FF:11215-116A9: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00005496 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005496 | ||
|accession_numbers=CAGE;DRX008440;DRR009312;DRZ000737;DRZ002122;DRZ012087;DRZ013472 | |||
|accession_numbers_RNASeq=sRNA-Seq;DRX037259;DRR041625;DRZ007267 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0000966,UBERON:0000970,UBERON:0000019,UBERON:0000483,UBERON:0000033,UBERON:0000479,UBERON:0004121,UBERON:0000064,UBERON:0010314,UBERON:0000047,UBERON:0000062,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0000063,UBERON:0004923,UBERON:0001444,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000119,UBERON:0005388,UBERON:0000020,UBERON:0010371,UBERON:0007625,UBERON:0001781,UBERON:0001032,UBERON:0010317,UBERON:0001782,UBERON:0004088,UBERON:0000153,UBERON:0007811,UBERON:0002104,UBERON:0001802,UBERON:0004456,UBERON:0001456,UBERON:0010230 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0002371,CL:0000325,CL:0000147,CL:0000255,CL:0000149,CL:0002586 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000158 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score=chr14:57277178..57277203,-!p1@OTX2!2.18!152.07!OTX2;;chr11:61520075..61520136,+!p1@C11orf9!1.90!160.79!C11orf9;;chr14:57272369..57272391,-!p2@OTX2!1.85!70.52!OTX2;;chr9:126774018..126774055,+!p1@LHX2!1.84!67.45!LHX2;;chr18:56940611..56940660,-!p1@RAX!1.64!42.57!RAX;;chr2:45168875..45168916,+!p1@SIX3!1.57!36.16!SIX3;;chr2:45168834..45168847,+!p2@SIX3!1.53!33.08!SIX3;;chr6:1312325..1312340,+!p1@FOXQ1!1.52!51.03!FOXQ1;;chr11:61522844..61522875,+!p2@C11orf9!1.42!25.13!C11orf9;;chr16:1031762..1031781,+!p1@SOX8!1.38!23.08!SOX8;;chr12:66218255..66218304,+!p3@HMGA2!1.35!56.42!HMGA2;;chr9:126774058..126774081,+!p3@LHX2!1.33!20.26!LHX2;;chr2:45169193..45169219,+!p3@SIX3!1.32!20.00!SIX3;;chr22:38380543..38380569,-!p1@SOX10!1.29!18.46!SOX10;;chr15:42749722..42749739,-!p2@ZFP106!1.26!30.77!ZFP106;;chr3:52001448..52001478,-!p2@PCBP4!1.24!220.80!PCBP4;;chr9:126773880..126773895,+!p2@LHX2!1.23!15.90!LHX2;;chr1:2985760..2985774,+!p1@PRDM16!1.21!15.13!PRDM16;;chr6:34204921..34204939,+!p3@HMGA1!1.16!394.93!HMGA1;;chr7:100065686..100065701,-!p2@TSC22D4!1.15!13.08!TSC22D4;;chr2:5832508..5832524,+!p1@SOX11!1.15!13.08!SOX11;;chr6:34204672..34204692,+!p1@HMGA1!1.14!1424.32!HMGA1;;chr18:56940663..56940691,-!p2@RAX!1.12!12.05!RAX;;chr12:66218212..66218244,+!p5@HMGA2!1.10!16.93!HMGA2;;chr14:57277098..57277116,-!p3@OTX2!1.10!11.54!OTX2;;chr5:72744445..72744466,-!p2@FOXD1!1.09!18.98!FOXD1;;chr19:48773337..48773339,+!p2@ZNF114!1.08!11.03!ZNF114;;chr3:52001426..52001447,-!p3@PCBP4!1.05!29.49!PCBP4;;chr12:66218183..66218209,+!p4@HMGA2!1.04!19.23!HMGA2;;chr3:25469724..25469773,+!p1@RARB!1.02!13.85!RARB;;chr11:31832658..31832681,-!p1@PAX6!1.02!9.49!PAX6;;chr5:92918919..92918942,+!p1@NR2F1!1.01!42.31!NR2F1;;chr2:45169143..45169167,+!p5@SIX3!1.01!9.23!SIX3;;chr17:7492684..7492778,-!p2@SOX15!1.00!19.49!SOX15;;chr11:65667884..65667895,-!p2@FOSL1!0.99!34.62!FOSL1;;chr3:69915385..69915438,+!p3@MITF!0.99!8.72!MITF;;chr2:45169179..45169190,+!p8@SIX3!0.98!8.46!SIX3;;chr15:83953397..83953425,-!p1@BNC1!0.96!9.49!BNC1;;chr4:299227..299272,-!p1@ZNF732!0.96!8.21!ZNF732;;chr12:66218378..66218401,+!p6@HMGA2!0.95!12.57!HMGA2;;chr3:25470156..25470227,+!p2@RARB!0.95!7.95!RARB;;chr2:45168856..45168867,+!p7@SIX3!0.93!7.44!SIX3;;chr4:54966328..54966335,+!p1@GSX2!0.93!7.44!GSX2;;chr7:64838786..64838809,+!p2@ZNF92!0.88!39.24!ZNF92;;chr6:19837592..19837621,+!p1@ID4!0.87!41.29!ID4;;chr12:66218598..66218645,+!p2@HMGA2!0.87!31.54!HMGA2;;chr13:36871902..36872023,-!p1@CCDC169-SOHLH2,p1@CCDC169,p1@SOHLH2!0.87!14.62!SOHLH2;;chr3:69915369..69915381,+!p4@MITF!0.85!6.15!MITF;;chr22:41763452..41763466,+!p2@TEF!0.82!5.64!TEF;;chr17:70117153..70117174,+!p1@SOX9!0.81!61.29!SOX9;;chr3:25470062..25470084,+!p4@RARB!0.81!5.39!RARB;;chr2:71127699..71127744,+!p1@VAX2!0.80!11.54!VAX2;;chr11:65686802..65686818,+!p6@DRAP1!0.78!9.23!DRAP1;;chr15:66994615..66994630,+!p3@SMAD6!0.78!7.44!SMAD6;;chr15:66994663..66994680,+!p1@SMAD6!0.77!12.31!SMAD6;;chr3:52001396..52001425,-!p4@PCBP4!0.77!9.23!PCBP4;;chr2:63277948..63277974,+!p1@OTX1!0.77!4.87!OTX1;;chr13:72441315..72441454,-!p1@DACH1!0.76!10.00!DACH1;;chr12:54785074..54785122,-!p2@ZNF385A!0.76!7.69!ZNF385A;;chr11:65667846..65667868,-!p1@FOSL1!0.75!136.18!FOSL1;;chr5:92918894..92918912,+!p2@NR2F1!0.75!16.67!NR2F1;;chr5:72744594..72744609,-!p1@FOXD1!0.74!22.82!FOXD1;;chr1:170633348..170633399,+!p2@PRRX1!0.74!6.41!PRRX1;;chr12:66218152..66218174,+!p10@HMGA2!0.74!4.87!HMGA2;;chr1:41827095..41827155,+!p1@FOXO6!0.73!6.15!FOXO6;;chr3:141121847..141121868,+!p5@ZBTB38!0.71!6.67!ZBTB38;;chr12:66218573..66218596,+!p7@HMGA2!0.71!6.41!HMGA2;;chr5:92918860..92918871,+!p10@NR2F1!0.71!4.62!NR2F1;;chr5:92918768..92918783,+!p8@NR2F1!0.71!4.10!NR2F1;;chr11:65668011..65668020,-!p3@FOSL1!0.71!4.10!FOSL1;;chr9:128509663..128509715,+!p1@PBX3!0.70!15.13!PBX3;;chr12:66218443..66218461,+!p8@HMGA2!0.70!5.39!HMGA2;;chr13:37494275..37494304,-!p2@SMAD9!0.69!3.85!SMAD9;;chr7:101917407..101917443,+!p3@CUX1!0.69!3.85!CUX1;;chr2:45168959..45168990,+!p6@SIX3!0.69!3.85!SIX3;;chr19:57352087..57352102,-!p1@PEG3,p1@ZIM2!0.69!3.85!PEG3;;chr11:65686732..65686756,+!p2@DRAP1!0.68!17.95!DRAP1;;chr19:45260775..45260838,+!p5@BCL3!0.68!5.13!BCL3;;chr12:26277956..26277980,-!p1@BHLHE41!0.67!14.87!BHLHE41;;chr14:21994337..21994442,-!p1@SALL2!0.67!11.28!SALL2;;chr8:86089369..86089408,+!p1@E2F5!0.66!10.77!E2F5;;chr14:57277163..57277168,-!p4@OTX2!0.66!3.59!OTX2;;chr16:86612320..86612394,+!p1@FOXL1!0.66!3.59!FOXL1;;chr2:45168997..45169020,+!p4@SIX3!0.66!3.59!SIX3;;chr2:5832493..5832507,+!p2@SOX11!0.66!3.59!SOX11;;chr3:128206762..128206781,-!p2@GATA2!0.65!25.13!GATA2;;chr15:66994561..66994597,+!p2@SMAD6!0.65!9.23!SMAD6;;chr3:12329358..12329393,+!p3@PPARG!0.64!9.23!PPARG;;chr20:6748325..6748352,+!p1@BMP2!0.64!5.13!BMP2;;chr19:48325184..48325211,+!p1@CRX!0.64!3.33!CRX;;chr12:125003087..125003141,-!p4@NCOR2!0.63!4.36!NCOR2;;chr3:12330560..12330579,+!p1@PPARG!0.63!3.85!PPARG;;chr19:53496768..53496799,-!p1@ZNF702P!0.62!5.39!ZNF702P;;chr13:37494248..37494260,-!p3@SMAD9!0.61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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000066;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000147;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002586;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000966;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000970;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001781;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0007625 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
| Line 34: | Line 43: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Retinal%2520Pigment%2520Epithelial%2520Cells%252c%2520donor0.CNhs10842.11215-116A9.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Retinal%2520Pigment%2520Epithelial%2520Cells%252c%2520donor0.CNhs10842.11215-116A9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Retinal%2520Pigment%2520Epithelial%2520Cells%252c%2520donor0.CNhs10842.11215-116A9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Retinal%2520Pigment%2520Epithelial%2520Cells%252c%2520donor0.CNhs10842.11215-116A9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Retinal%2520Pigment%2520Epithelial%2520Cells%252c%2520donor0.CNhs10842.11215-116A9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11215-116A9 | |id=FF:11215-116A9 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000158 | ||
|is_obsolete= | |||
|library_id=CNhs10842 | |||
|library_id_phase_based=2:CNhs10842 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11215 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10015.CCGTCC.11215 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11215 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10015.CCGTCC.11215 | |||
|name=Retinal Pigment Epithelial Cells, donor0 | |name=Retinal Pigment Epithelial Cells, donor0 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 41: | Line 64: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs10842,LSID700,release009,COMPLETED | |profile_hcage=CNhs10842,LSID700,release009,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=SRhi10015,,, | |profile_srnaseq=SRhi10015,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.089905147355422,0,0,0,0,-0.061172776168247,0,-0.178216878275375,-0.282403560576942,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0944908321788258,0,0,0,0,0,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0,0,-0.0559945696105909,0,0,0,0,0,0,0,0,0.280976718137364,0,0,0,0.099145253918139,0,0.0114846210516754,0,-0.0969923612426051,0,0,0.00180162670504215,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0220445301092218,0,0,0,0,0,0,0.0292405933078452,0,0,0,-0.039327902279106,-0.0578990656519045,0,0,0,0.099145253918139,-0.0980353512377064,-0.138477200800895,0,0,0,0.099145253918139,0,0,0,0,0,0,0,0,0,0,0,0,0,0.082808073474162,0,0,0,-0.138075567776705,-0.371277147169383,0,0,0,0,0,0 | |||
