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Coexpression cluster:C766

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Full id: C766_Smooth_esophagus_throat_epididymis_Fibroblast_tonsil_Melanocyte



Phase1 CAGE Peaks

Hg19::chr1:150480576..150480591,+p1@ECM1
Hg19::chr1:150482004..150482012,+p@chr1:150482004..150482012
+
Hg19::chr1:150482135..150482170,+p@chr1:150482135..150482170
+
Hg19::chr1:150482389..150482411,+p@chr1:150482389..150482411
+
Hg19::chr1:150482416..150482432,+p@chr1:150482416..150482432
+
Hg19::chr1:150482571..150482593,+p@chr1:150482571..150482593
+
Hg19::chr1:150482598..150482612,+p@chr1:150482598..150482612
+
Hg19::chr1:150482644..150482665,-p@chr1:150482644..150482665
-
Hg19::chr1:150483436..150483468,+p@chr1:150483436..150483468
+
Hg19::chr1:150484248..150484262,+p@chr1:150484248..150484262
+
Hg19::chr1:150484855..150484880,+p@chr1:150484855..150484880
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
non-terminally differentiated cell4.90e-28180
fibroblast1.05e-2075
skin fibroblast4.78e-1023
contractile cell5.66e-0959
muscle precursor cell5.89e-0957
myoblast5.89e-0957
multi-potent skeletal muscle stem cell5.89e-0957
muscle cell2.33e-0854
smooth muscle cell3.17e-0842
smooth muscle myoblast3.17e-0842
preadipocyte8.81e-0712
Uber Anatomy
Ontology termp-valuen
surface structure2.17e-1795
organism subdivision1.03e-14365
integument3.58e-1345
integumental system3.58e-1345
somite5.84e-1383
paraxial mesoderm5.84e-1383
presomitic mesoderm5.84e-1383
presumptive segmental plate5.84e-1383
trunk paraxial mesoderm5.84e-1383
presumptive paraxial mesoderm5.84e-1383
skin of body6.54e-1240
multilaminar epithelium1.09e-1182
multi-cellular organism3.21e-11659
trunk mesenchyme8.34e-11143
dermomyotome1.33e-1070
anatomical system5.09e-10625
anatomical group9.91e-10626
organ1.38e-09511
trunk4.09e-09216
skeletal muscle tissue2.63e-0861
striated muscle tissue2.63e-0861
myotome2.63e-0861
muscle tissue3.29e-0863
musculature3.29e-0863
musculature of body3.29e-0863
multi-tissue structure1.03e-07347
organ component layer2.32e-0757
mesenchyme9.27e-07238
entire embryonic mesenchyme9.27e-07238


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.