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UBERON:0001803

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Name:epithelium of lens
Definition:"The cells of the lens epithelium regulate most of the homeostatic functions of the lens.[6] As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions." [Wikipedia:Lens_(anatomy)#Lens_Epithelium]
Xrefs:
links:

BTO:0001873
FMA:58871
MA:0001301
SCTID:362523006
TAO:0001326
XAO:0004094

ZFA:0001326
Synonyms: "epithelial tissue of eye lens" EXACT [OBOL:automatic]
"epithelial tissue of lens" EXACT [OBOL:automatic]
"epithelium lentis" EXACT [FMA:58871, FMA:TA]
"epithelium of eye lens" EXACT [OBOL:automatic]
"eye lens epithelial tissue" EXACT [OBOL:automatic]
"eye lens epithelium" EXACT [OBOL:automatic]
"lens epithelial tissue" EXACT [OBOL:automatic]
"lens epithelium" EXACT []
Comments:Usage notes: this class is the superclass of the anterior epithelium and equatorial epithlium, although the term 'lens epithelium' may refer specifically to the former
Alt_id: UBERON:FMA_58871-MA_0001301-ZFA_0001326
Subset: vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0000484(simple cuboidal epithelium),UBERON:0007625(pigment epithelium of eye),UBERON:0010371(ecto-epithelium)



Children

part of:CL:0002224 (lens epithelial cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001803 (epithelium of lens), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
1.41e-88FFCP PHASE2:Hg19::chr22:25595823..25595826,+#_83d2b9028d42a0176aed984c351cfb53p1@CRYBB3
1.41e-88FFCP PHASE1:Hg19::chr22:25595823..25595826,+#_83d2b9028d42a0176aed984c351cfb53p1@CRYBB3
3.32e-74FFCP PHASE2:Hg19::chr22:25615600..25615611,+#_fc93bec4341434b7f9026f77ea5c26d2p1@CRYBB2
3.32e-74FFCP PHASE1:Hg19::chr22:25615600..25615611,+#_fc93bec4341434b7f9026f77ea5c26d2p1@CRYBB2
5.48e-74FFCP PHASE1:Hg19::chr19:51891222..51891233,-#_afaaa2e0f09d186d3e6f652807941ab4p1@LIM2
5.48e-74FFCP PHASE2:Hg19::chr19:51891222..51891233,-#_afaaa2e0f09d186d3e6f652807941ab4p1@LIM2
3.8e-56FFCP PHASE2:Hg19::chr22:27017921..27017928,+#_bbb3aa727743016e315b7819325987d5p1@CRYBA4
3.8e-56FFCP PHASE1:Hg19::chr22:27017921..27017928,+#_bbb3aa727743016e315b7819325987d5p1@CRYBA4
3.1e-50FFCP PHASE1:Hg19::chr13:104778247..104778293,+#_21b3868d1fa32818d4e34ce31952615ep@chr13:104778247..104778293, +
3.1e-50FFCP PHASE2:Hg19::chr20:61204240..61204241,+#_21b3868d1fa32818d4e34ce31952615ep@chr20:61204240..61204241, +
3.1e-50FFCP PHASE2:Hg19::chr13:104778247..104778293,+#_21b3868d1fa32818d4e34ce31952615ep@chr13:104778247..104778293, +
3.1e-50FFCP PHASE1:Hg19::chr20:61204240..61204241,+#_21b3868d1fa32818d4e34ce31952615ep@chr20:61204240..61204241, +
5.14e-50FFCP PHASE2:Hg19::chr21:44592820..44592840,-#_7dc0b6ba3c7ab60d734c8495dc4f43a0p2@CU686889
5.14e-50FFCP PHASE1:Hg19::chr21:44592820..44592840,-#_7dc0b6ba3c7ab60d734c8495dc4f43a0p2@CU686889
5.14e-50FFCP PHASE1:Hg19::chr14:37642016..37642022,-#_7dc0b6ba3c7ab60d734c8495dc4f43a0p7@SLC25A21
