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{{f5samples
{{f5samples
|ancestors_in_anatomy_facet=UBERON:0000061,UBERON:0000062,UBERON:0000465,UBERON:0000467,UBERON:0000468,UBERON:0000479,UBERON:0000480,UBERON:0000922,UBERON:0000923,UBERON:0000926,UBERON:0001062,UBERON:0001434,UBERON:0001474,UBERON:0002050,UBERON:0002193,UBERON:0002204,UBERON:0002371,UBERON:0002384,UBERON:0002390,UBERON:0002405,UBERON:0002532,UBERON:0004120,UBERON:0004765,UBERON:0005423
|DRA_sample_Accession=CAGE@SAMD00005152
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000004,CL:0000012,CL:0000034,CL:0000037,CL:0000040,CL:0000048,CL:0000049,CL:0000063,CL:0000134,CL:0000144,CL:0000219,CL:0000235,CL:0000255,CL:0000548,CL:0000557,CL:0000559,CL:0000566,CL:0000576,CL:0000723,CL:0000738,CL:0000763,CL:0000766,CL:0000837,CL:0000839,CL:0000988,CL:0001012,CL:0002009,CL:0002031,CL:0002032,CL:0002087,CL:0002194,CL:0002320,CL:0002371
|DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005152
|accession_numbers=CAGE;DRX008324;DRR009196;DRZ000621;DRZ002006;DRZ011971;DRZ013356
|accession_numbers_RNASeq=sRNA-Seq;DRX037086;DRR041452;DRZ007094
|ancestors_in_anatomy_facet=
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0000255,CL:0000235
|ancestors_in_disease_facet=
|ancestors_in_disease_facet=
|ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000086
|comment=
|comment=
|created_by=
|created_by=
|creation_date=
|creation_date=
|data_phase=2
|datafreeze_phase=2
|def=
|def=
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!2.71!510.99!PLEK;;chr11:47400078..47400106,-!p1@SPI1!2.51!320.15!SPI1;;chr12:54778471..54778528,-!p1@ZNF385A!2.35!220.72!ZNF385A;;chr11:47279504..47279563,+!p1@NR1H3!2.10!271.55!NR1H3;;chr11:47400062..47400077,-!p2@SPI1!2.02!102.70!SPI1;;chr7:115670804..115670825,-!p1@TFEC!1.98!94.08!TFEC;;chr16:85932760..85932775,+!p1@IRF8!1.86!70.90!IRF8;;chr20:39317868..39317884,-!p1@MAFB!1.71!561.53!MAFB;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.70!49.20!ZBED1;;chr10:31288398..31288455,-!p2@ZNF438!1.63!47.86!ZNF438;;chr10:64576105..64576133,-!p1@EGR2!1.54!67.48!EGR2;;chr11:47399996..47400014,-!p4@SPI1!1.53!32.85!SPI1;;chr19:33793430..33793447,-!p1@CEBPA!1.52!129.46!CEBPA;;chr7:137620684..137620711,-!p4@CREB3L2!1.51!31.66!CREB3L2;;chr7:128577972..128578047,+!p1@IRF5!1.48!45.33!IRF5;;chr11:47399947..47399961,-!p3@SPI1!1.47!28.39!SPI1;;chr7:137620650..137620677,-!p3@CREB3L2!1.43!25.86!CREB3L2;;chr7:50344289..50344323,+!p1@IKZF1!1.42!25.27!IKZF1;;chr11:47400032..47400043,-!p5@SPI1!1.40!23.93!SPI1;;chr10:51572408..51572454,+!p3@NCOA4!1.39!132.88!NCOA4;;chr14:75988771..75988826,+!p1@BATF!1.30!25.27!BATF;;chr10:31288370..31288393,-!p3@ZNF438!1.29!18.58!ZNF438;;chr3:12330560..12330579,+!p1@PPARG!1.27!20.21!PPARG;;chr11:47400045..47400060,-!p6@SPI1!1.27!17.69!SPI1;;chr2:68592394..68592405,+!p2@PLEK!1.22!15.46!PLEK;;chr2:145277640..145277771,-!p1@ZEB2!1.21!202.14!ZEB2;;chr8:72756063..72756125,-!p1@MSC!1.20!30.02!MSC;;chr2:145277882..145277967,-!p3@ZEB2!1.20!25.56!ZEB2;;chr3:69788576..69788648,+!p1@MITF!1.17!72.98!MITF;;chr5:71803177..71803255,-!p1@ZNF366!1.17!13.82!ZNF366;;chr12:26277956..26277980,-!p1@BHLHE41!1.13!45.33!BHLHE41;;chr16:79634624..79634642,-!p1@MAF!1.11!46.82!MAF;;chr7:50343634..50343717,+!p2@IKZF1!1.11!11.89!IKZF1;;chr12:12764995..12765017,+!p3@CREBL2!1.10!16.50!CREBL2;;chr19:13213662..13213686,-!p1@LYL1!1.09!16.65!LYL1;;chr19:50432132..50432217,+!p2@ATF5!1.04!11.89!ATF5;;chr6:44233252..44233296,-!p1@NFKBIE!0.98!85.76!NFKBIE;;chr19:13213954..13214021,-!p4@LYL1!0.98!8.62!LYL1;;chr2:70142232..70142251,+!p1@MXD1!0.96!47.12!MXD1;;chr10:64018918..64018936,+!p2@ZNF365!0.95!7.88!ZNF365;;chr17:40440481..40440550,+!p1@STAT5A!0.92!54.55!STAT5A;;chr12:12764947..12764986,+!p2@CREBL2!0.92!14.57!CREBL2;;chr19:13213704..13213726,-!p3@LYL1!0.91!9.51!LYL1;;chr1:158985493..158985535,+!p4@IFI16!0.88!10.40!IFI16;;chr12:26277929..26277955,-!p3@BHLHE41!0.88!9.51!BHLHE41;;chr1:23857698..23857733,-!p1@E2F2!0.86!11.74!E2F2;;chr6:144385698..144385742,-!p2@PLAGL1!0.85!7.58!PLAGL1;;chr11:47279568..47279577,+!p8@NR1H3!0.85!6.09!NR1H3;;chr1:212738742..212738755,+!p2@ATF3!0.84!5.95!ATF3;;chr11:128563948..128564003,+!p1@FLI1!0.83!75.36!FLI1;;chr10:51572339..51572376,+!p4@NCOA4!0.83!13.53!NCOA4;;chr7:149470641..149470694,-!p1@ZNF467!0.82!27.05!ZNF467;;chr18:6414884..6414942,-!p1@L3MBTL4!0.82!7.13!L3MBTL4;;chr11:47399920..47399931,-!p7@SPI1!0.82!5.65!SPI1;;chr7:139762641..139762768,-!p1@PARP12!0.79!77.44!PARP12;;chr9:137217986..137218049,+!p3@RXRA!0.78!15.61!RXRA;;chr20:48807456..48807475,+!p3@CEBPB!0.78!10.26!CEBPB;;chr8:53373491..53373506,-!p4@ST18!0.78!5.05!ST18;;chr2:231090433..231090469,+!p1@SP140!0.78!5.05!SP140;;chr19:42636586..42636607,-!p1@POU2F2!0.77!14.57!POU2F2;;chr16:79634595..79634620,-!p2@MAF!0.77!9.51!MAF;;chr1:212782094..212782109,+!p1@ATF3!0.76!144.32!ATF3;;chr2:145275162..145275202,-!p2@ZEB2!0.76!30.92!ZEB2;;chr10:94449703..94449718,+!p1@HHEX!0.76!20.07!HHEX;;chr11:65554528..65554546,+!p1@OVOL1!0.76!4.76!OVOL1;;chr7:115670792..115670797,-!p2@TFEC!0.76!4.76!TFEC;;chr5:142814364..142814381,-!p22@NR3C1!0.75!4.61!NR3C1;;chr8:72756213..72756243,-!p5@MSC!0.74!5.95!MSC;;chr19:10416315..10416333,-!p1@ZGLP1!0.74!4.46!ZGLP1;;chr13:41593425..41593480,-!p1@ELF1!0.73!30.92!ELF1;;chr2:113999360..113999386,-!p4@PAX8!0.73!4.31!PAX8;;chr18:52989031..52989079,-!p2@TCF4!0.72!10.85!TCF4;;chr19:35759824..35759891,+!p1@USF2!0.71!144.77!USF2;;chr2:231090344..231090361,-!p3@SP110!0.71!4.16!SP110;;chr11:47279491..47279502,+!p6@NR1H3!0.71!4.16!NR1H3;;chr12:26277817..26277863,-!p2@BHLHE41!0.69!5.50!BHLHE41;;chr16:88752889..88752921,-!p1@SNAI3!0.69!4.61!SNAI3;;chr6:41691289..41691312,-!p9@TFEB!0.69!3.86!TFEB;;chr16:31885093..31885165,+!p1@ZNF267!0.68!67.33!ZNF267;;chrX:131623044..131623089,-!p1@MBNL3!0.68!17.69!MBNL3;;chr19:36391434..36391450,-!p1@NFKBID!0.68!8.17!NFKBID;;chr20:48807351..48807384,+!p1@CEBPB!0.67!441.29!CEBPB;;chr3:48282587..48282603,+!p1@ZNF589!0.67!18.58!ZNF589;;chr6:35310395..35310410,+!p2@PPARD!0.67!16.35!PPARD;;chr12:54778351..54778378,-!p6@ZNF385A!0.67!3.72!ZNF385A;;chr2:122042770..122042785,-!p1@TFCP2L1!0.67!3.72!TFCP2L1;;chr8:72756267..72756296,-!p4@MSC!0.66!5.50!MSC;;chr6:152011654..152011682,+!p1@ESR1!0.66!3.57!ESR1;;chr3:129158715..129158766,-!p2@MBD4!0.65!38.94!MBD4;;chr6:35310363..35310382,+!p3@PPARD!0.65!14.71!PPARD;;chr19:926001..926046,+!p1@ARID3A!0.65!13.82!ARID3A;;chr10:35484804..35484902,+!p2@CREM!0.64!14.86!CREM;;chr8:116680215..116680245,-!p6@TRPS1!0.64!5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|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000235;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405
|ffid_belonging_in_development=CL:0000049,CL:0000134
|fonse_cell_line=
|fonse_cell_line=
|fonse_cell_line_closure=
|fonse_cell_line_closure=
Line 34: Line 44:
|fonse_treatment_closure=
|fonse_treatment_closure=
|has_quality=
|has_quality=
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Macrophage%2520-%2520monocyte%2520derived%252c%2520donor3.CNhs12003.11389-118C3.hg19.nobarcode.bam
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Macrophage%2520-%2520monocyte%2520derived%252c%2520donor3.CNhs12003.11389-118C3.hg19.ctss.bed.gz
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Macrophage%2520-%2520monocyte%2520derived%252c%2520donor3.CNhs12003.11389-118C3.hg19.nobarcode.rdna.fa.gz
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Macrophage%2520-%2520monocyte%2520derived%252c%2520donor3.CNhs12003.11389-118C3.hg38.nobarcode.bam
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Macrophage%2520-%2520monocyte%2520derived%252c%2520donor3.CNhs12003.11389-118C3.hg38.nobarcode.ctss.bed.gz
|id=FF:11389-118C3
|id=FF:11389-118C3
|is_a=EFO:0002091;;FF:0000002;;FF:0000086;;FF:0000210
|is_a=EFO:0002091;;FF:0000086
|is_obsolete=
|library_id=CNhs12003
|library_id_phase_based=2:CNhs12003
|microRNAs=
|microRNAs_nn=
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11389
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10006.GTTTCG.11389
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11389
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10006.GTTTCG.11389
|name=Macrophage - monocyte derived, donor3
|name=Macrophage - monocyte derived, donor3
|namespace=FANTOM5
|namespace=FANTOM5
Line 41: Line 65:
|profile_cagescan=,,,
|profile_cagescan=,,,
|profile_hcage=CNhs12003,LSID837,release011,COMPLETED
|profile_hcage=CNhs12003,LSID837,release011,COMPLETED
|profile_rnaseq=,,,
|profile_rnaseq=
|profile_srnaseq=SRhi10006,,,
|profile_srnaseq=SRhi10006,,,
|refex=http://refex.dbcls.jp/genelist.php?lang
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|rna_box=118
|rna_box=118
|rna_catalog_number=3H100-80-10
|rna_catalog_number=3H100-80-10
Line 55: Line 82:
|rna_tube_id=118C3
|rna_tube_id=118C3
|rna_weight_ug=10
|rna_weight_ug=10
|rnaseq_library_id=SRhi10006.GTTTCG
|sample_age=57
|sample_age=57
|sample_category=primary cells
|sample_cell_catalog=N/A
|sample_cell_catalog=N/A
|sample_cell_line=
|sample_cell_line=
Line 68: Line 97:
|sample_ethnicity=C
|sample_ethnicity=C
|sample_experimental_condition=
