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{{Coexpression_clusters
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|coexpression_dpi_cluster_scores_median=0.

Latest revision as of 11:25, 17 September 2013


Full id: C563_Mesenchymal_Fibroblast_Adipocyte_tenocyte_Placental_Hair_Synoviocyte



Phase1 CAGE Peaks

Hg19::chr11:66082644..66082662,-p@chr11:66082644..66082662
-
Hg19::chr11:66082821..66082867,+p@chr11:66082821..66082867
+
Hg19::chr11:66082875..66082914,-p@chr11:66082875..66082914
-
Hg19::chr11:66082877..66082889,+p@chr11:66082877..66082889
+
Hg19::chr11:66082890..66082979,+p@chr11:66082890..66082979
+
Hg19::chr11:66082918..66082935,-p@chr11:66082918..66082935
-
Hg19::chr11:66083010..66083055,-p@chr11:66083010..66083055
-
Hg19::chr11:66083107..66083156,-p4@CD248
Hg19::chr11:66083180..66083195,-p8@CD248
Hg19::chr11:66083196..66083252,-p2@CD248
Hg19::chr11:66083335..66083379,+p@chr11:66083335..66083379
+
Hg19::chr11:66083418..66083442,-p3@CD248
Hg19::chr11:66083457..66083472,-p7@CD248
Hg19::chr11:66083621..66083639,-p5@CD248
Hg19::chr11:66084059..66084071,-p12@CD248
Hg19::chr11:66084508..66084523,-p1@CD248


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
dense mesenchyme tissue4.75e-1973
somite6.31e-1971
presomitic mesoderm6.31e-1971
presumptive segmental plate6.31e-1971
dermomyotome6.31e-1971
trunk paraxial mesoderm6.31e-1971
paraxial mesoderm2.24e-1872
presumptive paraxial mesoderm2.24e-1872
multilaminar epithelium4.67e-1683
muscle tissue4.78e-1664
musculature4.78e-1664
musculature of body4.78e-1664
skeletal muscle tissue1.53e-1562
striated muscle tissue1.53e-1562
myotome1.53e-1562
epithelial vesicle2.05e-1578
integument5.81e-1346
integumental system5.81e-1346
trunk mesenchyme1.33e-11122
adipose tissue2.50e-1114
surface structure6.98e-1199
mesenchyme1.13e-10160
entire embryonic mesenchyme1.13e-10160
organ component layer1.48e-1066
skin of body8.58e-1041
connective tissue3.39e-08371
mesoderm7.42e-08315
mesoderm-derived structure7.42e-08315
presumptive mesoderm7.42e-08315
tissue1.17e-07773
organism subdivision1.80e-07264
unilaminar epithelium2.79e-07148
extraembryonic membrane8.85e-0714
membranous layer8.85e-0714


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.357653
MA0004.10.670242
MA0006.10.784773
MA0007.10.223897
MA0009.10.644692
MA0014.10.304599
MA0017.10.150184
MA0019.10.359322
MA0024.10.547222
MA0025.10.771296
MA0027.12.23171
MA0028.11.34419
MA0029.10.565022
MA0030.10.554453
MA0031.10.495474
MA0038.10.859342
MA0040.10.570428
MA0041.10.252793
MA0042.12.63912
MA0043.10.644989
MA0046.10.634468
MA0048.10.390294
MA0050.10.228625
MA0051.10.317617
MA0052.10.574006
MA0055.10.499384
MA0056.10
MA0057.10.189848
MA0058.10.968374
MA0059.10.166682
MA0060.10.0584466
MA0061.10.0461955
MA0063.10
MA0066.10.321498
MA0067.10.948938
MA0068.10.0313753
MA0069.10.630852
MA0070.10.620368
MA0071.10.289163
MA0072.10.616162
MA0073.10.000310801
MA0074.10.850035
MA0076.11.01424
MA0077.10.608956
MA0078.10.402443
MA0081.10.166796
MA0083.10.651755
MA0084.11.13204
MA0087.10.613875
MA0088.11.89884
MA0089.10
MA0090.10.189305
MA0091.10.240316
MA0092.10.607109
MA0093.11.29113
MA0095.10
MA0098.10
MA0100.11.59075
MA0101.10.128426
MA0103.10.377626
MA0105.10.0129929
MA0106.10.355999
MA0107.10.0842574
MA0108.20.492699
MA0109.10
MA0111.10.578093
MA0113.10.370073
MA0114.10.278245
MA0115.10.874839
MA0116.15.70333
MA0117.10.680135
MA0119.10.471628
MA0122.10.70466
MA0124.10.834787
MA0125.10.75419
MA0130.10
MA0131.10.418384
MA0132.10
MA0133.10
MA0135.10.673296
MA0136.10.327047
MA0139.11.01536
MA0140.10.286995
MA0141.10.959654
MA0142.10.4668
MA0143.10.370225
MA0144.11.39182
MA0145.10.650967
MA0146.11.16153
MA0147.10.0881384
MA0148.10.257816
MA0149.10.279141
MA0062.20.382208
MA0035.20.286421
MA0039.20.00447383
MA0138.20.403517
MA0002.21.16356
MA0137.20.138998
MA0104.20.0580852
MA0047.20.345656
MA0112.20.612164
MA0065.22.08936
MA0150.10.185024
MA0151.10
MA0152.10.292357
MA0153.10.738108
MA0154.11.95784
MA0155.10.576832
MA0156.10.140505
MA0157.10.442323
MA0158.10
MA0159.12.10763
MA0160.10.26995
MA0161.10
MA0162.10.311763
MA0163.14.42309
MA0164.10.380804
MA0080.20.126365
MA0018.20.357181
MA0099.20.292649
MA0079.20.0101213
MA0102.21.16862
MA0258.10.0689091
MA0259.10.0929051
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.