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Novel motif:100

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name:motif100_GCYTNCTC

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0032863 activation of Rac GTPase activity 8.296925e-8
GO:0032862 activation of Rho GTPase activity 9.997133e-8
GO:0060216 definitive hemopoiesis 1.526459e-7
GO:0014812 muscle cell migration 2.568649e-7
GO:0018277 protein deamination 4.036051e-7
GO:0060977 coronary vasculature morphogenesis 6.060410e-7
GO:0032911 negative regulation of transforming growth factor beta1 production 9.314494e-7
GO:0043586 tongue development 1.195738e-6
GO:2000251 positive regulation of actin cytoskeleton reorganization 1.234662e-6
GO:0071934 thiamine transmembrane transport 1.378612e-6
GO:0033693 neurofilament bundle assembly 1.468194e-6
GO:0060215 primitive hemopoiesis 2.388512e-6
GO:0045109 intermediate filament organization 2.860447e-6
GO:0016241 regulation of macroautophagy 3.498727e-6
GO:0035023 regulation of Rho protein signal transduction 4.675129e-6
GO:0014909 smooth muscle cell migration 4.806595e-6
GO:0032902 nerve growth factor production 5.499771e-6
GO:0051546 keratinocyte migration 6.546410e-6
GO:0007422 peripheral nervous system development 8.714653e-6
GO:0043585 nose morphogenesis 9.023183e-6
GO:0046847 filopodium assembly 9.241085e-6
GO:0030224 monocyte differentiation 1.100784e-5
GO:0046578 regulation of Ras protein signal transduction 1.187586e-5
GO:0071529 cementum mineralization 1.233623e-5
GO:0043353 enucleate erythrocyte differentiation 1.265344e-5
GO:0060976 coronary vasculature development 1.388492e-5
GO:0072676 lymphocyte migration 1.426549e-5
GO:0071105 response to interleukin-11 1.551061e-5
GO:0035419 activation of MAPK activity involved in innate immune response 2.042465e-5
GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation 2.073913e-5
GO:2000467 positive regulation of glycogen (starch) synthase activity 2.264107e-5
GO:0032042 mitochondrial DNA metabolic process 3.071890e-5
GO:0090183 regulation of kidney development 3.149945e-5
GO:0045110 intermediate filament bundle assembly 3.386358e-5
GO:0030035 microspike assembly 4.427496e-5
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 4.493942e-5
GO:2000249 regulation of actin cytoskeleton reorganization 4.686483e-5
GO:0060443 mammary gland morphogenesis 5.250634e-5
GO:0008628 induction of apoptosis by hormones 5.592728e-5
GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 5.671412e-5
GO:0032012 regulation of ARF protein signal transduction 5.712129e-5
GO:0051495 positive regulation of cytoskeleton organization 5.910637e-5
GO:0070294 renal sodium ion absorption 5.934515e-5
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 6.523569e-5
GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process 6.526286e-5
GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process 6.688834e-5
GO:0010452 histone H3-K36 methylation 7.554594e-5
GO:0031129 inductive cell-cell signaling 7.736739e-5
GO:0001575 globoside metabolic process 7.817089e-5
GO:0035752 lysosomal lumen pH elevation 7.817089e-5
GO:0000046 autophagic vacuole fusion 7.817089e-5
GO:0035441 cell migration involved in vasculogenesis 7.999657e-5
GO:0006702 androgen biosynthetic process 8.230253e-5
GO:0044340 canonical Wnt receptor signaling pathway involved in regulation of cell proliferation 8.580593e-5
GO:0060525 prostate glandular acinus development 9.047154e-5
GO:0018272 protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine 9.589169e-5
GO:0032312 regulation of ARF GTPase activity 9.666647e-5
GO:0071392 cellular response to estradiol stimulus 9.686144e-5
GO:0031017 exocrine pancreas development 1.046556e-4
GO:0045943 positive regulation of transcription from RNA polymerase I promoter 1.200490e-4
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 1.270572e-4
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 1.270572e-4
GO:0032455 nerve growth factor processing 1.303535e-4
GO:0061143 alveolar primary septum development 1.344744e-4
GO:0007296 vitellogenesis 1.396197e-4
GO:0060426 lung vasculature development 1.455041e-4
GO:0050872 white fat cell differentiation 1.494568e-4
GO:0043587 tongue morphogenesis 1.530556e-4
GO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathway 1.556912e-4
GO:0045945 positive regulation of transcription from RNA polymerase III promoter 1.593355e-4
GO:0030879 mammary gland development 1.600995e-4
GO:0009584 detection of visible light 1.617811e-4
GO:0002230 positive regulation of defense response to virus by host 1.629301e-4
GO:0046831 regulation of RNA export from nucleus 1.675596e-4
GO:0022011 myelination in peripheral nervous system 1.744304e-4
GO:0030834 regulation of actin filament depolymerization 1.793091e-4
GO:0014037 Schwann cell differentiation 1.800997e-4
GO:0010801 negative regulation of peptidyl-threonine phosphorylation 1.878955e-4
GO:0071243 cellular response to arsenic-containing substance 1.894937e-4
GO:0060765 regulation of androgen receptor signaling pathway 1.930998e-4
GO:0051298 centrosome duplication 2.063494e-4
GO:0003096 renal sodium ion transport 2.248558e-4
GO:0032856 activation of Ras GTPase activity 2.254296e-4
GO:0002067 glandular epithelial cell differentiation 2.264343e-4
GO:0007131 reciprocal meiotic recombination 2.365138e-4
GO:0060444 branching involved in mammary gland duct morphogenesis 2.508993e-4
GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning 2.549768e-4
GO:0002031 G-protein coupled receptor internalization 2.588634e-4
GO:0060052 neurofilament cytoskeleton organization 2.617016e-4
GO:0014044 Schwann cell development 2.624571e-4
GO:0060766 negative regulation of androgen receptor signaling pathway 2.722397e-4