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;6.61437826985735e-230!GO:0005737;cytoplasm;2.13811042600577e-181!GO:0043227;membrane-bound organelle;1.44329972365346e-144!GO:0043231;intracellular membrane-bound organelle;2.56898123200932e-144!GO:0044444;cytoplasmic part;2.43548858239522e-139!GO:0043226;organelle;6.16578998249562e-133!GO:0043229;intracellular organelle;2.50727309510838e-132!GO:0044422;organelle part;1.80435833430857e-117!GO:0044446;intracellular organelle part;1.55629574413004e-115!GO:0032991;macromolecular complex;1.04178180298105e-78!GO:0044237;cellular metabolic process;4.71563156646811e-72!GO:0044238;primary metabolic process;6.36278843573428e-70!GO:0005739;mitochondrion;3.98273102354969e-65!GO:0031090;organelle membrane;1.59158884255157e-58!GO:0043170;macromolecule metabolic process;1.24813550686593e-57!GO:0005515;protein binding;5.16344740642607e-57!GO:0030529;ribonucleoprotein complex;6.13174471261408e-57!GO:0019538;protein metabolic process;9.74605766923878e-50!GO:0044428;nuclear part;3.17658417978952e-49!GO:0043233;organelle lumen;3.23610598138334e-49!GO:0031974;membrane-enclosed lumen;3.23610598138334e-49!GO:0003723;RNA binding;1.10265070115729e-48!GO:0033036;macromolecule localization;4.32542719880659e-48!GO:0015031;protein transport;3.67818519582532e-47!GO:0045184;establishment of protein localization;1.44825406966555e-46!GO:0044429;mitochondrial part;2.17285000528878e-46!GO:0044260;cellular macromolecule metabolic process;1.91749406149065e-45!GO:0008104;protein localization;2.96384322585976e-45!GO:0044267;cellular protein metabolic process;1.52865740660699e-44!GO:0031967;organelle envelope;2.81770019396205e-44!GO:0031975;envelope;7.22575858781376e-44!GO:0009058;biosynthetic process;2.12752695181474e-43!GO:0043234;protein complex;2.75807571901055e-43!GO:0006412;translation;1.10527872009869e-41!GO:0044249;cellular biosynthetic process;2.92878598260459e-38!GO:0005829;cytosol;1.4368811165268e-37!GO:0005634;nucleus;6.77669125151139e-37!GO:0016043;cellular component organization and biogenesis;1.8843075421353e-36!GO:0046907;intracellular transport;4.02788314831618e-36!GO:0009059;macromolecule biosynthetic process;1.97635478668241e-35!GO:0005840;ribosome;7.64762917957856e-34!GO:0005740;mitochondrial envelope;1.23709661789089e-32!GO:0006396;RNA processing;9.43647825430287e-32!GO:0031966;mitochondrial membrane;7.41991366069225e-31!GO:0006886;intracellular protein transport;8.86158784149019e-31!GO:0051649;establishment of cellular localization;2.28410077942435e-29!GO:0003735;structural constituent of ribosome;2.46347978196399e-29!GO:0019866;organelle inner membrane;9.63572794494663e-29!GO:0051641;cellular localization;1.27580599382933e-28!GO:0016071;mRNA metabolic process;1.73086295149419e-28!GO:0065003;macromolecular complex assembly;8.83143461146599e-28!GO:0005743;mitochondrial inner membrane;1.83005633663285e-26!GO:0031981;nuclear lumen;4.13337927213713e-26!GO:0006119;oxidative phosphorylation;4.13337927213713e-26!GO:0033279;ribosomal subunit;7.18495544628836e-26!GO:0008380;RNA splicing;2.33583925126762e-25!GO:0006996;organelle organization and biogenesis;7.71453007971365e-25!GO:0043283;biopolymer metabolic process;8.17810920101736e-25!GO:0006397;mRNA processing;5.20394032978626e-24!GO:0022607;cellular component assembly;6.26751381372968e-24!GO:0012505;endomembrane system;5.40828166646385e-22!GO:0000166;nucleotide binding;1.45874097719382e-21!GO:0051186;cofactor metabolic process;2.3548265446097e-21!GO:0048770;pigment granule;3.35648820675418e-21!GO:0042470;melanosome;3.35648820675418e-21!GO:0005773;vacuole;4.19077388048083e-21!GO:0044248;cellular catabolic process;3.3725148480727e-20!GO:0044265;cellular macromolecule catabolic process;3.38516586568199e-20!GO:0044455;mitochondrial membrane part;3.79710147922904e-20!GO:0006915;apoptosis;5.53911037733848e-20!GO:0012501;programmed cell death;7.63067123466479e-20!GO:0006259;DNA metabolic process;8.52231284377083e-20!GO:0016192;vesicle-mediated transport;2.09978667248275e-19!GO:0000323;lytic vacuole;2.68510628642043e-19!GO:0005764;lysosome;2.68510628642043e-19!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.08497713651551e-18!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.28620009807884e-18!GO:0005681;spliceosome;1.33827789431019e-18!GO:0008219;cell death;1.85902736759261e-18!GO:0016265;death;1.85902736759261e-18!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.46718256881988e-18!GO:0016462;pyrophosphatase activity;2.46718256881988e-18!GO:0016817;hydrolase activity, acting on acid anhydrides;3.36005876846502e-18!GO:0006732;coenzyme metabolic process;7.12496940379286e-18!GO:0005746;mitochondrial respiratory chain;1.60342581422914e-17!GO:0017111;nucleoside-triphosphatase activity;1.94205730860304e-17!GO:0017076;purine nucleotide binding;2.61815400443259e-17!GO:0044445;cytosolic part;3.03279759334659e-17!GO:0009057;macromolecule catabolic process;3.27524858197218e-17!GO:0043285;biopolymer catabolic process;4.11032129831788e-17!GO:0032553;ribonucleotide binding;4.11032129831788e-17!GO:0032555;purine ribonucleotide binding;4.11032129831788e-17!GO:0005783;endoplasmic reticulum;4.17509197100308e-17!GO:0005654;nucleoplasm;4.34204470332556e-17!GO:0007049;cell cycle;5.15139158446471e-17!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.63582551640208e-17!GO:0031980;mitochondrial lumen;1.0701902804062e-16!GO:0005759;mitochondrial matrix;1.0701902804062e-16!GO:0005794;Golgi apparatus;2.044270123079e-16!GO:0006512;ubiquitin cycle;3.06086675784064e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.09571506438829e-16!GO:0043228;non-membrane-bound organelle;3.29172704155258e-16!GO:0043232;intracellular non-membrane-bound organelle;3.29172704155258e-16!GO:0044432;endoplasmic reticulum part;3.79595098160265e-16!GO:0010467;gene expression;6.41337703360271e-16!GO:0016874;ligase activity;8.9811204408036e-16!GO:0050136;NADH dehydrogenase (quinone) activity;1.21616107028289e-15!GO:0003954;NADH dehydrogenase activity;1.21616107028289e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.21616107028289e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;1.56831829130323e-15!GO:0006605;protein targeting;2.13443455817182e-15!GO:0000502;proteasome complex (sensu Eukaryota);2.21896861051095e-15!GO:0044257;cellular protein catabolic process;2.36369752479951e-15!GO:0019941;modification-dependent protein catabolic process;2.47288548177299e-15!GO:0043632;modification-dependent macromolecule catabolic process;2.47288548177299e-15!GO:0006511;ubiquitin-dependent protein catabolic process;3.24650223769838e-15!GO:0043412;biopolymer modification;7.10585986868204e-15!GO:0006457;protein folding;7.50711637013585e-15!GO:0022618;protein-RNA complex assembly;3.02220787224121e-14!GO:0009056;catabolic process;3.24974917789457e-14!GO:0042775;organelle ATP synthesis coupled electron transport;4.08568940184682e-14!GO:0042773;ATP synthesis coupled electron transport;4.08568940184682e-14!GO:0030964;NADH dehydrogenase complex (quinone);6.43293625112988e-14!GO:0045271;respiratory chain complex I;6.43293625112988e-14!GO:0005747;mitochondrial respiratory chain complex I;6.43293625112988e-14!GO:0005768;endosome;9.09960505393259e-14!GO:0006464;protein modification process;1.06103208622119e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.14935754176831e-13!GO:0015934;large ribosomal subunit;1.16054107940181e-13!GO:0030163;protein catabolic process;1.16161237613065e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.09152854363604e-13!GO:0015935;small ribosomal subunit;2.87158338061373e-13!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;5.51301870782909e-13!GO:0042981;regulation of apoptosis;6.05468777119156e-13!GO:0022402;cell cycle process;6.2938920956845e-13!GO:0044451;nucleoplasm part;7.06304759533193e-13!GO:0016787;hydrolase activity;8.08061411104963e-13!GO:0042175;nuclear envelope-endoplasmic reticulum network;8.08061411104963e-13!GO:0005789;endoplasmic reticulum membrane;9.07205323919359e-13!GO:0030554;adenyl nucleotide binding;1.01671021862274e-12!GO:0005524;ATP binding;1.1175489153126e-12!GO:0032559;adenyl ribonucleotide binding;1.17949869241254e-12!GO:0043067;regulation of programmed cell death;1.21385506285509e-12!GO:0006974;response to DNA damage stimulus;1.36311709165413e-12!GO:0005635;nuclear envelope;1.61460694808237e-12!GO:0009055;electron carrier activity;2.23729813625811e-12!GO:0048193;Golgi vesicle transport;3.36430702129294e-12!GO:0008134;transcription factor binding;3.58971671020701e-12!GO:0051188;cofactor biosynthetic process;3.79175517565577e-12!GO:0043687;post-translational protein modification;5.37439002487466e-12!GO:0006163;purine nucleotide metabolic process;5.53527663070735e-12!GO:0006913;nucleocytoplasmic transport;5.99767563844674e-12!GO:0009259;ribonucleotide metabolic process;7.59464063206625e-12!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;8.21642640156375e-12!GO:0009150;purine ribonucleotide metabolic process;8.53147233115855e-12!GO:0051169;nuclear transport;1.24847679807266e-11!GO:0019829;cation-transporting ATPase activity;1.7354825666735e-11!GO:0006164;purine nucleotide biosynthetic process;2.17434548673465e-11!GO:0051082;unfolded protein binding;3.02245877574805e-11!GO:0016887;ATPase activity;3.03309393281072e-11!GO:0009152;purine ribonucleotide biosynthetic process;3.13006021207398e-11!GO:0015986;ATP synthesis coupled proton transport;3.25223741801821e-11!