Preadipocyte to adipocyte: Difference between revisions
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|species=Human (Homo sapiens) | |species=Human (Homo sapiens) | ||
|zenbu_config=http://fantom.gsc.riken.jp/zenbu/gLyphs/#config=09CK2sBgH92pWLE_iM7HN | |zenbu_config=http://fantom.gsc.riken.jp/zenbu/gLyphs/#config=09CK2sBgH92pWLE_iM7HN | ||
|TCOverview=Adipose tissue can account for between 5% (lean athletes) and 60% (morbidly obese) of total body mass, making it one of the most plastic organs in the body [8]. In response to changed nutritional status, both adipocyte cell number and size change and even under stable conditions as much as 10% of the adipocytes are turned over annually [1,2]. Thus the birth of new adipocytes from precursor cells (adipogenesis) is central for a functional fat tissue.<br> | |||
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References:<br> | |||
[1] Dynamics of fat cell turnover in humans. Spalding KL et al, Nature, 2008, vol 453, p783-787. PMID:18454136<br> | |||
[2] Adipocyte turnover:relevance to human adiopose tissue morphology- Arner E et al, Diabetes, 2010,59(1):105-9. PMID:19846802<br> | |||
}} | }} | ||
Revision as of 10:14, 9 December 2014
| Series: | IN_VITRO DIFFERENTIATION SERIES |
|---|---|
| Species: | Human (Homo sapiens) |
| Genomic View: | Zenbu |
| Expression table: | [{{{tet_config}}} FILE] |
| Link to TET: | [{{{tet_file}}} TET] |
| Sample providers : | Peter Arner |
| Germ layer: | {{{germ_layer}}} |
| Primary cells or cell line: | {{{primary_cells}}} |
| Time span: | {{{time_span}}} |
| Number of time points: | {{{number_time_points}}} |
| Overview |
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|
Adipose tissue can account for between 5% (lean athletes) and 60% (morbidly obese) of total body mass, making it one of the most plastic organs in the body [8]. In response to changed nutritional status, both adipocyte cell number and size change and even under stable conditions as much as 10% of the adipocytes are turned over annually [1,2]. Thus the birth of new adipocytes from precursor cells (adipogenesis) is central for a functional fat tissue. |
| Sample description |
|---|
|
{{{TCSample_description}}} |
| Quality control |
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|
{{{TCQuality_control}}} |
Profiled time course samples
Only samples that passed quality controls (Arner et al. 2015) are shown here. The entire set of samples are downloadable from FANTOM5 human / mouse samples
| 13019-139D4 | Adipocyte differentiation | day04 | donor1 |
| 13020-139D5 | Adipocyte differentiation | day08 | donor1 |
| 13021-139D6 | Adipocyte differentiation | day12 | donor1 |
| 13022-139D7 | Adipocyte differentiation | day04 | donor2 |
| 13023-139D8 | Adipocyte differentiation | day08 | donor2 |
| 13024-139D9 | Adipocyte differentiation | day12 | donor2 |
| 13025-139E1 | Adipocyte differentiation | day04 | donor3 |
| 13026-139E2 | Adipocyte differentiation | day08 | donor3 |
| 13027-139E3 | Adipocyte differentiation | day12 | donor3 |
| 13028-139E4 | Adipocyte differentiation | day04 | donor4 |
| 13029-139E5 | Adipocyte differentiation | day08 | donor4 |
| 13030-139E6 | Adipocyte differentiation | day12 | donor4 |