GO:0042733 embryonic digit morphogenesis 3.046770e-4
GO:0001702 gastrulation with mouth forming second 3.352855e-4
GO:0035914 skeletal muscle cell differentiation 3.712320e-4
GO:0019934 cGMP-mediated signaling 3.753341e-4
GO:2000110 negative regulation of macrophage apoptosis 3.758765e-4
GO:2000363 positive regulation of prostaglandin-E synthase activity 3.758765e-4
GO:0071608 macrophage inflammatory protein-1 alpha production 3.758765e-4
GO:0032498 detection of muramyl dipeptide 3.758765e-4
GO:0006965 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria 3.758765e-4
GO:0032701 negative regulation of interleukin-18 production 3.758765e-4
GO:0060687 regulation of branching involved in prostate gland morphogenesis 3.886414e-4
GO:0014902 myotube differentiation 3.892888e-4
GO:0048168 regulation of neuronal synaptic plasticity 3.994393e-4
GO:2000465 regulation of glycogen (starch) synthase activity 4.270242e-4
GO:0031334 positive regulation of protein complex assembly 4.296944e-4
GO:0014908 myotube differentiation involved in skeletal muscle regeneration 4.351470e-4
GO:0080009 mRNA methylation 4.351470e-4
GO:0090031 positive regulation of steroid hormone biosynthetic process 4.520158e-4
GO:0060711 labyrinthine layer development 4.670877e-4
GO:0043542 endothelial cell migration 4.705423e-4
GO:0071593 lymphocyte aggregation 4.729632e-4
GO:0016242 negative regulation of macroautophagy 4.743108e-4
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 4.846883e-4
GO:0070670 response to interleukin-4 4.957937e-4
GO:2001054 negative regulation of mesenchymal cell apoptosis 5.014958e-4
GO:0001812 positive regulation of type I hypersensitivity 5.014958e-4
GO:0002065 columnar/cuboidal epithelial cell differentiation 5.075831e-4
GO:0042274 ribosomal small subunit biogenesis 5.076928e-4
GO:0045824 negative regulation of innate immune response 5.140629e-4
GO:0060713 labyrinthine layer morphogenesis 5.183331e-4
GO:0001955 blood vessel maturation 5.542711e-4
GO:0008624 induction of apoptosis by extracellular signals 5.568986e-4
GO:0008089 anterograde axon cargo transport 5.594100e-4
GO:0032956 regulation of actin cytoskeleton organization 5.839093e-4
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 5.893853e-4
GO:0045061 thymic T cell selection 6.052256e-4
GO:0043084 penile erection 6.093629e-4
GO:0071635 negative regulation of transforming growth factor beta production 6.130906e-4
GO:0060674 placenta blood vessel development 6.171683e-4
GO:0003279 cardiac septum development 6.271784e-4
GO:0050764 regulation of phagocytosis 6.571830e-4
GO:0032796 uropod organization 6.590329e-4
GO:0045332 phospholipid translocation 6.675854e-4
GO:0007028 cytoplasm organization 6.710224e-4
GO:0051450 myoblast proliferation 6.717464e-4
GO:0060742 epithelial cell differentiation involved in prostate gland development 6.885882e-4
GO:0071670 smooth muscle cell chemotaxis 7.068424e-4
GO:0060981 cell migration involved in coronary angiogenesis 7.068424e-4
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 7.215283e-4
GO:0042552 myelination 7.615371e-4
GO:0060997 dendritic spine morphogenesis 7.620918e-4
GO:0035357 peroxisome proliferator activated receptor signaling pathway 7.815496e-4
GO:0019067 viral assembly, maturation, egress, and release 7.831315e-4
GO:0035136 forelimb morphogenesis 8.019590e-4
GO:0061034 olfactory bulb mitral cell layer development 8.040388e-4
GO:0045163 clustering of voltage-gated potassium channels 8.040388e-4
GO:0042473 outer ear morphogenesis 8.272932e-4
GO:0060603 mammary gland duct morphogenesis 8.709950e-4
GO:0030853 negative regulation of granulocyte differentiation 8.743119e-4
GO:0050775 positive regulation of dendrite morphogenesis 8.828766e-4
GO:0001826 inner cell mass cell differentiation 8.847553e-4
GO:0006264 mitochondrial DNA replication 9.159818e-4
GO:0002698 negative regulation of immune effector process 9.274194e-4
GO:0072107 positive regulation of ureteric bud formation 9.374516e-4
GO:0071104 response to interleukin-9 9.691060e-4
GO:0048246 macrophage chemotaxis 9.733131e-4
GO:0000379 tRNA-type intron splice site recognition and cleavage 1.029175e-3
GO:0045200 establishment of neuroblast polarity 1.029175e-3
GO:0006898 receptor-mediated endocytosis 1.066056e-3
GO:0043244 regulation of protein complex disassembly 1.068465e-3
GO:0044330 canonical Wnt receptor signaling pathway involved in positive regulation of wound healing 1.105530e-3
GO:0044329 canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion 1.105530e-3
GO:0044328 canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration 1.105530e-3
GO:2000786 positive regulation of autophagic vacuole assembly 1.141398e-3
GO:0007098 centrosome cycle 1.145650e-3
GO:0090030 regulation of steroid hormone biosynthetic process 1.165146e-3
GO:0043088 regulation of Cdc42 GTPase activity 1.178410e-3
GO:0070858 negative regulation of bile acid biosynthetic process 1.197747e-3
GO:0021644 vagus nerve morphogenesis 1.231718e-3
GO:0002017 regulation of blood volume by renal aldosterone 1.233096e-3
GO:0046502 uroporphyrinogen III metabolic process 1.245239e-3
GO:0048755 branching morphogenesis of a nerve 1.246870e-3
GO:0045191 regulation of isotype switching 1.285783e-3
GO:0060973 cell migration involved in heart development 1.312527e-3
GO:0042723 thiamine-containing compound metabolic process 1.329036e-3
GO:0033158 regulation of protein import into nucleus, translocation 1.337246e-3
GO:0019367 fatty acid elongation, saturated fatty acid 1.367602e-3
GO:0060056 mammary gland involution 1.369548e-3
GO:0008064 regulation of actin polymerization or depolymerization 1.403296e-3
GO:0006797 polyphosphate metabolic process 1.435285e-3
GO:0043314 negative regulation of neutrophil degranulation 1.437424e-3
