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{{Coexpression_clusters
{{Coexpression_clusters
|full_id=C865_CD14_Neutrophils_Dendritic_placenta_cervical_epitheloid_spinal
|full_id=C865_CD14_Neutrophils_Dendritic_placenta_cervical_epitheloid_spinal
|gostat_on_coexpression_clusters=GO:0004896!hematopoietin/interferon-class (D200-domain) cytokine receptor activity!0.000158559827157831!1438;3563$GO:0004912!interleukin-3 receptor activity!0.00153064978927681!3563$GO:0019978!interleukin-3 binding!0.00153064978927681!3563$GO:0004907!interleukin receptor activity!0.0183575242003379!3563$GO:0019965!interleukin binding!0.0183575242003379!3563$GO:0004888!transmembrane receptor activity!0.0230388577844583!1438;3563$GO:0019838!growth factor binding!0.028372121655368!3563$GO:0019955!cytokine binding!0.028372121655368!3563$GO:0004872!receptor activity!0.035793698202971!1438;3563$GO:0005057!receptor signaling protein activity!0.0387720512564269!3563$GO:0004871!signal transducer activity!0.0387720512564269!1438;3563$GO:0060089!molecular transducer activity!0.0387720512564269!1438;3563
|id=C865
|id=C865
}}
}}

Revision as of 17:42, 18 May 2012


Full id: C865_CD14_Neutrophils_Dendritic_placenta_cervical_epitheloid_spinal



Phase1 CAGE Peaks

Hg19::chrX:1367460..1367489,+p@chrX:1367460..1367489
+
Hg19::chrX:1368516..1368527,-p@chrX:1368516..1368527
-
Hg19::chrX:1387700..1387717,+p1@CSF2RA
Hg19::chrX:1387721..1387738,+p2@CSF2RA
Hg19::chrX:1393727..1393755,-p@chrX:1393727..1393755
-
Hg19::chrX:1393820..1393849,-p@chrX:1393820..1393849
-
Hg19::chrX:1435460..1435487,-p@chrX:1435460..1435487
-
Hg19::chrX:1435588..1435602,-p@chrX:1435588..1435602
-
Hg19::chrX:1455478..1455515,+p2@IL3RA
Hg19::chrX:24167737..24167762,-p1@ZFX-AS1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004896hematopoietin/interferon-class (D200-domain) cytokine receptor activity0.000158559827157831
GO:0004912interleukin-3 receptor activity0.00153064978927681
GO:0019978interleukin-3 binding0.00153064978927681
GO:0004907interleukin receptor activity0.0183575242003379
GO:0019965interleukin binding0.0183575242003379
GO:0004888transmembrane receptor activity0.0230388577844583
GO:0019838growth factor binding0.028372121655368
GO:0019955cytokine binding0.028372121655368
GO:0004872receptor activity0.035793698202971
GO:0005057receptor signaling protein activity0.0387720512564269
GO:0004871signal transducer activity0.0387720512564269
GO:0060089molecular transducer activity0.0387720512564269



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.