521!endoribonuclease activity!0.0452733688192364!6037
|gostat_on_coexpression_clusters=GO:0004961!thromboxane A2 receptor activity!0.00883080183680678!6915$GO:0004960!thromboxane receptor activity!0.024053182288869!6915$GO:0015116!sulfate transmembrane transporter activity!0.024053182288869!115019$GO:0008271!secondary active sulfate transmembrane transporter activity!0.024053182288869!115019$GO:0004522!pancreatic ribonuclease activity!0.024053182288869!6037$GO:0004953!icosanoid receptor activity!0.024053182288869!6915$GO:0004954!prostanoid receptor activity!0.024053182288869!6915$GO:0008272!sulfate transport!0.024053182288869!115019$GO:0016892!endoribonuclease activity, producing 3'-phosphomonoesters!0.024053182288869!6037$GO:0007585!respiratory gaseous exchange!0.024053182288869!6915$GO:0016894!endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters!0.024053182288869!6037$GO:0006401!RNA catabolic process!0.0337842027341225!6037$GO:0015103!inorganic anion transmembrane transporter activity!0.0452733688192364!115019$GO:0004521!endoribonuclease activity!0.0452733688192364!6037
|id=C302
|id=C302
|ontology_enrichment_celltype=CL:0000037!1.94e-51!172;CL:0000566!1.94e-51!172;CL:0002032!3.85e-48!165;CL:0000837!3.85e-48!165;CL:0000988!6.56e-47!182;CL:0000738!6.06e-38!140;CL:0000763!8.17e-35!112;CL:0000049!8.17e-35!112;CL:0002031!1.12e-30!124;CL:0002087!8.44e-30!119;CL:0000766!7.17e-22!76;CL:0000557!7.02e-19!71;CL:0000839!1.08e-18!70;CL:0002009!2.02e-17!65;CL:0002194!5.83e-17!63;CL:0000576!5.83e-17!63;CL:0000040!5.83e-17!63;CL:0000559!5.83e-17!63;CL:0002057!1.86e-14!42;CL:0000860!3.28e-14!45;CL:0000542!1.20e-11!53;CL:0000051!1.20e-11!53;CL:0000838!2.20e-11!52;CL:0000134!1.05e-10!358;CL:0002320!2.02e-10!365;CL:0000219!2.45e-08!390
|ontology_enrichment_celltype=
|ontology_enrichment_disease=DOID:2531!3.59e-18!51;DOID:0060083!3.59e-18!51;DOID:1240!2.94e-15!39;DOID:8692!4.88e-12!31
|ontology_enrichment_disease=DOID:225!6.58e-50!1;DOID:74!9.18e-26!2;DOID:8692!2.73e-15!31;DOID:1287!1.29e-13!4;DOID:1240!2.38e-12!39;DOID:2531!1.17e-09!51;DOID:0060083!1.17e-09!51
|ontology_enrichment_uberon=UBERON:0002390!3.86e-29!102;UBERON:0003061!3.86e-29!102;UBERON:0002193!4.73e-25!112;UBERON:0002371!7.79e-21!80;UBERON:0001474!2.46e-19!86;UBERON:0002405!6.02e-16!115;UBERON:0004765!7.16e-16!101;UBERON:0001434!7.16e-16!101;UBERON:0002384!4.28e-11!375
|ontology_enrichment_uberon=
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984998,0.361368,0.977928,0.842039,0.415461,0.559567,0.586279,0.253907,0.784953,0.788618,0.911359,0.320859,0.998349,0.615726,0.410395,0.704826,0.529832,0.87434,0.351944,0.836816,0.939819,0.846417,0.962334,0.486565,0.989003,0.284721,0.919899,0.679863,0.503924,0.90789,0.881266,0.603033,0.912889,0.599548,0.711262,0.992842,0.989028,0.475923,0.735307,0.388348,0.566573,0.658588,0.456039,0.547449,0.847273,0.999975,0.955915,0.508224,0.406758,0.495619,0.573001,0.648965,0.730473,0.874355,0.369662,0.642165,0.43464,0.999663,0.998444,0.96185,0.478022,0.815953,0.777369,0.484828,0.952012,0.546425,0.478029,0.99015,0.567144,0.474043,0.991495,0.627145,0.85078,0.672246,0.383126,0.832982,0.473121,1,1,0.595202,0.962445,0.783031,0.605307,0.784552,0.147364,0.739058,0.953631,0.649313,0.463696,0.461072,0.253783,0.967246,0.650628,0.400866,0.295479,0.458798,0.169456,0.0812429,0.727697,0.919814,0.771976,0.846318,0.543833,0.971547,0.651345,0.988977,0.889659,0.94449,0.839357,0.760363,0.968059,0.92053,0.804912,0.643473,0.578103,0.774249,0.882882,0.999914,0.392937,0.63018,0.723448,0.56324,0.00554582,0.0238224,0.744896,0.894185,0