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Coexpression cluster:C97

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Full id: C97_small_smallcell_gastrointestinal_argyrophil_putamen_duodenum_brain



Phase1 CAGE Peaks

Hg19::chr10:113748431..113748441,-p@chr10:113748431..113748441
-
Hg19::chr10:120355149..120355165,-p1@PRLHR
Hg19::chr11:129305906..129305908,+p7@BARX2
Hg19::chr11:1643561..1643566,+p@chr11:1643561..1643566
+
Hg19::chr11:18034532..18034548,-p4@SERGEF
Hg19::chr11:26618692..26618727,-p@chr11:26618692..26618727
-
Hg19::chr11:26618988..26619017,-p@chr11:26618988..26619017
-
Hg19::chr11:42912594..42912599,-p@chr11:42912594..42912599
-
Hg19::chr11:42912793..42912802,-p@chr11:42912793..42912802
-
Hg19::chr11:4665150..4665166,+p2@OR51E1
Hg19::chr11:4665183..4665193,+p3@OR51E1
Hg19::chr11:4665195..4665219,+p1@OR51E1
Hg19::chr11:4726012..4726018,+p1@MMP26
Hg19::chr11:4726112..4726125,+p2@MMP26
Hg19::chr11:4807754..4807756,+p1@OR51N1P
Hg19::chr11:5445690..5445716,+p@chr11:5445690..5445716
+
Hg19::chr11:67402354..67402359,-p@chr11:67402354..67402359
-
Hg19::chr11:67402368..67402378,-p@chr11:67402368..67402378
-
Hg19::chr11:78177190..78177210,-p@chr11:78177190..78177210
-
Hg19::chr12:127545156..127545162,+p@chr12:127545156..127545162
+
Hg19::chr12:132556644..132556656,+p@chr12:132556644..132556656
+
Hg19::chr12:51116443..51116452,+p@chr12:51116443..51116452
+
Hg19::chr12:53686428..53686432,+p@chr12:53686428..53686432
+
Hg19::chr12:53686472..53686482,+p@chr12:53686472..53686482
+
Hg19::chr12:58158560..58158567,-p@chr12:58158560..58158567
-
Hg19::chr12:76206813..76206837,-p@chr12:76206813..76206837
-
Hg19::chr13:25269076..25269105,-p@chr13:25269076..25269105
-
Hg19::chr13:25269257..25269262,+p@chr13:25269257..25269262
+
Hg19::chr14:36966895..36966899,-p@chr14:36966895..36966899
-
Hg19::chr14:57127818..57127825,+p@chr14:57127818..57127825
+
Hg19::chr14:57127856..57127863,+p@chr14:57127856..57127863
+
Hg19::chr15:62007373..62007374,-p2@ENST00000559590
Hg19::chr15:62007379..62007390,-p1@ENST00000559590
Hg19::chr16:11846874..11846885,-p14@ZC3H7A
Hg19::chr16:19396252..19396261,+p@chr16:19396252..19396261
+
Hg19::chr16:30015874..30015893,+p@chr16:30015874..30015893
+
Hg19::chr16:7354032..7354043,+p@chr16:7354032..7354043
+
Hg19::chr16:7354527..7354551,-p@chr16:7354527..7354551
-
Hg19::chr16:7354636..7354645,-p@chr16:7354636..7354645
-
Hg19::chr16:7354657..7354690,-p@chr16:7354657..7354690
-
Hg19::chr16:7428243..7428259,+p@chr16:7428243..7428259
+
Hg19::chr16:83649377..83649388,+p@chr16:83649377..83649388
+
Hg19::chr16:83649482..83649491,+p@chr16:83649482..83649491
+
Hg19::chr16:8524660..8524680,-p@chr16:8524660..8524680
-
Hg19::chr17:27308382..27308398,+p@chr17:27308382..27308398
+
Hg19::chr17:27333028..27333089,-p1@SEZ6
Hg19::chr17:27333187..27333207,-p13@SEZ6
Hg19::chr17:27333311..27333318,-p21@SEZ6
Hg19::chr17:39140393..39140399,-p3@KRT40
Hg19::chr17:39140411..39140419,-p5@KRT40
Hg19::chr17:39140424..39140431,-p4@KRT40
Hg19::chr17:39140549..39140579,-p1@KRT40
Hg19::chr17:43749913..43749923,+p@chr17:43749913..43749923
+
Hg19::chr17:78560489..78560497,+p@chr17:78560489..78560497
+
Hg19::chr18:31185530..31185578,+p@chr18:31185530..31185578
+
Hg19::chr18:33311016..33311032,-p@chr18:33311016..33311032
-
Hg19::chr18:35250432..35250444,+p@chr18:35250432..35250444
+
Hg19::chr18:73967160..73967162,-p@chr18:73967160..73967162
-
Hg19::chr18:73967189..73967200,-p@chr18:73967189..73967200
-
Hg19::chr18:73967203..73967220,-p@chr18:73967203..73967220