5.14e-50FFCP PHASE2:Hg19::chr14:37642016..37642022,-#_7dc0b6ba3c7ab60d734c8495dc4f43a0p7@SLC25A21
6.6e-50FFCP PHASE1:Hg19::chr12:132475501..132475504,+#_2456163f6b01187978daefc432facf6cp@chr12:132475501..132475504, +
6.6e-50FFCP PHASE2:Hg19::chr21:44592842..44592867,-#_2456163f6b01187978daefc432facf6cp1@CU686889
6.6e-50FFCP PHASE1:Hg19::chr21:44592842..44592867,-#_2456163f6b01187978daefc432facf6cp1@CU686889
6.6e-50FFCP PHASE2:Hg19::chr21:44589339..44589372,-#_2456163f6b01187978daefc432facf6cp@chr21:44589339..44589372, -
6.6e-50FFCP PHASE1:Hg19::chr21:44589339..44589372,-#_2456163f6b01187978daefc432facf6cp@chr21:44589339..44589372, -
6.6e-50FFCP PHASE2:Hg19::chr12:132475501..132475504,+#_2456163f6b01187978daefc432facf6cp@chr12:132475501..132475504, +
6.27e-44FFCP PHASE1:Hg19::chr11:31827535..31827565,-#_963c5f4fb694c2766ac0c5b7e09076bep11@PAX6
6.27e-44FFCP PHASE2:Hg19::chr11:31827535..31827565,-#_963c5f4fb694c2766ac0c5b7e09076bep11@PAX6
1.92e-41FFCP PHASE1:Hg19::chr3:186262166..186262170,-#_a51f7378f7dd20e2f9fa6296da7b524bp1@CRYGS
1.92e-41FFCP PHASE2:Hg19::chr3:186262166..186262170,-#_a51f7378f7dd20e2f9fa6296da7b524bp1@CRYGS
4.94e-40FFCP PHASE2:Hg19::chr5:112173525..112173532,+#_af0d00502530f4631d4bfcfb8f9d78eep@chr5:112173525..112173532, +
4.94e-40FFCP PHASE1:Hg19::chr5:112173525..112173532,+#_af0d00502530f4631d4bfcfb8f9d78eep@chr5:112173525..112173532, +
1.62e-37FFCP PHASE2:Hg19::chr1:29586692..29586705,+#_1d671919c8779e3efcd5f67ccb16c63cp7@PTPRU
1.62e-37FFCP PHASE1:Hg19::chr1:29586692..29586705,+#_1d671919c8779e3efcd5f67ccb16c63cp7@PTPRU
2.1e-35FFCP PHASE2:Hg19::chr14:60975644..60975673,+#_8ed164c8b70ea57163a0c78f061e2c99p3@SIX6
2.1e-35FFCP PHASE1:Hg19::chr14:60975644..60975673,+#_8ed164c8b70ea57163a0c78f061e2c99p3@SIX6
6.73e-35FFCP PHASE1:Hg19::chr14:60975871..60975880,+#_50e27168cba746cb23075f08939a294ep4@SIX6
6.73e-35FFCP PHASE2:Hg19::chr14:60975871..60975880,+#_50e27168cba746cb23075f08939a294ep4@SIX6
5.06e-34FFCP PHASE2:Hg19::chr11:31667372..31667383,-#_c92b7421b6ed38a50d4b6dc2b26bbe8ep@chr11:31667372..31667383, -
5.06e-34FFCP PHASE1:Hg19::chr11:31667372..31667383,-#_c92b7421b6ed38a50d4b6dc2b26bbe8ep@chr11:31667372..31667383, -
8.36e-34FFCP PHASE2:Hg19::chr19:1470631..1470648,-#_2fcc79b2e9ca8154ee385a242e3cc2e5p@chr19:1470631..1470648, -
8.36e-34FFCP PHASE1:Hg19::chr19:1470631..1470648,-#_2fcc79b2e9ca8154ee385a242e3cc2e5p@chr19:1470631..1470648, -
5.55e-33FFCP PHASE2:Hg19::chr21:44589135..44589151,+#_6249b2b137aa96490e21135eb4d817ccp1@CRYAA
5.55e-33FFCP PHASE1:Hg19::chr21:44589135..44589151,+#_6249b2b137aa96490e21135eb4d817ccp1@CRYAA
9.55e-33FFCP PHASE1:Hg19::chr17:27573875..27573878,+#_3a21608e25cf2a4f4ddfd5539b1c4a22p1@CRYBA1
9.55e-33FFCP PHASE2:Hg19::chr17:27573875..27573878,+#_3a21608e25cf2a4f4ddfd5539b1c4a22p1@CRYBA1
2.74e-29FFCP PHASE2:Hg19::chr2:45168589..45168601,-#_3dd4c5215f609eea171a44e1369c6885p2@ENST00000456467
2.74e-29FFCP PHASE1:Hg19::chr2:45168589..45168601,-#_3dd4c5215f609eea171a44e1369c6885p2@ENST00000456467
