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{{Coexpression_clusters
{{Coexpression_clusters
|full_id=C685_Alveolar_Mesenchymal_Renal_Smooth_Hepatic_Fibroblast_Keratocytes
|full_id=C685_Alveolar_Mesenchymal_Renal_Smooth_Hepatic_Fibroblast_Keratocytes
|gostat_on_coexpression_clusters=GO:0031974!membrane-enclosed lumen!0.000193512463740142!6150;79760;26517;51253;7329$GO:0043233!organelle lumen!0.000193512463740142!6150;79760;26517;51253;7329$GO:0000313!organellar ribosome!0.00299085559287461!6150;51253$GO:0005761!mitochondrial ribosome!0.00299085559287461!6150;51253$GO:0005739!mitochondrion!0.00299085559287461!6150;8192;26517;51253$GO:0030529!ribonucleoprotein complex!0.00411426777240149!6150;79760;51253;6142$GO:0044446!intracellular organelle part!0.00435327555541477!6150;79760;26517;51253;7329;6142$GO:0044422!organelle part!0.00435327555541477!6150;79760;26517;51253;7329;6142$GO:0043398!HLH domain binding!0.00526904509596138!7329$GO:0015934!large ribosomal subunit!0.00578115676195091!6150;6142$GO:0016604!nuclear body!0.00578115676195091!79760;7329$GO:0044429!mitochondrial part!0.00595076123775477!6150;26517;51253$GO:0043229!intracellular organelle!0.00840756935025863!6150;79760;8192;26517;51253;7329;6142;5425$GO:0043226!organelle!0.00840756935025863!6150;79760;8192;26517;51253;7329;6142;5425$GO:0008462!endopeptidase Clp activity!0.00948204782553061!8192$GO:0003735!structural constituent of ribosome!0.0100779420613185!6150;51253;6142$GO:0031980!mitochondrial lumen!0.0100779420613185!6150;51253$GO:0005759!mitochondrial matrix!0.0100779420613185!6150;51253$GO:0005840!ribosome!0.0109967187094474!6150;51253;6142$GO:0033279!ribosomal subunit!0.0123026770219084!6150;6142$GO:0042719!mitochondrial intermembrane space protein transporter complex!0.0123026770219084!26517$GO:0045039!protein import into mitochondrial inner membrane!0.0123026770219084!26517$GO:0032991!macromolecular complex!0.0123026770219084!6150;79760;26517;51253;6142$GO:0043231!intracellular membrane-bound organelle!0.0123026770219084!6150;79760;8192;26517;51253;7329;5425$GO:0043227!membrane-bound organelle!0.0123026770219084!6150;79760;8192;26517;51253;7329;5425$GO:0007007!inner mitochondrial membrane organization and biogenesis!0.0145791802178139!26517$GO:0000387!spliceosomal snRNP biogenesis!0.0157922524412481!79760$GO:0044424!intracellular part!0.0170194352354491!6150;79760;8192;26517;51253;7329;6142;5425$GO:0006412!translation!0.0197456222733237!6150;51253;6142$GO:0000795!synaptonemal complex!0.0197456222733237!7329$GO:0043681!protein import into mitochondrion!0.0197456222733237!26517$GO:0044444!cytoplasmic part!0.0197456222733237!6150;8192;26517;51253;6142$GO:0000315!organellar large ribosomal subunit!0.0202899870466734!6150$GO:0005762!mitochondrial large ribosomal subunit!0.0202899870466734!6150$GO:0005744!mitochondrial inner membrane presequence translocase complex!0.0202899870466734!26517$GO:0016605!PML body!0.0210389911498501!7329$GO:0043232!intracellular non-membrane-bound organelle!0.0227072814930335!6150;51253;7329;6142$GO:0043228!non-membrane-bound organelle!0.0227072814930335!6150;51253;7329;6142$GO:0005737!cytoplasm!0.0235427243499324!6150;79760;8192;26517;51253;6142$GO:0007006!mitochondrial membrane organization and biogenesis!0.0236577228278529!26517$GO:0006626!protein targeting to mitochondrion!0.0253827994317314!26517$GO:0044451!nucleoplasm part!0.02547497433364!79760;7329$GO:0009059!macromolecule biosynthetic process!0.0276297379577305!6150;51253;6142$GO:0005758!mitochondrial intermembrane space!0.029801120846867!26517$GO:0043170!macromolecule metabolic process!0.029801120846867!6150;79760;8192;51253;7329;6142;5425$GO:0005654!nucleoplasm!0.0303935112857104!79760;7329$GO:0031970!organelle envelope lumen!0.0305183546678942!26517$GO:0000794!condensed nuclear chromosome!0.0305183546678942!7329$GO:0044267!cellular protein metabolic process!0.0307394584809551!6150;8192;51253;7329;6142$GO:0044260!cellular macromolecule metabolic process!0.0318604052842707!6150;8192;51253;7329;6142$GO:0005842!cytosolic large ribosomal subunit (sensu Eukaryota)!0.0356935228895277!6142$GO:0019538!protein metabolic process!0.0356935228895277!6150;8192;51253;7329;6142$GO:0044249!cellular biosynthetic process!0.0405523371864651!6150;51253;6142$GO:0006839!mitochondrial transport!0.0413585107437134!26517$GO:0003887!DNA-directed DNA polymerase activity!0.0413585107437134!5425$GO:0005622!intracellular!0.0413585107437134!6150;79760;8192;26517;51253;7329;6142;5425$GO:0008430!selenium binding!0.0413585107437134!280636$GO:0031981!nuclear lumen!0.0415450125925671!79760;7329$GO:0000793!condensed chromosome!0.0415450125925671!7329$GO:0007059!chromosome segregation!0.0463138328989554!7329$GO:0044237!cellular metabolic process!0.0482158782953958!6150;79760;8192;51253;7329;6142;5425$GO:0044454!nuclear chromosome part!0.0498887043556976!7329$GO:0065002!intracellular protein transport across a membrane!0.0498887043556976!26517$GO:0000398!nuclear mRNA splicing, via spliceosome!0.0498887043556976!79760$GO:0000375!RNA splicing, via transesterification reactions!0.0498887043556976!79760$GO:0000377!RNA splicing, via transesterification reactions with bulged adenosine as nucleophile!0.0498887043556976!79760
|id=C685
|id=C685
}}
}}