-
Hg19::chr18:74671119..74671124,+p@chr18:74671119..74671124
+
Hg19::chr18:8331753..8331793,+p@chr18:8331753..8331793
+
Hg19::chr19:46520090..46520102,-p@chr19:46520090..46520102
-
Hg19::chr19:46531064..46531073,+p@chr19:46531064..46531073
+
Hg19::chr19:46531131..46531136,+p@chr19:46531131..46531136
+
Hg19::chr19:46763326..46763349,+p@chr19:46763326..46763349
+
Hg19::chr19:46763651..46763662,+p@chr19:46763651..46763662
+
Hg19::chr19:46763803..46763808,-p@chr19:46763803..46763808
-
Hg19::chr19:51586029..51586039,-p2@KLK14
Hg19::chr19:56681707..56681748,-p@chr19:56681707..56681748
-
Hg19::chr19:9811101..9811112,-p3@ZNF812
Hg19::chr19:9811125..9811144,-p2@ZNF812
Hg19::chr1:11908185..11908202,-p6@NPPA
Hg19::chr1:11908227..11908236,-p8@NPPA
Hg19::chr1:15904346..15904358,-p@chr1:15904346..15904358
-
Hg19::chr1:194327155..194327162,-p@chr1:194327155..194327162
-
Hg19::chr1:223276523..223276530,-p@chr1:223276523..223276530
-
Hg19::chr1:223919301..223919303,+p@chr1:223919301..223919303
+
Hg19::chr1:225650299..225650317,-p@chr1:225650299..225650317
-
Hg19::chr1:226071797..226071822,-p@chr1:226071797..226071822
-
Hg19::chr1:28384655..28384680,-p7@EYA3
Hg19::chr1:6534668..6534704,-p@chr1:6534668..6534704
-
Hg19::chr1:67021937..67021942,+p@chr1:67021937..67021942
+
Hg19::chr1:79654075..79654086,-p@chr1:79654075..79654086
-
Hg19::chr21:29774393..29774422,-p@chr21:29774393..29774422
-
Hg19::chr21:29774431..29774441,-p@chr21:29774431..29774441
-
Hg19::chr21:39465959..39465961,+p@chr21:39465959..39465961
+
Hg19::chr21:43917055..43917058,-p@chr21:43917055..43917058
-
Hg19::chr22:38539185..38539224,-p9@PLA2G6
Hg19::chr22:38539262..38539297,-p11@PLA2G6
Hg19::chr2:120488121..120488144,-p@chr2:120488121..120488144
-
Hg19::chr2:148259693..148259714,-p@chr2:148259693..148259714
-
Hg19::chr2:170573896..170573900,-p@chr2:170573896..170573900
-
Hg19::chr2:176962389..176962394,-p@chr2:176962389..176962394
-
Hg19::chr2:21444025..21444055,+p1@ENST00000435237
Hg19::chr2:234862280..234862298,+p9@TRPM8
Hg19::chr2:234862313..234862320,+p15@TRPM8
Hg19::chr2:234862392..234862408,+p5@TRPM8
Hg19::chr2:234862409..234862414,+p14@TRPM8
Hg19::chr2:234862417..234862434,+p6@TRPM8
Hg19::chr2:234862436..234862439,+p16@TRPM8
Hg19::chr2:235841327..235841336,+p@chr2:235841327..235841336
+
Hg19::chr2:238385078..238385087,-p@chr2:238385078..238385087
-
Hg19::chr2:241625343..241625356,+p4@ENST00000407635
Hg19::chr2:241625364..241625374,+p5@ENST00000407635
Hg19::chr2:241625384..241625391,+p10@ENST00000407635
Hg19::chr2:241625475..241625482,+p8@ENST00000407635
Hg19::chr2:241625540..241625541,+p14@ENST00000407635
Hg19::chr2:241625548..241625569,+p1@ENST00000407635
Hg19::chr2:241625621..241625629,+p2@ENST00000407635
Hg19::chr2:241625689..241625696,+p7@ENST00000407635
Hg19::chr2:241625703..241625706,+p12@ENST00000407635
Hg19::chr2:28785672..28785682,+p@chr2:28785672..28785682
+
Hg19::chr2:28785693..28785704,+p@chr2:28785693..28785704
+
Hg19::chr2:28785707..28785729,+p@chr2:28785707..28785729
+
Hg19::chr2:3131535..3131547,-p@chr2:3131535..3131547
-
Hg19::chr3:102635374..102635381,-p@chr3:102635374..102635381
-
Hg19::chr3:102635409..102635414,-p@chr3:102635409..102635414
-
Hg19::chr3:102635473..102635480,-p@chr3:102635473..102635480
-
Hg19::chr3:142338164..142338210,+p@chr3:142338164..142338210
+
Hg19::chr3:145094664..145094665,+p@chr3:145094664..145094665
+
Hg19::chr4:10734349..10734351,-p@chr4:10734349..10734351
-
Hg19::chr4:185018490..185018512,-p@chr4:185018490..185018512
