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MCL coexpression mm9:457

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:88202891..88202898,+p@chr10:88202891..88202898
+
Mm9::chr10:89055671..89055697,-p@chr10:89055671..89055697
-
Mm9::chr11:101797987..101797999,+p@chr11:101797987..101797999
+
Mm9::chr15:74647718..74647727,-p2@Gml
Mm9::chr16:57199200..57199210,-p@chr16:57199200..57199210
-
Mm9::chr17:24112500..24112507,-p3@Prss30
Mm9::chr17:24835294..24835316,+p4@Noxo1
Mm9::chr17:31579883..31579898,+p5@Pde9a
Mm9::chr18:15561204..15561233,-p4@Aqp4
Mm9::chr5:29550488..29550489,+p@chr5:29550488..29550489
+
Mm9::chr6:134193540..134193545,-p1@ENSMUST00000171098
Mm9::chrX:130646305..130646327,-p1@Nox1
Mm9::chrX:130646345..130646353,-p4@Nox1
Mm9::chrX:130646365..130646375,-p3@Nox1
Mm9::chrX:130646391..130646412,-p2@Nox1
Mm9::chrX:136330909..136330938,-p@chrX:136330909..136330938
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0006801superoxide metabolic process0.000219149897867761
GO:0006800oxygen and reactive oxygen species metabolic process0.000423256398957932
GO:0016176superoxide-generating NADPH oxidase activator activity0.00847140396894049
GO:0042554superoxide release0.00847140396894049
GO:0050664oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor0.00847140396894049
GO:0016175superoxide-generating NADPH oxidase activity0.00847140396894049
GO:0030104water homeostasis0.010745982262163
GO:00475553',5'-cyclic-GMP phosphodiesterase activity0.010745982262163
GO:0018987osmoregulation0.010745982262163
GO:0015250water channel activity0.010745982262163
GO:0005372water transporter activity0.010745982262163
GO:0006833water transport0.010745982262163
GO:0042044fluid transport0.010745982262163
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity0.021747829321369
GO:0004112cyclic-nucleotide phosphodiesterase activity0.0219858569324737
GO:0008081phosphoric diester hydrolase activity0.0490826525886069
GO:0016651oxidoreductase activity, acting on NADH or NADPH0.0490826525886069
GO:0050878regulation of body fluid levels0.0491491133962644



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
intestine1.24e-2631
mucosa3.22e-2615
intestinal mucosa2.43e-1913
anatomical wall2.43e-1913
wall of intestine2.43e-1913
gastrointestinal system mucosa2.43e-1913
gastrointestinal system3.32e-1947
small intestine2.73e-164
organ component layer8.52e-1624
ileal mucosa5.62e-133
ileum5.62e-133
mucosa of small intestine5.62e-133
wall of small intestine5.62e-133
epithelium of mucosa2.09e-119
gastrointestinal system epithelium2.09e-119
intestinal epithelium2.09e-119
gut-associated lymphoid tissue1.52e-092
mucosa-associated lymphoid tissue1.52e-092
lymphoid tissue1.52e-092
simple columnar epithelium2.71e-0911
colon5.67e-092
large intestine5.67e-092
digestive system2.66e-08116
digestive tract2.66e-08116
primitive gut2.66e-08116
endoderm-derived structure4.16e-08118
endoderm4.16e-08118
presumptive endoderm4.16e-08118


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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