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.25223741801821e-11!GO:0042623;ATPase activity, coupled;3.82273992976431e-11!GO:0006950;response to stress;3.82900950594286e-11!GO:0000278;mitotic cell cycle;4.22731965023014e-11!GO:0015078;hydrogen ion transmembrane transporter activity;4.5515380497629e-11!GO:0009260;ribonucleotide biosynthetic process;6.63070995501075e-11!GO:0007249;I-kappaB kinase/NF-kappaB cascade;6.87705960382506e-11!GO:0008135;translation factor activity, nucleic acid binding;8.24267471176318e-11!GO:0005694;chromosome;1.41447141961878e-10!GO:0005761;mitochondrial ribosome;1.80722905593162e-10!GO:0000313;organellar ribosome;1.80722905593162e-10!GO:0006461;protein complex assembly;2.31055719460287e-10!GO:0009108;coenzyme biosynthetic process;3.11422931611034e-10!GO:0016491;oxidoreductase activity;3.26043146881877e-10!GO:0009205;purine ribonucleoside triphosphate metabolic process;4.06111259238135e-10!GO:0009144;purine nucleoside triphosphate metabolic process;4.06111259238135e-10!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.99495497740632e-10!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.99495497740632e-10!GO:0009199;ribonucleoside triphosphate metabolic process;4.99495497740632e-10!GO:0044453;nuclear membrane part;5.14403645321174e-10!GO:0005730;nucleolus;5.98659524100665e-10!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;6.33022328710023e-10!GO:0009142;nucleoside triphosphate biosynthetic process;6.46198812528291e-10!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.46198812528291e-10!GO:0031965;nuclear membrane;6.54589204640897e-10!GO:0051246;regulation of protein metabolic process;6.88961573508088e-10!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);7.31287244077971e-10!GO:0009141;nucleoside triphosphate metabolic process;8.08443115448136e-10!GO:0006754;ATP biosynthetic process;9.16001422631214e-10!GO:0006753;nucleoside phosphate metabolic process;9.16001422631214e-10!GO:0016604;nuclear body;1.06734335342212e-09!GO:0044427;chromosomal part;1.13298626743767e-09!GO:0009060;aerobic respiration;1.20022099826864e-09!GO:0046034;ATP metabolic process;1.20692223163698e-09!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.23529513437153e-09!GO:0016469;proton-transporting two-sector ATPase complex;1.28633431322238e-09!GO:0006281;DNA repair;1.33758810043148e-09!GO:0008639;small protein conjugating enzyme activity;1.53465455680072e-09!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.59291127645696e-09!GO:0008565;protein transporter activity;2.33803571116434e-09!GO:0006446;regulation of translational initiation;2.37503243724684e-09!GO:0005774;vacuolar membrane;2.58405078041254e-09!GO:0005770;late endosome;3.03573252171339e-09!GO:0043069;negative regulation of programmed cell death;3.18196283520959e-09!GO:0006793;phosphorus metabolic process;3.2156706118911e-09!GO:0006796;phosphate metabolic process;3.2156706118911e-09!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;3.28825816203e-09!GO:0006413;translational initiation;3.28825816203e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;3.28825816203e-09!GO:0000375;RNA splicing, via transesterification reactions;3.28825816203e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.28825816203e-09!GO:0004842;ubiquitin-protein ligase activity;3.49138911842829e-09!GO:0043066;negative regulation of apoptosis;3.77364797420507e-09!GO:0009719;response to endogenous stimulus;4.36848796361683e-09!GO:0005793;ER-Golgi intermediate compartment;4.37198473993742e-09!GO:0019787;small conjugating protein ligase activity;5.09574135991317e-09!GO:0003743;translation initiation factor activity;5.20916986992256e-09!GO:0017038;protein import;5.52039474061242e-09!GO:0015077;monovalent inorganic cation transmembrane transporter activity;6.15578595271979e-09!GO:0022403;cell cycle phase;6.96576052451673e-09!GO:0009117;nucleotide metabolic process;1.33633016423064e-08!GO:0007243;protein kinase cascade;1.42388950907246e-08!GO:0005765;lysosomal membrane;1.61172193069918e-08!GO:0044440;endosomal part;1.67841891421315e-08!GO:0010008;endosome membrane;1.67841891421315e-08!GO:0044437;vacuolar part;1.94426039856046e-08!GO:0045333;cellular respiration;2.13911833651527e-08!GO:0051301;cell division;2.43025923002346e-08!GO:0051276;chromosome organization and biogenesis;3.09345294707139e-08!GO:0000074;regulation of progression through cell cycle;3.18209173127625e-08!GO:0006916;anti-apoptosis;3.22252715789561e-08!GO:0005643;nuclear pore;3.59343324335081e-08!GO:0000087;M phase of mitotic cell cycle;3.93652385621467e-08!GO:0051726;regulation of cell cycle;3.97552732810506e-08!GO:0006752;group transfer coenzyme metabolic process;5.17990434149362e-08!GO:0006099;tricarboxylic acid cycle;5.47427320745591e-08!GO:0046356;acetyl-CoA catabolic process;5.47427320745591e-08!GO:0016607;nuclear speck;5.69358093450752e-08!GO:0007067;mitosis;5.75787726695876e-08!GO:0016310;phosphorylation;5.78454229420215e-08!GO:0016881;acid-amino acid ligase activity;5.7886635070125e-08!GO:0031252;leading edge;7.26235928397883e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;8.29772261749241e-08!GO:0006091;generation of precursor metabolites and energy;9.27243325758171e-08!GO:0007242;intracellular signaling cascade;9.60119750115834e-08!GO:0031982;vesicle;1.28995427496127e-07!GO:0006084;acetyl-CoA metabolic process;1.58520004074552e-07!GO:0051187;cofactor catabolic process;1.79332052833728e-07!GO:0005525;GTP binding;1.82213525913472e-07!GO:0005839;proteasome core complex (sensu Eukaryota);1.88772666663378e-07!GO:0046930;pore complex;2.138426756669e-07!GO:0008047;enzyme activator activity;2.3782045793735e-07!GO:0006325;establishment and/or maintenance of chromatin architecture;2.60580694795777e-07!GO:0044262;cellular carbohydrate metabolic process;2.95889757656034e-07!GO:0006888;ER to Golgi vesicle-mediated transport;4.11912071753428e-07!GO:0051170;nuclear import;4.15060872653053e-07!GO:0050657;nucleic acid transport;4.54294538850254e-07!GO:0051236;establishment of RNA localization;4.54294538850254e-07!GO:0050658;RNA transport;4.54294538850254e-07!GO:0044431;Golgi apparatus part;4.95174372866259e-07!GO:0065002;intracellular protein transport across a membrane;5.49702860370007e-07!GO:0006403;RNA localization;5.78900004222103e-07!GO:0006260;DNA replication;5.96440466316957e-07!GO:0031988;membrane-bound vesicle;6.11472151751126e-07!GO:0031410;cytoplasmic vesicle;6.13632426713631e-07!GO:0016044;membrane organization and biogenesis;6.29732612493707e-07!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;7.26214778662413e-07!GO:0009109;coenzyme catabolic process;7.47660509625816e-07!GO:0030120;vesicle coat;7.59184765450943e-07!GO:0030662;coated vesicle membrane;7.59184765450943e-07!GO:0006606;protein import into nucleus;8.28682717546178e-07!GO:0006323;DNA packaging;8.62080065522811e-07!GO:0007264;small GTPase mediated signal transduction;8.67066746890152e-07!GO:0007005;mitochondrion organization and biogenesis;9.3274351015152e-07!GO:0006818;hydrogen transport;1.02144535155972e-06!GO:0048523;negative regulation of cellular process;1.14403552206305e-06!GO:0003697;single-stranded DNA binding;1.15514558278833e-06!GO:0004298;threonine endopeptidase activity;1.21244705825321e-06!GO:0003712;transcription cofactor activity;1.38894428645484e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.45551012501783e-06!GO:0048475;coated membrane;1.4894583061318e-06!GO:0030117;membrane coat;1.4894583061318e-06!GO:0016023;cytoplasmic membrane-bound vesicle;1.68299139399491e-06!GO:0000279;M phase;1.68299139399491e-06!GO:0005798;Golgi-associated vesicle;1.77872449390277e-06!GO:0015992;proton transport;1.77872449390277e-06!GO:0065009;regulation of a molecular function;1.81633599310946e-06!GO:0008654;phospholipid biosynthetic process;1.87830066493967e-06!GO:0022890;inorganic cation transmembrane transporter activity;1.99668661313776e-06!GO:0019899;enzyme binding;2.90270566907014e-06!GO:0000785;chromatin;3.02515768933316e-06!GO:0004386;helicase activity;3.16752078662008e-06!GO:0032446;protein modification by small protein conjugation;3.22451212641285e-06!GO:0045259;proton-transporting ATP synthase complex;3.36805566544591e-06!GO:0016740;transferase activity;3.39167324985588e-06!GO:0016567;protein ubiquitination;3.39836924116872e-06!GO:0006399;tRNA metabolic process;3.4628091147079e-06!GO:0006333;chromatin assembly or disassembly;4.10569646415394e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;4.20321162146621e-06!GO:0015399;primary active transmembrane transporter activity;4.20321162146621e-06!GO:0001726;ruffle;4.2803162585459e-06!GO:0044255;cellular lipid metabolic process;4.3844042635211e-06!GO:0042254;ribosome biogenesis and assembly;4.39716345826753e-06!GO:0009165;nucleotide biosynthetic process;5.26662819286829e-06!GO:0032561;guanyl ribonucleotide binding;5.73706278573095e-06!GO:0019001;guanyl nucleotide binding;5.73706278573095e-06!GO:0006417;regulation of translation;6.14232396616311e-06!GO:0007033;vacuole organization and biogenesis;7.08974755604809e-06!