Revision as of 17:41, 18 May 2012


Full id: C685_Alveolar_Mesenchymal_Renal_Smooth_Hepatic_Fibroblast_Keratocytes



Phase1 CAGE Peaks

Hg19::chr11:1968548..1968589,+p1@MRPL23
Hg19::chr11:57508973..57509018,+p3@C11orf31
Hg19::chr16:1359622..1359697,+p1@UBE2I
Hg19::chr19:13885252..13885293,+p1@C19orf53
Hg19::chr19:17970677..17970686,+p2@RPL18A
Hg19::chr19:18043810..18043835,+p1@CCDC124
Hg19::chr19:2427539..2427591,-p1@TIMM13
Hg19::chr19:45582497..45582551,+p1@GEMIN7
Hg19::chr19:6361517..6361640,+p1@CLPP
Hg19::chr1:54665832..54665877,+p1@MRPL37
Hg19::chr3:49059510..49059579,+p1@NDUFAF3
Hg19::chr7:44163126..44163155,-p1@POLD2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0031974membrane-enclosed lumen0.000193512463740142
GO:0043233organelle lumen0.000193512463740142
GO:0000313organellar ribosome0.00299085559287461
GO:0005761mitochondrial ribosome0.00299085559287461
GO:0005739mitochondrion0.00299085559287461
GO:0030529ribonucleoprotein complex0.00411426777240149
GO:0044446intracellular organelle part0.00435327555541477
GO:0044422organelle part0.00435327555541477
GO:0043398HLH domain binding0.00526904509596138
GO:0015934large ribosomal subunit0.00578115676195091
GO:0016604nuclear body0.00578115676195091
GO:0044429mitochondrial part0.00595076123775477
GO:0043229intracellular organelle0.00840756935025863
GO:0043226organelle0.00840756935025863
GO:0008462endopeptidase Clp activity0.00948204782553061
GO:0003735structural constituent of ribosome0.0100779420613185
GO:0031980mitochondrial lumen0.0100779420613185
GO:0005759mitochondrial matrix0.0100779420613185
GO:0005840ribosome0.0109967187094474
GO:0033279ribosomal subunit0.0123026770219084
GO:0042719mitochondrial intermembrane space protein transporter complex0.0123026770219084
GO:0045039protein import into mitochondrial inner membrane0.0123026770219084
GO:0032991macromolecular complex0.0123026770219084
GO:0043231intracellular membrane-bound organelle0.0123026770219084
GO:0043227membrane-bound organelle0.0123026770219084
GO:0007007inner mitochondrial membrane organization and biogenesis0.0145791802178139
GO:0000387spliceosomal snRNP biogenesis0.0157922524412481
GO:0044424intracellular part0.0170194352354491
GO:0006412translation0.0197456222733237
GO:0000795synaptonemal complex0.0197456222733237
GO:0043681protein import into mitochondrion0.0197456222733237
GO:0044444cytoplasmic part0.0197456222733237
GO:0000315organellar large ribosomal subunit0.0202899870466734
GO:0005762mitochondrial large ribosomal subunit0.0202899870466734
GO:0005744mitochondrial inner membrane presequence translocase complex0.0202899870466734
GO:0016605PML body0.0210389911498501
GO:0043232intracellular non-membrane-bound organelle0.0227072814930335
GO:0043228non-membrane-bound organelle0.0227072814930335
GO:0005737cytoplasm0.0235427243499324
GO:0007006mitochondrial membrane organization and biogenesis0.0236577228278529
GO:0006626protein targeting to mitochondrion0.0253827994317314
GO:0044451nucleoplasm part0.02547497433364
GO:0009059macromolecule biosynthetic process0.0276297379577305
GO:0005758mitochondrial intermembrane space0.029801120846867
GO:0043170macromolecule metabolic process0.029801120846867
GO:0005654nucleoplasm0.0303935112857104
GO:0031970organelle envelope lumen0.0305183546678942
GO:0000794condensed nuclear chromosome0.0305183546678942
GO:0044267cellular protein metabolic process0.0307394584809551
GO:0044260cellular macromolecule metabolic process0.0318604052842707
GO:0005842cytosolic large ribosomal subunit (sensu Eukaryota)0.0356935228895277
GO:0019538protein metabolic process0.0356935228895277
GO:0044249cellular biosynthetic process0.0405523371864651
GO:0006839mitochondrial transport0.0413585107437134
GO:0003887DNA-directed DNA polymerase activity0.0413585107437134
GO:0005622intracellular0.0413585107437134
GO:0008430selenium binding0.0413585107437134
GO:0031981nuclear lumen0.0415450125925671
GO:0000793condensed chromosome0.0415450125925671
GO:0007059chromosome segregation0.0463138328989554
GO:0044237cellular metabolic process0.0482158782953958
GO:0044454nuclear chromosome part0.0498887043556976
GO:0065002intracellular protein transport across a membrane0.0498887043556976
GO:0000398nuclear mRNA splicing, via spliceosome0.0498887043556976
GO:0000375RNA splicing, via transesterification reactions0.0498887043556976
GO:0000377RNA splicing, via transesterification reactions with bulged adenosine as nucleophile0.0498887043556976



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.