GO:0048013 ephrin receptor signaling pathway 1.440449e-3
GO:0007127 meiosis I 1.466346e-3
GO:0048808 male genitalia morphogenesis 1.471938e-3
GO:0046426 negative regulation of JAK-STAT cascade 1.473715e-3
GO:0003281 ventricular septum development 1.582211e-3
GO:0019370 leukotriene biosynthetic process 1.604153e-3
GO:0016556 mRNA modification 1.622617e-3
GO:0032275 luteinizing hormone secretion 1.641675e-3
GO:0046884 follicle-stimulating hormone secretion 1.641675e-3
GO:0018352 protein-pyridoxal-5-phosphate linkage 1.641675e-3
GO:0000416 positive regulation of histone H3-K36 methylation 1.641675e-3
GO:0060263 regulation of respiratory burst 1.654571e-3
GO:0046628 positive regulation of insulin receptor signaling pathway 1.678733e-3
GO:0015809 arginine transport 1.702837e-3
GO:0046732 active induction of host immune response by virus 1.702837e-3
GO:0032970 regulation of actin filament-based process 1.746320e-3
GO:0001732 formation of translation initiation complex 1.771531e-3
GO:0030827 negative regulation of cGMP biosynthetic process 1.785840e-3
GO:0035129 post-embryonic hindlimb morphogenesis 1.785840e-3
GO:0016575 histone deacetylation 1.810372e-3
GO:0051454 intracellular pH elevation 1.811447e-3
GO:0043648 dicarboxylic acid metabolic process 1.874065e-3
GO:0032780 negative regulation of ATPase activity 1.877481e-3
GO:0046340 diacylglycerol catabolic process 1.889590e-3
GO:0045649 regulation of macrophage differentiation 1.893423e-3
GO:0030836 positive regulation of actin filament depolymerization 1.908895e-3
GO:0048286 lung alveolus development 1.920022e-3
GO:0097152 mesenchymal cell apoptosis 1.967065e-3
GO:2001037 positive regulation of tongue muscle cell differentiation 1.967065e-3
GO:0060982 coronary artery morphogenesis 1.967065e-3
GO:0070489 T cell aggregation 1.975321e-3
GO:0060219 camera-type eye photoreceptor cell differentiation 1.994802e-3
GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein 1.996026e-3
GO:0032497 detection of lipopolysaccharide 1.996026e-3
GO:0043583 ear development 1.999117e-3
GO:0010638 positive regulation of organelle organization 2.013295e-3
GO:0071168 protein localization to chromatin 2.037071e-3
GO:0032239 regulation of nucleobase-containing compound transport 2.037071e-3
GO:0006435 threonyl-tRNA aminoacylation 2.037071e-3
GO:0002091 negative regulation of receptor internalization 2.037071e-3
GO:0061198 fungiform papilla formation 2.056361e-3
GO:0051573 negative regulation of histone H3-K9 methylation 2.076671e-3
GO:0019344 cysteine biosynthetic process 2.105524e-3
GO:0032912 negative regulation of transforming growth factor beta2 production 2.105524e-3
GO:0060022 hard palate development 2.106158e-3
GO:0046784 intronless viral mRNA export from host nucleus 2.106158e-3
GO:0009215 purine deoxyribonucleoside triphosphate metabolic process 2.135892e-3
GO:0051056 regulation of small GTPase mediated signal transduction 2.143986e-3
GO:0010225 response to UV-C 2.202047e-3
GO:0001768 establishment of T cell polarity 2.202047e-3
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 2.221549e-3
GO:0048266 behavioral response to pain 2.271198e-3
GO:0051645 Golgi localization 2.277837e-3
GO:0043519 regulation of myosin II filament organization 2.277837e-3
GO:0010543 regulation of platelet activation 2.296890e-3
GO:0097035 regulation of membrane lipid distribution 2.343288e-3
GO:0060363 cranial suture morphogenesis 2.353920e-3
GO:0002740 negative regulation of cytokine secretion involved in immune response 2.385235e-3
GO:0001835 blastocyst hatching 2.399047e-3
GO:0045650 negative regulation of macrophage differentiation 2.471015e-3
GO:0007386 compartment pattern specification 2.472257e-3
GO:0034109 homotypic cell-cell adhesion 2.493705e-3
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 2.507916e-3
GO:0045059 positive thymic T cell selection 2.536232e-3
GO:0034389 lipid particle organization 2.572877e-3
GO:0031503 protein complex localization 2.599163e-3
GO:0033089 positive regulation of T cell differentiation in thymus 2.611337e-3
GO:0060364 frontal suture morphogenesis 2.622472e-3
GO:0032534 regulation of microvillus assembly 2.635559e-3
GO:0043932 ossification involved in bone remodeling 2.642174e-3
GO:0060453 regulation of gastric acid secretion 2.696850e-3
GO:0048102 autophagic cell death 2.771980e-3
GO:0032790 ribosome disassembly 2.785979e-3
GO:0006529 asparagine biosynthetic process 2.881498e-3
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 2.881498e-3
GO:0033160 positive regulation of protein import into nucleus, translocation 2.979471e-3
GO:0090086 negative regulation of protein deubiquitination 2.987457e-3
GO:0007518 myoblast cell fate determination 2.987457e-3
GO:0070814 hydrogen sulfide biosynthetic process 2.987457e-3
GO:2000053 regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 2.989547e-3
GO:0035455 response to interferon-alpha 3.011289e-3
GO:0030183 B cell differentiation 3.028877e-3
GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling 3.031463e-3
GO:0010893 positive regulation of steroid biosynthetic process 3.100612e-3
GO:0006984 ER-nucleus signaling pathway 3.141311e-3
GO:2000162 negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis 3.149850e-3
GO:2000166 negative regulation of planar cell polarity pathway involved in pericardium morphogenesis 3.149850e-3
GO:2000168 negative regulation of planar cell polarity pathway involved in neural tube closure 3.149850e-3
GO:2000151 negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 3.149850e-3
GO:2000164 negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis 3.149850e-3
GO:0061310 canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development 3.149850e-3