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;7.65194051452419e-06!GO:0004812;aminoacyl-tRNA ligase activity;7.65194051452419e-06!GO:0016875;ligase activity, forming carbon-oxygen bonds;7.65194051452419e-06!GO:0007040;lysosome organization and biogenesis;7.93472261145238e-06!GO:0043566;structure-specific DNA binding;8.6180891804496e-06!GO:0005096;GTPase activator activity;9.30408962730983e-06!GO:0051028;mRNA transport;9.53031965368003e-06!GO:0043065;positive regulation of apoptosis;1.06280732291965e-05!GO:0043038;amino acid activation;1.08500057157002e-05!GO:0006418;tRNA aminoacylation for protein translation;1.08500057157002e-05!GO:0043039;tRNA aminoacylation;1.08500057157002e-05!GO:0048519;negative regulation of biological process;1.09248586027022e-05!GO:0030532;small nuclear ribonucleoprotein complex;1.11998802930891e-05!GO:0031902;late endosome membrane;1.30261150051201e-05!GO:0003676;nucleic acid binding;1.3080383138733e-05!GO:0005769;early endosome;1.47279285506969e-05!GO:0019752;carboxylic acid metabolic process;1.49130839468e-05!GO:0003924;GTPase activity;1.5002498151708e-05!GO:0000151;ubiquitin ligase complex;1.50708228445023e-05!GO:0043068;positive regulation of programmed cell death;1.63154019684091e-05!GO:0008026;ATP-dependent helicase activity;1.64799783745495e-05!GO:0043492;ATPase activity, coupled to movement of substances;1.76437820514268e-05!GO:0006082;organic acid metabolic process;1.83993589079818e-05!GO:0006643;membrane lipid metabolic process;1.90508944647679e-05!GO:0065004;protein-DNA complex assembly;2.05678864146828e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;2.15775370266322e-05!GO:0009615;response to virus;2.27464927281578e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.04032863247231e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;3.18105693005861e-05!GO:0006613;cotranslational protein targeting to membrane;3.77038540269942e-05!GO:0008610;lipid biosynthetic process;4.33156618185752e-05!GO:0000139;Golgi membrane;4.79489139460727e-05!GO:0032940;secretion by cell;4.80617269390979e-05!GO:0045454;cell redox homeostasis;5.04026911686734e-05!GO:0031326;regulation of cellular biosynthetic process;6.98582343287696e-05!GO:0043623;cellular protein complex assembly;7.01271933162965e-05!GO:0030695;GTPase regulator activity;7.02974733678554e-05!GO:0016568;chromatin modification;7.33585205222621e-05!GO:0015630;microtubule cytoskeleton;7.71504557333638e-05!GO:0005975;carbohydrate metabolic process;8.01904068387992e-05!GO:0046519;sphingoid metabolic process;8.16980090519891e-05!GO:0006629;lipid metabolic process;8.39989888120081e-05!GO:0006672;ceramide metabolic process;9.11760080907514e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;9.3716929320342e-05!GO:0005741;mitochondrial outer membrane;9.91695361768385e-05!GO:0000245;spliceosome assembly;0.000105868590272405!GO:0009889;regulation of biosynthetic process;0.000106573818892107!GO:0019867;outer membrane;0.00011132520279901!GO:0006650;glycerophospholipid metabolic process;0.000112361783294428!GO:0005813;centrosome;0.000114476508648676!GO:0016197;endosome transport;0.000129149796550814!GO:0016853;isomerase activity;0.00013016796141062!GO:0031968;organelle outer membrane;0.00013016796141062!GO:0005885;Arp2/3 protein complex;0.000133525097377758!GO:0009967;positive regulation of signal transduction;0.000154434853748421!GO:0006334;nucleosome assembly;0.000176821371930178!GO:0006897;endocytosis;0.000185664280212484!GO:0010324;membrane invagination;0.000185664280212484!GO:0016779;nucleotidyltransferase activity;0.000187055261491851!GO:0048522;positive regulation of cellular process;0.00019707241791517!GO:0045786;negative regulation of progression through cell cycle;0.000202243443747754!GO:0030036;actin cytoskeleton organization and biogenesis;0.000205816706310436!GO:0005788;endoplasmic reticulum lumen;0.000206212520143915!GO:0050790;regulation of catalytic activity;0.000209163117664616!GO:0006612;protein targeting to membrane;0.000209217540428294!GO:0033116;ER-Golgi intermediate compartment membrane;0.000219410811262422!GO:0006917;induction of apoptosis;0.000222848583965582!GO:0007034;vacuolar transport;0.000223260101639523!GO:0015980;energy derivation by oxidation of organic compounds;0.000223982283499876!GO:0045045;secretory pathway;0.000233336645973754!GO:0051168;nuclear export;0.000240047067918415!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000241986822747734!GO:0031497;chromatin assembly;0.00025308794639149!GO:0005762;mitochondrial large ribosomal subunit;0.000262956113855681!GO:0000315;organellar large ribosomal subunit;0.000262956113855681!GO:0046483;heterocycle metabolic process;0.000288509370876776!GO:0012502;induction of programmed cell death;0.000328653849655144!GO:0005815;microtubule organizing center;0.000354520173728177!GO:0006644;phospholipid metabolic process;0.000358489647116028!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000367044885569977!GO:0007265;Ras protein signal transduction;0.000372505770939886!GO:0006364;rRNA processing;0.000388301255976773!GO:0051329;interphase of mitotic cell cycle;0.000419394691926164!GO:0016072;rRNA metabolic process;0.00042978391156465!GO:0051325;interphase;0.000450591216681654!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000555401631342519!GO:0005083;small GTPase regulator activity;0.000662825218703192!GO:0006401;RNA catabolic process;0.000677461680674909!GO:0046474;glycerophospholipid biosynthetic process;0.0006979178133863!GO:0016070;RNA metabolic process;0.000709514859662353!GO:0046467;membrane lipid biosynthetic process;0.000740760984401516!GO:0003724;RNA helicase activity;0.000776063661540888!GO:0003713;transcription coactivator activity;0.000826459909879612!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000831823788099787!GO:0005819;spindle;0.000831823788099787!GO:0030027;lamellipodium;0.000880092740069851!GO:0030133;transport vesicle;0.000885058801135002!GO:0016126;sterol biosynthetic process;0.0010150924722032!GO:0050662;coenzyme binding;0.00105597974013847!GO:0030867;rough endoplasmic reticulum membrane;0.00105702980753464!GO:0048518;positive regulation of biological process;0.00113137965712279!GO:0043021;ribonucleoprotein binding;0.00113137965712279!GO:0030029;actin filament-based process;0.0011754025917257!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.00120461512924911!GO:0048487;beta-tubulin binding;0.00120802591512881!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00122422037704213!GO:0008632;apoptotic program;0.00126148745770213!GO:0007041;lysosomal transport;0.00127022372628805!GO:0051336;regulation of hydrolase activity;0.00132296927701665!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00133278692956697!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00133278692956697!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00133278692956697!GO:0030658;transport vesicle membrane;0.00143868482638911!GO:0048471;perinuclear region of cytoplasm;0.00143868482638911!GO:0002376;immune system process;0.00143868482638911!GO:0005099;Ras GTPase activator activity;0.00146300808904038!GO:0030176;integral to endoplasmic reticulum membrane;0.00152441380356663!GO:0006118;electron transport;0.00153995359681456!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.0015684700205436!GO:0006261;DNA-dependent DNA replication;0.00158584784969623!GO:0007006;mitochondrial membrane organization and biogenesis;0.00161115700354338!GO:0030984;kininogen binding;0.00176247724410099!GO:0004213;cathepsin B activity;0.00176247724410099!GO:0043087;regulation of GTPase activity;0.0017867587931247!GO:0030384;phosphoinositide metabolic process;0.00189689778470026!GO:0006749;glutathione metabolic process;0.00190047642152906!GO:0042802;identical protein binding;0.00199352916147839!GO:0019318;hexose metabolic process;0.0021312711249693!GO:0030149;sphingolipid catabolic process;0.00216387181113687!GO:0006607;NLS-bearing substrate import into nucleus;0.00219092238525729!GO:0003729;mRNA binding;0.00219616893374457!GO:0051789;response to protein stimulus;0.00223610830807835!GO:0006986;response to unfolded protein;0.00223610830807835!GO:0019377;glycolipid catabolic process;0.00229670178502359!GO:0006767;water-soluble vitamin metabolic process;0.00236709838376255!GO:0042613;MHC class II protein complex;0.00238556084307023!GO:0050794;regulation of cellular process;0.00242069960962695!GO:0006366;transcription from RNA polymerase II promoter;0.0025927433232536!GO:0006839;mitochondrial transport;0.0025927433232536!GO:0005996;monosaccharide metabolic process;0.00272449201928438!GO:0000775;chromosome, pericentric region;0.00276276210165836!GO:0051427;hormone receptor binding;0.00278676508153904!GO:0005637;nuclear inner membrane;0.0028026303201259!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00287944021854048!GO:0006733;oxidoreduction coenzyme metabolic process;0.00292324948633872!GO:0030660;Golgi-associated vesicle membrane;0.00292976855551839!GO:0005791;rough endoplasmic reticulum;0.00296474966160123!GO:0005048;signal sequence binding;0.00297303685433339!GO:0008234;cysteine-type peptidase activity;0.00302838362784124!GO:0003714;transcription corepressor activity;0.00315020079333329!GO:0051920;peroxiredoxin activity;0.00319069476534688!GO:0004229;gelatinase B activity;0.00328397234490668!GO:0006302;double-strand break repair;0.00335758923665433!GO:0015631;tubulin binding;0.0034436492475907!GO:0006891;intra-Golgi vesicle-mediated transport;0.00349996217981536!GO:0031072;heat shock protein binding;0.00360440108730433!GO:0006310;DNA recombination;0.00360997990510245!