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UBERON:0001995

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Name:fibrocartilage
Definition:"Cartilage tissue intermediate between hyaline cartilage and dense connective tissue; contains of abundant collagen fibers; chondrocytes often arranged in columns[VAO]. A mixture of white fibrous tissue and cartilaginous tissue in various proportions. It owes its flexibility and toughness to the former of these constituents, and its elasticity to the latter. It is the only type of cartilage that contains type I collagen in addition to the normal type II[WP]. Cartilage (tissue) which consists of chondrocytes and collagen, the intercellular matrix of which is an amorphous gel without a well-defined perichondrium[FMA]." [FMA:64784, VAO:0000103, Wikipedia:Fibrocartilage]
Xrefs:
links:

FMA:64784
galen:Fibrocartilage
[ 200px-Gray295.png 200px-Gray295.png]
MA:0000108
ncithesaurus:Fibrocartilage
SCTID:91685003
VAO:0000103

XAO:0004028
Comments:The white fibrocartilages admit of arrangement into four groups窶琶nterarticular, connecting, circumferential, and stratiform -- WP. TODO: add mineralized
Alt_id: UBERON:FMA_64784-MA_0000108
Subset: uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0002418(cartilage tissue)



Children

is a:UBERON:0006444 (annulus fibrosus)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001995 (fibrocartilage), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
5.68e-99FFCP PHASE1:Hg19::chr1:78769549..78769554,+#_10864a32a4801fd0f053c5e93afb7c9ep5@PTGFR
5.68e-99FFCP PHASE2:Hg19::chr1:78769549..78769554,+#_10864a32a4801fd0f053c5e93afb7c9ep5@PTGFR
1.55e-98FFCP PHASE1:Hg19::chr13:24914614..24914622,-#_38c4065d531607dc6f941c13ff673639p@chr13:24914614..24914622, -
1.55e-98FFCP PHASE2:Hg19::chr13:24914614..24914622,-#_38c4065d531607dc6f941c13ff673639p@chr13:24914614..24914622, -
2.34e-79FFCP PHASE2:Hg19::chr9:114135497..114135526,-#_cf7f20fb091d2243029b5ba1dd2760d5p@chr9:114135497..114135526, -
2.34e-79FFCP PHASE1:Hg19::chr9:114135497..114135526,-#_cf7f20fb091d2243029b5ba1dd2760d5p@chr9:114135497..114135526, -
1.45e-66FFCP PHASE2:Hg19::chr3:174737010..174737023,+#_da823eeea2e97f058396ce5e7bb99d1cp@chr3:174737010..174737023, +
1.45e-66FFCP PHASE1:Hg19::chr3:174737010..174737023,+#_da823eeea2e97f058396ce5e7bb99d1cp@chr3:174737010..174737023, +
2.84e-66FFCP PHASE1:Hg19::chr2:241897189..241897221,-#_0fa265afc817956f71703f7cacdb8dccp@chr2:241897189..241897221, -
2.84e-66FFCP PHASE2:Hg19::chr2:241897189..241897221,-#_0fa265afc817956f71703f7cacdb8dccp@chr2:241897189..241897221, -
1.13e-57FFCP PHASE2:Hg19::chr20:21687193..21687206,+#_e88b2246d02b1f805c9a9b2b62d470ebp4@PAX1
1.13e-57FFCP PHASE2:Hg19::chr10:81923378..81923389,-#_e88b2246d02b1f805c9a9b2b62d470ebp@chr10:81923378..81923389, -
1.13e-57FFCP PHASE1:Hg19::chr20:21687193..21687206,+#_e88b2246d02b1f805c9a9b2b62d470ebp4@PAX1
1.13e-57FFCP PHASE2:Hg19::chr20:21687260..21687270,+#_e88b2246d02b1f805c9a9b2b62d470ebp3@PAX1
1.13e-57FFCP PHASE1:Hg19::chr20:21687260..21687270,+#_e88b2246d02b1f805c9a9b2b62d470ebp3@PAX1