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| |||
|rna_box=116 | |rna_box=116 | ||
|rna_catalog_number=6545 | |rna_catalog_number=6545 | ||
| Line 55: | Line 81: | ||
|rna_tube_id=116A9 | |rna_tube_id=116A9 | ||
|rna_weight_ug=10 | |rna_weight_ug=10 | ||
|rnaseq_library_id=SRhi10015.CCGTCC | |||
|sample_age= | |sample_age= | ||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |sample_cell_catalog=N/A | ||
|sample_cell_line= | |sample_cell_line= | ||
| Line 68: | Line 96: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.35483615513905e-259!GO:0005737;cytoplasm;3.06495126864867e-219!GO:0043226;organelle;1.48884234659953e-206!GO:0043229;intracellular organelle;2.90416397526933e-206!GO:0043231;intracellular membrane-bound organelle;1.44606576828842e-204!GO:0043227;membrane-bound organelle;3.54434658868503e-204!GO:0044422;organelle part;6.86677939933566e-169!GO:0044446;intracellular organelle part;1.70443361162553e-167!GO:0044444;cytoplasmic part;4.64112039317254e-163!GO:0032991;macromolecular complex;1.37007497162107e-110!GO:0030529;ribonucleoprotein complex;2.62436448721823e-95!GO:0044237;cellular metabolic process;7.50943589817247e-90!GO:0044238;primary metabolic process;8.68280937809311e-88!GO:0005739;mitochondrion;7.48612079880738e-87!GO:0043233;organelle lumen;4.93896031330904e-76!GO:0031974;membrane-enclosed lumen;4.93896031330904e-76!GO:0044428;nuclear part;5.54508078639171e-75!GO:0003723;RNA binding;2.57029344567763e-71!GO:0043170;macromolecule metabolic process;5.51111223142187e-70!GO:0005634;nucleus;2.68433002196926e-69!GO:0005515;protein binding;3.98908415950667e-67!GO:0031090;organelle membrane;5.28441053413256e-61!GO:0005840;ribosome;1.73679484762062e-59!GO:0044429;mitochondrial part;2.73460102342167e-58!GO:0043234;protein complex;1.09139134275549e-55!GO:0016043;cellular component organization and biogenesis;5.39491455479113e-53!GO:0009058;biosynthetic process;8.77924882093426e-53!GO:0006412;translation;3.47221281772942e-52!GO:0003735;structural constituent of ribosome;8.52089669493448e-51!GO:0031967;organelle envelope;1.69913067524986e-50!GO:0031975;envelope;3.69022022166212e-50!GO:0006396;RNA processing;5.50020835298514e-50!GO:0044249;cellular biosynthetic process;2.45134385457596e-48!GO:0033036;macromolecule localization;4.17698367542838e-46!GO:0019538;protein metabolic process;5.79180437114973e-46!GO:0015031;protein transport;1.3632013807962e-45!GO:0033279;ribosomal subunit;2.78819957108795e-44!GO:0005829;cytosol;4.2072242879133e-44!GO:0008104;protein localization;1.39613986769669e-42!GO:0045184;establishment of protein localization;2.04809017989809e-42!GO:0031981;nuclear lumen;2.62302829715601e-42!GO:0043228;non-membrane-bound organelle;5.50072764618583e-41!GO:0043232;intracellular non-membrane-bound organelle;5.50072764618583e-41!GO:0044260;cellular macromolecule metabolic process;5.52177100546838e-41!GO:0006996;organelle organization and biogenesis;1.05393503830229e-40!GO:0009059;macromolecule biosynthetic process;1.54133901958131e-40!GO:0044267;cellular protein metabolic process;2.70302918124534e-40!GO:0016071;mRNA metabolic process;9.11333364812529e-39!GO:0046907;intracellular transport;2.01383793380414e-38!GO:0008380;RNA splicing;1.05436357869738e-36!GO:0065003;macromolecular complex assembly;1.36581790256109e-36!GO:0005740;mitochondrial envelope;3.80683723129193e-36!GO:0043283;biopolymer metabolic process;1.05199094465125e-34!GO:0006397;mRNA processing;6.1322468141496e-34!GO:0031966;mitochondrial membrane;8.30130097049753e-34!GO:0019866;organelle inner membrane;2.09391332519962e-33!GO:0006259;DNA metabolic process;2.85288395407358e-33!GO:0022607;cellular component assembly;3.04968523575587e-33!GO:0005743;mitochondrial inner membrane;1.93980730189153e-31!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.31504827461535e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.45226014586769e-30!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.61143431720084e-30!GO:0010467;gene expression;7.66550614130119e-30!GO:0006886;intracellular protein transport;1.04278057089472e-29!GO:0007049;cell cycle;4.26630422031754e-29!GO:0048770;pigment granule;8.9453244227676e-29!GO:0042470;melanosome;8.9453244227676e-29!GO:0005681;spliceosome;1.72328662623769e-26!GO:0031980;mitochondrial lumen;4.84938106689354e-26!GO:0005759;mitochondrial matrix;4.84938106689354e-26!GO:0051649;establishment of cellular localization;1.54744792322962e-25!GO:0006119;oxidative phosphorylation;1.56913695320002e-25!GO:0012505;endomembrane system;2.07251228038875e-25!GO:0000166;nucleotide binding;2.31714139583754e-25!GO:0044445;cytosolic part;2.79646525877322e-25!GO:0051641;cellular localization;3.29313100539266e-25!GO:0005654;nucleoplasm;2.19566180563946e-24!GO:0044455;mitochondrial membrane part;3.66918806450023e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;5.29368936694363e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;5.41296647837344e-23!GO:0016462;pyrophosphatase activity;6.12500111651973e-23!GO:0015934;large ribosomal subunit;8.49361868284092e-23!GO:0000278;mitotic cell cycle;1.33084420827679e-22!GO:0015935;small ribosomal subunit;1.40559433781501e-22!GO:0022402;cell cycle process;8.56773952647158e-22!GO:0017111;nucleoside-triphosphatase activity;2.96948866358051e-21!GO:0006457;protein folding;5.48981747084204e-21!GO:0051186;cofactor metabolic process;8.69624735803884e-21!GO:0005783;endoplasmic reticulum;2.52808161713178e-20!GO:0044451;nucleoplasm part;2.21447575851986e-19!GO:0005746;mitochondrial respiratory chain;2.55197193936735e-19!GO:0005694;chromosome;6.06401663989702e-19!GO:0000087;M phase of mitotic cell cycle;1.52797022293126e-18!GO:0005730;nucleolus;1.52797022293126e-18!GO:0006974;response to DNA damage stimulus;2.52621930702927e-18!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.65883213504251e-18!GO:0007067;mitosis;3.12875060160152e-18!GO:0022618;protein-RNA complex assembly;4.38639695723347e-18!GO:0005761;mitochondrial ribosome;4.79307950215091e-18!GO:0000313;organellar ribosome;4.79307950215091e-18!GO:0044427;chromosomal part;1.28605534360094e-17!GO:0022403;cell cycle phase;1.55875472178178e-17!GO:0044265;cellular macromolecule catabolic process;2.05318308796699e-17!GO:0032553;ribonucleotide binding;2.10757354921323e-17!GO:0032555;purine ribonucleotide binding;2.10757354921323e-17!GO:0017076;purine nucleotide binding;2.39963549026949e-17!GO:0016874;ligase activity;2.73811337861605e-17!GO:0050136;NADH dehydrogenase (quinone) activity;6.39013122544907e-17!GO:0003954;NADH dehydrogenase activity;6.39013122544907e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;6.39013122544907e-17!GO:0044432;endoplasmic reticulum part;6.39013122544907e-17!GO:0044248;cellular catabolic process;8.54844664442523e-17!GO:0051301;cell division;1.61150014524084e-16!GO:0006732;coenzyme metabolic process;1.87870019614161e-16!GO:0009057;macromolecule catabolic process;5.78990992855932e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);7.94695888889717e-16!GO:0003676;nucleic acid binding;1.00330164576891e-15!GO:0000502;proteasome complex (sensu Eukaryota);1.13152662197103e-15!GO:0005635;nuclear envelope;1.41995527777857e-15!GO:0008135;translation factor activity, nucleic acid binding;1.72636309437053e-15!GO:0043285;biopolymer catabolic process;1.82932093519222e-15!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.91053434315149e-15!GO:0006281;DNA repair;2.13959904575538e-15!GO:0051276;chromosome organization and biogenesis;2.14371626281727e-15!GO:0042775;organelle ATP synthesis coupled electron transport;2.61876614561482e-15!GO:0042773;ATP synthesis coupled electron transport;2.61876614561482e-15!GO:0005794;Golgi apparatus;2.66392396916798e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);3.35252183918017e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;4.48502106316475e-15!GO:0030964;NADH dehydrogenase complex (quinone);4.95214124842739e-15!GO:0045271;respiratory chain complex I;4.95214124842739e-15!GO:0005747;mitochondrial respiratory chain complex I;4.95214124842739e-15!GO:0006511;ubiquitin-dependent protein catabolic process;6.11290566239556e-15!GO:0019941;modification-dependent protein catabolic process;7.10236866735469e-15!GO:0043632;modification-dependent macromolecule catabolic process;7.10236866735469e-15!GO:0006605;protein targeting;7.25453747397871e-15!GO:0000279;M phase;1.00086985017863e-14!GO:0006512;ubiquitin cycle;1.2171669666731e-14!GO:0044257;cellular protein catabolic process;1.38414495816824e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.48330974501356e-14!GO:0051082;unfolded protein binding;5.89456396877913e-14!GO:0042254;ribosome biogenesis and assembly;6.33954650607161e-14!GO:0031965;nuclear membrane;6.67942370863944e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;8.95653174054289e-14!GO:0000375;RNA splicing, via transesterification reactions;8.95653174054289e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;8.95653174054289e-14!GO:0006260;DNA replication;1.05228480429778e-13!GO:0005524;ATP binding;1.35584728439275e-13!