GO:2000055 positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 3.149850e-3
GO:0002071 glandular epithelial cell maturation 3.149850e-3
GO:2000149 negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis 3.149850e-3
GO:0043300 regulation of leukocyte degranulation 3.296080e-3
GO:0010721 negative regulation of cell development 3.302531e-3
GO:0032727 positive regulation of interferon-alpha production 3.316037e-3
GO:0000712 resolution of meiotic recombination intermediates 3.337463e-3
GO:0007341 penetration of zona pellucida 3.375201e-3
GO:0002862 negative regulation of inflammatory response to antigenic stimulus 3.375201e-3
GO:0034505 tooth mineralization 3.416037e-3
GO:0035117 embryonic arm morphogenesis 3.424099e-3
GO:0014014 negative regulation of gliogenesis 3.445610e-3
GO:0031929 TOR signaling cascade 3.457280e-3
GO:0061324 canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation 3.472525e-3
GO:0019896 axon transport of mitochondrion 3.522257e-3
GO:0090042 tubulin deacetylation 3.554101e-3
GO:0070846 Hsp90 deacetylation 3.554101e-3
GO:0060209 estrus 3.554101e-3
GO:0070407 oxidation-dependent protein catabolic process 3.554101e-3
GO:0070831 basement membrane assembly 3.554101e-3
GO:0022617 extracellular matrix disassembly 3.608295e-3
GO:0008366 axon ensheathment 3.627939e-3
GO:0007172 signal complex assembly 3.654286e-3
GO:0032226 positive regulation of synaptic transmission, dopaminergic 3.916675e-3
GO:0006554 lysine catabolic process 3.952305e-3
GO:0051764 actin crosslink formation 3.967715e-3
GO:0018023 peptidyl-lysine trimethylation 3.981178e-3
GO:0072215 regulation of metanephros development 4.025329e-3
GO:0051323 metaphase 4.232677e-3
GO:0010799 regulation of peptidyl-threonine phosphorylation 4.240705e-3
GO:0031063 regulation of histone deacetylation 4.257596e-3
GO:0060555 induction of necroptosis by extracellular signals 4.287106e-3
GO:0071897 DNA biosynthetic process 4.302448e-3
GO:0042593 glucose homeostasis 4.324275e-3
GO:0009200 deoxyribonucleoside triphosphate metabolic process 4.344819e-3
GO:0060021 palate development 4.355184e-3
GO:0070816 phosphorylation of RNA polymerase II C-terminal domain 4.381230e-3
GO:0032287 peripheral nervous system myelin maintenance 4.381230e-3
GO:0046006 regulation of activated T cell proliferation 4.431735e-3
GO:0070127 tRNA aminoacylation for mitochondrial protein translation 4.433511e-3
GO:0061196 fungiform papilla development 4.455313e-3
GO:0043313 regulation of neutrophil degranulation 4.455313e-3
GO:0021940 positive regulation of cerebellar granule cell precursor proliferation 4.485757e-3
GO:0051295 establishment of meiotic spindle localization 4.485757e-3
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 4.515656e-3
GO:0031297 replication fork processing 4.563968e-3
GO:0010616 negative regulation of cardiac muscle adaptation 4.594515e-3
GO:0021943 formation of radial glial scaffolds 4.598369e-3
GO:0032855 positive regulation of Rac GTPase activity 4.763336e-3
GO:0000018 regulation of DNA recombination 4.800767e-3
GO:0030490 maturation of SSU-rRNA 4.929114e-3
GO:0048568 embryonic organ development 4.935288e-3
GO:0061180 mammary gland epithelium development 4.963017e-3
GO:0030098 lymphocyte differentiation 4.992223e-3
GO:0060520 activation of prostate induction by androgen receptor signaling pathway 5.013642e-3
GO:0045720 negative regulation of integrin biosynthetic process 5.013642e-3
GO:0019102 male somatic sex determination 5.013642e-3
GO:0035048 splicing factor protein import into nucleus 5.067088e-3
GO:0007569 cell aging 5.072031e-3
GO:0021874 Wnt receptor signaling pathway involved in forebrain neuroblast division 5.158302e-3
GO:0090245 axis elongation involved in somitogenesis 5.158302e-3
GO:0001808 negative regulation of type IV hypersensitivity 5.158302e-3
GO:0051152 positive regulation of smooth muscle cell differentiation 5.194428e-3
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 5.214010e-3
GO:0050902 leukocyte adhesive activation 5.214010e-3
GO:0008049 male courtship behavior 5.300634e-3
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 5.300634e-3
GO:0006781 succinyl-CoA pathway 5.300634e-3
GO:0015914 phospholipid transport 5.345960e-3
GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine 5.378196e-3
GO:0006939 smooth muscle contraction 5.438600e-3
GO:0050766 positive regulation of phagocytosis 5.453435e-3
GO:0014013 regulation of gliogenesis 5.534447e-3
GO:0030208 dermatan sulfate biosynthetic process 5.608670e-3
GO:0010034 response to acetate 5.608670e-3
GO:0060688 regulation of morphogenesis of a branching structure 5.662121e-3
GO:0045347 negative regulation of MHC class II biosynthetic process 5.704703e-3
GO:0030838 positive regulation of actin filament polymerization 5.708372e-3
GO:0048167 regulation of synaptic plasticity 5.764373e-3
GO:0048562 embryonic organ morphogenesis 5.910268e-3
GO:0016539 intein-mediated protein splicing 5.944496e-3
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.997475e-3
GO:0032273 positive regulation of protein polymerization 6.082772e-3
GO:0006476 protein deacetylation 6.098224e-3
GO:0010719 negative regulation of epithelial to mesenchymal transition 6.114524e-3
GO:0061048 negative regulation of branching involved in lung morphogenesis 6.249791e-3
GO:0035247 peptidyl-arginine omega-N-methylation 6.347495e-3
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 6.437780e-3
GO:0030835 negative regulation of actin filament depolymerization 6.459693e-3
GO:0001921 positive regulation of receptor recycling 6.532723e-3
GO:0045104 intermediate filament cytoskeleton organization 6.667534e-3
GO:0002521 leukocyte differentiation 6.685253e-3
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 6.702392e-3
