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|full_id=C3745_Alveolar_Renal_Placental_Amniotic_amniotic_choriocarcinoma_pancreatic
|full_id=C3745_Alveolar_Renal_Placental_Amniotic_amniotic_choriocarcinoma_pancreatic
|id=C3745
|id=C3745
|ontology_enrichment_celltype=CL:0000066!7.61e-19!254;CL:0002076!3.06e-09!43;CL:0002321!1.44e-07!248;CL:0000220!3.09e-07!246
|ontology_enrichment_disease=DOID:305!7.92e-08!106
|ontology_enrichment_uberon=UBERON:0000475!1.59e-22!365;UBERON:0000481!8.75e-22!347;UBERON:0000468!1.64e-18!659;UBERON:0004119!8.65e-17!169;UBERON:0000925!8.65e-17!169;UBERON:0006595!8.65e-17!169;UBERON:0000064!1.67e-16!219;UBERON:0003104!3.28e-14!238;UBERON:0009142!3.28e-14!238;UBERON:0002100!6.10e-14!216;UBERON:0000483!1.90e-13!309;UBERON:0000467!1.94e-13!625;UBERON:0000480!3.72e-13!626;UBERON:0000119!6.24e-13!312;UBERON:0000922!1.10e-12!612;UBERON:0000062!2.85e-12!511;UBERON:0001007!1.36e-11!155;UBERON:0001555!1.36e-11!155;UBERON:0007026!1.36e-11!155;UBERON:0002050!4.12e-11!605;UBERON:0005423!4.12e-11!605;UBERON:0000923!6.83e-11!604;UBERON:0005291!6.83e-11!604;UBERON:0006598!6.83e-11!604;UBERON:0002532!6.83e-11!604;UBERON:0000464!9.23e-10!104;UBERON:0000477!1.56e-09!286;UBERON:0004111!1.69e-09!241;UBERON:0001004!2.46e-09!72;UBERON:0004121!3.05e-09!169;UBERON:0009569!3.48e-09!113;UBERON:0000077!4.48e-09!130;UBERON:0005631!1.91e-08!14;UBERON:0000158!1.91e-08!14;UBERON:0000466!2.74e-08!126;UBERON:0000924!3.64e-08!173;UBERON:0006601!3.64e-08!173;UBERON:0004921!5.70e-08!129;UBERON:0004185!5.70e-08!129;UBERON:0000915!5.91e-08!52;UBERON:0001008!1.22e-07!45;UBERON:0000033!1.67e-07!123;UBERON:0005157!2.00e-07!51;UBERON:0005177!2.05e-07!107;UBERON:0006554!2.23e-07!44;UBERON:0005911!3.47e-07!82;UBERON:0005256!3.76e-07!143;UBERON:0000153!4.62e-07!129;UBERON:0007811!4.62e-07!129;UBERON:0005156!5.19e-07!59;UBERON:0000990!5.19e-07!59;UBERON:0000065!5.34e-07!53;UBERON:0003064!6.28e-07!37
}}
}}

Revision as of 14:40, 21 May 2012


Full id: C3745_Alveolar_Renal_Placental_Amniotic_amniotic_choriocarcinoma_pancreatic



Phase1 CAGE Peaks

Hg19::chr19:10736157..10736169,+p4@SLC44A2
Hg19::chr19:10736183..10736247,+p2@SLC44A2
Hg19::chr19:10736263..10736275,+p3@SLC44A2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen
epithelial cell7.61e-19254
endo-epithelial cell3.06e-0943
embryonic cell1.44e-07248
Uber Anatomy
Ontology termp-valuen
organism subdivision1.59e-22365
multi-tissue structure8.75e-22347
multi-cellular organism1.64e-18659
endoderm-derived structure8.65e-17169
endoderm8.65e-17169
presumptive endoderm8.65e-17169
organ part1.67e-16219
mesenchyme3.28e-14238
entire embryonic mesenchyme3.28e-14238
trunk6.10e-14216
epithelium1.90e-13309
anatomical system1.94e-13625
anatomical group3.72e-13626
cell layer6.24e-13312
embryo1.10e-12612
organ2.85e-12511
digestive system1.36e-11155
digestive tract1.36e-11155
primitive gut1.36e-11155
embryonic structure4.12e-11605
developing anatomical structure4.12e-11605
germ layer6.83e-11604
embryonic tissue6.83e-11604
presumptive structure6.83e-11604
epiblast (generic)6.83e-11604
anatomical space9.23e-10104
anatomical cluster1.56e-09286
anatomical conduit1.69e-09241
respiratory system2.46e-0972
ectoderm-derived structure3.05e-09169
subdivision of trunk3.48e-09113
mixed endoderm/mesoderm-derived structure4.48e-09130
extraembryonic membrane1.91e-0814
membranous layer1.91e-0814
immaterial anatomical entity2.74e-08126
ectoderm3.64e-08173
presumptive ectoderm3.64e-08173
subdivision of digestive tract5.70e-08129
endodermal part of digestive tract5.70e-08129
thoracic segment of trunk5.91e-0852
renal system1.22e-0745
head1.67e-07123
epithelial fold2.00e-0751
trunk region element2.05e-07107
urinary system structure2.23e-0744
endo-epithelium3.47e-0782
trunk mesenchyme3.76e-07143
anterior region of body4.62e-07129
craniocervical region4.62e-07129
reproductive structure5.19e-0759
reproductive system5.19e-0759
respiratory tract5.34e-0753
intermediate mesoderm6.28e-0737
Disease
Ontology termp-valuen
carcinoma7.92e-08106


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.