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.40607818587539e-13!GO:0016192;vesicle-mediated transport;1.97870492697596e-13!GO:0032559;adenyl ribonucleotide binding;2.54176899299245e-13!GO:0044453;nuclear membrane part;3.24179330879423e-13!GO:0030163;protein catabolic process;3.41124958210955e-13!GO:0005789;endoplasmic reticulum membrane;3.52368323219818e-13!GO:0030554;adenyl nucleotide binding;3.79679882005281e-13!GO:0009719;response to endogenous stimulus;4.82261869844065e-13!GO:0048193;Golgi vesicle transport;6.13210338259488e-13!GO:0009055;electron carrier activity;6.5988589906374e-13!GO:0006163;purine nucleotide metabolic process;7.59906365679338e-13!GO:0009259;ribonucleotide metabolic process;8.44384593922933e-13!GO:0006325;establishment and/or maintenance of chromatin architecture;1.45096379768082e-12!GO:0008134;transcription factor binding;2.79323071171028e-12!GO:0006323;DNA packaging;5.36034514064384e-12!GO:0006164;purine nucleotide biosynthetic process;7.52593201464819e-12!GO:0009150;purine ribonucleotide metabolic process;8.11893495933087e-12!GO:0045333;cellular respiration;1.35300349429486e-11!GO:0003743;translation initiation factor activity;1.92472574971556e-11!GO:0006413;translational initiation;1.95323144762383e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.43264485695737e-11!GO:0009060;aerobic respiration;2.95400903681173e-11!GO:0009260;ribonucleotide biosynthetic process;3.06316785028236e-11!GO:0006399;tRNA metabolic process;3.16168008034207e-11!GO:0006461;protein complex assembly;3.16168008034207e-11!GO:0009056;catabolic process;3.37446566184366e-11!GO:0015630;microtubule cytoskeleton;3.38765181937424e-11!GO:0065004;protein-DNA complex assembly;5.80940857756104e-11!GO:0043412;biopolymer modification;6.33585903002332e-11!GO:0005643;nuclear pore;6.51597123747194e-11!GO:0042623;ATPase activity, coupled;7.47442696790282e-11!GO:0009152;purine ribonucleotide biosynthetic process;8.06844247159528e-11!GO:0008565;protein transporter activity;1.0870344037094e-10!GO:0009141;nucleoside triphosphate metabolic process;1.6768393847138e-10!GO:0016887;ATPase activity;1.69810442837645e-10!GO:0009199;ribonucleoside triphosphate metabolic process;1.79668645994237e-10!GO:0051188;cofactor biosynthetic process;1.93022265984404e-10!GO:0006446;regulation of translational initiation;2.05521873057024e-10!GO:0000074;regulation of progression through cell cycle;2.05911438250478e-10!GO:0051726;regulation of cell cycle;2.17382863854056e-10!GO:0006333;chromatin assembly or disassembly;3.1307876023137e-10!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.28222880316929e-10!GO:0009144;purine nucleoside triphosphate metabolic process;3.28222880316929e-10!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;3.67697889344997e-10!GO:0000785;chromatin;3.96568310637108e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.60008924187268e-10!GO:0065002;intracellular protein transport across a membrane;7.33315439150163e-10!GO:0016491;oxidoreductase activity;1.07923676970348e-09!GO:0006464;protein modification process;1.33216423600713e-09!GO:0016070;RNA metabolic process;1.60405078671023e-09!GO:0015986;ATP synthesis coupled proton transport;1.91325904840223e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.91325904840223e-09!GO:0003924;GTPase activity;2.61552141958176e-09!GO:0006364;rRNA processing;2.69626272070848e-09!GO:0009142;nucleoside triphosphate biosynthetic process;3.10305573855625e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.10305573855625e-09!GO:0016604;nuclear body;3.16514751192616e-09!GO:0006099;tricarboxylic acid cycle;3.17226790557516e-09!GO:0046356;acetyl-CoA catabolic process;3.17226790557516e-09!GO:0046034;ATP metabolic process;3.17226790557516e-09!GO:0006334;nucleosome assembly;4.84648447692614e-09!GO:0016023;cytoplasmic membrane-bound vesicle;4.90028190463571e-09!GO:0031988;membrane-bound vesicle;5.20575372925982e-09!GO:0005768;endosome;5.25895505515147e-09!GO:0050657;nucleic acid transport;5.34010911965527e-09!GO:0051236;establishment of RNA localization;5.34010911965527e-09!GO:0050658;RNA transport;5.34010911965527e-09!GO:0007005;mitochondrion organization and biogenesis;5.51755505690779e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;5.52883354235878e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;5.52883354235878e-09!GO:0030532;small nuclear ribonucleoprotein complex;5.75902120179728e-09!GO:0016072;rRNA metabolic process;5.98284149545403e-09!GO:0006403;RNA localization;6.14738607472694e-09!GO:0006084;acetyl-CoA metabolic process;6.32522270542385e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;7.11190456768718e-09!GO:0004812;aminoacyl-tRNA ligase activity;7.11190456768718e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;7.11190456768718e-09!GO:0009117;nucleotide metabolic process;7.50732010698584e-09!GO:0046930;pore complex;7.62068810372284e-09!GO:0019829;cation-transporting ATPase activity;8.88334005462656e-09!GO:0031497;chromatin assembly;1.14048474855468e-08!GO:0006913;nucleocytoplasmic transport;1.18027515996585e-08!GO:0043038;amino acid activation;1.18288337938015e-08!GO:0006418;tRNA aminoacylation for protein translation;1.18288337938015e-08!GO:0043039;tRNA aminoacylation;1.18288337938015e-08!GO:0005793;ER-Golgi intermediate compartment;1.39150762999941e-08!GO:0048475;coated membrane;1.71716463893745e-08!GO:0030117;membrane coat;1.71716463893745e-08!GO:0009108;coenzyme biosynthetic process;2.12007522856819e-08!GO:0051169;nuclear transport;3.12699702056565e-08!GO:0016740;transferase activity;4.63160558046877e-08!GO:0031982;vesicle;4.72359417292646e-08!GO:0051187;cofactor catabolic process;4.73037209172172e-08!GO:0006754;ATP biosynthetic process;4.79586069507711e-08!GO:0006753;nucleoside phosphate metabolic process;4.79586069507711e-08!GO:0016853;isomerase activity;4.81825655251907e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;4.84170769773028e-08!GO:0031410;cytoplasmic vesicle;5.31348660927136e-08!GO:0016469;proton-transporting two-sector ATPase complex;5.46255350393513e-08!GO:0005773;vacuole;6.37040890181976e-08!GO:0043687;post-translational protein modification;6.96543500175386e-08!GO:0003697;single-stranded DNA binding;7.28854190844784e-08!GO:0009109;coenzyme catabolic process;7.72838389532887e-08!GO:0008639;small protein conjugating enzyme activity;8.62206904326792e-08!GO:0004386;helicase activity;8.99569721404944e-08!GO:0043566;structure-specific DNA binding;9.32775628202602e-08!GO:0003712;transcription cofactor activity;9.87582223098756e-08!GO:0012501;programmed cell death;1.00560858067704e-07!GO:0006915;apoptosis;1.3295243025809e-07!GO:0006888;ER to Golgi vesicle-mediated transport;1.333825523532e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.40081219756298e-07!GO:0017038;protein import;1.6338176519112e-07!GO:0004842;ubiquitin-protein ligase activity;1.6858692994094e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.73784261987758e-07!GO:0015980;energy derivation by oxidation of organic compounds;1.75781163951875e-07!GO:0030120;vesicle coat;1.79393632964336e-07!GO:0030662;coated vesicle membrane;1.79393632964336e-07!GO:0044431;Golgi apparatus part;1.85026674271925e-07!GO:0005819;spindle;2.52975435975525e-07!GO:0019787;small conjugating protein ligase activity;2.76094929738376e-07!GO:0051028;mRNA transport;3.05625169082241e-07!GO:0000323;lytic vacuole;4.16682844678774e-07!GO:0005764;lysosome;4.16682844678774e-07!GO:0016126;sterol biosynthetic process;4.16682844678774e-07!GO:0016607;nuclear speck;4.91089478023055e-07!GO:0008026;ATP-dependent helicase activity;5.80985862255684e-07!GO:0006091;generation of precursor metabolites and energy;5.87373913028052e-07!GO:0006752;group transfer coenzyme metabolic process;6.35820581977425e-07!GO:0016787;hydrolase activity;6.82947591174867e-07!GO:0043623;cellular protein complex assembly;6.93060424198192e-07!GO:0045259;proton-transporting ATP synthase complex;6.98578803409341e-07!GO:0008219;cell death;8.26068405538215e-07!GO:0016265;death;8.26068405538215e-07!GO:0000775;chromosome, pericentric region;8.26068405538215e-07!GO:0005525;GTP