GO:0006704 glucocorticoid biosynthetic process 6.781444e-3
GO:0060596 mammary placode formation 6.843295e-3
GO:0001570 vasculogenesis 6.926095e-3
GO:0060439 trachea morphogenesis 6.951223e-3
GO:0010592 positive regulation of lamellipodium assembly 6.964049e-3
GO:0046639 negative regulation of alpha-beta T cell differentiation 7.005281e-3
GO:0043476 pigment accumulation 7.113071e-3
GO:0043482 cellular pigment accumulation 7.113071e-3
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process 7.113071e-3
GO:0035601 protein deacylation 7.223846e-3
GO:0060628 regulation of ER to Golgi vesicle-mediated transport 7.341491e-3
GO:0045608 negative regulation of auditory receptor cell differentiation 7.362586e-3
GO:0071407 cellular response to organic cyclic compound 7.410038e-3
GO:0060816 random inactivation of X chromosome 7.460812e-3
GO:0060840 artery development 7.501974e-3
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 7.516533e-3
GO:0044088 regulation of vacuole organization 7.516533e-3
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 7.516533e-3
GO:0001805 positive regulation of type III hypersensitivity 7.516533e-3
GO:0002431 Fc receptor mediated stimulatory signaling pathway 7.516533e-3
GO:0016046 detection of fungus 7.516533e-3
GO:0046415 urate metabolic process 7.575000e-3
GO:0021861 forebrain radial glial cell differentiation 7.579859e-3
GO:0045112 integrin biosynthetic process 7.649638e-3
GO:0070845 polyubiquitinated misfolded protein transport 7.693204e-3
GO:0002537 nitric oxide production involved in inflammatory response 7.693204e-3
GO:0046070 dGTP metabolic process 7.779680e-3
GO:0051293 establishment of spindle localization 7.811985e-3
GO:0048255 mRNA stabilization 7.811985e-3
GO:0046532 regulation of photoreceptor cell differentiation 7.823724e-3
GO:0043461 proton-transporting ATP synthase complex assembly 7.861570e-3
GO:0048247 lymphocyte chemotaxis 7.867245e-3
GO:0006691 leukotriene metabolic process 7.936900e-3
GO:0030917 midbrain-hindbrain boundary development 7.947844e-3
GO:0048561 establishment of organ orientation 8.030415e-3
GO:0048178 negative regulation of hepatocyte growth factor biosynthetic process 8.030415e-3
GO:0044335 canonical Wnt receptor signaling pathway involved in neural crest cell differentiation 8.030415e-3
GO:0001807 regulation of type IV hypersensitivity 8.030415e-3
GO:0070979 protein K11-linked ubiquitination 8.045055e-3
GO:0016191 synaptic vesicle uncoating 8.197826e-3
GO:0010793 regulation of mRNA export from nucleus 8.197826e-3
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.197826e-3
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.197826e-3
GO:0002149 hypochlorous acid biosynthetic process 8.269840e-3
GO:0042998 positive regulation of Golgi to plasma membrane protein transport 8.322730e-3
GO:0032490 detection of molecule of bacterial origin 8.408474e-3
GO:0035115 embryonic forelimb morphogenesis 8.486296e-3
GO:0010511 regulation of phosphatidylinositol biosynthetic process 8.702225e-3
GO:0061205 paramesonephric duct development 8.847935e-3
GO:0060947 cardiac vascular smooth muscle cell differentiation 8.847935e-3
GO:0032765 positive regulation of mast cell cytokine production 8.847935e-3
GO:0051224 negative regulation of protein transport 8.855636e-3
GO:0007603 phototransduction, visible light 8.895246e-3
GO:0046902 regulation of mitochondrial membrane permeability 8.915686e-3
GO:0048012 hepatocyte growth factor receptor signaling pathway 9.072272e-3
GO:0072110 glomerular mesangial cell proliferation 9.079976e-3
GO:0032530 regulation of microvillus organization 9.079976e-3
GO:0045085 negative regulation of interleukin-2 biosynthetic process 9.079976e-3
GO:0010310 regulation of hydrogen peroxide metabolic process 9.143088e-3
GO:0042088 T-helper 1 type immune response 9.301261e-3
GO:0032964 collagen biosynthetic process 9.303569e-3
GO:0002883 regulation of hypersensitivity 9.320271e-3
GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development 9.406595e-3
GO:0032233 positive regulation of actin filament bundle assembly 9.485249e-3
GO:0061316 canonical Wnt receptor signaling pathway involved in heart development 9.685734e-3
GO:0001569 patterning of blood vessels 9.759308e-3
GO:0045355 negative regulation of interferon-alpha biosynthetic process 9.768286e-3
GO:0050868 negative regulation of T cell activation 9.971920e-3
GO:0006353 transcription termination, DNA-dependent 1.004308e-2
GO:0032763 regulation of mast cell cytokine production 1.007464e-2
GO:0040040 thermosensory behavior 1.012830e-2
GO:0010159 specification of organ position 1.012830e-2
GO:0072393 microtubule anchoring at microtubule organizing center 1.027430e-2
GO:0035089 establishment of apical/basal cell polarity 1.027430e-2
GO:0010572 positive regulation of platelet activation 1.039889e-2
GO:0007132 meiotic metaphase I 1.044158e-2
GO:0035640 exploration behavior 1.050684e-2
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 1.050997e-2
GO:0010912 positive regulation of isomerase activity 1.056733e-2
GO:0071353 cellular response to interleukin-4 1.057641e-2
GO:0060463 lung lobe morphogenesis 1.057641e-2
GO:0050849 negative regulation of calcium-mediated signaling 1.059595e-2
GO:0090303 positive regulation of wound healing 1.060024e-2
GO:0021932 hindbrain radial glia guided cell migration 1.061862e-2
GO:0060996 dendritic spine development 1.069587e-2
GO:0030901 midbrain development 1.072464e-2
GO:0015893 drug transport 1.084431e-2
GO:0001890 placenta development 1.116499e-2
GO:0000019 regulation of mitotic recombination 1.120217e-2
GO:0046782 regulation of viral transcription 1.121331e-2
GO:0048570 notochord morphogenesis 1.126138e-2
GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development 1.126138e-2