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0036189590114576!GO:0000287;magnesium ion binding;0.00366994043357835!GO:0016564;transcription repressor activity;0.00374146283771096!GO:0000082;G1/S transition of mitotic cell cycle;0.00374146283771096!GO:0006807;nitrogen compound metabolic process;0.00385612518856825!GO:0006979;response to oxidative stress;0.00385852831829072!GO:0007051;spindle organization and biogenesis;0.00394883858880757!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.00412896727486802!GO:0051252;regulation of RNA metabolic process;0.00421979541887419!GO:0019904;protein domain specific binding;0.00431521199132004!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00437345071698448!GO:0046489;phosphoinositide biosynthetic process;0.00438408504226744!GO:0004177;aminopeptidase activity;0.00443140503343162!GO:0005657;replication fork;0.00451074513297117!GO:0043681;protein import into mitochondrion;0.00470513384201339!GO:0030663;COPI coated vesicle membrane;0.00471391876678456!GO:0030126;COPI vesicle coat;0.00471391876678456!GO:0015036;disulfide oxidoreductase activity;0.00475157448043988!GO:0035257;nuclear hormone receptor binding;0.00481245030369014!GO:0000075;cell cycle checkpoint;0.00486105057827127!GO:0000314;organellar small ribosomal subunit;0.00486481881735705!GO:0005763;mitochondrial small ribosomal subunit;0.00486481881735705!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00499751271053182!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00499751271053182!GO:0030118;clathrin coat;0.00509417532376266!GO:0008139;nuclear localization sequence binding;0.00509417532376266!GO:0000059;protein import into nucleus, docking;0.00511109816732319!GO:0048468;cell development;0.00519525029279659!GO:0006402;mRNA catabolic process;0.005328346936505!GO:0006066;alcohol metabolic process;0.00533286873176943!GO:0006695;cholesterol biosynthetic process;0.00543716657607874!GO:0017166;vinculin binding;0.00545663124312684!GO:0003690;double-stranded DNA binding;0.00547456325826049!GO:0043488;regulation of mRNA stability;0.00579759420888819!GO:0043487;regulation of RNA stability;0.00579759420888819!GO:0007010;cytoskeleton organization and biogenesis;0.00583032641861445!GO:0006778;porphyrin metabolic process;0.00583032641861445!GO:0033013;tetrapyrrole metabolic process;0.00583032641861445!GO:0000776;kinetochore;0.00591735823232208!GO:0006516;glycoprotein catabolic process;0.00596308941771998!GO:0046822;regulation of nucleocytoplasmic transport;0.00596308941771998!GO:0005905;coated pit;0.00615628113297368!GO:0006007;glucose catabolic process;0.0063727593565031!GO:0051287;NAD binding;0.00639929037354982!GO:0008637;apoptotic mitochondrial changes;0.00663388893392226!GO:0046479;glycosphingolipid catabolic process;0.00666646638487017!GO:0031901;early endosome membrane;0.00678798902045485!GO:0006414;translational elongation;0.00681482807219211!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00685060386487749!GO:0015002;heme-copper terminal oxidase activity;0.00685060386487749!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00685060386487749!GO:0004129;cytochrome-c oxidase activity;0.00685060386487749!GO:0006955;immune response;0.00689100754043997!GO:0004674;protein serine/threonine kinase activity;0.00689100754043997!GO:0008186;RNA-dependent ATPase activity;0.00763931758666396!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00767576996243177!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00771298112796633!GO:0032318;regulation of Ras GTPase activity;0.00804853556456132!GO:0006611;protein export from nucleus;0.00807898571583027!GO:0022415;viral reproductive process;0.0081690993282101!GO:0030137;COPI-coated vesicle;0.0081690993282101!GO:0000786;nucleosome;0.00824545635659266!GO:0016859;cis-trans isomerase activity;0.00826819564428856!GO:0006509;membrane protein ectodomain proteolysis;0.00828792762849268!GO:0033619;membrane protein proteolysis;0.00828792762849268!GO:0004197;cysteine-type endopeptidase activity;0.00848274410194664!GO:0007050;cell cycle arrest;0.00860906501156839!GO:0048500;signal recognition particle;0.00874757057257179!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00887358532665547!GO:0008629;induction of apoptosis by intracellular signals;0.00893921468126965!GO:0030134;ER to Golgi transport vesicle;0.00960789746656089!GO:0016788;hydrolase activity, acting on ester bonds;0.00963027858913243!GO:0004185;serine carboxypeptidase activity;0.00971390890641059!GO:0006635;fatty acid beta-oxidation;0.00983309915944071!GO:0051540;metal cluster binding;0.0100238855789863!GO:0051536;iron-sulfur cluster binding;0.0100238855789863!GO:0016860;intramolecular oxidoreductase activity;0.0100734961185997!GO:0006626;protein targeting to mitochondrion;0.0101482752152191!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0109724641919911!GO:0042168;heme metabolic process;0.0112130828977666!GO:0009607;response to biotic stimulus;0.0112992329614673!GO:0031324;negative regulation of cellular metabolic process;0.0116395850122472!GO:0006740;NADPH regeneration;0.0116438653942786!GO:0006098;pentose-phosphate shunt;0.0116438653942786!GO:0030132;clathrin coat of coated pit;0.0118171828606804!GO:0045309;protein phosphorylated amino acid binding;0.0119211136136194!GO:0016408;C-acyltransferase activity;0.0119955281076337!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0120197861381209!GO:0030127;COPII vesicle coat;0.0120802441474048!GO:0012507;ER to Golgi transport vesicle membrane;0.0120802441474048!GO:0044438;microbody part;0.0120802441474048!GO:0044439;peroxisomal part;0.0120802441474048!GO:0030119;AP-type membrane coat adaptor complex;0.0124918826023518!GO:0005684;U2-dependent spliceosome;0.0125884435758402!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0128641380522334!GO:0046466;membrane lipid catabolic process;0.0128641380522334!GO:0044275;cellular carbohydrate catabolic process;0.0128865029798192!GO:0006006;glucose metabolic process;0.0132615215378137!GO:0051539;4 iron, 4 sulfur cluster binding;0.0136650731837499!GO:0009112;nucleobase metabolic process;0.0142025719167558!GO:0030503;regulation of cell redox homeostasis;0.0143004799353853!GO:0016791;phosphoric monoester hydrolase activity;0.0145385667313351!GO:0009966;regulation of signal transduction;0.0148068136952251!GO:0019079;viral genome replication;0.014821976602637!GO:0030140;trans-Golgi network transport vesicle;0.0149906006863921!GO:0009116;nucleoside metabolic process;0.0149906006863921!GO:0006383;transcription from RNA polymerase III promoter;0.0150382377646167!GO:0007088;regulation of mitosis;0.0150593624583324!GO:0009308;amine metabolic process;0.0151779086670866!GO:0000096;sulfur amino acid metabolic process;0.0155065358488328!GO:0006914;autophagy;0.0155065358488328!GO:0001784;phosphotyrosine binding;0.0155235132676622!GO:0016563;transcription activator activity;0.0157427202536449!GO:0016125;sterol metabolic process;0.0157495646152818!GO:0006458;'de novo' protein folding;0.0159240562473882!GO:0051084;'de novo' posttranslational protein folding;0.0159240562473882!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.016144632008328!GO:0045047;protein targeting to ER;0.016144632008328!GO:0048037;cofactor binding;0.0162790160130889!GO:0046983;protein dimerization activity;0.0164986377090515!GO:0006769;nicotinamide metabolic process;0.0166196220921623!GO:0005667;transcription factor complex;0.0171785413930132!GO:0019362;pyridine nucleotide metabolic process;0.0171972843492932!GO:0003725;double-stranded RNA binding;0.01728322657478!GO:0051098;regulation of binding;0.017294680858154!GO:0006595;polyamine metabolic process;0.0173012900641619!GO:0004004;ATP-dependent RNA helicase activity;0.0175661946663867!GO:0002444;myeloid leukocyte mediated immunity;0.01772961779191!GO:0022406;membrane docking;0.0179919856475873!GO:0048278;vesicle docking;0.0179919856475873!GO:0006665;sphingolipid metabolic process;0.0180240366735823!GO:0004518;nuclease activity;0.0181021136194494!GO:0032787;monocarboxylic acid metabolic process;0.0181392947783584!GO:0031903;microbody membrane;0.0182457332208902!GO:0005778;peroxisomal membrane;0.0182457332208902!GO:0030131;clathrin adaptor complex;0.0182883163460854!GO:0004192;cathepsin D activity;0.0189616359852971!GO:0030145;manganese ion binding;0.019304906770183!GO:0051052;regulation of DNA metabolic process;0.019431578485598!GO:0005869;dynactin complex;0.0195895323132556!GO:0007162;negative regulation of cell adhesion;0.0198930877343618!GO:0000910;cytokinesis;0.0202052038412504!GO:0006689;ganglioside catabolic process;0.0204057264867572!GO:0006631;fatty acid metabolic process;0.0207087886858024!GO:0004576;oligosaccharyl transferase activity;0.0208556315262122!GO:0051881;regulation of mitochondrial membrane potential;0.0208595043447697!GO:0033033;negative regulation of myeloid cell apoptosis;0.0208653994379291!GO:0001803;regulation of type III hypersensitivity;0.0208653994379291!GO:0032733;positive regulation of interleukin-10 production;0.0208653994379291!GO:0033025;regulation of mast cell apoptosis;0.0208653994379291!GO:0001805;positive regulation of type III hypersensitivity;0.0208653994379291!GO:0033023;mast cell homeostasis;0.0208653994379291!