binding;8.91067353496287e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.1032383159956e-06!GO:0007051;spindle organization and biogenesis;1.13446667892143e-06!GO:0008654;phospholipid biosynthetic process;1.5550763265954e-06!GO:0016568;chromatin modification;1.59508824592979e-06!GO:0005762;mitochondrial large ribosomal subunit;1.72901826707905e-06!GO:0000315;organellar large ribosomal subunit;1.72901826707905e-06!GO:0000245;spliceosome assembly;1.76487504858997e-06!GO:0005798;Golgi-associated vesicle;1.9746417083178e-06!GO:0005770;late endosome;2.17790106596582e-06!GO:0016881;acid-amino acid ligase activity;2.30035440305507e-06!GO:0051246;regulation of protein metabolic process;2.36522820003544e-06!GO:0005667;transcription factor complex;2.8220851134573e-06!GO:0005839;proteasome core complex (sensu Eukaryota);3.40813453166142e-06!GO:0006695;cholesterol biosynthetic process;3.54999656078392e-06!GO:0016779;nucleotidyltransferase activity;3.85220990102521e-06!GO:0000314;organellar small ribosomal subunit;4.70805388319732e-06!GO:0005763;mitochondrial small ribosomal subunit;4.70805388319732e-06!GO:0007010;cytoskeleton organization and biogenesis;6.23358375467073e-06!GO:0006613;cotranslational protein targeting to membrane;6.59851075975075e-06!GO:0032446;protein modification by small protein conjugation;6.6845019713421e-06!GO:0006261;DNA-dependent DNA replication;6.81934886914491e-06!GO:0032561;guanyl ribonucleotide binding;7.64980906949808e-06!GO:0019001;guanyl nucleotide binding;7.64980906949808e-06!GO:0048471;perinuclear region of cytoplasm;8.05906210475257e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.02288467181702e-05!GO:0045454;cell redox homeostasis;1.04948876905797e-05!GO:0016567;protein ubiquitination;1.07326504010892e-05!GO:0044440;endosomal part;1.2862023712514e-05!GO:0010008;endosome membrane;1.2862023712514e-05!GO:0031252;leading edge;1.31113555298751e-05!GO:0051325;interphase;1.33083967189404e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.46601075688251e-05!GO:0051329;interphase of mitotic cell cycle;1.53058567998632e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.64076519934901e-05!GO:0008610;lipid biosynthetic process;1.64725503083531e-05!GO:0005657;replication fork;1.76018096683242e-05!GO:0019752;carboxylic acid metabolic process;2.05471115530479e-05!GO:0006082;organic acid metabolic process;2.16628619023274e-05!GO:0043021;ribonucleoprotein binding;2.37776867687828e-05!GO:0005874;microtubule;2.45276927268659e-05!GO:0048523;negative regulation of cellular process;2.45276927268659e-05!GO:0004298;threonine endopeptidase activity;2.48635706716057e-05!GO:0006916;anti-apoptosis;2.59013717183547e-05!GO:0000139;Golgi membrane;2.64854977627042e-05!GO:0003899;DNA-directed RNA polymerase activity;2.66048797120161e-05!GO:0019748;secondary metabolic process;2.92833597745318e-05!GO:0006366;transcription from RNA polymerase II promoter;3.00275932838787e-05!GO:0043069;negative regulation of programmed cell death;3.37762978893084e-05!GO:0009165;nucleotide biosynthetic process;4.1032642335311e-05!GO:0043066;negative regulation of apoptosis;4.15675935718117e-05!GO:0044262;cellular carbohydrate metabolic process;4.23679781642062e-05!GO:0006793;phosphorus metabolic process;4.6603646671845e-05!GO:0006796;phosphate metabolic process;4.6603646671845e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;4.68966987108083e-05!GO:0016859;cis-trans isomerase activity;4.89024281012815e-05!GO:0005813;centrosome;4.90465207024641e-05!GO:0005815;microtubule organizing center;5.2288784524476e-05!GO:0031968;organelle outer membrane;5.323196807206e-05!GO:0045786;negative regulation of progression through cell cycle;5.66619314541064e-05!GO:0008094;DNA-dependent ATPase activity;5.66619314541064e-05!GO:0003724;RNA helicase activity;5.83743467942134e-05!GO:0005788;endoplasmic reticulum lumen;6.420488441772e-05!GO:0000151;ubiquitin ligase complex;7.33787097503802e-05!GO:0019867;outer membrane;7.70460181572109e-05!GO:0005905;coated pit;8.40746637963238e-05!GO:0006612;protein targeting to membrane;8.43507445259569e-05!GO:0005791;rough endoplasmic reticulum;9.62398777494398e-05!GO:0006839;mitochondrial transport;9.72069543067433e-05!GO:0006626;protein targeting to mitochondrion;9.7776104912688e-05!GO:0006414;translational elongation;0.000106766671561315!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000128950509523973!GO:0051427;hormone receptor binding;0.000144648583786227!GO:0000786;nucleosome;0.000158717419003037!GO:0043681;protein import into mitochondrion;0.000164209283682187!GO:0051170;nuclear import;0.000167887202925264!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000170819239373092!GO:0030659;cytoplasmic vesicle membrane;0.000210303956909215!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000215511806257927!GO:0005741;mitochondrial outer membrane;0.000239606523814811!GO:0006520;amino acid metabolic process;0.000274928657588903!GO:0000776;kinetochore;0.000276674597016248!GO:0006606;protein import into nucleus;0.000278766604917557!GO:0016363;nuclear matrix;0.000286195988618956!GO:0035257;nuclear hormone receptor binding;0.00029406896664958!GO:0046474;glycerophospholipid biosynthetic process;0.000302011190429425!GO:0000075;cell cycle checkpoint;0.000303970005177256!GO:0007059;chromosome segregation;0.000324358887196498!GO:0030867;rough endoplasmic reticulum membrane;0.000331838203380075!GO:0042981;regulation of apoptosis;0.00033497835733623!GO:0003714;transcription corepressor activity;0.00034297363187373!GO:0007017;microtubule-based process;0.000350644419297682!GO:0042440;pigment metabolic process;0.000366430345140704!GO:0005769;early endosome;0.000371836937474059!GO:0042802;identical protein binding;0.000376344749932601!GO:0016310;phosphorylation;0.000384442047491686!GO:0043067;regulation of programmed cell death;0.000396265807650533!GO:0006383;transcription from RNA polymerase III promoter;0.000415733460164112!GO:0008250;oligosaccharyl transferase complex;0.000424422275512438!GO:0050662;coenzyme binding;0.000429504004420177!GO:0044433;cytoplasmic vesicle part;0.000430416079847607!GO:0015631;tubulin binding;0.000435440146936067!GO:0030118;clathrin coat;0.000439429671996073!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000440465791387718!GO:0004576;oligosaccharyl transferase activity;0.000446248117451353!GO:0048519;negative regulation of biological process;0.000454648041023602!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000456560740319223!GO:0006720;isoprenoid metabolic process;0.000458831445988926!GO:0033116;ER-Golgi intermediate compartment membrane;0.000462029225259129!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000462029225259129!GO:0008033;tRNA processing;0.000471919116994908!GO:0003713;transcription coactivator activity;0.000514880436887067!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000523791161040574!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000544429298795772!GO:0051920;peroxiredoxin activity;0.000556518464618057!GO:0007006;mitochondrial membrane organization and biogenesis;0.000574754523625033!GO:0046467;membrane lipid biosynthetic process;0.000589675403108939!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000624811058444032!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000626461089737565!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000626461089737565!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000626461089737565!GO:0030880;RNA polymerase complex;0.000640666148078248!GO:0007088;regulation of mitosis;0.00064852611213632!GO:0000059;protein import into nucleus, docking;0.000650098379651728!GO:0005885;Arp2/3 protein complex;0.000661368429966751!GO:0051168;nuclear export;0.000665009928147522!GO:0012506;vesicle membrane;0.000668632449256659!GO:0003690;double-stranded DNA binding;0.000685101993076318!GO:0044255;cellular lipid metabolic process;0.000694664124928757!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000750818433778817!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000768378861526489!GO:0003684;damaged DNA binding;0.000800068624844335!GO:0019899;enzyme binding;0.000819493287970665!GO:0016860;intramolecular oxidoreductase activity;0.000843748164670396!GO:0007052;mitotic spindle organization and biogenesis;0.000843748164670396!GO:0008092;cytoskeletal protein binding;0.000870973583237047!GO:0046148;pigment biosynthetic process;0.000876829716653685!GO:0003729;mRNA binding;0.000944985260841137!GO:0030133;transport vesicle;0.00103935438220022!GO:0008186;RNA-dependent ATPase activity;0.00104351743596418!GO:0044452;nucleolar part;0.00109287895593067!GO:0051287;NAD binding;0.00110103246783716!GO:0018196;peptidyl-asparagine modification;0.00115866593178717!