1.13e-57FFCP PHASE1:Hg19::chr10:81923378..81923389,-#_e88b2246d02b1f805c9a9b2b62d470ebp@chr10:81923378..81923389, -
1.14e-50FFCP PHASE2:Hg19::chr4:13546583..13546593,-#_858f989291147beddd38f7b493069d16p3@NKX3-2
1.14e-50FFCP PHASE1:Hg19::chr4:13546583..13546593,-#_858f989291147beddd38f7b493069d16p3@NKX3-2
1.46e-50FFCP PHASE2:Hg19::chr4:13546130..13546145,-#_e81797858c0c7bf1a02d29a7143cf4fbp4@NKX3-2
1.46e-50FFCP PHASE1:Hg19::chr4:13546130..13546145,-#_e81797858c0c7bf1a02d29a7143cf4fbp4@NKX3-2
2.74e-50FFCP PHASE2:Hg19::chr16:4421890..4421912,-#_bcf0b56b2310fd5038a3e3ad34464dcfp@chr16:4421890..4421912, -
2.74e-50FFCP PHASE1:Hg19::chr16:4421890..4421912,-#_bcf0b56b2310fd5038a3e3ad34464dcfp@chr16:4421890..4421912, -
3.19e-45FFCP PHASE2:Hg19::chr2:241897125..241897142,-#_867dd4387f6c86c1ebb45ac654e578b2p@chr2:241897125..241897142, -
3.19e-45FFCP PHASE1:Hg19::chr2:241897125..241897142,-#_867dd4387f6c86c1ebb45ac654e578b2p@chr2:241897125..241897142, -
1.22e-44FFCP PHASE2:Hg19::chr3:80727046..80727051,-#_c2c85d5ff902a1fb42e4ce117dc42487p@chr3:80727046..80727051, -
1.22e-44FFCP PHASE1:Hg19::chr3:80727046..80727051,-#_c2c85d5ff902a1fb42e4ce117dc42487p@chr3:80727046..80727051, -
5.99e-41FFCP PHASE2:Hg19::chr5:30104176..30104187,-#_d59de1de4c10df6e0e59e3ad2c218677p@chr5:30104176..30104187, -
5.99e-41FFCP PHASE1:Hg19::chr5:30104176..30104187,-#_d59de1de4c10df6e0e59e3ad2c218677p@chr5:30104176..30104187, -
3.01e-40FFCP PHASE2:Hg19::chr1:19778678..19778689,-#_628c3dc43f0f8e39be070f8324431629p@chr1:19778678..19778689, -
3.01e-40FFCP PHASE1:Hg19::chr1:19778678..19778689,-#_628c3dc43f0f8e39be070f8324431629p@chr1:19778678..19778689, -
1.3e-37FFCP PHASE2:Hg19::chr20:21695435..21695452,+#_224440c77e5add18800cf96248de5c9bp@chr20:21695435..21695452, +
1.3e-37FFCP PHASE1:Hg19::chr20:21695435..21695452,+#_224440c77e5add18800cf96248de5c9bp@chr20:21695435..21695452, +
3.94e-37FFCP PHASE2:Hg19::chr16:70795228..70795237,+#_6fb0ca073b96730c7c847ee0d482fa3fp@chr16:70795228..70795237, +
3.94e-37FFCP PHASE1:Hg19::chr16:70795228..70795237,+#_6fb0ca073b96730c7c847ee0d482fa3fp@chr16:70795228..70795237, +
8.2e-37FFCP PHASE1:Hg19::chr14:23574186..23574212,-#_83881af1a61fbef6082456c4b36fb94fp1@uc010aki.1
8.2e-37FFCP PHASE2:Hg19::chr14:23574186..23574212,-#_83881af1a61fbef6082456c4b36fb94fp1@uc010aki.1
1.18e-36FFCP PHASE2:Hg19::chr8:27455513..27455516,+#_26c35ec6483f0fba01cc26cff47aee2ap7@CU679734
1.18e-36FFCP PHASE1:Hg19::chr8:27455513..27455516,+#_26c35ec6483f0fba01cc26cff47aee2ap7@CU679734
7.05e-34FFCP PHASE2:Hg19::chr14:23574164..23574179,-#_17f4b949ef8eae7e967df1038ce138ebp3@uc010aki.1
7.05e-34FFCP PHASE1:Hg19::chr14:23574164..23574179,-#_17f4b949ef8eae7e967df1038ce138ebp3@uc010aki.1
8.05e-30FFCP PHASE1:Hg19::chr11:66724317..66724340,-#_4984ce18d42359a2a53afd7bcbdca601p@chr11:66724317..66724340, -
8.05e-30FFCP PHASE2:Hg19::chr11:66724317..66724340,-#_4984ce18d42359a2a53afd7bcbdca601p@chr11:66724317..66724340, -
2.22e-29FFCP PHASE2:Hg19::chr2:53161632..53161661,-#_c4198bcce76b8922b336a308a9b874e9p@chr2:53161632..53161661, -