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0208653994379291!GO:0033032;regulation of myeloid cell apoptosis;0.0208653994379291!GO:0001802;type III hypersensitivity;0.0208653994379291!GO:0033028;myeloid cell apoptosis;0.0208653994379291!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0208653994379291!GO:0033026;negative regulation of mast cell apoptosis;0.0208653994379291!GO:0033024;mast cell apoptosis;0.0208653994379291!GO:0035035;histone acetyltransferase binding;0.0210129064768829!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0213528710565192!GO:0008094;DNA-dependent ATPase activity;0.0218904680791545!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0218904680791545!GO:0000209;protein polyubiquitination;0.0224006571747008!GO:0030125;clathrin vesicle coat;0.0224006571747008!GO:0030665;clathrin coated vesicle membrane;0.0224006571747008!GO:0003899;DNA-directed RNA polymerase activity;0.0224778624659707!GO:0042158;lipoprotein biosynthetic process;0.0224778624659707!GO:0051219;phosphoprotein binding;0.0224778624659707!GO:0006497;protein amino acid lipidation;0.0227260288492721!GO:0032428;beta-N-acetylgalactosaminidase activity;0.0228305231474457!GO:0030290;sphingolipid activator protein activity;0.0228305231474457!GO:0051452;cellular pH reduction;0.0236537708719324!GO:0051453;regulation of cellular pH;0.0236537708719324!GO:0045851;pH reduction;0.0236537708719324!GO:0006779;porphyrin biosynthetic process;0.0238731663746886!GO:0033014;tetrapyrrole biosynthetic process;0.0238731663746886!GO:0008312;7S RNA binding;0.0241666819655358!GO:0000339;RNA cap binding;0.0242687303727382!GO:0004563;beta-N-acetylhexosaminidase activity;0.0243374977797524!GO:0009892;negative regulation of metabolic process;0.0246478588579995!GO:0005777;peroxisome;0.0247260889542942!GO:0042579;microbody;0.0247260889542942!GO:0006520;amino acid metabolic process;0.0247587051949753!GO:0006904;vesicle docking during exocytosis;0.0251961688889612!GO:0030041;actin filament polymerization;0.0255034571116822!GO:0043130;ubiquitin binding;0.0255243687660478!GO:0032182;small conjugating protein binding;0.0255243687660478!GO:0016363;nuclear matrix;0.0260046264299444!GO:0004722;protein serine/threonine phosphatase activity;0.0261941950600782!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0262320392665158!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0263464689183378!GO:0006954;inflammatory response;0.0266260956281746!GO:0016584;nucleosome positioning;0.0266279268442721!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0267334575299347!GO:0031625;ubiquitin protein ligase binding;0.0268714129940118!GO:0006739;NADP metabolic process;0.0269881071779224!GO:0008250;oligosaccharyl transferase complex;0.0270020140495003!GO:0019843;rRNA binding;0.0270020140495003!GO:0050789;regulation of biological process;0.0272584106241463!GO:0006405;RNA export from nucleus;0.0276254699588203!GO:0006984;ER-nuclear signaling pathway;0.0277132479645112!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0280769996646794!GO:0050749;apolipoprotein E receptor binding;0.0280961290547693!GO:0048002;antigen processing and presentation of peptide antigen;0.0280961290547693!GO:0000303;response to superoxide;0.0283284808575071!GO:0009124;nucleoside monophosphate biosynthetic process;0.0284680044915518!GO:0009123;nucleoside monophosphate metabolic process;0.0284680044915518!GO:0031301;integral to organelle membrane;0.028550324481706!GO:0007059;chromosome segregation;0.028629573325834!GO:0008017;microtubule binding;0.0291735712061334!GO:0050811;GABA receptor binding;0.0291949264927415!GO:0051101;regulation of DNA binding;0.0293700993016712!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0299284200464804!GO:0046456;icosanoid biosynthetic process;0.0302937708841782!GO:0008287;protein serine/threonine phosphatase complex;0.0303461458477167!GO:0042987;amyloid precursor protein catabolic process;0.0303975353986247!GO:0018193;peptidyl-amino acid modification;0.0305988209239622!GO:0000118;histone deacetylase complex;0.0306157905171184!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0306887974139222!GO:0043022;ribosome binding;0.0306887974139222!GO:0006790;sulfur metabolic process;0.0306887974139222!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0309353842181813!GO:0006213;pyrimidine nucleoside metabolic process;0.0309353842181813!GO:0005758;mitochondrial intermembrane space;0.0315101289117036!GO:0030880;RNA polymerase complex;0.0317383055671831!GO:0035258;steroid hormone receptor binding;0.0318221443131305!GO:0015248;sterol transporter activity;0.0318673864953238!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0318707496069962!GO:0007093;mitotic cell cycle checkpoint;0.0319577878642536!GO:0016798;hydrolase activity, acting on glycosyl bonds;0.0328061790079115!GO:0019058;viral infectious cycle;0.0332158903677357!GO:0046870;cadmium ion binding;0.0332271911362029!GO:0006633;fatty acid biosynthetic process;0.0332631865980286!GO:0030508;thiol-disulfide exchange intermediate activity;0.033455084790646!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0335527119662224!GO:0005784;translocon complex;0.0337282337253945!GO:0005832;chaperonin-containing T-complex;0.0337282337253945!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0339667806366708!GO:0031124;mRNA 3'-end processing;0.0342585323013021!GO:0000305;response to oxygen radical;0.0345274186033227!GO:0001836;release of cytochrome c from mitochondria;0.0347504671311923!GO:0006465;signal peptide processing;0.034967487537592!GO:0004448;isocitrate dehydrogenase activity;0.034967487537592!GO:0051338;regulation of transferase activity;0.0350500139751947!GO:0016311;dephosphorylation;0.0370407836885752!GO:0005484;SNAP receptor activity;0.0384087939588776!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0387059021081749!GO:0010257;NADH dehydrogenase complex assembly;0.0387059021081749!GO:0033108;mitochondrial respiratory chain complex assembly;0.0387059021081749!GO:0006518;peptide metabolic process;0.0389007327918387!GO:0046365;monosaccharide catabolic process;0.0391710927186538!GO:0032508;DNA duplex unwinding;0.0395136027306513!GO:0032392;DNA geometric change;0.0395136027306513!GO:0008383;manganese superoxide dismutase activity;0.0395136027306513!GO:0001315;age-dependent response to reactive oxygen species;0.0395136027306513!GO:0051223;regulation of protein transport;0.0395796574376875!GO:0051348;negative regulation of transferase activity;0.0399130585635429!GO:0043284;biopolymer biosynthetic process;0.039986433620026!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.04018318582417!GO:0003678;DNA helicase activity;0.0402913414863802!GO:0016301;kinase activity;0.0402913414863802!GO:0019882;antigen processing and presentation;0.0407947664981639!GO:0006622;protein targeting to lysosome;0.0411713177963466!GO:0051090;regulation of transcription factor activity;0.0419363359708241!GO:0051085;chaperone cofactor-dependent protein folding;0.0420057383524188!GO:0016615;malate dehydrogenase activity;0.0420290732847782!GO:0001573;ganglioside metabolic process;0.0420565245065901!GO:0006268;DNA unwinding during replication;0.0424824993247318!GO:0008538;proteasome activator activity;0.0425837078212226!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0430697746117071!GO:0032760;positive regulation of tumor necrosis factor production;0.0434363717220777!GO:0003684;damaged DNA binding;0.04378147644294!GO:0006783;heme biosynthetic process;0.0440255009481065!GO:0000152;nuclear ubiquitin ligase complex;0.0440255009481065!GO:0004235;matrilysin activity;0.0446903433869058!GO:0033673;negative regulation of kinase activity;0.0448140292712285!GO:0006469;negative regulation of protein kinase activity;0.0448140292712285!GO:0005876;spindle microtubule;0.0448512888369639!GO:0043299;leukocyte degranulation;0.045521093786564!GO:0032763;regulation of mast cell cytokine production;0.0461413288310565!GO:0032762;mast cell cytokine production;0.0461413288310565!GO:0030099;myeloid cell differentiation;0.0461413288310565!GO:0043281;regulation of caspase activity;0.0461413288310565!GO:0004218;cathepsin S activity;0.0462614100935212!GO:0046394;carboxylic acid biosynthetic process;0.04632491152842!GO:0016053;organic acid biosynthetic process;0.04632491152842!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0466948963000018!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0466948963000018!GO:0009126;purine nucleoside monophosphate metabolic process;0.0466948963000018!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0466948963000018!GO:0019747;regulation of isoprenoid metabolic process;0.0469586616464592!GO:0045576;mast cell activation;0.0472612127456314!GO:0009161;ribonucleoside monophosphate metabolic process;0.0478046733111925!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0478046733111925!GO:0046164;alcohol catabolic process;0.0479161410737363!GO:0006352;transcription initiation;0.0479161410737363!GO:0008415;acyltransferase activity;0.0481184939649089
|sample_id=11389
|sample_id=11389
|sample_note=
|sample_note=
Line 75: Line 105:
|sample_tissue=blood