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00115866593178717!GO:0016044;membrane organization and biogenesis;0.0011646561265847!GO:0030036;actin cytoskeleton organization and biogenesis;0.00117141052929081!GO:0031124;mRNA 3'-end processing;0.00118337140406321!GO:0006643;membrane lipid metabolic process;0.00119214663219503!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00124309475134412!GO:0006007;glucose catabolic process;0.00127351965232441!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.00137161730148406!GO:0019843;rRNA binding;0.00143268469410815!GO:0016125;sterol metabolic process;0.00151747768918849!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00152228090071863!GO:0000428;DNA-directed RNA polymerase complex;0.00152228090071863!GO:0048487;beta-tubulin binding;0.00154530870013548!GO:0016564;transcription repressor activity;0.0015629695767451!GO:0030663;COPI coated vesicle membrane;0.00156499395128217!GO:0030126;COPI vesicle coat;0.00156499395128217!GO:0005684;U2-dependent spliceosome;0.00158537069356409!GO:0030658;transport vesicle membrane;0.00164341590218223!GO:0048500;signal recognition particle;0.00164551054970658!GO:0043284;biopolymer biosynthetic process;0.00165563602848471!GO:0003682;chromatin binding;0.00166606222618288!GO:0051087;chaperone binding;0.00169002723602263!GO:0007040;lysosome organization and biogenesis;0.00169535522616879!GO:0015992;proton transport;0.00172612497340537!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00184603824954514!GO:0015399;primary active transmembrane transporter activity;0.00184603824954514!GO:0006302;double-strand break repair;0.00186834618643278!GO:0006818;hydrogen transport;0.00188238150043739!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00193827521700118!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00193827521700118!GO:0031072;heat shock protein binding;0.00211888034114615!GO:0051252;regulation of RNA metabolic process;0.00216626728964443!GO:0005048;signal sequence binding;0.00218252888255587!GO:0003746;translation elongation factor activity;0.00218574216194394!GO:0001726;ruffle;0.0022085108256799!GO:0006378;mRNA polyadenylation;0.00224744264191554!GO:0022890;inorganic cation transmembrane transporter activity;0.00228564480163939!GO:0000096;sulfur amino acid metabolic process;0.00228870544879459!GO:0006519;amino acid and derivative metabolic process;0.00229232989629065!GO:0032508;DNA duplex unwinding;0.00229719635767734!GO:0032392;DNA geometric change;0.00229719635767734!GO:0006066;alcohol metabolic process;0.00229719635767734!GO:0007093;mitotic cell cycle checkpoint;0.0023448591946368!GO:0031324;negative regulation of cellular metabolic process;0.00240758719590659!GO:0006650;glycerophospholipid metabolic process;0.00240758719590659!GO:0006807;nitrogen compound metabolic process;0.00241067632908624!GO:0030660;Golgi-associated vesicle membrane;0.00245036799404108!GO:0016741;transferase activity, transferring one-carbon groups;0.00267467378004992!GO:0004004;ATP-dependent RNA helicase activity;0.00273548793822273!GO:0030176;integral to endoplasmic reticulum membrane;0.00273958378669751!GO:0051052;regulation of DNA metabolic process;0.00274614709288154!GO:0008168;methyltransferase activity;0.00282415436642499!GO:0051789;response to protein stimulus;0.00290739842442609!GO:0006986;response to unfolded protein;0.00290739842442609!GO:0065009;regulation of a molecular function;0.0029325919320572!GO:0008312;7S RNA binding;0.00294719339293364!GO:0043488;regulation of mRNA stability;0.00305816413581729!GO:0043487;regulation of RNA stability;0.00305816413581729!GO:0048037;cofactor binding;0.00307660812281603!GO:0008361;regulation of cell size;0.00311370598478266!GO:0005774;vacuolar membrane;0.0031263903880292!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00312695770458472!GO:0046489;phosphoinositide biosynthetic process;0.00313613692309038!GO:0008180;signalosome;0.00325515341479842!GO:0030119;AP-type membrane coat adaptor complex;0.00340143314168416!GO:0051539;4 iron, 4 sulfur cluster binding;0.00345925449597112!GO:0007264;small GTPase mediated signal transduction;0.00351275200583521!GO:0001558;regulation of cell growth;0.00357626543043719!GO:0009308;amine metabolic process;0.00357626543043719!GO:0007033;vacuole organization and biogenesis;0.00359460096706789!GO:0006402;mRNA catabolic process;0.0036896808081868!GO:0050794;regulation of cellular process;0.00372163972324831!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00377139227049597!GO:0045047;protein targeting to ER;0.00377139227049597!GO:0006220;pyrimidine nucleotide metabolic process;0.00390468821197653!GO:0031902;late endosome membrane;0.00404813138928345!GO:0006595;polyamine metabolic process;0.00404813138928345!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00404813138928345!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00411274758556882!GO:0006268;DNA unwinding during replication;0.00413268091416294!GO:0016049;cell growth;0.00415664233859232!GO:0006644;phospholipid metabolic process;0.0042777126874557!GO:0030029;actin filament-based process;0.00442042838046628!GO:0007034;vacuolar transport;0.00455726560781521!GO:0016563;transcription activator activity;0.00457291026307817!GO:0030137;COPI-coated vesicle;0.00462976463397255!GO:0030131;clathrin adaptor complex;0.00469172020895474!GO:0004527;exonuclease activity;0.00474812689279657!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00482782888608992!GO:0008022;protein C-terminus binding;0.00483675930501784!GO:0008632;apoptotic program;0.00484490012218228!GO:0003678;DNA helicase activity;0.0048936307500848!GO:0016197;endosome transport;0.00490170858216178!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00501274866317393!GO:0009892;negative regulation of metabolic process;0.00511177803845856!GO:0030521;androgen receptor signaling pathway;0.00517193384184415!GO:0006401;RNA catabolic process;0.00520101068475461!GO:0006891;intra-Golgi vesicle-mediated transport;0.00544186408389274!GO:0006352;transcription initiation;0.00544449885861028!GO:0035258;steroid hormone receptor binding;0.00546358277692956!GO:0006144;purine base metabolic process;0.00597341255178965!GO:0005637;nuclear inner membrane;0.00607212641781339!GO:0046483;heterocycle metabolic process;0.00613834171321672!GO:0006629;lipid metabolic process;0.00633676742424076!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00633676742424076!GO:0015002;heme-copper terminal oxidase activity;0.00633676742424076!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00633676742424076!GO:0004129;cytochrome-c oxidase activity;0.00633676742424076!GO:0005869;dynactin complex;0.00633774309013082!GO:0005758;mitochondrial intermembrane space;0.00633774309013082!GO:0006733;oxidoreduction coenzyme metabolic process;0.00637566019554125!GO:0016272;prefoldin complex;0.00649710710383771!GO:0006778;porphyrin metabolic process;0.00656818439643789!GO:0033013;tetrapyrrole metabolic process;0.00656818439643789!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00661549420453056!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00669987963376896!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00670860060912214!GO:0030134;ER to Golgi transport vesicle;0.00680363572901525!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.00695801144898994!GO:0043022;ribosome binding;0.00698506284754898!GO:0051540;metal cluster binding;0.00709461648358776!GO:0051536;iron-sulfur cluster binding;0.00709461648358776!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00736713464670793!GO:0031123;RNA 3'-end processing;0.00765076385119215!GO:0042393;histone binding;0.00775321318601275!GO:0016251;general RNA polymerase II transcription factor activity;0.00776885573500418!GO:0030027;lamellipodium;0.00827334988452903!GO:0005832;chaperonin-containing T-complex;0.00865642959042207!GO:0044437;vacuolar part;0.00875664029299231!GO:0006310;DNA recombination;0.00877888512135772!GO:0030132;clathrin coat of coated pit;0.00886053752960489!GO:0030127;COPII vesicle coat;0.00897765814610135!GO:0012507;ER to Golgi transport vesicle membrane;0.00897765814610135!GO:0016408;C-acyltransferase activity;0.00908167474276719!GO:0031970;organelle envelope lumen;0.00908167474276719!GO:0006289;nucleotide-excision repair;0.00911478920458042!GO:0005765;lysosomal membrane;0.00922448664155532!GO:0007021;tubulin folding;0.00935530843309879!GO:0005853;eukaryotic translation elongation factor 1 complex;0.00954573457786245!GO:0006740;NADPH regeneration;0.00964271904864017!GO:0006098;pentose-phosphate shunt;0.00964271904864017!GO:0046519;sphingoid metabolic process;0.00974446673887448!GO:0000049;tRNA binding;0.00988886122957578!GO:0017166;vinculin binding;0.0100072091484761!GO:0043624;cellular protein complex disassembly;0.0103056883149477!GO:0006611;protein export from nucleus;0.0104399740148087!GO:0008287;protein serine/threonine phosphatase complex;0.0104469586711401!GO:0043492;ATPase activity, coupled to movement of substances;0.0105929931353407!GO:0032984;macromolecular complex disassembly;0.0106559408729773!GO:0006096;glycolysis;0.0107017555774291!GO:0006672;ceramide metabolic process;0.0107872839679189!GO:0030496;midbody;0.0110480566798987!GO:0005876;spindle microtubule;0.0111624848258545!GO:0008299;isoprenoid biosynthetic process;0.0112480985112546!GO:0022411;cellular component disassembly;0.0112846922778614!GO:0006979;response to oxidative stress;0.0113375368045126!GO:0009116;nucleoside metabolic process;0.0115068282599766!GO:0005996;monosaccharide metabolic process;0.0118137970689831!GO:0003711;transcription elongation regulator activity;0.0119372497173563!GO:0006118;electron transport;0.0125079598053121!GO:0000339;RNA cap binding;0.0126880332308913!