GO:0043534 blood vessel endothelial cell migration 1.133338e-2
GO:0050765 negative regulation of phagocytosis 1.138672e-2
GO:0046885 regulation of hormone biosynthetic process 1.138683e-2
GO:0033092 positive regulation of immature T cell proliferation in thymus 1.152626e-2
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 1.168112e-2
GO:0050883 musculoskeletal movement, spinal reflex action 1.174288e-2
GO:0071423 malate transmembrane transport 1.174288e-2
GO:0015709 thiosulfate transport 1.174288e-2
GO:0008594 photoreceptor cell morphogenesis 1.174288e-2
GO:0060325 face morphogenesis 1.175288e-2
GO:0021936 regulation of cerebellar granule cell precursor proliferation 1.177686e-2
GO:0070483 detection of hypoxia 1.179736e-2
GO:0035461 vitamin transmembrane transport 1.182438e-2
GO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development 1.182438e-2
GO:0060980 cell migration involved in coronary vasculogenesis 1.182438e-2
GO:0090076 relaxation of skeletal muscle 1.197162e-2
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 1.197162e-2
GO:0001309 age-dependent telomere shortening 1.197162e-2
GO:0032214 negative regulation of telomere maintenance via semi-conservative replication 1.197162e-2
GO:0045940 positive regulation of steroid metabolic process 1.197277e-2
GO:0031936 negative regulation of chromatin silencing 1.198772e-2
GO:0072385 minus-end-directed organelle transport along microtubule 1.204769e-2
GO:0060754 positive regulation of mast cell chemotaxis 1.214574e-2
GO:0034969 histone arginine methylation 1.214574e-2
GO:0033121 regulation of purine nucleotide catabolic process 1.215160e-2
GO:0006515 misfolded or incompletely synthesized protein catabolic process 1.220058e-2
GO:0002762 negative regulation of myeloid leukocyte differentiation 1.220440e-2
GO:0070293 renal absorption 1.231993e-2
GO:0060710 chorio-allantoic fusion 1.245657e-2
GO:0021873 forebrain neuroblast division 1.245657e-2
GO:0090311 regulation of protein deacetylation 1.246180e-2
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 1.246601e-2
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 1.258105e-2
GO:0090184 positive regulation of kidney development 1.260097e-2
GO:0055123 digestive system development 1.267873e-2
GO:0071397 cellular response to cholesterol 1.283619e-2
GO:0010756 positive regulation of plasminogen activation 1.292085e-2
GO:0032225 regulation of synaptic transmission, dopaminergic 1.305560e-2
GO:0043508 negative regulation of JUN kinase activity 1.305560e-2
GO:0070857 regulation of bile acid biosynthetic process 1.312149e-2
GO:0021784 postganglionic parasympathetic nervous system development 1.312149e-2
GO:0035137 hindlimb morphogenesis 1.332125e-2


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0016579 protein deubiquitination 4.074329e-10
GO:0090201 negative regulation of release of cytochrome c from mitochondria 8.145906e-9
GO:0043471 regulation of cellular carbohydrate catabolic process 8.628653e-9
GO:0070646 protein modification by small protein removal 1.690285e-8
GO:0045351 type I interferon biosynthetic process 2.548323e-8
GO:0010823 negative regulation of mitochondrion organization 3.019485e-8
GO:0010982 regulation of high-density lipoprotein particle clearance 7.653013e-8
GO:0060923 cardiac muscle cell fate commitment 2.237281e-7
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 2.292509e-7
GO:2000194 regulation of female gonad development 5.412456e-7
GO:0045869 negative regulation of retroviral genome replication 6.256341e-7
GO:0010987 negative regulation of high-density lipoprotein particle clearance 6.578311e-7
GO:0010897 negative regulation of triglyceride catabolic process 6.578311e-7
GO:0006110 regulation of glycolysis 7.648458e-7
GO:0003221 right ventricular cardiac muscle tissue morphogenesis 1.065964e-6
GO:0006297 nucleotide-excision repair, DNA gap filling 1.322222e-6
GO:0006281 DNA repair 1.337128e-6
GO:0032606 type I interferon production 1.707291e-6
GO:0046985 positive regulation of hemoglobin biosynthetic process 2.071189e-6
GO:0043973 histone H3-K4 acetylation 2.071189e-6
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 2.071189e-6
GO:2000195 negative regulation of female gonad development 2.162919e-6
GO:0035601 protein deacylation 2.535020e-6
GO:0090199 regulation of release of cytochrome c from mitochondria 3.272323e-6
GO:0010821 regulation of mitochondrion organization 3.806446e-6
GO:0016575 histone deacetylation 3.834752e-6
GO:0006476 protein deacetylation 4.784897e-6
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 4.789367e-6
GO:0035691 macrophage migration inhibitory factor signaling pathway 4.789367e-6
GO:0051103 DNA ligation involved in DNA repair 5.604897e-6
GO:0009972 cytidine deamination 7.292511e-6
GO:0031442 positive regulation of mRNA 3'-end processing 7.445129e-6
GO:0032648 regulation of interferon-beta production 8.121634e-6
GO:0045091 regulation of retroviral genome replication 8.371647e-6
GO:0002077 acrosome matrix dispersal 8.629743e-6
GO:0050689 negative regulation of defense response to virus by host 9.089526e-6
GO:0006284 base-excision repair 1.088324e-5
GO:0010741 negative regulation of intracellular protein kinase cascade 1.182518e-5
GO:0032922 circadian regulation of gene expression 1.250495e-5
GO:0010830 regulation of myotube differentiation 1.455897e-5
GO:0060837 blood vessel endothelial cell differentiation 1.491049e-5
GO:0010501 RNA secondary structure unwinding 1.516644e-5
GO:0002604 regulation of dendritic cell antigen processing and presentation 1.631503e-5
GO:0090022 regulation of neutrophil chemotaxis 1.686879e-5
GO:0045358 negative regulation of interferon-beta biosynthetic process 2.136056e-5
GO:0031440 regulation of mRNA 3'-end processing 2.366377e-5