2.22e-29FFCP PHASE1:Hg19::chr2:53161632..53161661,-#_c4198bcce76b8922b336a308a9b874e9p@chr2:53161632..53161661, -
5.41e-28FFCP PHASE2:Hg19::chr2:242004292..242004308,+#_7ce29419ef75f330425168994cbac515p15@SNED1
5.41e-28FFCP PHASE1:Hg19::chr2:242004292..242004308,+#_7ce29419ef75f330425168994cbac515p15@SNED1
7.1e-28FFCP PHASE2:Hg19::chr1:19811132..19811155,-#_a28ae4e59a5462693944c19aef901a44p20@CAPZB
7.1e-28FFCP PHASE1:Hg19::chr1:19811132..19811155,-#_a28ae4e59a5462693944c19aef901a44p20@CAPZB
2.09e-27FFCP PHASE2:Hg19::chr8:25337491..25337504,+#_7f661acc43092c890ad1f36df6f860bap@chr8:25337491..25337504, +
2.09e-27FFCP PHASE1:Hg19::chr8:25337491..25337504,+#_7f661acc43092c890ad1f36df6f860bap@chr8:25337491..25337504, +
3.59e-26FFCP PHASE2:Hg19::chr2:241897363..241897398,+#_11783b169cda9bf903428f2eefa3b36fp@chr2:241897363..241897398, +
3.59e-26FFCP PHASE1:Hg19::chr2:241897363..241897398,+#_11783b169cda9bf903428f2eefa3b36fp@chr2:241897363..241897398, +
3.89e-25FFCP PHASE2:Hg19::chr6:158490457..158490470,+#_42c62956b9455394d9671fa85390e0f5p10@SYNJ2
3.89e-25FFCP PHASE1:Hg19::chr6:158490457..158490470,+#_42c62956b9455394d9671fa85390e0f5p10@SYNJ2
5.58e-25FFCP PHASE2:Hg19::chr7:18832801..18832816,+#_1003359c34b5418d0aaaf52c09e287ebp21@HDAC9
5.58e-25FFCP PHASE1:Hg19::chr7:18832801..18832816,+#_1003359c34b5418d0aaaf52c09e287ebp21@HDAC9
1.02e-24FFCP PHASE2:Hg19::chr9:16138889..16138902,-#_a6bdf3d03285beccbce8b60839550d55p@chr9:16138889..16138902, -
1.02e-24FFCP PHASE1:Hg19::chr9:16138889..16138902,-#_a6bdf3d03285beccbce8b60839550d55p@chr9:16138889..16138902, -
1.45e-24FFCP PHASE2:Hg19::chr2:241938405..241938416,+#_3f3e66b8b46a299f41cd564e028c5629p@chr2:241938405..241938416, +
1.45e-24FFCP PHASE1:Hg19::chr2:241938405..241938416,+#_3f3e66b8b46a299f41cd564e028c5629p@chr2:241938405..241938416, +
2.34e-24FFCP PHASE1:Hg19::chr8:78311303..78311320,+#_292e669399b41c072cf1dbcd3dd6f914p2@ENST00000518706
2.34e-24FFCP PHASE2:Hg19::chr8:78311303..78311320,+#_292e669399b41c072cf1dbcd3dd6f914p2@ENST00000518706
6.77e-24FFCP PHASE2:Hg19::chr21:39705383..39705394,-#_d2c8e76c8f351de9ff8c9c438a2d5c46p1@ENST00000436845
6.77e-24FFCP PHASE1:Hg19::chr21:39705383..39705394,-#_d2c8e76c8f351de9ff8c9c438a2d5c46p1@ENST00000436845
8.02e-24FFCP PHASE2:Hg19::chr17:38655950..38655954,+#_27f5875d3dcd9ad79692dd238aa7fe8ep@chr17:38655950..38655954, +
8.02e-24FFCP PHASE1:Hg19::chr17:38655950..38655954,+#_27f5875d3dcd9ad79692dd238aa7fe8ep@chr17:38655950..38655954, +
1.13e-23FFCP PHASE2:Hg19::chr14:61190754..61190776,-#_8dc8890acb2cd3f0923ba4a65438ae28p6@SIX4
1.13e-23FFCP PHASE1:Hg19::chr14:61190754..61190776,-#_8dc8890acb2cd3f0923ba4a65438ae28p6@SIX4
1.78e-23FFCP PHASE2:Hg19::chr1:78695298..78695311,+#_aa28eae7bb7da071ef74fd228616de4fp1@ENST00000413519
1.78e-23FFCP PHASE1:Hg19::chr1:78695298..78695311,+#_aa28eae7bb7da071ef74fd228616de4fp1@ENST00000413519
1.14e-21FFCP PHASE2:Hg19::chr11:60610073..60610090,+#_3cbb9c10b8a312c2e1934094aded9e51p6@CCDC86