|sample_tissue=blood
|top_motifs=SREBF1,2:2.32896586372;TLX2:2.24975398492;EN1,2:1.62732266683;FOXP3:1.44000490437;MTF1:1.34355132117;SPI1:1.19766222683;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.19107443868;SPIB:1.08270896144;NANOG{mouse}:0.957096493079;TFCP2:0.934541458675;ESRRA:0.930897951517;ESR1:0.89204775161;ELF1,2,4:0.877869873672;TFAP4:0.854038675864;ETS1,2:0.831048446804;NFE2L2:0.810240309268;PPARG:0.78055113654;IRF1,2:0.779246205385;NFIL3:0.776147640967;IRF7:0.753206573213;MYOD1:0.728833219847;RXRA_VDR{dimer}:0.725278438477;DMAP1_NCOR{1,2}_SMARC:0.666675590083;IKZF2:0.663020551629;GLI1..3:0.616323788597;NR6A1:0.593891466047;PAX8:0.56718725746;HLF:0.548331619794;EBF1:0.495332230792;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.488582888671;AR:0.45816968256;SPZ1:0.444447743594;PAX2:0.405902966855;HNF4A_NR2F1,2:0.397657993885;EP300:0.375988160098;NKX3-2:0.35362230892;FOXD3:0.347255077039;HES1:0.331231773729;HMX1:0.284574395277;NKX2-2,8:0.274753058889;XCPE1{core}:0.255329056865;RUNX1..3:0.254591961767;STAT2,4,6:0.23795769523;VSX1,2:0.232111836225;FOSL2:0.216458905201;ZBTB16:0.210486315658;OCT4_SOX2{dimer}:0.209050908788;PAX6:0.185736668283;PRDM1:0.139724444548;PAX5:0.132992672019;TGIF1:0.0955175544574;TAL1_TCF{3,4,12}:0.0856257642476;TBP:0.0812688537738;NR1H4:0.077297040487;MYB:0.058923223821;SP1:0.0580124287011;POU1F1:0.0259835802251;POU5F1:0.0231859810053;NFY{A,B,C}:0.00746710071004;ARID5B:-0.0023146101077;E2F1..5:-0.00728032973677;NFE2:-0.0187057450076;KLF4:-0.0271381381949;GZF1:-0.0486595894582;ZNF143:-0.0707976136834;NFKB1_REL_RELA:-0.0719027457969;FOX{F1,F2,J1}:-0.101419574118;MYFfamily:-0.114787243965;RFX2..5_RFXANK_RFXAP:-0.120267436637;NKX2-3_NKX2-5:-0.125125693584;CEBPA,B_DDIT3:-0.127659437975;TOPORS:-0.137290588423;FOXO1,3,4:-0.140188620708;STAT1,3:-0.168197820135;GATA4:-0.173089137016;ZFP161:-0.179781828989;NRF1:-0.191255446378;FOXN1:-0.196684254764;PRRX1,2:-0.200971433461;NHLH1,2:-0.211002323666;YY1:-0.211066661798;BACH2:-0.223837236982;HBP1_HMGB_SSRP1_UBTF:-0.255112991635;SMAD1..7,9:-0.256788642539;GATA6:-0.258329981246;FOS_FOS{B,L1}_JUN{B,D}:-0.261519788072;PAX1,9:-0.263042366467;FOXP1:-0.271972122522;EGR1..3:-0.279160526195;ATF4:-0.286649392907;REST:-0.299349619405;ELK1,4_GABP{A,B1}:-0.305430806249;ALX4:-0.308911336252;NFE2L1:-0.327239617874;STAT5{A,B}:-0.327301242062;ZNF148:-0.33178606382;POU3F1..4:-0.357791252728;TFDP1:-0.383027185616;CDX1,2,4:-0.385503081593;PAX3,7:-0.399641542927;CREB1:-0.399985524232;UFEwm:-0.40550418204;HAND1,2:-0.414100468902;FOXA2:-0.416665507374;HIC1:-0.436570460933;HNF1A:-0.439648986418;NR5A1,2:-0.45930589454;NFIX:-0.475547523372;ZEB1:-0.481256214249;CRX:-0.484197303621;HSF1,2:-0.504998933324;NKX6-1,2:-0.509878532802;TFAP2{A,C}:-0.519380865405;SOX{8,9,10}:-0.525412913703;IKZF1:-0.527370730926;LMO2:-0.536432233342;LHX3,4:-0.557947902879;bHLH_family:-0.573845821488;CUX2:-0.580260272979;NR3C1:-0.58262785485;ATF5_CREB3:-0.583255804318;ALX1:-0.598253919436;PDX1:-0.607503877599;TFAP2B:-0.608054307497;ZNF423:-0.629761377599;PITX1..3:-0.634308522971;MAFB:-0.641910823115;HMGA1,2:-0.642827863105;ATF2:-0.666538388148;ZBTB6:-0.673240983056;RXR{A,B,G}:-0.674037147586;HIF1A:-0.68388541708;RORA:-0.694636402707;GFI1:-0.69866523462;HOX{A5,B5}:-0.712626791125;ONECUT1,2:-0.712648074261;TEF:-0.713450846256;RREB1:-0.732194376309;GTF2I:-0.744102580637;MAZ:-0.749411161241;MEF2{A,B,C,D}:-0.751306654592;TLX1..3_NFIC{dimer}:-0.752414825402;PAX4:-0.770729945613;FOX{D1,D2}:-0.773976951102;GFI1B:-0.774501532538;JUN:-0.811568898822;SNAI1..3:-0.822024000682;MYBL2:-0.840646771801;SRF:-0.842542607999;MTE{core}:-0.846152646773;GCM1,2:-0.854784653524;HOX{A6,A7,B6,B7}:-0.864916528124;GTF2A1,2:-0.876681570719;ADNP_IRX_SIX_ZHX:-0.877037778688;NANOG:-0.912214539538;T:-0.942707277536;ZNF238:-0.95254476181;NFATC1..3:-0.960887920453;BREu{core}:-0.964559406402;POU6F1:-1.01783915969;PATZ1:-1.02013930375;MED-1{core}:-1.03622206462;TP53:-1.03961911913;SOX2:-1.0462857249;POU2F1..3:-1.05400518657;TEAD1:-1.05481290707;ATF6:-1.08695736647;MZF1:-1.10294922165;SOX17:-1.10511314641;HOXA9_MEIS1:-1.11305368801;HOX{A4,D4}:-1.12128464694;DBP:-1.13083289517;NKX3-1:-1.13833841832;XBP1:-1.14056745484;ZIC1..3:-1.14183811248;FOX{I1,J2}:-1.1672214664;TBX4,5:-1.25926721528;RFX1:-1.31541120004;CDC5L:-1.33081197807;FOXQ1:-1.33811558424;SOX5:-1.36719937784;BPTF:-1.37545800601;EVI1:-1.44586229744;AHR_ARNT_ARNT2:-1.4620458321;AIRE:-1.51771685777;FOXM1:-1.56410471173;PBX1:-1.65129026153;LEF1_TCF7_TCF7L1,2:-1.74431749823;ZNF384:-1.91891566852;RBPJ:-1.96324874322;FOXL1:-2.14609333576;NKX2-1,4:-2.68811297328
|top_motifs=SREBF1,2:2.32896586372;TLX2:2.24975398492;EN1,2:1.62732266683;FOXP3:1.44000490437;MTF1:1.34355132117;SPI1:1.19766222683;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.19107443868;SPIB:1.08270896144;NANOG{mouse}:0.957096493079;TFCP2:0.934541458675;ESRRA:0.930897951517;ESR1:0.89204775161;ELF1,2,4:0.877869873672;TFAP4:0.854038675864;ETS1,2:0.831048446804;NFE2L2:0.810240309268;PPARG:0.78055113654;IRF1,2:0.779246205385;NFIL3:0.776147640967;IRF7:0.753206573213;MYOD1:0.728833219847;RXRA_VDR{dimer}:0.725278438477;DMAP1_NCOR{1,2}_SMARC:0.666675590083;IKZF2:0.663020551629;GLI1..3:0.616323788597;NR6A1:0.593891466047;PAX8:0.56718725746;HLF:0.548331619794;EBF1:0.495332230792;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.488582888671;AR:0.45816968256;SPZ1:0.444447743594;PAX2:0.405902966855;HNF4A_NR2F1,2:0.397657993885;EP300:0.375988160098;NKX3-2:0.35362230892;FOXD3:0.347255077039;HES1:0.331231773729;HMX1:0.284574395277;NKX2-2,8:0.274753058889;XCPE1{core}:0.255329056865;RUNX1..3:0.254591961767;STAT2,4,6:0.23795769523;VSX1,2:0.232111836225;FOSL2:0.216458905201;ZBTB16:0.210486315658;OCT4_SOX2{dimer}:0.209050908788;PAX6:0.185736668283;PRDM1:0.139724444548;PAX5:0.132992672019;TGIF1:0.0955175544574;TAL1_TCF{3,4,12}:0.0856257642476;TBP:0.0812688537738;NR1H4:0.077297040487;MYB:0.058923223821;SP1:0.0580124287011;POU1F1:0.0259835802251;POU5F1:0.0231859810053;NFY{A,B,C}:0.00746710071004;ARID5B:-0.0023146101077;E2F1..5:-0.00728032973677;NFE2:-0.0187057450076;KLF4:-0.0271381381949;GZF1:-0.0486595894582;ZNF143:-0.0707976136834;NFKB1_REL_RELA:-0.0719027457969;FOX{F1,F2,J1}:-0.101419574118;MYFfamily:-0.114787243965;RFX2..5_RFXANK_RFXAP:-0.120267436637;NKX2-3_NKX2-5:-0.125125693584;CEBPA,B_DDIT3:-0.127659437975;TOPORS:-0.137290588423;FOXO1,3,4:-0.140188620708;STAT1,3:-0.168197820135;GATA4:-0.173089137016;ZFP161:-0.179781828989;NRF1:-0.191255446378;FOXN1:-0.196684254764;PRRX1,2:-0.200971433461;NHLH1,2:-0.211002323666;YY1:-0.211066661798;BACH2:-0.223837236982;HBP1_HMGB_SSRP1_UBTF:-0.255112991635;SMAD1..7,9:-0.256788642539;GATA6:-0.258329981246;FOS_FOS{B,L1}_JUN{B,D}:-0.261519788072;PAX1,9:-0.263042366467;FOXP1:-0.271972122522;EGR1..3:-0.279160526195;ATF4:-0.286649392907;REST:-0.299349619405;ELK1,4_GABP{A,B1}:-0.305430806249;ALX4:-0.308911336252;NFE2L1:-0.327239617874;STAT5{A,B}:-0.327301242062;ZNF148:-0.33178606382;POU3F1..4:-0.357791252728;TFDP1:-0.383027185616;CDX1,2,4:-0.385503081593;PAX3,7:-0.399641542927;CREB1:-0.399985524232;UFEwm:-0.40550418204;HAND1,2:-0.414100468902;FOXA2:-0.416665507374;HIC1:-0.436570460933;HNF1A:-0.439648986418;NR5A1,2:-0.45930589454;NFIX:-0.475547523372;ZEB1:-0.481256214249;CRX:-0.484197303621;HSF1,2:-0.504998933324;NKX6-1,2:-0.509878532802;TFAP2{A,C}:-0.519380865405;SOX{8,9,10}:-0.525412913703;IKZF1:-0.527370730926;LMO2:-0.536432233342;LHX3,4:-0.557947902879;bHLH_family:-0.573845821488;CUX2:-0.580260272979;NR3C1:-0.58262785485;ATF5_CREB3:-0.583255804318;ALX1:-0.598253919436;PDX1:-0.607503877599;TFAP2B:-0.608054307497;ZNF423:-0.629761377599;PITX1..3:-0.634308522971;MAFB:-0.641910823115;HMGA1,2:-0.642827863105;ATF2:-0.666538388148;ZBTB6:-0.673240983056;RXR{A,B,G}:-0.674037147586;HIF1A:-0.68388541708;RORA:-0.694636402707;GFI1:-0.69866523462;HOX{A5,B5}:-0.712626791125;ONECUT1,2:-0.712648074261;TEF:-0.713450846256;RREB1:-0.732194376309;GTF2I:-0.744102580637;MAZ:-0.749411161241;MEF2{A,B,C,D}:-0.751306654592;TLX1..3_NFIC{dimer}:-0.752414825402;PAX4:-0.770729945613;FOX{D1,D2}:-0.773976951102;GFI1B:-0.774501532538;JUN:-0.811568898822;SNAI1..3:-0.822024000682;MYBL2:-0.840646771801;SRF:-0.842542607999;MTE{core}:-0.846152646773;GCM1,2:-0.854784653524;HOX{A6,A7,B6,B7}:-0.864916528124;GTF2A1,2:-0.876681570719;ADNP_IRX_SIX_ZHX:-0.877037778688;NANOG:-0.912214539538;T:-0.942707277536;ZNF238:-0.95254476181;NFATC1..3:-0.960887920453;BREu{core}:-0.964559406402;POU6F1:-1.01783915969;PATZ1:-1.02013930375;MED-1{core}:-1.03622206462;TP53:-1.03961911913;SOX2:-1.0462857249;POU2F1..3:-1.05400518657;TEAD1:-1.05481290707;ATF6:-1.08695736647;MZF1:-1.10294922165;SOX17:-1.10511314641;HOXA9_MEIS1:-1.11305368801;HOX{A4,D4}:-1.12128464694;DBP:-1.13083289517;NKX3-1:-1.13833841832;XBP1:-1.14056745484;ZIC1..3:-1.14183811248;FOX{I1,J2}:-1.1672214664;TBX4,5:-1.25926721528;RFX1:-1.31541120004;CDC5L:-1.33081197807;FOXQ1:-1.33811558424;SOX5:-1.36719937784;BPTF:-1.37545800601;EVI1:-1.44586229744;AHR_ARNT_ARNT2:-1.4620458321;AIRE:-1.51771685777;FOXM1:-1.56410471173;PBX1:-1.65129026153;LEF1_TCF7_TCF7L1,2:-1.74431749823;ZNF384:-1.91891566852;RBPJ:-1.96324874322;FOXL1:-2.14609333576;NKX2-1,4:-2.68811297328
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11389-118C3;search_select_hide=table117:FF:11389-118C3
}}
}}