GO:0015936 coenzyme A metabolic process 2.675756e-5
GO:0006266 DNA ligation 3.453610e-5
GO:0043403 skeletal muscle tissue regeneration 3.521781e-5
GO:0035623 renal glucose absorption 3.538195e-5
GO:0035621 ER to Golgi ceramide transport 3.538195e-5
GO:0043300 regulation of leukocyte degranulation 4.245414e-5
GO:0032536 regulation of cell projection size 4.358902e-5
GO:0060932 His-Purkinje system cell differentiation 4.431206e-5
GO:0060926 pacemaker cell development 4.431206e-5
GO:0042107 cytokine metabolic process 4.836027e-5
GO:0032728 positive regulation of interferon-beta production 6.065715e-5
GO:0048002 antigen processing and presentation of peptide antigen 6.712011e-5
GO:0060674 placenta blood vessel development 7.138893e-5
GO:0006783 heme biosynthetic process 7.249936e-5
GO:0003254 regulation of membrane depolarization 7.261030e-5
GO:0009119 ribonucleoside metabolic process 7.406410e-5
GO:0006914 autophagy 7.501867e-5
GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 7.702906e-5
GO:0070383 DNA cytosine deamination 9.631958e-5
GO:0010529 negative regulation of transposition 9.631958e-5
GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly 9.693221e-5
GO:0042454 ribonucleoside catabolic process 9.752850e-5
GO:0046068 cGMP metabolic process 1.017607e-4
GO:0072125 negative regulation of glomerular mesangial cell proliferation 1.021835e-4
GO:0045819 positive regulation of glycogen catabolic process 1.022313e-4
GO:0010989 negative regulation of low-density lipoprotein particle clearance 1.022313e-4
GO:0032836 glomerular basement membrane development 1.030129e-4
GO:0006102 isocitrate metabolic process 1.030129e-4
GO:0014894 response to denervation involved in regulation of muscle adaptation 1.030129e-4
GO:0002579 positive regulation of antigen processing and presentation 1.041665e-4
GO:0016557 peroxisome membrane biogenesis 1.061880e-4
GO:0042089 cytokine biosynthetic process 1.068576e-4
GO:0032425 positive regulation of mismatch repair 1.162544e-4
GO:0060911 cardiac cell fate commitment 1.297484e-4
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1.302037e-4
GO:0015684 ferrous iron transport 1.320903e-4
GO:0007492 endoderm development 1.344791e-4
GO:0060929 atrioventricular node cell fate commitment 1.387140e-4
GO:0060928 atrioventricular node cell development 1.387140e-4
GO:0003342 proepicardium development 1.387140e-4
GO:0003168 cardiac Purkinje fiber cell differentiation 1.387140e-4
GO:0046849 bone remodeling 1.433978e-4
GO:0048742 regulation of skeletal muscle fiber development 1.486480e-4
GO:0090209 negative regulation of triglyceride metabolic process 1.524897e-4
GO:0032094 response to food 1.589380e-4
GO:0007029 endoplasmic reticulum organization 1.703298e-4
GO:0007405 neuroblast proliferation 1.770291e-4
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 2.005912e-4
GO:0045401 positive regulation of interleukin-3 biosynthetic process 2.005912e-4
GO:0007126 meiosis 2.023846e-4
GO:0043409 negative regulation of MAPKKK cascade 2.048467e-4
GO:0006488 dolichol-linked oligosaccharide biosynthetic process 2.162703e-4
GO:0003278 apoptosis involved in heart morphogenesis 2.162703e-4
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 2.263063e-4
GO:0006288 base-excision repair, DNA ligation 2.358622e-4
GO:0070293 renal absorption 2.371456e-4
GO:0060371 regulation of atrial cardiomyocyte membrane depolarization 2.469214e-4
GO:2000142 regulation of transcription initiation, DNA-dependent 2.524622e-4
GO:0046135 pyrimidine nucleoside catabolic process 2.556029e-4
GO:0032835 glomerulus development 2.614226e-4
GO:0090310 negative regulation of methylation-dependent chromatin silencing 2.650403e-4
GO:0031327 negative regulation of cellular biosynthetic process 2.652110e-4
GO:0009948 anterior/posterior axis specification 2.893101e-4
GO:0072015 glomerular visceral epithelial cell development 2.926368e-4
GO:0031129 inductive cell-cell signaling 2.999809e-4
GO:0051321 meiotic cell cycle 3.248927e-4
GO:0043304 regulation of mast cell degranulation 3.407555e-4
GO:0060920 pacemaker cell differentiation 3.492044e-4
GO:0045338 farnesyl diphosphate metabolic process 3.499627e-4
GO:0010906 regulation of glucose metabolic process 3.565747e-4
GO:0031133 regulation of axon diameter 3.587859e-4
GO:0061014 positive regulation of mRNA catabolic process 3.617076e-4
GO:0007252 I-kappaB phosphorylation 3.617076e-4
GO:0006750 glutathione biosynthetic process 3.650353e-4
GO:0032479 regulation of type I interferon production 3.733437e-4
GO:0070374 positive regulation of ERK1 and ERK2 cascade 3.765954e-4
GO:0030002 cellular anion homeostasis 3.841311e-4
GO:0034349 glial cell apoptosis 3.856006e-4
GO:0010677 negative regulation of cellular carbohydrate metabolic process 3.905823e-4
GO:0006342 chromatin silencing 3.933515e-4
GO:0033006 regulation of mast cell activation involved in immune response 4.085309e-4
GO:0051084 'de novo' posttranslational protein folding 4.223323e-4
GO:0046128 purine ribonucleoside metabolic process 4.332313e-4
GO:0070634 transepithelial ammonium transport 4.354888e-4
GO:0045368 positive regulation of interleukin-13 biosynthetic process 4.354888e-4
GO:0042168 heme metabolic process 4.388879e-4
GO:0035518 histone H2A monoubiquitination 4.553156e-4
GO:0003166 bundle of His development 4.602395e-4
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 4.613996e-4
GO:0090138 regulation of actin cytoskeleton organization by cell-cell adhesion 4.613996e-4
GO:0045362 positive regulation of interleukin-1 biosynthetic process 4.613996e-4
GO:0032707 negative regulation of interleukin-23 production 4.613996e-4
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 4.613996e-4
