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{{Coexpression_clusters
{{Coexpression_clusters
|full_id=C392_Monocytederived_CD14_Macrophage_CD14CD16_Dendritic_Eosinophils_migratory
|full_id=C392_Monocytederived_CD14_Macrophage_CD14CD16_Dendritic_Eosinophils_migratory
|gostat_on_coexpression_clusters=GO:0042330!taxis!0.00405379739799262!1230;719;58191$GO:0006935!chemotaxis!0.00405379739799262!1230;719;58191$GO:0007626!locomotory behavior!0.00433475631325112!1230;719;58191$GO:0005764!lysosome!0.00433475631325112!427;57192;10437$GO:0000323!lytic vacuole!0.00433475631325112!427;57192;10437$GO:0042221!response to chemical stimulus!0.00433475631325112!1230;719;58191;427$GO:0005773!vacuole!0.0048306998448887!427;57192;10437$GO:0007610!behavior!0.00837779738250679!1230;719;58191$GO:0051480!cytosolic calcium ion homeostasis!0.00912516189803368!1230;719$GO:0007204!elevation of cytosolic calcium ion concentration!0.00912516189803368!1230;719$GO:0004943!C3a anaphylatoxin receptor activity!0.00912516189803368!719$GO:0004876!complement component C3a receptor activity!0.00912516189803368!719$GO:0006874!cellular calcium ion homeostasis!0.0193159095894078!1230;719$GO:0055074!calcium ion homeostasis!0.0193159095894078!1230;719$GO:0006875!cellular metal ion homeostasis!0.0193159095894078!1230;719$GO:0055065!metal ion homeostasis!0.0193159095894078!1230;719$GO:0004875!complement receptor activity!0.0193159095894078!719$GO:0004942!anaphylatoxin receptor activity!0.0225218536178917!719$GO:0048247!lymphocyte chemotaxis!0.0225218536178917!58191$GO:0001653!peptide receptor activity!0.0225218536178917!1230;719$GO:0008528!peptide receptor activity, G-protein coupled!0.0225218536178917!1230;719$GO:0009605!response to external stimulus!0.0279409002264544!1230;719;58191$GO:0001848!complement binding!0.02853630822038!719$GO:0030005!cellular di-, tri-valent inorganic cation homeostasis!0.0287048152723536!1230;719$GO:0055066!di-, tri-valent inorganic cation homeostasis!0.0287048152723536!1230;719$GO:0030003!cellular cation homeostasis!0.0325569677870366!1230;719$GO:0055080!cation homeostasis!0.0325569677870366!1230;719$GO:0042277!peptide binding!0.0329217591962625!1230;719$GO:0016021!integral to membrane!0.0329326172035117!84868;1230;719;10184;219855;58191;3903;57192$GO:0031224!intrinsic to membrane!0.0329326172035117!84868;1230;719;10184;219855;58191;3903;57192$GO:0055082!cellular chemical homeostasis!0.0343440629744898!1230;719$GO:0006873!cellular ion homeostasis!0.0343440629744898!1230;719$GO:0005041!low-density lipoprotein receptor activity!0.0343440629744898!58191$GO:0030228!lipoprotein receptor activity!0.0343440629744898!58191$GO:0004185!serine carboxypeptidase activity!0.0343440629744898!59342$GO:0017040!ceramidase activity!0.0364180192480767!427$GO:0050801!ion homeostasis!0.0404833389821219!1230;719$GO:0006954!inflammatory response!0.0465522445284474!1230;719$GO:0030169!low-density lipoprotein binding!0.0475041394165519!58191$GO:0048878!chemical homeostasis!0.0475041394165519!1230;719
|id=C392
|id=C392
}}
}}

Revision as of 17:39, 18 May 2012


Full id: C392_Monocytederived_CD14_Macrophage_CD14CD16_Dendritic_Eosinophils_migratory