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0128556575440269!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0129272329936453!GO:0004448;isocitrate dehydrogenase activity;0.0129841013672093!GO:0006509;membrane protein ectodomain proteolysis;0.0129841013672093!GO:0033619;membrane protein proteolysis;0.0129841013672093!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0129897953950801!GO:0046365;monosaccharide catabolic process;0.0130003996854809!GO:0050681;androgen receptor binding;0.0132457202839523!GO:0000922;spindle pole;0.0132457202839523!GO:0006338;chromatin remodeling;0.0133898102787446!GO:0019318;hexose metabolic process;0.0134331301723497!GO:0000228;nuclear chromosome;0.0135144268582431!GO:0006405;RNA export from nucleus;0.0136290980706924!GO:0016584;nucleosome positioning;0.0141066365449108!GO:0000082;G1/S transition of mitotic cell cycle;0.0151776087804356!GO:0006779;porphyrin biosynthetic process;0.0155987842862822!GO:0033014;tetrapyrrole biosynthetic process;0.0155987842862822!GO:0044438;microbody part;0.0156494506353658!GO:0044439;peroxisomal part;0.0156494506353658!GO:0008234;cysteine-type peptidase activity;0.015651402842343!GO:0009303;rRNA transcription;0.015651402842343!GO:0005975;carbohydrate metabolic process;0.0159773760129899!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.0159773760129899!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0161570260162092!GO:0008601;protein phosphatase type 2A regulator activity;0.0162988921948672!GO:0009112;nucleobase metabolic process;0.0162988921948672!GO:0005862;muscle thin filament tropomyosin;0.0164783613903082!GO:0046164;alcohol catabolic process;0.0165626092675158!GO:0008139;nuclear localization sequence binding;0.0166906873422038!GO:0008203;cholesterol metabolic process;0.016888958989945!GO:0030125;clathrin vesicle coat;0.016888958989945!GO:0030665;clathrin coated vesicle membrane;0.016888958989945!GO:0019206;nucleoside kinase activity;0.0168910710574456!GO:0006284;base-excision repair;0.0169762870678244!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0171963722091153!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0171963722091153!GO:0030384;phosphoinositide metabolic process;0.0171963722091153!GO:0016481;negative regulation of transcription;0.0171963722091153!GO:0008017;microtubule binding;0.0175197163268793!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0176808444450485!GO:0009262;deoxyribonucleotide metabolic process;0.0178220453469893!GO:0000178;exosome (RNase complex);0.0180602973607124!GO:0043130;ubiquitin binding;0.0181556793366668!GO:0032182;small conjugating protein binding;0.0181556793366668!GO:0045045;secretory pathway;0.0181821677009402!GO:0000792;heterochromatin;0.0183116651786057!GO:0015036;disulfide oxidoreductase activity;0.0187273451784058!GO:0043241;protein complex disassembly;0.0187813004653151!GO:0051098;regulation of binding;0.0187813004653151!GO:0043631;RNA polyadenylation;0.0190819604998226!GO:0000097;sulfur amino acid biosynthetic process;0.0194319955757908!GO:0031901;early endosome membrane;0.0199620087671953!GO:0042168;heme metabolic process;0.0206048887214975!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0206061234778245!GO:0019320;hexose catabolic process;0.0207240198051042!GO:0016776;phosphotransferase activity, phosphate group as acceptor;0.0207661136174329!GO:0008097;5S rRNA binding;0.0208544014411771!GO:0030145;manganese ion binding;0.0209318445418806!GO:0000910;cytokinesis;0.0211263362808476!GO:0006749;glutathione metabolic process;0.0217500234461969!GO:0032981;mitochondrial respiratory chain complex I assembly;0.022008756369272!GO:0010257;NADH dehydrogenase complex assembly;0.022008756369272!GO:0033108;mitochondrial respiratory chain complex assembly;0.022008756369272!GO:0003756;protein disulfide isomerase activity;0.0225813954317648!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0225813954317648!GO:0031903;microbody membrane;0.0225946247871103!GO:0005778;peroxisomal membrane;0.0225946247871103!GO:0000209;protein polyubiquitination;0.0226749792535182!GO:0007050;cell cycle arrest;0.0234850841291951!GO:0000118;histone deacetylase complex;0.0234850841291951!GO:0000159;protein phosphatase type 2A complex;0.0235071508767813!GO:0051128;regulation of cellular component organization and biogenesis;0.0239693883843362!GO:0043596;nuclear replication fork;0.0244003356699217!GO:0016791;phosphoric monoester hydrolase activity;0.0244208672186157!GO:0004518;nuclease activity;0.024506217606772!GO:0006730;one-carbon compound metabolic process;0.0249269496119287!GO:0035035;histone acetyltransferase binding;0.0253173559348495!GO:0006221;pyrimidine nucleotide biosynthetic process;0.0259754304278011!GO:0050790;regulation of catalytic activity;0.0269095410917895!GO:0006767;water-soluble vitamin metabolic process;0.027052195888582!GO:0008652;amino acid biosynthetic process;0.0279114055656899!GO:0005875;microtubule associated complex;0.0281204898449059!GO:0005938;cell cortex;0.0283924988341908!GO:0007041;lysosomal transport;0.0284238539632343!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0285408123192351!GO:0006376;mRNA splice site selection;0.0288910486340241!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0288910486340241!GO:0005784;translocon complex;0.0289176871905991!GO:0030100;regulation of endocytosis;0.0295202979473045!GO:0006497;protein amino acid lipidation;0.029723352163612!GO:0009124;nucleoside monophosphate biosynthetic process;0.0298871895471192!GO:0009123;nucleoside monophosphate metabolic process;0.0298871895471192!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0299033660092983!GO:0004192;cathepsin D activity;0.0299769863754055!GO:0004532;exoribonuclease activity;0.0301011867462487!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0301011867462487!GO:0003923;GPI-anchor transamidase activity;0.0312908663109221!GO:0016255;attachment of GPI anchor to protein;0.0312908663109221!GO:0042765;GPI-anchor transamidase complex;0.0312908663109221!GO:0000287;magnesium ion binding;0.0312908663109221!GO:0008538;proteasome activator activity;0.0316123012206076!GO:0042158;lipoprotein biosynthetic process;0.0316123012206076!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0331273303251245!GO:0005777;peroxisome;0.0332120610786011!GO:0042579;microbody;0.0332120610786011!GO:0031371;ubiquitin conjugating enzyme complex;0.0332120610786011!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0334642874259506!GO:0016301;kinase activity;0.0334992870697417!GO:0032259;methylation;0.0336650708216002!GO:0030508;thiol-disulfide exchange intermediate activity;0.0339601284186622!GO:0042026;protein refolding;0.0342213124717391!GO:0050811;GABA receptor binding;0.0346945284072531!GO:0033673;negative regulation of kinase activity;0.0347599142708362!GO:0006469;negative regulation of protein kinase activity;0.0347599142708362!GO:0044454;nuclear chromosome part;0.034887373617042!GO:0050178;phenylpyruvate tautomerase activity;0.0349977624185769!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.0350974984525472!GO:0006897;endocytosis;0.0354859038692099!GO:0010324;membrane invagination;0.0354859038692099!GO:0043414;biopolymer methylation;0.0356821852536536!GO:0030149;sphingolipid catabolic process;0.0369666732993024!GO:0006275;regulation of DNA replication;0.0371345413445195!GO:0004003;ATP-dependent DNA helicase activity;0.0381629429575611!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0382742868221353!GO:0045039;protein import into mitochondrial inner membrane;0.0382742868221353!GO:0009451;RNA modification;0.0384956077018282!GO:0004300;enoyl-CoA hydratase activity;0.0390321295230152!GO:0004674;protein serine/threonine kinase activity;0.0392315873328606!