1.14e-21FFCP PHASE1:Hg19::chr11:60610073..60610090,+#_3cbb9c10b8a312c2e1934094aded9e51p6@CCDC86
1.53e-21FFCP PHASE2:Hg19::chr7:18832913..18832946,+#_93a1b883ca187e79b06e3dfaea5bb004p19@HDAC9
1.53e-21FFCP PHASE1:Hg19::chr7:18832913..18832946,+#_93a1b883ca187e79b06e3dfaea5bb004p19@HDAC9
3.47e-21FFCP PHASE2:Hg19::chr20:30181389..30181408,+#_d0d6628686a8106b9dc327bf14b10506p@chr20:30181389..30181408, +
3.47e-21FFCP PHASE1:Hg19::chr20:30181389..30181408,+#_d0d6628686a8106b9dc327bf14b10506p@chr20:30181389..30181408, +
3.81e-21FFCP PHASE2:Hg19::chr3:158384350..158384362,-#_6ccb323265cb9aee7c0b2ec5f2cddcf1p@chr3:158384350..158384362, -
3.81e-21FFCP PHASE1:Hg19::chr3:158384350..158384362,-#_6ccb323265cb9aee7c0b2ec5f2cddcf1p@chr3:158384350..158384362, -
4.66e-21FFCP PHASE2:Hg19::chr18:12012068..12012098,+#_b54d694840ab16ad9497605a3aff1455p@chr18:12012068..12012098, +
4.66e-21FFCP PHASE1:Hg19::chr18:12012068..12012098,+#_b54d694840ab16ad9497605a3aff1455p@chr18:12012068..12012098, +
5.2e-21FFCP PHASE2:Hg19::chr7:158224707..158224729,-#_5bee2e52d26e18d081acca2e8ab9b019p@chr7:158224707..158224729, -
5.2e-21FFCP PHASE1:Hg19::chr7:158224707..158224729,-#_5bee2e52d26e18d081acca2e8ab9b019p@chr7:158224707..158224729, -
6.96e-21FFCP PHASE2:Hg19::chr2:158345440..158345449,-#_3361c9162cdfbd224df5f605d6414b8bp9@CYTIP
6.96e-21FFCP PHASE1:Hg19::chr2:158345440..158345449,-#_3361c9162cdfbd224df5f605d6414b8bp9@CYTIP
6.96e-21FFCP PHASE2:Hg19::chr11:108743668..108743675,+#_3361c9162cdfbd224df5f605d6414b8bp@chr11:108743668..108743675, +
6.96e-21FFCP PHASE1:Hg19::chr11:108743668..108743675,+#_3361c9162cdfbd224df5f605d6414b8bp@chr11:108743668..108743675, +
8.49e-21FFCP PHASE1:Hg19::chr6:158490395..158490407,+#_ca84713ff7c4466f979fa58ed7df3f54p9@SYNJ2
8.49e-21FFCP PHASE2:Hg19::chr6:158490395..158490407,+#_ca84713ff7c4466f979fa58ed7df3f54p9@SYNJ2
2.74e-20FFCP PHASE1:Hg19::chr1:65888177..65888194,+#_fcabdf4cf9557716bfcc8d1df1d9ba7cp@chr1:65888177..65888194, +
2.74e-20FFCP PHASE2:Hg19::chr1:65888177..65888194,+#_fcabdf4cf9557716bfcc8d1df1d9ba7cp@chr1:65888177..65888194, +
1.64e-19FFCP PHASE2:Hg19::chr19:14223369..14223385,-#_242b3145e30869fe254c85fdc8325864p5@PRKACA
1.64e-19FFCP PHASE1:Hg19::chr19:14223369..14223385,-#_242b3145e30869fe254c85fdc8325864p5@PRKACA
2.38e-19FFCP PHASE2:Hg19::chr9:113798560..113798572,-#_714e81ec7f1b26e825d5cbc1a1523f73p34@LPAR1
2.38e-19FFCP PHASE1:Hg19::chr9:113798560..113798572,-#_714e81ec7f1b26e825d5cbc1a1523f73p34@LPAR1
4.53e-19FFCP PHASE1:Hg19::chr17:73688878..73688882,+#_876e2039ebbb8247e69f79ea20f8dec7p@chr17:73688878..73688882, +
4.53e-19FFCP PHASE2:Hg19::chr17:73688878..73688882,+#_876e2039ebbb8247e69f79ea20f8dec7p@chr17:73688878..73688882, +
6.53e-19FFCP PHASE2:Hg19::chr3:58572689..58572703,-#_77402ce541fe4f078c2c8cfbf82dfe8fp6@FAM107A
6.53e-19FFCP PHASE1:Hg19::chr3:58572689..58572703,-#_77402ce541fe4f078c2c8cfbf82dfe8fp6@FAM107A
7.03e-19FFCP PHASE2:Hg19::chr1:78695274..78695292,+#_13f58d9228aca027decb6226093a849ap1@MGC27382
7.03e-19FFCP PHASE1:Hg19::chr1:78695274..78695292,+#_13f58d9228aca027decb6226093a849ap1@MGC27382