3.65e-29FFCP PHASE2:Hg19::chr7:107883678..107883689,-#_ac2df97610e2795556a5e9bd4981b980p13@NRCAM
3.65e-29FFCP PHASE1:Hg19::chr7:107883678..107883689,-#_ac2df97610e2795556a5e9bd4981b980p13@NRCAM
7.46e-29FFCP PHASE2:Hg19::chr13:114202163..114202178,+#_ac2ce84949e73895a3a0cf34a0a37a54p@chr13:114202163..114202178, +
7.46e-29FFCP PHASE1:Hg19::chr13:114202163..114202178,+#_ac2ce84949e73895a3a0cf34a0a37a54p@chr13:114202163..114202178, +
1.36e-28FFCP PHASE2:Hg19::chr3:173116225..173116242,+#_95d7452e35b0ffe081cff7da7e13a466p10@NLGN1
1.36e-28FFCP PHASE1:Hg19::chr3:173116225..173116242,+#_95d7452e35b0ffe081cff7da7e13a466p10@NLGN1
2.64e-27FFCP PHASE2:Hg19::chr2:45169233..45169244,+#_0f2bc71b4b7c43f3d6fc244504c5d295p10@SIX3
2.64e-27FFCP PHASE1:Hg19::chr2:45169233..45169244,+#_0f2bc71b4b7c43f3d6fc244504c5d295p10@SIX3
8.39e-27FFCP PHASE2:Hg19::chr14:60975858..60975869,+#_0855810de08f775f4a3511b131a7b3acp2@SIX6
8.39e-27FFCP PHASE1:Hg19::chr14:60975858..60975869,+#_0855810de08f775f4a3511b131a7b3acp2@SIX6
5.56e-26FFCP PHASE2:Hg19::chr3:150690809..150690822,-#_2898fb4781f15516b2d88b0ade52783fp3@CLRN1
5.56e-26FFCP PHASE1:Hg19::chr3:150690809..150690822,-#_2898fb4781f15516b2d88b0ade52783fp3@CLRN1
5.56e-26FFCP PHASE2:Hg19::chr9:75848662..75848671,-#_2898fb4781f15516b2d88b0ade52783fp@chr9:75848662..75848671, -
5.56e-26FFCP PHASE1:Hg19::chr1:147374915..147374932,+#_2898fb4781f15516b2d88b0ade52783fp1@GJA8
5.56e-26FFCP PHASE1:Hg19::chr9:75848662..75848671,-#_2898fb4781f15516b2d88b0ade52783fp@chr9:75848662..75848671, -
5.56e-26FFCP PHASE2:Hg19::chr1:147374915..147374932,+#_2898fb4781f15516b2d88b0ade52783fp1@GJA8
5.56e-26FFCP PHASE2:Hg19::chr20:35861148..35861151,+#_2898fb4781f15516b2d88b0ade52783fp@chr20:35861148..35861151, +
5.56e-26FFCP PHASE1:Hg19::chr20:35861148..35861151,+#_2898fb4781f15516b2d88b0ade52783fp@chr20:35861148..35861151, +
5.56e-26FFCP PHASE1:Hg19::chr19:40920692..40920700,-#_2898fb4781f15516b2d88b0ade52783fp@chr19:40920692..40920700, -
5.56e-26FFCP PHASE2:Hg19::chrX:43587410..43587413,+#_2898fb4781f15516b2d88b0ade52783fp@chrX:43587410..43587413, +
5.56e-26FFCP PHASE1:Hg19::chrX:43587410..43587413,+#_2898fb4781f15516b2d88b0ade52783fp@chrX:43587410..43587413, +
5.56e-26FFCP PHASE2:Hg19::chr19:40920692..40920700,-#_2898fb4781f15516b2d88b0ade52783fp@chr19:40920692..40920700, -
7.14e-26FFCP PHASE2:Hg19::chr10:73406056..73406065,+#_926d52a6a69bbb21e5552b130ab23a26p@chr10:73406056..73406065, +
7.14e-26FFCP PHASE1:Hg19::chr11:65361417..65361421,-#_926d52a6a69bbb21e5552b130ab23a26p2@KCNK7
7.14e-26FFCP PHASE2:Hg19::chr7:123198284..123198329,-#_926d52a6a69bbb21e5552b130ab23a26p3@NDUFA5
7.14e-26FFCP PHASE1:Hg19::chr16:85617064..85617073,-#_926d52a6a69bbb21e5552b130ab23a26p@chr16:85617064..85617073, -
7.14e-26FFCP PHASE2:Hg19::chr9:100057272..100057276,+#_926d52a6a69bbb21e5552b130ab23a26p@chr9:100057272..100057276, +
7.14e-26FFCP PHASE2:Hg19::chr21:44592512..44592521,+#_926d52a6a69bbb21e5552b130ab23a26p@chr21:44592512..44592521, +
7.14e-26FFCP PHASE1:Hg19::chr7:123198284..123198329,-#_926d52a6a69bbb21e5552b130ab23a26p3@NDUFA5