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0396150805349903!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0397837033335405!GO:0033559;unsaturated fatty acid metabolic process;0.0400062928036528!GO:0006636;unsaturated fatty acid biosynthetic process;0.0400062928036528!GO:0005663;DNA replication factor C complex;0.0404796928951128!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0412063664049788!GO:0016615;malate dehydrogenase activity;0.0412063664049788!GO:0005669;transcription factor TFIID complex;0.0416866780352565!GO:0004197;cysteine-type endopeptidase activity;0.0421479556261785!GO:0030032;lamellipodium biogenesis;0.0421479556261785!GO:0030911;TPR domain binding;0.0425407854831474!GO:0051348;negative regulation of transferase activity;0.0426234030164273!GO:0046128;purine ribonucleoside metabolic process;0.0426853558534454!GO:0042278;purine nucleoside metabolic process;0.0426853558534454!GO:0016407;acetyltransferase activity;0.0431155706953084!GO:0046488;phosphatidylinositol metabolic process;0.0435464607463546!GO:0006739;NADP metabolic process;0.0435872665249487!GO:0009132;nucleoside diphosphate metabolic process;0.0437574444989949!GO:0051101;regulation of DNA binding;0.0440198224446496!GO:0009066;aspartate family amino acid metabolic process;0.0440980001797076!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0447237912857907!GO:0006506;GPI anchor biosynthetic process;0.0451677456933988!GO:0006790;sulfur metabolic process;0.0462025137556404!GO:0017134;fibroblast growth factor binding;0.046214485331607!GO:0031577;spindle checkpoint;0.0462639944092956!GO:0035267;NuA4 histone acetyltransferase complex;0.0462639944092956!GO:0030262;apoptotic nuclear changes;0.0469340995083221!GO:0006661;phosphatidylinositol biosynthetic process;0.0472684191149752!GO:0016835;carbon-oxygen lyase activity;0.0474115556278668!GO:0000086;G2/M transition of mitotic cell cycle;0.0478581654090819!GO:0000070;mitotic sister chromatid segregation;0.047943278719321!GO:0046982;protein heterodimerization activity;0.047943278719321!GO:0000725;recombinational repair;0.047943278719321!GO:0000724;double-strand break repair via homologous recombination;0.047943278719321!GO:0006635;fatty acid beta-oxidation;0.0480673354157633!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0480673354157633!GO:0006783;heme biosynthetic process;0.0484284896024887!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0485507495667628!GO:0042769;DNA damage response, detection of DNA damage;0.0492113862179789 | |||
|sample_id=11215 | |sample_id=11215 | ||
|sample_note=machine failed, remainder reloaded, low amount | |sample_note=machine failed, remainder reloaded, low amount | ||
| Line 75: | Line 104: | ||
|sample_tissue=retina | |sample_tissue=retina | ||
|top_motifs=NKX2-1,4:2.68317645028;PAX1,9:1.85433246768;CRX:1.75702217167;ESRRA:1.6838650169;NANOG:1.67452245044;EBF1:1.66539599543;HOX{A6,A7,B6,B7}:1.49704385594;PAX8:1.3299923239;NFY{A,B,C}:1.24655033932;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.23478065362;ADNP_IRX_SIX_ZHX:1.18736604179;MYOD1:1.09100101281;CDC5L:1.04346009803;E2F1..5:1.01177980321;PPARG:1.00937560671;PBX1:0.929655727237;VSX1,2:0.927197660876;STAT5{A,B}:0.904081302685;GTF2A1,2:0.878071322124;SP1:0.875365046466;NR3C1:0.86374905631;RXR{A,B,G}:0.841386245937;CDX1,2,4:0.797011398923;GFI1:0.794842726016;HSF1,2:0.785436994354;TLX1..3_NFIC{dimer}:0.784789901449;EN1,2:0.768002478836;RBPJ:0.767926873718;bHLH_family:0.758738698841;ONECUT1,2:0.752461698965;TFDP1:0.741096955397;ZIC1..3:0.718867038084;SREBF1,2:0.67696963461;PRRX1,2:0.671821526867;T:0.6669612529;ARID5B:0.630688325092;NKX6-1,2:0.622106808567;ZNF148:0.601030879217;ZNF423:0.595999626665;PDX1:0.595505274504;ZNF143:0.54963875912;PAX6:0.544763709867;NR5A1,2:0.540813346855;NFIL3:0.530058741388;HOX{A5,B5}:0.502593699723;RFX1:0.491703282934;TEAD1:0.469799411106;HAND1,2:0.44694050897;XCPE1{core}:0.433978737367;NRF1:0.422115667987;SOX17:0.415072607941;PAX5:0.405793907114;OCT4_SOX2{dimer}:0.404313348249;SOX{8,9,10}:0.384100204881;ZEB1:0.376264851523;HNF4A_NR2F1,2:0.374130958425;HOXA9_MEIS1:0.367928934991;GCM1,2:0.355729710196;LHX3,4:0.354280053386;NKX2-2,8:0.351065673765;JUN:0.342281233476;TEF:0.334625028874;TFAP4:0.327857543952;LMO2:0.286541062927;SOX2:0.284954500362;TBP:0.283940882625;POU1F1:0.27820712888;NKX2-3_NKX2-5:0.267097622653;YY1:0.266350011772;SNAI1..3:0.250445495711;HOX{A4,D4}:0.248792809535;FOXL1:0.239151732927;MYB:0.232818998675;TFAP2{A,C}:0.226414011581;FOSL2:0.225908336025;GFI1B:0.221365900424;TP53:0.204945941965;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.18484745497;IKZF2:0.181788856956;POU5F1:0.165768495073;LEF1_TCF7_TCF7L1,2:0.165067094066;FOXQ1:0.15783857129;FOXM1:0.154235835123;PATZ1:0.154007201084;MYBL2:0.153776930887;HIC1:0.153768832368;NKX3-2:0.135939195073;AIRE:0.131817022386;POU3F1..4:0.100481398888;MEF2{A,B,C,D}:0.0829848507459;EVI1:0.0819193884061;ELK1,4_GABP{A,B1}:0.0433517710345;TFAP2B:0.0390086610038;FOS_FOS{B,L1}_JUN{B,D}:0.0352271463445;FOX{I1,J2}:0.0284938063655;GTF2I:0.02553303692;ZFP161:0.0180976339815;BACH2:0.0112576075557;NFE2L2:0.0111148083271;HES1:0.00966494472347;RORA:-0.0106282918323;NFE2:-0.0197011627811;ALX1:-0.0256887922916;RXRA_VDR{dimer}:-0.0292538846424;HNF1A:-0.0363157716683;MAZ:-0.0364982445493;NR6A1:-0.0376567411042;KLF4:-0.0444375376441;POU2F1..3:-0.0466829243915;NR1H4:-0.0582032574242;EGR1..3:-0.0697737685958;SMAD1..7,9:-0.0842100826019;RREB1:-0.102342418306;TAL1_TCF{3,4,12}:-0.102888914012;NFATC1..3:-0.104875815153;GLI1..3:-0.10749045517;FOX{F1,F2,J1}:-0.110778479252;UFEwm:-0.119185836259;TBX4,5:-0.148534230901;RFX2..5_RFXANK_RFXAP:-0.169619454999;XBP1:-0.179550853735;PAX4:-0.18549382308;CUX2:-0.214758937915;FOXP1:-0.222996931222;BREu{core}:-0.223131786929;ZBTB6:-0.232462954677;NHLH1,2:-0.236175428713;PRDM1:-0.258211402836;PITX1..3:-0.260200183223;STAT1,3:-0.276321786149;SOX5:-0.300729193203;SPZ1:-0.301722571596;FOXD3:-0.304189086247;REST:-0.317515635566;IKZF1:-0.322489598743;GATA6:-0.329996073198;ALX4:-0.338222037018;SRF:-0.395515389693;MTE{core}:-0.4117048674;FOXA2:-0.435964513355;TFCP2:-0.441231373874;HLF:-0.469489055906;RUNX1..3:-0.470554303473;FOXP3:-0.473646017052;MTF1:-0.476035283297;TOPORS:-0.496138532071;GZF1:-0.499762422767;NFIX:-0.51138382727;MZF1:-0.542810671834;NFKB1_REL_RELA:-0.544241363964;SPIB:-0.547109502005;PAX3,7:-0.560015412524;FOXO1,3,4:-0.560193725736;MYFfamily:-0.57044594724;CREB1:-0.572576731942;AHR_ARNT_ARNT2:-0.580948054131;TGIF1:-0.580972792706;POU6F1:-0.601619445303;ATF2:-0.648272715273;GATA4:-0.652065377467;HMGA1,2:-0.659249741076;HIF1A:-0.694305625788;SPI1:-0.708441363097;NFE2L1:-0.709614001274;FOX{D1,D2}:-0.712320700153;EP300:-0.716806165636;CEBPA,B_DDIT3:-0.73209883495;NKX3-1:-0.73302979293;ATF5_CREB3:-0.747630220243;DBP:-0.754201825132;ATF6:-0.77717858544;ETS1,2:-0.780469804463;ATF4:-0.788456915466;STAT2,4,6:-0.798557608743;IRF1,2:-0.801514162411;PAX2:-0.809106690962;MED-1{core}:-0.826862281966;BPTF:-0.840741963843;ELF1,2,4:-0.851075284778;ZBTB16:-0.860053907783;HMX1:-0.894181617905;ZNF384:-0.897520315789;IRF7:-0.898838103557;DMAP1_NCOR{1,2}_SMARC:-0.936356582474;FOXN1:-0.952215277286;HBP1_HMGB_SSRP1_UBTF:-0.95276585209;AR:-0.967967034195;ESR1:-1.01278002399;NANOG{mouse}:-1.31112053793;MAFB:-1.32474932186;TLX2:-1.48692943529;ZNF238:-1.53866817527 | |top_motifs=NKX2-1,4:2.68317645028;PAX1,9:1.85433246768;CRX:1.75702217167;ESRRA:1.6838650169;NANOG:1.67452245044;EBF1:1.66539599543;HOX{A6,A7,B6,B7}:1.49704385594;PAX8:1.3299923239;NFY{A,B,C}:1.24655033932;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.23478065362;ADNP_IRX_SIX_ZHX:1.18736604179;MYOD1:1.09100101281;CDC5L:1.04346009803;E2F1..5:1.01177980321;PPARG:1.00937560671;PBX1:0.929655727237;VSX1,2:0.927197660876;STAT5{A,B}:0.904081302685;GTF2A1,2:0.878071322124;SP1:0.875365046466;NR3C1:0.86374905631;RXR{A,B,G}:0.841386245937;CDX1,2,4:0.797011398923;GFI1:0.794842726016;HSF1,2:0.785436994354;TLX1..3_NFIC{dimer}:0.784789901449;EN1,2:0.768002478836;RBPJ:0.767926873718;bHLH_family:0.758738698841;ONECUT1,2:0.752461698965;TFDP1:0.741096955397;ZIC1..3:0.718867038084;SREBF1,2:0.67696963461;PRRX1,2:0.671821526867;T:0.6669612529;ARID5B:0.630688325092;NKX6-1,2:0.622106808567;ZNF148:0.601030879217;ZNF423:0.595999626665;PDX1:0.595505274504;ZNF143:0.54963875912;PAX6:0.544763709867;NR5A1,2:0.540813346855;NFIL3:0.530058741388;HOX{A5,B5}:0.502593699723;RFX1:0.491703282934;TEAD1:0.469799411106;HAND1,2:0.44694050897;XCPE1{core}:0.433978737367;NRF1:0.422115667987;SOX17:0.415072607941;PAX5:0.405793907114;OCT4_SOX2{dimer}:0.404313348249;SOX{8,9,10}:0.384100204881;ZEB1:0.376264851523;HNF4A_NR2F1,2:0.374130958425;HOXA9_MEIS1:0.367928934991;GCM1,2:0.355729710196;LHX3,4:0.354280053386;NKX2-2,8:0.351065673765;JUN:0