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Coexpression cluster:C4069: Difference between revisions

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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!2.09e-25!115;UBERON:0001017!3.18e-18!82;UBERON:0005743!1.47e-17!86;UBERON:0000073!6.59e-17!94;UBERON:0001016!6.59e-17!94;UBERON:0001049!1.46e-15!57;UBERON:0005068!1.46e-15!57;UBERON:0006241!1.46e-15!57;UBERON:0007135!1.46e-15!57;UBERON:0000955!1.78e-15!69;UBERON:0006238!1.78e-15!69;UBERON:0002616!4.46e-15!59;UBERON:0000477!1.36e-13!286;UBERON:0002346!2.39e-13!90;UBERON:0003075!9.03e-13!86;UBERON:0007284!9.03e-13!86;UBERON:0000468!2.30e-12!659;UBERON:0000153!6.84e-12!129;UBERON:0007811!6.84e-12!129;UBERON:0003080!1.36e-11!42;UBERON:0000033!1.68e-11!123;UBERON:0000924!1.87e-11!173;UBERON:0006601!1.87e-11!173;UBERON:0002780!3.46e-11!41;UBERON:0001890!3.46e-11!41;UBERON:0006240!3.46e-11!41;UBERON:0004121!6.60e-11!169;UBERON:0004111!6.16e-10!241;UBERON:0002050!1.09e-09!605;UBERON:0005423!1.09e-09!605;UBERON:0000922!1.42e-09!612;UBERON:0000923!2.53e-09!604;UBERON:0005291!2.53e-09!604;UBERON:0006598!2.53e-09!604;UBERON:0002532!2.53e-09!604;UBERON:0000481!4.53e-09!347;UBERON:0000467!5.39e-09!625;UBERON:0002020!6.89e-09!34;UBERON:0003528!6.89e-09!34;UBERON:0001893!7.15e-09!34;UBERON:0000480!7.74e-09!626;UBERON:0002791!1.02e-08!33;UBERON:0001869!1.05e-08!32;UBERON:0003056!2.67e-08!61;UBERON:0000956!9.61e-08!25;UBERON:0000203!9.61e-08!25;UBERON:0000025!1.09e-07!194;UBERON:0000062!7.75e-07!511
|ontology_enrichment_uberon=UBERON:0007023!2.09e-25!115;UBERON:0001017!3.18e-18!82;UBERON:0005743!1.47e-17!86;UBERON:0000073!6.59e-17!94;UBERON:0001016!6.59e-17!94;UBERON:0001049!1.46e-15!57;UBERON:0005068!1.46e-15!57;UBERON:0006241!1.46e-15!57;UBERON:0007135!1.46e-15!57;UBERON:0000955!1.78e-15!69;UBERON:0006238!1.78e-15!69;UBERON:0002616!4.46e-15!59;UBERON:0000477!1.36e-13!286;UBERON:0002346!2.39e-13!90;UBERON:0003075!9.03e-13!86;UBERON:0007284!9.03e-13!86;UBERON:0000468!2.30e-12!659;UBERON:0000153!6.84e-12!129;UBERON:0007811!6.84e-12!129;UBERON:0003080!1.36e-11!42;UBERON:0000033!1.68e-11!123;UBERON:0000924!1.87e-11!173;UBERON:0006601!1.87e-11!173;UBERON:0002780!3.46e-11!41;UBERON:0001890!3.46e-11!41;UBERON:0006240!3.46e-11!41;UBERON:0004121!6.60e-11!169;UBERON:0004111!6.16e-10!241;UBERON:0002050!1.09e-09!605;UBERON:0005423!1.09e-09!605;UBERON:0000922!1.42e-09!612;UBERON:0000923!2.53e-09!604;UBERON:0005291!2.53e-09!604;UBERON:0006598!2.53e-09!604;UBERON:0002532!2.53e-09!604;UBERON:0000481!4.53e-09!347;UBERON:0000467!5.39e-09!625;UBERON:0002020!6.89e-09!34;UBERON:0003528!6.89e-09!34;UBERON:0001893!7.15e-09!34;UBERON:0000480!7.74e-09!626;UBERON:0002791!1.02e-08!33;UBERON:0001869!1.05e-08!32;UBERON:0003056!2.67e-08!61;UBERON:0000956!9.61e-08!25;UBERON:0000203!9.61e-08!25;UBERON:0000025!1.09e-07!194;UBERON:0000062!7.75e-07!511
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}}
}}

Revision as of 19:42, 8 August 2012


Full id: C4069_medulloblastoma_uterus_cervix_ovary_trachea_heart_throat



Phase1 CAGE Peaks

Hg19::chr21:17791855..17791869,+p14@LINC00478
Hg19::chr21:17791874..17791892,+p6@LINC00478
Hg19::chr21:17791908..17791940,+p3@LINC00478


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism2.09e-25115
central nervous system3.18e-1882
regional part of nervous system6.59e-1794
nervous system6.59e-1794
neural tube1.46e-1557
neural rod1.46e-1557
future spinal cord1.46e-1557
neural keel1.46e-1557
brain1.78e-1569
future brain1.78e-1569
regional part of brain4.46e-1559
anatomical cluster1.36e-13286
neurectoderm2.39e-1390
neural plate9.03e-1386
presumptive neural plate9.03e-1386
multi-cellular organism2.30e-12659
anterior region of body6.84e-12129
craniocervical region6.84e-12129
anterior neural tube1.36e-1142
head1.68e-11123
ectoderm1.87e-11173
presumptive ectoderm1.87e-11173
regional part of forebrain3.46e-1141
forebrain3.46e-1141
future forebrain3.46e-1141
ectoderm-derived structure6.60e-11169
anatomical conduit6.16e-10241
embryonic structure1.09e-09605
developing anatomical structure1.09e-09605
embryo1.42e-09612
germ layer2.53e-09604
embryonic tissue2.53e-09604
presumptive structure2.53e-09604
epiblast (generic)2.53e-09604
multi-tissue structure4.53e-09347
anatomical system5.39e-09625
gray matter6.89e-0934
brain grey matter6.89e-0934
telencephalon7.15e-0934
anatomical group7.74e-09626
regional part of telencephalon1.02e-0833
cerebral hemisphere1.05e-0832
pre-chordal neural plate2.67e-0861
cerebral cortex9.61e-0825
pallium9.61e-0825
tube1.09e-07194
organ7.75e-07511


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.