-
Hg19::chr4:185426203..185426209,-p@chr4:185426203..185426209
-
Hg19::chr4:23882555..23882575,-p4@HQ695733
Hg19::chr4:3310694..3310716,-p@chr4:3310694..3310716
-
Hg19::chr4:3344392..3344399,+p@chr4:3344392..3344399
+
Hg19::chr4:3344412..3344423,+p@chr4:3344412..3344423
+
Hg19::chr4:3344434..3344441,+p@chr4:3344434..3344441
+
Hg19::chr4:3344577..3344588,+p@chr4:3344577..3344588
+
Hg19::chr5:102141951..102141981,+p@chr5:102141951..102141981
+
Hg19::chr5:102143544..102143550,+p42@PAM
Hg19::chr5:102143894..102143910,+p6@PAM
Hg19::chr5:1445539..1445558,-p1@SLC6A3
Hg19::chr5:30198094..30198099,+p@chr5:30198094..30198099
+
Hg19::chr5:79097476..79097484,+p@chr5:79097476..79097484
+
Hg19::chr6:104852320..104852330,-p@chr6:104852320..104852330
-
Hg19::chr6:154707166..154707170,-p@chr6:154707166..154707170
-
Hg19::chr6:154710410..154710428,-p@chr6:154710410..154710428
-
Hg19::chr6:154715743..154715749,-p@chr6:154715743..154715749
-
Hg19::chr6:154831779..154831801,-p1@CNKSR3
Hg19::chr6:154831810..154831825,-p3@CNKSR3
Hg19::chr6:154858334..154858342,-p@chr6:154858334..154858342
-
Hg19::chr6:154858693..154858698,+p@chr6:154858693..154858698
+
Hg19::chr6:154858754..154858762,+p@chr6:154858754..154858762
+
Hg19::chr6:1608025..1608034,+p@chr6:1608025..1608034
+
Hg19::chr6:161637770..161637773,-p@chr6:161637770..161637773
-
Hg19::chr6:169224860..169224875,+p@chr6:169224860..169224875
+
Hg19::chr6:21200990..21201016,+p3@CDKAL1
Hg19::chr6:21201020..21201041,+p4@CDKAL1
Hg19::chr6:39526005..39526014,-p@chr6:39526005..39526014
-
Hg19::chr7:128514881..128514892,-p@chr7:128514881..128514892
-
Hg19::chr7:138721040..138721056,+p@chr7:138721040..138721056
+
Hg19::chr7:147741638..147741652,+p@chr7:147741638..147741652
+
Hg19::chr7:147741662..147741672,+p@chr7:147741662..147741672
+
Hg19::chr7:147741674..147741689,+p@chr7:147741674..147741689
+
Hg19::chr7:147741691..147741703,+p@chr7:147741691..147741703
+
Hg19::chr7:157944243..157944249,-p@chr7:157944243..157944249
-
Hg19::chr7:1965161..1965171,-p@chr7:1965161..1965171
-
Hg19::chr7:1968200..1968208,-p@chr7:1968200..1968208
-
Hg19::chr7:1968236..1968246,-p@chr7:1968236..1968246
-
Hg19::chr7:1968249..1968274,-p@chr7:1968249..1968274
-
Hg19::chr7:1968292..1968302,-p@chr7:1968292..1968302
-
Hg19::chr7:1968315..1968322,-p@chr7:1968315..1968322
-
Hg19::chr7:1968325..1968349,-p@chr7:1968325..1968349
-
Hg19::chr7:26415872..26415875,-p4@ENST00000451368
Hg19::chr7:26415877..26415903,-p1@ENST00000451368
Hg19::chr7:26416577..26416604,-p5@ENST00000451264
Hg19::chr7:26439057..26439073,-p@chr7:26439057..26439073
-
Hg19::chr7:26565580..26565622,+p@chr7:26565580..26565622
+
Hg19::chr7:26589319..26589327,+p@chr7:26589319..26589327
+
Hg19::chr7:26590563..26590574,-p@chr7:26590563..26590574
-
Hg19::chr7:26590581..26590596,-p@chr7:26590581..26590596
-
Hg19::chr7:26590606..26590616,-p@chr7:26590606..26590616
-
Hg19::chr7:26657673..26657685,-p@chr7:26657673..26657685
-
Hg19::chr7:26657707..26657715,-p@chr7:26657707..26657715
-
Hg19::chr7:44574294..44574303,-p@chr7:44574294..44574303
-
Hg19::chr7:44574304..44574314,-p@chr7:44574304..44574314
-
Hg19::chr7:44574327..44574332,-p@chr7:44574327..44574332
-
Hg19::chr8:143295119..143295149,-p@chr8:143295119..143295149
-
Hg19::chr8:145731609..145731641,+p@chr8:145731609..145731641
+
Hg19::chr8:20487277..20487282,+p@chr8:20487277..20487282
+
Hg19::chr8:81084875..81084896,-p@chr8:81084875..81084896
-
Hg19::chr8:82275651..82275662,+p@chr8:82275651..82275662
+
Hg19::chr9:118982149..118982158,+p@chr9:118982149..118982158
+
Hg19::chr9:138661786..138661830,+p@chr9:138661786..138661830
+
Hg19::chr9:138999405..138999415,-p@chr9:138999405..138999415
-
Hg19::chr9:95426545..95426559,-p@chr9:95426545..95426559
-
Hg19::chrX:154251771..154251775,-p@chrX:154251771..154251775
-
Hg19::chrX:39923656..39923670,-p@chrX:39923656..39923670
-
Hg19::chrX:52840308..52840338,+p@chrX:52840308..52840338
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005329dopamine transmembrane transporter activity0.0361027159925986
GO:0004598peptidylamidoglycolate lyase activity0.0361027159925986
GO:0005330dopamine:sodium symporter activity0.0361027159925986
GO:0060134prepulse inhibition0.0361027159925986
GO:0042637catagen0.0361027159925986
GO:0042424catecholamine catabolic process0.0361027159925986
GO:0021984adenohypophysis development0.0361027159925986
GO:0042420dopamine catabolic process0.0361027159925986
GO:0004504peptidylglycine monooxygenase activity0.0361027159925986
GO:0048585negative regulation of response to stimulus0.0361027159925986
GO:0042069regulation of catecholamine metabolic process0.0361027159925986
GO:0005087Ran guanyl-nucleotide exchange factor activity0.0361027159925986
GO:0001964startle response0.0361027159925986
GO:0015872dopamine transport0.0361027159925986
GO:0042416dopamine biosynthetic process0.0361027159925986
GO:0032102negative regulation of response to external stimulus0.0361027159925986
GO:0042053regulation of dopamine metabolic process0.0361027159925986
GO:0008504monoamine transmembrane transporter activity0.0426118536849584
GO:0050709negative regulation of protein secretion0.0460106438605772
GO:0015844monoamine transport0.0460106438605772
GO:0048820hair follicle maturation0.0487883969281202
GO:0032101regulation of response to external stimulus0.0487883969281202



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
adult organism8.56e-32115
regional part of nervous system1.28e-3094
nervous system1.28e-3094
central nervous system3.45e-3082
neural tube1.32e-2757
neural rod1.32e-2757
future spinal cord1.32e-2757
neural keel1.32e-2757
brain5.23e-2569
future brain5.23e-2569
regional part of brain2.89e-2359
ectoderm-derived structure1.07e-22169
ectoderm1.88e-22173
presumptive ectoderm1.88e-22173
neural plate5.45e-2286
presumptive neural plate5.45e-2286
neurectoderm2.37e-2190
anterior neural tube4.81e-2142
regional part of forebrain8.37e-2141
forebrain8.37e-2141
future forebrain8.37e-2141
head6.62e-19123
anterior region of body8.79e-19129
craniocervical region8.79e-19129
gray matter1.55e-1734
brain grey matter1.55e-1734
telencephalon2.86e-1734
regional part of telencephalon1.04e-1633
cerebral hemisphere1.33e-1632
pre-chordal neural plate1.24e-1561
anatomical conduit3.78e-15241
anatomical cluster1.31e-14286
organ part3.26e-14219
multi-tissue structure1.02e-13347
cerebral cortex5.44e-1325
pallium5.44e-1325
regional part of cerebral cortex9.50e-1322
organism subdivision1.76e-12365
tube3.09e-12194
neocortex5.48e-1220
epithelium4.10e-11309
cell layer1.05e-10312
organ2.19e-09511
trunk region element5.87e-08107
multi-cellular organism8.73e-08659
posterior neural tube1.02e-0715
chordal neural plate1.02e-0715
digestive system2.03e-07155
digestive tract2.03e-07155
primitive gut2.03e-07155
segmental subdivision of nervous system8.83e-0713
Disease
Ontology termp-valuen
cell type cancer1.49e-09143
carcinoma2.25e-07106


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


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