.342281233476;TEF:0.334625028874;TFAP4:0.327857543952;LMO2:0.286541062927;SOX2:0.284954500362;TBP:0.283940882625;POU1F1:0.27820712888;NKX2-3_NKX2-5:0.267097622653;YY1:0.266350011772;SNAI1..3:0.250445495711;HOX{A4,D4}:0.248792809535;FOXL1:0.239151732927;MYB:0.232818998675;TFAP2{A,C}:0.226414011581;FOSL2:0.225908336025;GFI1B:0.221365900424;TP53:0.204945941965;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.18484745497;IKZF2:0.181788856956;POU5F1:0.165768495073;LEF1_TCF7_TCF7L1,2:0.165067094066;FOXQ1:0.15783857129;FOXM1:0.154235835123;PATZ1:0.154007201084;MYBL2:0.153776930887;HIC1:0.153768832368;NKX3-2:0.135939195073;AIRE:0.131817022386;POU3F1..4:0.100481398888;MEF2{A,B,C,D}:0.0829848507459;EVI1:0.0819193884061;ELK1,4_GABP{A,B1}:0.0433517710345;TFAP2B:0.0390086610038;FOS_FOS{B,L1}_JUN{B,D}:0.0352271463445;FOX{I1,J2}:0.0284938063655;GTF2I:0.02553303692;ZFP161:0.0180976339815;BACH2:0.0112576075557;NFE2L2:0.0111148083271;HES1:0.00966494472347;RORA:-0.0106282918323;NFE2:-0.0197011627811;ALX1:-0.0256887922916;RXRA_VDR{dimer}:-0.0292538846424;HNF1A:-0.0363157716683;MAZ:-0.0364982445493;NR6A1:-0.0376567411042;KLF4:-0.0444375376441;POU2F1..3:-0.0466829243915;NR1H4:-0.0582032574242;EGR1..3:-0.0697737685958;SMAD1..7,9:-0.0842100826019;RREB1:-0.102342418306;TAL1_TCF{3,4,12}:-0.102888914012;NFATC1..3:-0.104875815153;GLI1..3:-0.10749045517;FOX{F1,F2,J1}:-0.110778479252;UFEwm:-0.119185836259;TBX4,5:-0.148534230901;RFX2..5_RFXANK_RFXAP:-0.169619454999;XBP1:-0.179550853735;PAX4:-0.18549382308;CUX2:-0.214758937915;FOXP1:-0.222996931222;BREu{core}:-0.223131786929;ZBTB6:-0.232462954677;NHLH1,2:-0.236175428713;PRDM1:-0.258211402836;PITX1..3:-0.260200183223;STAT1,3:-0.276321786149;SOX5:-0.300729193203;SPZ1:-0.301722571596;FOXD3:-0.304189086247;REST:-0.317515635566;IKZF1:-0.322489598743;GATA6:-0.329996073198;ALX4:-0.338222037018;SRF:-0.395515389693;MTE{core}:-0.4117048674;FOXA2:-0.435964513355;TFCP2:-0.441231373874;HLF:-0.469489055906;RUNX1..3:-0.470554303473;FOXP3:-0.473646017052;MTF1:-0.476035283297;TOPORS:-0.496138532071;GZF1:-0.499762422767;NFIX:-0.51138382727;MZF1:-0.542810671834;NFKB1_REL_RELA:-0.544241363964;SPIB:-0.547109502005;PAX3,7:-0.560015412524;FOXO1,3,4:-0.560193725736;MYFfamily:-0.57044594724;CREB1:-0.572576731942;AHR_ARNT_ARNT2:-0.580948054131;TGIF1:-0.580972792706;POU6F1:-0.601619445303;ATF2:-0.648272715273;GATA4:-0.652065377467;HMGA1,2:-0.659249741076;HIF1A:-0.694305625788;SPI1:-0.708441363097;NFE2L1:-0.709614001274;FOX{D1,D2}:-0.712320700153;EP300:-0.716806165636;CEBPA,B_DDIT3:-0.73209883495;NKX3-1:-0.73302979293;ATF5_CREB3:-0.747630220243;DBP:-0.754201825132;ATF6:-0.77717858544;ETS1,2:-0.780469804463;ATF4:-0.788456915466;STAT2,4,6:-0.798557608743;IRF1,2:-0.801514162411;PAX2:-0.809106690962;MED-1{core}:-0.826862281966;BPTF:-0.840741963843;ELF1,2,4:-0.851075284778;ZBTB16:-0.860053907783;HMX1:-0.894181617905;ZNF384:-0.897520315789;IRF7:-0.898838103557;DMAP1_NCOR{1,2}_SMARC:-0.936356582474;FOXN1:-0.952215277286;HBP1_HMGB_SSRP1_UBTF:-0.95276585209;AR:-0.967967034195;ESR1:-1.01278002399;NANOG{mouse}:-1.31112053793;MAFB:-1.32474932186;TLX2:-1.48692943529;ZNF238:-1.53866817527 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11215-116A9;search_select_hide=table117:FF:11215-116A9 | |||
}} | }} | ||
Latest revision as of 16:24, 3 June 2020
| Name: | Retinal Pigment Epithelial Cells, donor0 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs10842 |
| Sample type: | primary cells |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7 |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10842
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10842
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.285 |
| 10 | 10 | 0.00823 |
| 100 | 100 | 0.266 |
| 101 | 101 | 0.364 |
| 102 | 102 | 0.419 |
| 103 | 103 | 0.932 |
| 104 | 104 | 0.63 |
| 105 | 105 | 0.407 |
| 106 | 106 | 0.00172 |
| 107 | 107 | 0.435 |
| 108 | 108 | 0.936 |
| 109 | 109 | 0.369 |
| 11 | 11 | 0.851 |
| 110 | 110 | 0.788 |
| 111 | 111 | 0.0385 |
| 112 | 112 | 0.00104 |
| 113 | 113 | 0.0301 |
| 114 | 114 | 0.0429 |
| 115 | 115 | 0.88 |
| 116 | 116 | 0.716 |
| 117 | 117 | 0.0329 |
| 118 | 118 | 0.575 |
| 119 | 119 | 0.145 |
| 12 | 12 | 0.671 |
| 120 | 120 | 0.635 |
| 121 | 121 | 0.751 |
| 122 | 122 | 0.447 |
| 123 | 123 | 0.0709 |
| 124 | 124 | 0.271 |
| 125 | 125 | 0.893 |
| 126 | 126 | 0.32 |
| 127 | 127 | 0.933 |
| 128 | 128 | 0.168 |
| 129 | 129 | 0.604 |
| 13 | 13 | 0.485 |
| 130 | 130 | 0.0101 |
| 131 | 131 | 0.116 |
| 132 | 132 | 0.975 |
| 133 | 133 | 0.0729 |
| 134 | 134 | 0.783 |
| 135 | 135 | 0.0313 |
| 136 | 136 | 0.143 |
| 137 | 137 | 0.245 |
| 138 | 138 | 2.62229e-4 |
| 139 | 139 | 0.00773 |
| 14 | 14 | 0.571 |
| 140 | 140 | 0.0287 |
| 141 | 141 | 0.232 |
| 142 | 142 | 0.734 |
| 143 | 143 | 0.151 |
| 144 | 144 | 0.249 |
| 145 | 145 | 0.386 |
| 146 | 146 | 0.902 |
| 147 | 147 | 0.253 |
| 148 | 148 | 0.111 |
| 149 | 149 | 0.904 |
| 15 | 15 | 0.794 |
| 150 | 150 | 0.48 |
| 151 | 151 | 0.554 |
| 152 | 152 | 0.997 |
| 153 | 153 | 0.469 |
| 154 | 154 | 0.38 |
| 155 | 155 | 0.237 |
| 156 | 156 | 0.35 |
| 157 | 157 | 0.0557 |
| 158 | 158 | 0.0996 |
| 159 | 159 | 0.651 |
| 16 | 16 | 0.685 |
| 160 | 160 | 0.894 |
| 161 | 161 | 0.877 |
| 162 | 162 | 0.253 |
| 163 | 163 | 0.649 |
| 164 | 164 | 0.0287 |
| 165 | 165 | 0.0987 |
| 166 | 166 | 0.321 |
| 167 | 167 | 0.669 |
| 168 | 168 | 0.238 |
| 169 | 169 | 0.383 |
| 17 | 17 | 0.878 |
| 18 | 18 | 0.0523 |
| 19 | 19 | 0.419 |
| 2 | 2 | 0.476 |
| 20 | 20 | 0.709 |
| 21 | 21 | 0.416 |
| 22 | 22 | 0.605 |
| 23 | 23 | 0.0398 |
| 24 | 24 | 0.421 |
| 25 | 25 | 0.465 |
| 26 | 26 | 0.752 |
| 27 | 27 | 0.841 |
| 28 | 28 | 0.597 |
| 29 | 29 | 0.946 |
| 3 | 3 | 0.023 |
| 30 | 30 | 0.0744 |
| 31 | 31 | 0.748 |
| 32 | 32 | 0.007 |
| 33 | 33 | 0.405 |
| 34 | 34 | 0.601 |
| 35 | 35 | 0.262 |
| 36 | 36 | 0.904 |
| 37 | 37 | 0.411 |
| 38 | 38 | 0.84 |
| 39 | 39 | 0.848 |
| 4 | 4 | 0.863 |
| 40 | 40 | 0.0343 |
| 41 | 41 | 0.306 |
| 42 | 42 | 0.171 |
| 43 | 43 | 0.094 |
| 44 | 44 | 0.839 |
| 45 | 45 | 0.381 |
| 46 | 46 | 0.026 |
| 47 | 47 | 0.819 |
| 48 | 48 | 0.971 |
| 49 | 49 | 0.317 |
| 5 | 5 | 0.123 |
| 50 | 50 | 0.352 |
| 51 | 51 | 0.649 |
| 52 | 52 | 0.656 |
| 53 | 53 | 0.592 |
| 54 | 54 | 0.88 |
| 55 | 55 | 0.12 |
| 56 | 56 | 0.827 |
| 57 | 57 | 0.682 |
| 58 | 58 | 0.00305 |
| 59 | 59 | 0.345 |
| 6 | 6 | 0.765 |
| 60 | 60 | 0.012 |
| 61 | 61 | 0.888 |
| 62 | 62 | 0.00225 |
| 63 | 63 | 0.125 |
| 64 | 64 | 0.416 |
| 65 | 65 | 0.262 |
| 66 | 66 | 0.0252 |
| 67 | 67 | 0.958 |
| 68 | 68 | 0.77 |
| 69 | 69 | 0.0649 |
| 7 | 7 | 0.961 |
| 70 | 70 | 0.0757 |
| 71 | 71 | 0.0954 |
| 72 | 72 | 0.182 |
| 73 | 73 | 0.427 |
| 74 | 74 | 0.243 |
| 75 | 75 | 0.283 |
| 76 | 76 | 0.14 |
| 77 | 77 | 0.307 |
| 78 | 78 | 0.599 |
| 79 | 79 | 0.0306 |
| 8 | 8 | 0.707 |
| 80 | 80 | 0.157 |
| 81 | 81 | 0.209 |
| 82 | 82 | 0.0841 |
| 83 | 83 | 0.0389 |
| 84 | 84 | 0.921 |
| 85 | 85 | 0.0442 |
| 86 | 86 | 0.187 |
| 87 | 87 | 0.147 |
| 88 | 88 | 0.735 |
| 89 | 89 | 0.972 |
| 9 | 9 | 0.268 |
| 90 | 90 | 0.714 |
| 91 | 91 | 0.0219 |
| 92 | 92 | 0.0174 |
| 93 | 93 | 0.635 |
| 94 | 94 | 0.0768 |
| 95 | 95 | 0.374 |
| 96 | 96 | 0.45 |
| 97 | 97 | 0.975 |
| 98 | 98 | 0.103 |
| 99 | 99 | 0.0502 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs10842
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000158 human retinal pigment epithelial cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000325 (stuff accumulating cell)
0000147 (pigment cell)
0000255 (eukaryotic cell)
0000149 (visual pigment cell)
0002586 (retinal pigment epithelial cell)
UBERON: Anatomy
0000468 (multi-cellular organism)
0000966 (retina)
0000970 (eye)
0000019 (camera-type eye)
0000483 (epithelium)
0000033 (head)
0000479 (tissue)
0004121 (ectoderm-derived structure)
0000064 (organ part)
0010314 (structure with developmental contribution from neural crest)
0000047 (simple eye)
0000062 (organ)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000063 (organ segment)
0004923 (organ component layer)
0001444 (subdivision of head)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000119 (cell layer)
0005388 (photoreceptor array)
0000020 (sense organ)
0010371 (ecto-epithelium)
0007625 (pigment epithelium of eye)
0001781 (layer of retina)
0001032 (sensory system)
0010317 (germ layer / neural crest derived structure)
0001782 (pigmented layer of retina)
0004088 (ocular region)
0000153 (anterior region of body)
0007811 (craniocervical region)
0002104 (visual system)
0001802 (posterior segment of eyeball)
0004456 (entire sense organ system)
0001456 (face)
0010230 (eyeball of camera-type eye)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000158 (human retinal pigment epithelial cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA
