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MCL coexpression mm9:781

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:21501144..21501147,+p@chr11:21501144..21501147
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Mm9::chr11:48715513..48715546,-p@chr11:48715513..48715546
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Mm9::chr11:6129264..6129275,-p@chr11:6129264..6129275
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Mm9::chr11:9019226..9019233,+p@chr11:9019226..9019233
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Mm9::chr11:9019282..9019299,+p@chr11:9019282..9019299
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Mm9::chr15:77490274..77490279,-p@chr15:77490274..77490279
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Mm9::chr18:73975357..73975368,-p3@Me2
Mm9::chr19:53102858..53102869,-p@chr19:53102858..53102869
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Mm9::chr9:31720903..31720918,-p2@Barx2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0000122negative regulation of transcription from RNA polymerase II promoter0.00365576547784741
GO:0045892negative regulation of transcription, DNA-dependent0.00365576547784741
GO:0016481negative regulation of transcription0.00365576547784741
GO:0045934negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.00365576547784741
GO:0042637catagen0.00365576547784741
GO:0031324negative regulation of cellular metabolic process0.00365576547784741
GO:0009892negative regulation of metabolic process0.00400373694120981
GO:0006357regulation of transcription from RNA polymerase II promoter0.00456441499641985
GO:0005667transcription factor complex0.00456441499641985
GO:0006366transcription from RNA polymerase II promoter0.00456441499641985
GO:0044451nucleoplasm part0.00635773056744951
GO:0005654nucleoplasm0.00640120353318183
GO:0031981nuclear lumen0.00835083855626479
GO:0048820hair follicle maturation0.00863300937840844
GO:0031974membrane-enclosed lumen0.00863300937840844
GO:0043233organelle lumen0.00863300937840844
GO:0048523negative regulation of cellular process0.0101479934017225
GO:0048519negative regulation of biological process0.011067884623619
GO:0044428nuclear part0.0128492932728319
GO:0045445myoblast differentiation0.0161890987055238
GO:0022404molting cycle process0.0161890987055238
GO:0001942hair follicle development0.0161890987055238
GO:0022405hair cycle process0.0161890987055238
GO:0042633hair cycle0.0161890987055238
GO:0042303molting cycle0.0161890987055238
GO:0003714transcription corepressor activity0.0202653465137349
GO:0042692muscle cell differentiation0.0207599354898422
GO:0048741skeletal muscle fiber development0.0207599354898422
GO:0048747muscle fiber development0.0207599354898422
GO:0043234protein complex0.020873176648202
GO:0006355regulation of transcription, DNA-dependent0.0230245297652552
GO:0006351transcription, DNA-dependent0.0230245297652552
GO:0021700developmental maturation0.0230245297652552
GO:0032774RNA biosynthetic process0.0230245297652552
GO:0003677DNA binding0.0230245297652552
GO:0007519skeletal muscle development0.0230245297652552
GO:0008544epidermis development0.0230245297652552
GO:0045449regulation of transcription0.0230245297652552
GO:0003682chromatin binding0.0230245297652552
GO:0019219regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0230245297652552
GO:0007398ectoderm development0.0230245297652552
GO:0006350transcription0.0230245297652552
GO:0032991macromolecular complex0.0231208919643697
GO:0010468regulation of gene expression0.0234789215736499
GO:0031323regulation of cellular metabolic process0.0248777568436999
GO:0014706striated muscle development0.0249088824294402
GO:0007275multicellular organismal development0.0249298079320954
GO:0019222regulation of metabolic process0.0250795011298027
GO:0016070RNA metabolic process0.0255360665361971
GO:0003712transcription cofactor activity0.0255360665361971
GO:0044446intracellular organelle part0.0261352402748791
GO:0044422organelle part0.0261352402748791
GO:0016564transcription repressor activity0.027089289112185
GO:0007517muscle development0.0288363997579811
GO:0008134transcription factor binding0.031875321855894
GO:0010467gene expression0.0324322052668077
GO:0003676nucleic acid binding0.0334193720851622
GO:0032502developmental process0.0349805674959158
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.037496913465151
GO:0050794regulation of cellular process0.0424056232662334
GO:0009888tissue development0.0430751330345371



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
intestine2.04e-3731
mucosa5.17e-3715
intestinal mucosa6.08e-3113
anatomical wall6.08e-3113
wall of intestine6.08e-3113
gastrointestinal system mucosa6.08e-3113
gastrointestinal system1.84e-2347
organ component layer3.24e-2224
epithelium of mucosa6.35e-189
gastrointestinal system epithelium6.35e-189
intestinal epithelium6.35e-189
small intestine9.58e-154
simple columnar epithelium1.63e-1411
ileal mucosa1.06e-113
ileum1.06e-113
mucosa of small intestine1.06e-113
wall of small intestine1.06e-113
digestive system1.99e-09116
digestive tract1.99e-09116
primitive gut1.99e-09116
endoderm-derived structure3.37e-09118
endoderm3.37e-09118
presumptive endoderm3.37e-09118
gut-associated lymphoid tissue1.31e-072
mucosa-associated lymphoid tissue1.31e-072
lymphoid tissue1.31e-072
subdivision of digestive tract1.66e-07114


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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