.453398,0.943295,0.860253,0.968342,0.978971,0.0891468,0.503566,0.689078,0.903154,0.798303,0.796798,0.145291,0.922798,0.735167,0.77457,0.734138,0.867243,0.408679,0.906313,0.0606316,0.798071,0.291904,0.443522,0.361495,0.827372,0.699263,0.938421,0.677586,0.756145,0.661111,0.556564,0.996041,0.556105,0.977365,0.927186,0.962469,0.464113,0.999064,0.999997,0.387392,0.834589,0.846428,0.447023,0.852269,0.97492,0.944198,0.680211,0.916963,0.865159,0.998155,0.781793,0.862656,0.608983,0.95593,0.561719,0.511554,0.712357,0.821972,0.880853,0.71906,0.963992,0.980396,0.998041,0.220275,0.993398,0.994934,0.984017,0.988611,1,1,0.449236,0.853081,0.971349,0.988861,0.651932,0.152735,0.998451,0.990077,0.00262112,0.689703,0.213093,0.662207,0.98847,0.973286,0.909448,0.60476,0.108878,0.0309768,0.717708,0.99993,0.895623,0.999977,0.896592,0.210915,0.999945,0.880751,0.994415,1,0.985837,0.999951,0.991767,0.967844,0.999745,0.997501,0.805633,0.949383,0.013455,0.854134,0.557275,0.747535,0.066429,0.955176,0.39413,0.868851,0.999157,0.740204,0.878145,0.930617,0.907967,0.273597,0.509193,0.821736,0.922183,0.136881,0.930682,0.817511,0.999777,0.999997,0.169433,0.920225,0.760071,0.901156,0.913368,0.985785,0.89028,0.195255,1,0.999612,0.964834,0.92741,0.927057,0.915461,0.991509,0.715956,0.809028,0.551239,0.863779,0.981194,0.699052,0.339134,0.686797,0.0345459,0.377816,0.923325,0.995474,0.289095,0.76946,0.402685,0.997678,0.79744,0.788356,0.938792,0.873261,0.0126439,0.797363,0.872359,0.954329,0.682354,0.927746,0.866287,0.536091,0.0799741,0.584403,0.955445,0.709771,0.89213,0.778018,0.958677,0.0172985,0.884271,0.962074,0.717428,0.843431,0.833969,0.335956,0.538755,0.450468,0.960831,0.86632,0.711491,0.0377339,0.546724,0.991,0.907278,0.985824,0.943185,0.620941,0.956097,0.991866,0.842853,0.108614,0.339041,0.998437,0.988982,0.625893,0.781521,0.202735,0.687554,0.591382,0.730182,0.660869,0.805413,0.367069,0.36699,0.769605,0.907988,0.938027,0.630337,0.586395,0.091596,0.314016,0.90683,0.841772,0.955376,0.715933,0.737187,0.436101,0.346689,0.876552,0.752094,0.599126,0.174612,0.490683,0.780416,0.425902,0.433712,0.916104,0.992991,0.414983,0.566009,0.0614325,0.523612,0.179119,0.357126,0.729122,0.828975,0.928939,0.967638,0.987175,0.696566,0.846489,0.955643,0.52507,0.965016,0.238301,0.955718,0.00361839,0.798141,0.877502,0.269838,0.682482,0.456183,0.914931,0.407501,0.598202,0.510711,0.462929,0.786189,0.801147,0.354101,0.656182,0.818666,0.16293,0.78363,0.559036,0.834379,0.8998,0.843612,0.944745,0.829399,0.981832,0.543141,0.929762,0.205319,0.756882,0.88678,0.411594,0.526345,0.7543,0.934979,0.264625,0.907513,0.911748,0.952089,0.959546,0.599233,0.0563296,0.942708,0.336003,0.227958,0.439703,0.889755,0.464648,0.949331,0.596059,0.946453,0.499053,0.896556,0.558639,0.905456,0.433041,0.919437,0.0169768,0.743203,0.950753,0.871536,0.640122,0.962425,0.681527,0.950694,0.777986,0.520306,0.521443,0.887483,0.661433,0.425551,0.521186,0.994146,0.575434,0.389783,0.148038,0.869079,0.531109,0.67711,0.747641,0.586844,0.823327,0.585221,0.770803,0.599498,0.652694,0.84078,0.785913,0.452011,0.603065,0.713996,0.392964,0.855319,0.952578,0.947091,0.988941,0.8182,0.60413,0.580425,0.0477591,0.949055,0.263554,0.991126,0.0453072,0.926324,0.936238,0.983336,0.847996,0.677174,0.954024,0.568376,0.939312,0.972602,0.967023,0.806255,0.838898,0.850696,0.80468,0.32856,0.313847,0.816287,0.988201,0.978398,0.691241,0.851537,0.73018,0.043715,0.444159,0.0143542,0.739159,0.698184,0.746141,0.918851,0.900383,0.923239,0.626018,0.790709,0.758273,0.247755,0.924231,0.89787,0.628299,0.899669,0.953804,0.997472
}}
}}

