FANTOM

FANTOM is an international research consortium established by Dr. Hayashizaki and his colleagues in 2000 to assign functional annotations to the full-length cDNAs that were collected during the Mouse Encyclopedia Project at RIKEN. FANTOM has since developed and expanded over time to encompass the fields of transcriptome analysis. The object of the project is moving steadily up the layers in the system of life, progressing thus from an understanding of the ‘elements’ - the transcripts - to an understanding of the ‘system’ - the transcriptional regulatory network, in other words the ‘system’ of an individual life form.

Mouse over the image below for information on FANTOM history and publications. FANTOM history FANTOM4 Main Paper FANTOM4 Satellite Paper FANTOM4 Main Paper FANTOM3 Satellite Paper FANTOM3 Main Paper FANTOM3 Main Paper FANTOM2 Satellite Paper FANTOM2 Main Paper FANTOM1 Main Paper FANTOM5 FANTOM4 FANTOM3 FANTOM2 FANTOM1 October 2011 - FANTOM5 meeting December 2006 - FANTOM4 meeting September 2004 - FANTOM3 main meeting April 2002 - FANTOM2 meeting August/September 2000 - FANTOM1 meeting

Simultaneously with producing data, FANTOM established the FANTOM database and the FANTOM full-length cDNA clone bank, which are available worldwide. The FANTOM resources have been used in several important research projects. For instance, the full-length cDNA database was used in a computer prediction of the genomic position (transcriptional unit) of genes by the International Human Genome Sequencing Consortium. Also they have been used by a research group led by Dr. Shinya Yamanaka at Kyoto University, Japan, for establishing Induced pluripotent stem (iPS) cells. In the study, 24 transcription factors were selected from FANTOM database as candidate initiation factors. Furthermore, the Allen Institute for Brain Science in the United State has created a digital atlas that encompasses the whole brain, and has made it publicly available. The atlas graphically illustrates the expression of genes within the mouse brain using Informatix software. This project has also made use of the FANTOM database.