7.14e-26FFCP PHASE2:Hg19::chr21:36253916..36253918,-#_926d52a6a69bbb21e5552b130ab23a26p@chr21:36253916..36253918, -
7.14e-26FFCP PHASE1:Hg19::chr9:100057272..100057276,+#_926d52a6a69bbb21e5552b130ab23a26p@chr9:100057272..100057276, +
7.14e-26FFCP PHASE1:Hg19::chr21:44592512..44592521,+#_926d52a6a69bbb21e5552b130ab23a26p@chr21:44592512..44592521, +
7.14e-26FFCP PHASE2:Hg19::chr3:156322310..156322314,-#_926d52a6a69bbb21e5552b130ab23a26p@chr3:156322310..156322314, -
7.14e-26FFCP PHASE1:Hg19::chr19:41727698..41727705,+#_926d52a6a69bbb21e5552b130ab23a26p@chr19:41727698..41727705, +
7.14e-26FFCP PHASE2:Hg19::chr16:85617064..85617073,-#_926d52a6a69bbb21e5552b130ab23a26p@chr16:85617064..85617073, -
7.14e-26FFCP PHASE1:Hg19::chr21:36253916..36253918,-#_926d52a6a69bbb21e5552b130ab23a26p@chr21:36253916..36253918, -
7.14e-26FFCP PHASE1:Hg19::chr3:156322310..156322314,-#_926d52a6a69bbb21e5552b130ab23a26p@chr3:156322310..156322314, -
7.14e-26FFCP PHASE2:Hg19::chr12:56848437..56848442,-#_926d52a6a69bbb21e5552b130ab23a26p1@MIP
7.14e-26FFCP PHASE1:Hg19::chr13:72440726..72440736,-#_926d52a6a69bbb21e5552b130ab23a26p19@DACH1
7.14e-26FFCP PHASE2:Hg19::chr13:44875179..44875188,-#_926d52a6a69bbb21e5552b130ab23a26p@chr13:44875179..44875188, -
7.14e-26FFCP PHASE2:Hg19::chr19:41727698..41727705,+#_926d52a6a69bbb21e5552b130ab23a26p@chr19:41727698..41727705, +
7.14e-26FFCP PHASE2:Hg19::chr21:44592626..44592635,-#_926d52a6a69bbb21e5552b130ab23a26p5@CU686889
7.14e-26FFCP PHASE1:Hg19::chr19:17137781..17137792,-#_926d52a6a69bbb21e5552b130ab23a26p6@CPAMD8
7.14e-26FFCP PHASE1:Hg19::chr21:44592626..44592635,-#_926d52a6a69bbb21e5552b130ab23a26p5@CU686889
7.14e-26FFCP PHASE2:Hg19::chr4:140656282..140656285,-#_926d52a6a69bbb21e5552b130ab23a26p@chr4:140656282..140656285, -
7.14e-26FFCP PHASE2:Hg19::chr11:65361417..65361421,-#_926d52a6a69bbb21e5552b130ab23a26p2@KCNK7
7.14e-26FFCP PHASE2:Hg19::chr19:17137781..17137792,-#_926d52a6a69bbb21e5552b130ab23a26p6@CPAMD8
7.14e-26FFCP PHASE1:Hg19::chr4:140656282..140656285,-#_926d52a6a69bbb21e5552b130ab23a26p@chr4:140656282..140656285, -
7.14e-26FFCP PHASE2:Hg19::chr16:17563573..17563582,+#_926d52a6a69bbb21e5552b130ab23a26p@chr16:17563573..17563582, +
7.14e-26FFCP PHASE1:Hg19::chr10:73406056..73406065,+#_926d52a6a69bbb21e5552b130ab23a26p@chr10:73406056..73406065, +
7.14e-26FFCP PHASE2:Hg19::chr21:44592750..44592758,-#_926d52a6a69bbb21e5552b130ab23a26p4@CU686889
7.14e-26FFCP PHASE2:Hg19::chr2:45154282..45154288,-#_926d52a6a69bbb21e5552b130ab23a26p@chr2:45154282..45154288, -
7.14e-26FFCP PHASE1:Hg19::chr21:44592750..44592758,-#_926d52a6a69bbb21e5552b130ab23a26p4@CU686889
7.14e-26FFCP PHASE2:Hg19::chr5:124468141..124468176,-#_926d52a6a69bbb21e5552b130ab23a26p@chr5:124468141..124468176, -
7.14e-26FFCP PHASE2:Hg19::chr5:45038620..45038622,+#_926d52a6a69bbb21e5552b130ab23a26p@chr5:45038620..45038622, +
7.14e-26FFCP PHASE1:Hg19::chr2:45154282..45154288,-#_926d52a6a69bbb21e5552b130ab23a26p@chr2:45154282..45154288, -