Phase1 CAGE Peaks

Hg19::chr11:124932955..124932970,+p3@SLC37A2
Hg19::chr12:8218926..8218980,-p1@C3AR1
Hg19::chr13:44453688..44453795,+p1@LACC1
Hg19::chr13:50018402..50018469,+p1@SETDB2
Hg19::chr17:4642690..4642701,-p9@CXCL16
Hg19::chr17:55055472..55055522,+p1@SCPEP1
Hg19::chr18:74824549..74824569,+p1@AK097116
Hg19::chr19:18284561..18284667,+p1@IFI30
Hg19::chr19:54876531..54876549,-p1@LAIR1
Hg19::chr19:7587555..7587570,+p2@MCOLN1
Hg19::chr1:17944806..17944819,+p10@ARHGEF10L
Hg19::chr1:17944832..17944849,+p2@ARHGEF10L
Hg19::chr1:228870893..228870910,+p3@RHOU
Hg19::chr3:46249843..46249846,-p6@CCR1
Hg19::chr3:46249859..46249874,-p4@CCR1
Hg19::chr3:46249878..46249905,-p2@CCR1
Hg19::chr3:46412794..46412814,-p@chr3:46412794..46412814
-
Hg19::chr3:46412829..46412861,-p@chr3:46412829..46412861
-
Hg19::chr5:156536036..156536065,-p2@HAVCR2
Hg19::chr5:156536071..156536082,-p9@HAVCR2
Hg19::chr5:156536090..156536106,-p8@HAVCR2
Hg19::chr5:180257951..180257966,+p1@ENST00000501855
Hg19::chr5:180257974..180258065,+p1@ENST00000502162
p1@ENST00000508309
p1@ENST00000509921
Hg19::chr5:77806227..77806251,-p6@LHFPL2
Hg19::chr5:77806360..77806396,-p9@LHFPL2
Hg19::chr8:17941575..17941642,-p1@ASAH1
Hg19::chr9:115983665..115983682,-p5@FKBP15


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0042330taxis0.00405379739799262
GO:0006935chemotaxis0.00405379739799262
GO:0007626locomotory behavior0.00433475631325112
GO:0005764lysosome0.00433475631325112
GO:0000323lytic vacuole0.00433475631325112
GO:0042221response to chemical stimulus0.00433475631325112
GO:0005773vacuole0.0048306998448887
GO:0007610behavior0.00837779738250679
GO:0051480cytosolic calcium ion homeostasis0.00912516189803368
GO:0007204elevation of cytosolic calcium ion concentration0.00912516189803368
GO:0004943C3a anaphylatoxin receptor activity0.00912516189803368
GO:0004876complement component C3a receptor activity0.00912516189803368
GO:0006874cellular calcium ion homeostasis0.0193159095894078
GO:0055074calcium ion homeostasis0.0193159095894078
GO:0006875cellular metal ion homeostasis0.0193159095894078
GO:0055065metal ion homeostasis0.0193159095894078
GO:0004875complement receptor activity0.0193159095894078
GO:0004942anaphylatoxin receptor activity0.0225218536178917
GO:0048247lymphocyte chemotaxis0.0225218536178917
GO:0001653peptide receptor activity0.0225218536178917
GO:0008528peptide receptor activity, G-protein coupled0.0225218536178917
GO:0009605response to external stimulus0.0279409002264544
GO:0001848complement binding0.02853630822038
GO:0030005cellular di-, tri-valent inorganic cation homeostasis0.0287048152723536
GO:0055066di-, tri-valent inorganic cation homeostasis0.0287048152723536
GO:0030003cellular cation homeostasis0.0325569677870366
GO:0055080cation homeostasis0.0325569677870366
GO:0042277peptide binding0.0329217591962625
GO:0016021integral to membrane0.0329326172035117
GO:0031224intrinsic to membrane0.0329326172035117
GO:0055082cellular chemical homeostasis0.0343440629744898
GO:0006873cellular ion homeostasis0.0343440629744898
GO:0005041low-density lipoprotein receptor activity0.0343440629744898
GO:0030228lipoprotein receptor activity0.0343440629744898
GO:0004185serine carboxypeptidase activity0.0343440629744898
GO:0017040ceramidase activity0.0364180192480767
GO:0050801ion homeostasis0.0404833389821219
GO:0006954inflammatory response0.0465522445284474
GO:0030169low-density lipoprotein binding0.0475041394165519
GO:0048878chemical homeostasis0.0475041394165519



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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