Latest revision as of 17:57, 4 June 2020

Name:Macrophage - monocyte derived, donor3
Species:Human (Homo sapiens)
Library ID:CNhs12003
Sample type:primary cells
Genomic View: UCSC
RefEX:Specific genes
FANTOM CAT:1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueblood
dev stage57 years old adult
sexfemale
age57
cell typemacrophage
cell lineNA
company3HBiomedical
collaborationFANTOM5 OSC CORE (contact: Al Forrest)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberMac724
catalog number3H100-80-10
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005152
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs12003 CAGE DRX008324 DRR009196
Accession ID Hg19

Library idBAMCTSS
CNhs12003 DRZ000621 DRZ002006
Accession ID Hg38

Library idBAMCTSS
CNhs12003 DRZ011971 DRZ013356
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload

RNA-Seq Accession numbers
MethodSample accession id
sRNA-Seq  SAMD00005152
Library accession numbers

Library idMethodExp. accession idRun accession id
SRhi10006.GTTTCG sRNA-Seq DRX037086 DRR041452
Accession ID Hg19

Library idBAMCTSS
SRhi10006.GTTTCG DRZ007094


Relative expression to median (log10)

Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis-0.0579
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0.0663
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma0.181
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
C110-leukemia-chronic-Eosinophils-acute-Whole-CD34-Lymphatic0
C111-medulla-lung-trachea-testis-caudate-epididymis-throat0
C112-gastric-pancreas-temporal-duodenum-small-extraskeletal-adrenal0
C113-thyroid-throat-lung-lymph-small-colon-trachea0
C114-teratocarcinoma-medulloblastoma-carcinosarcoma-iPS-anaplastic-acute-neuroblastoma0
C115-pituitary-Neural-caudate-putamen-amygdala-medulla-hippocampus0
C116-myeloma-xeroderma-tonsil-CD19-spleen-lymph-trachea0
C117-serous-clear-kidney-neuroectodermal-mesothelioma-endometrial-Intestinal0
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C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample

JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs12003

Jaspar motifP-value
MA0002.20.00129
MA0003.10.105
MA0004.10.321
MA0006.10.328
MA0007.10.027
MA0009.10.674
MA0014.10.0631
MA0017.12.64892e-4
MA0018.20.00324
MA0019.10.453
MA0024.10.247
MA0025.10.992
MA0027.10.828
MA0028.10.906
MA0029.10.882
MA0030.10.00235
MA0031.10.0417
MA0035.20.655
MA0038.10.445
MA0039.20.0163
MA0040.10.88
MA0041.10.288
MA0042.10.562
MA0043.10.0488
MA0046.10.463
MA0047.20.62
MA0048.10.319
MA0050.13.85709e-4
MA0051.10.0213
MA0052.10.263
MA0055.10.961
MA0057.10.311
MA0058.10.0307
MA0059.10.167
MA0060.10.0165
MA0061.10.209
MA0062.20.00302
MA0065.20.00292
MA0066.10.163
MA0067.10.483
MA0068.10.00443
MA0069.10.19
MA0070.10.56
MA0071.10.0982
MA0072.10.778
MA0073.10.138
MA0074.10.0907
MA0076.10.957
MA0077.10.669
MA0078.10.617
MA0079.20.0579
MA0080.29.78276e-17
MA0081.14.45831e-4
MA0083.10.0318
MA0084.10.0253
MA0087.10.681
MA0088.10.144
MA0090.10.0142
MA0091.10.132
MA0092.10.171
MA0093.10.194
MA0099.20.1
MA0100.10.711
MA0101.10.774
MA0102.20.217
MA0103.10.709
MA0104.20.663
MA0105.10.14
MA0106.10.502
MA0107.10.581
MA0108.20.00646
MA0111.10.23
MA0112.27.7328e-4
MA0113.10.356
MA0114.10.00365
MA0115.10.256
MA0116.10.00167
MA0117.10.824
MA0119.10.753
MA0122.10.46
MA0124.10.312
MA0125.10.614
MA0131.10.253
MA0135.10.0614
MA0136.15.15171e-12
MA0137.20.269
MA0138.20.72
MA0139.10.942
MA0140.10.421
MA0141.10.00407
MA0142.10.579
MA0143.10.249
MA0144.10.0483
MA0145.10.0776
MA0146.10.00443
MA0147.10.951
MA0148.10.252
MA0149.10.124
MA0150.10.0611
MA0152.10.143
MA0153.10.00598
MA0154.10.0112
MA0155.10.712
MA0156.12.43781e-7
MA0157.10.318
MA0159.10.0197
MA0160.10.00348
MA0162.10.967
MA0163.10.00916
MA0164.10.775
MA0258.10.0104
MA0259.10.307



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs12003

Novel motifP-value
10.114
100.0414
1000.865
1010.28
1020.25
1030.16
1040.491
1050.808
1060.0768
1070.332
1080.759
1090.0057
110.0901
1100.226
1110.0302
1120.111
1130.416
1140.0617
1150.712
1160.514
1170.0415
1180.245
1190.188
120.5
1200.538
1210.594
1220.553
1230.72
1240.631
1250.0604
1260.189
1270.0863
1280.093
1290.541
130.0238
1300.802
1310.695
1320.63
1330.925
1340.561
1350.162
1360.159
1370.0169
1380.288
1390.144
140.387
1400.401
1410.516
1420.373
1430.469
1440.376
1450.681
1460.977
1470.135
1480.0633
1490.405
150.137
1500.42
1510.724
1520.0227
1530.217
1540.979
1550.142
1560.421
1570.785
1580.995
1590.367
160.127
1600.542
1610.666
1620.781
1630.679
1640.137
1650.386
1660.599
1670.565
1680.7
1690.00491
170.166
180.31
190.15
20.809
200.867
210.141
220.0991
230.368
240.0166
250.575
260.0159
270.121
280.557
290.127
30.0545
300.831
310.737
320.729
330.382
340.178
350.917
360.386
370.147
380.0744
390.973
40.689
400.117
410.172
420.772
430.107
440.0034
450.722
460.187
470.394
480.24
490.311
50.761
500.922
510.567
520.283
530.353
540.373
550.164
560.701
570.9
580.162
590.0751
60.105
600.119
610.217
620.0935
630.537
640.252
650.0562
660.946
670.292
680.993
690.466
70.275
700.086
710.0564
720.332
730.00288
740.706
750.0327
760.616
770.178
780.0669
790.199
80.12
800.378
810.258
820.394
830.95
840.476
850.0249
860.0951
870.00767
880.262
890.113
90.16
900.115
910.724
920.247
930.89
940.249
950.0272
960.247
970.955
980.501
990.886



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs12003


FANTOM5 (FF) ontology

Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0000255 (eukaryotic cell)
0000235 (macrophage)

FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000086 (human macrophage sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)

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