Revision as of 14:43, 19 October 2012


Full id: C302_acute_peripheral_Neutrophils_NK_myelodysplastic_CD34_carcinoid



Phase1 CAGE Peaks

Hg19::chr10:134259182..134259198,+p@chr10:134259182..134259198
+
Hg19::chr10:22603976..22603984,-p@chr10:22603976..22603984
-
Hg19::chr11:123351501..123351547,+p@chr11:123351501..123351547
+
Hg19::chr12:125686755..125686767,+p@chr12:125686755..125686767
+
Hg19::chr12:58230871..58230881,+p1@ENST00000549683
Hg19::chr12:9886936..9886942,-p@chr12:9886936..9886942
-
Hg19::chr12:9891753..9891758,-p@chr12:9891753..9891758
-
Hg19::chr13:52303329..52303347,-p@chr13:52303329..52303347
-
Hg19::chr14:21359558..21359580,+p1@RNASE3
Hg19::chr14:21424030..21424062,+p@chr14:21424030..21424062
+
Hg19::chr14:21424359..21424370,+p@chr14:21424359..21424370
+
Hg19::chr15:41794867..41794880,+p@chr15:41794867..41794880
+
Hg19::chr15:57592859..57592869,+p5@LOC283663
Hg19::chr19:29480252..29480261,-p@chr19:29480252..29480261
-
Hg19::chr19:3600549..3600592,-p5@TBXA2R
Hg19::chr1:149157851..149157876,-p@chr1:149157851..149157876
-
Hg19::chr1:165506847..165506853,+p@chr1:165506847..165506853
+
Hg19::chr1:200876945..200876972,+p@chr1:200876945..200876972
+
Hg19::chr1:205899165..205899172,-p8@SLC26A9
Hg19::chr1:205899180..205899197,-p3@SLC26A9
Hg19::chr2:135160470..135160480,+p@chr2:135160470..135160480
+
Hg19::chr3:101504030..101504047,+p12@FAM55C
Hg19::chr3:126207297..126207316,-p@chr3:126207297..126207316
-
Hg19::chr3:32896322..32896332,+p@chr3:32896322..32896332
+
Hg19::chr5:126962527..126962529,-p@chr5:126962527..126962529
-
Hg19::chr5:448728..448747,+p@chr5:448728..448747
+
Hg19::chr5:448759..448770,+p@chr5:448759..448770
+
Hg19::chr5:78011925..78011929,-p1@ENST00000519121
Hg19::chr7:155156870..155156881,+p@chr7:155156870..155156881
+
Hg19::chr7:155156893..155156902,+p@chr7:155156893..155156902
+
Hg19::chr7:155156952..155156963,+p@chr7:155156952..155156963
+
Hg19::chr7:157464010..157464017,-p@chr7:157464010..157464017
-
Hg19::chr7:158330152..158330179,+p1@ENST00000448698
Hg19::chr7:1883150..1883186,-p@chr7:1883150..1883186
-
Hg19::chr8:141370177..141370224,-p@chr8:141370177..141370224
-
Hg19::chr8:141370243..141370257,-p@chr8:141370243..141370257
-
Hg19::chr8:141370262..141370267,-p@chr8:141370262..141370267
-
Hg19::chr8:141370284..141370289,-p@chr8:141370284..141370289
-
Hg19::chrX:64818643..64818666,+p@chrX:64818643..64818666
+
Hg19::chrX:7700640..7700651,+p@chrX:7700640..7700651
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004961thromboxane A2 receptor activity0.00883080183680678
GO:0004960thromboxane receptor activity0.024053182288869
GO:0015116sulfate transmembrane transporter activity0.024053182288869
GO:0008271secondary active sulfate transmembrane transporter activity0.024053182288869
GO:0004522pancreatic ribonuclease activity0.024053182288869
GO:0004953icosanoid receptor activity0.024053182288869
GO:0004954prostanoid receptor activity0.024053182288869
GO:0008272sulfate transport0.024053182288869
GO:0016892endoribonuclease activity, producing 3'-phosphomonoesters0.024053182288869
GO:0007585respiratory gaseous exchange0.024053182288869
GO:0016894endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters0.024053182288869
GO:0006401RNA catabolic process0.0337842027341225
GO:0015103inorganic anion transmembrane transporter activity0.0452733688192364
GO:0004521endoribonuclease activity0.0452733688192364



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br><br>disease_data<br>


Disease
Ontology termp-valuen
syndrome6.58e-501
hematopoietic system disease9.18e-262
myeloid leukemia2.73e-1531
cardiovascular system disease1.29e-134
leukemia2.38e-1239
hematologic cancer1.17e-0951
immune system cancer1.17e-0951


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data