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Coexpression cluster:C766

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Full id: C766_Smooth_esophagus_throat_epididymis_Fibroblast_tonsil_Melanocyte



Phase1 CAGE Peaks

Hg19::chr1:150480576..150480591,+p1@ECM1
Hg19::chr1:150482004..150482012,+p@chr1:150482004..150482012
+
Hg19::chr1:150482135..150482170,+p@chr1:150482135..150482170
+
Hg19::chr1:150482389..150482411,+p@chr1:150482389..150482411
+
Hg19::chr1:150482416..150482432,+p@chr1:150482416..150482432
+
Hg19::chr1:150482571..150482593,+p@chr1:150482571..150482593
+
Hg19::chr1:150482598..150482612,+p@chr1:150482598..150482612
+
Hg19::chr1:150482644..150482665,-p@chr1:150482644..150482665
-
Hg19::chr1:150483436..150483468,+p@chr1:150483436..150483468
+
Hg19::chr1:150484248..150484262,+p@chr1:150484248..150484262
+
Hg19::chr1:150484855..150484880,+p@chr1:150484855..150484880
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
fibroblast4.56e-1976
skin fibroblast1.89e-1123
preadipocyte3.86e-0812
motile cell3.27e-07386
connective tissue cell4.83e-07361
Uber Anatomy
Ontology termp-valuen
surface structure1.14e-1899
integument2.44e-1646
integumental system2.44e-1646
skin of body2.81e-1441
organ component layer8.10e-1066
connective tissue3.43e-07371


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.00460185
MA0004.10.349539
MA0006.10.210781
MA0007.10.332734
MA0009.11.85742
MA0014.10.00227771
MA0017.10.24363
MA0019.10.486183
MA0024.10.688373
MA0025.10.921763
MA0027.12.39404
MA0028.10.224112
MA0029.10.707146
MA0030.10.696006
MA0031.10.633489
MA0038.10.443833
MA0040.10.712837
MA0041.10.366339
MA0042.10.337481
MA0043.10.790919
MA0046.10.779945
MA0048.10.729247
MA0050.10.338274
MA0051.10.439895
MA0052.10.716602
MA0055.10.136684
MA0056.10
MA0057.12.60171
MA0058.10.265212
MA0059.10.2641
MA0060.10.119532
MA0061.10.330174
MA0063.10
MA0066.12.93808
MA0067.11.1037
MA0068.11.4122
MA0069.10.776171
MA0070.10.765217
MA0071.10.40788
MA0072.10.760818
MA0073.10.0250803
MA0074.10.439193
MA0076.10.278993
MA0077.10.753278
MA0078.10.533387
MA0081.10.26424
MA0083.10.79797
MA0084.11.28962
MA0087.10.758426
MA0088.11.96756
MA0089.10
MA0090.11.44338
MA0091.10.927876
MA0092.10.318032
MA0093.10.213288
MA0095.10
MA0098.10
MA0100.10.456802
MA0101.10.216017
MA0103.11.11087
MA0105.10.645738
MA0106.10.482519
MA0107.10.156959
MA0108.20.630531
MA0109.10
MA0111.10.819774
MA0113.10.498009
MA0114.10.153042
MA0115.11.02805
MA0116.10.935607
MA0117.10.827487
MA0119.10.250314
MA0122.10.852927
MA0124.10.98702
MA0125.10.904129
MA0130.10
MA0131.10.550695
MA0132.10
MA0133.10
MA0135.10.820382
MA0136.10.450422
MA0139.11.06363
MA0140.11.04551
MA0141.10.726533
MA0142.10.602852
MA0143.10.498176
MA0144.10.862195
MA0145.11.62175
MA0146.10.0109959
MA0147.10.162359
MA0148.10.372124
MA0149.10.396509
MA0062.20.0969238
MA0035.20.404774
MA0039.20.0944823
MA0138.20.534556
MA0002.20.358551
MA0137.20.649788
MA0104.20.118985
MA0047.20.47109
MA0112.21.14277
MA0065.25.89664
MA0150.10.286461
MA0151.10
MA0152.10.411494
MA0153.10.887528
MA0154.10.353037
MA0155.10.462858
MA0156.10.231442
MA0157.10.576556
MA0158.10
MA0159.11.51416
MA0160.11.7766
MA0161.10
MA0162.10.00470038
MA0163.10.232847
MA0164.10.509774
MA0080.20.21336
MA0018.20.483823
MA0099.20.411824
MA0079.21.5316
MA0102.21.32663
MA0258.10.831523
MA0259.10.168926
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.