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 4.635346e-4
GO:0060621 negative regulation of cholesterol import 4.635346e-4
GO:2000381 negative regulation of mesoderm development 4.644374e-4
GO:0046984 regulation of hemoglobin biosynthetic process 4.644374e-4
GO:0048286 lung alveolus development 4.676211e-4
GO:0010656 negative regulation of muscle cell apoptosis 4.859547e-4
GO:0045892 negative regulation of transcription, DNA-dependent 4.971982e-4
GO:0072112 glomerular visceral epithelial cell differentiation 4.987024e-4
GO:0046967 cytosol to ER transport 5.071310e-4
GO:0019060 intracellular transport of viral proteins in host cell 5.071310e-4
GO:0010045 response to nickel ion 5.071310e-4
GO:0010918 positive regulation of mitochondrial membrane potential 5.071310e-4
GO:0043653 mitochondrial fragmentation involved in apoptosis 5.082821e-4
GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 5.143045e-4
GO:0015937 coenzyme A biosynthetic process 5.205554e-4
GO:0072166 posterior mesonephric tubule development 5.338682e-4
GO:0030104 water homeostasis 5.353092e-4
GO:0032743 positive regulation of interleukin-2 production 5.360386e-4
GO:0046323 glucose import 5.422232e-4
GO:0030202 heparin metabolic process 5.422232e-4
GO:2000426 negative regulation of apoptotic cell clearance 5.441535e-4
GO:0032916 positive regulation of transforming growth factor beta3 production 5.441535e-4
GO:0090023 positive regulation of neutrophil chemotaxis 5.482112e-4
GO:0006974 response to DNA damage stimulus 5.645709e-4
GO:0048641 regulation of skeletal muscle tissue development 5.833709e-4
GO:0043114 regulation of vascular permeability 5.967078e-4
GO:0072376 protein activation cascade 6.022778e-4
GO:0002577 regulation of antigen processing and presentation 6.061023e-4
GO:0034392 negative regulation of smooth muscle cell apoptosis 6.301013e-4
GO:0033522 histone H2A ubiquitination 6.308652e-4
GO:2000242 negative regulation of reproductive process 6.452175e-4
GO:0060971 embryonic heart tube left/right pattern formation 6.789679e-4
GO:0006507 GPI anchor release 6.789679e-4
GO:0034375 high-density lipoprotein particle remodeling 7.115828e-4
GO:2001022 positive regulation of response to DNA damage stimulus 7.285275e-4
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 7.540370e-4
GO:0009890 negative regulation of biosynthetic process 7.577810e-4
GO:0009615 response to virus 7.685973e-4
GO:0070932 histone H3 deacetylation 7.774381e-4
GO:0071276 cellular response to cadmium ion 8.031484e-4
GO:0031935 regulation of chromatin silencing 8.224503e-4
GO:0060052 neurofilament cytoskeleton organization 8.686618e-4
GO:0002886 regulation of myeloid leukocyte mediated immunity 8.779717e-4
GO:0015696 ammonium transport 8.839412e-4
GO:0010623 developmental programmed cell death 9.026289e-4
GO:0072592 oxygen metabolic process 9.116137e-4
GO:2001021 negative regulation of response to DNA damage stimulus 9.606289e-4
GO:0045579 positive regulation of B cell differentiation 1.004159e-3
GO:0006109 regulation of carbohydrate metabolic process 1.005435e-3
GO:0045921 positive regulation of exocytosis 1.010377e-3
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 1.015025e-3
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 1.080340e-3
GO:2001076 positive regulation of metanephric ureteric bud development 1.082085e-3
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 1.082085e-3
GO:0007356 thorax and anterior abdomen determination 1.082085e-3
GO:0021587 cerebellum morphogenesis 1.090086e-3
GO:0060613 fat pad development 1.090295e-3
GO:0010675 regulation of cellular carbohydrate metabolic process 1.097779e-3
GO:0051153 regulation of striated muscle cell differentiation 1.134039e-3
GO:0021697 cerebellar cortex formation 1.139432e-3
GO:0043306 positive regulation of mast cell degranulation 1.152311e-3
GO:0051253 negative regulation of RNA metabolic process 1.158023e-3
GO:0010629 negative regulation of gene expression 1.186555e-3
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 1.191868e-3
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.202760e-3
GO:2000648 positive regulation of stem cell proliferation 1.214328e-3
GO:0010558 negative regulation of macromolecule biosynthetic process 1.239261e-3
GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining 1.252629e-3
GO:2001038 regulation of cellular response to drug 1.252629e-3
GO:2000685 positive regulation of cellular response to X-ray 1.252629e-3
GO:0035988 chondrocyte proliferation 1.252629e-3
GO:0031052 chromosome breakage 1.252629e-3
GO:0035978 histone H2A-S139 phosphorylation 1.252629e-3
GO:0003131 mesodermal-endodermal cell signaling 1.252629e-3
GO:0030071 regulation of mitotic metaphase/anaphase transition 1.255133e-3
GO:0006366 transcription from RNA polymerase II promoter 1.272870e-3
GO:0010941 regulation of cell death 1.322702e-3
GO:0033005 positive regulation of mast cell activation 1.344192e-3
GO:0009164 nucleoside catabolic process 1.344192e-3
GO:0009116 nucleoside metabolic process 1.363140e-3
GO:0051126 negative regulation of actin nucleation 1.374580e-3
GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly 1.374580e-3
GO:0015693 magnesium ion transport 1.413395e-3
GO:0007354 zygotic determination of anterior/posterior axis, embryo 1.431662e-3
GO:0055085 transmembrane transport 1.438694e-3
GO:0006357 regulation of transcription from RNA polymerase II promoter 1.483854e-3
GO:0010799 regulation of peptidyl-threonine phosphorylation 1.503468e-3
GO:0045357 regulation of interferon-beta biosynthetic process 1.543744e-3
GO:0043302 positive regulation of leukocyte degranulation 1.574161e-3
GO:0048712 negative regulation of astrocyte differentiation 1.593047e-3
GO:0060969 negative regulation of gene silencing 1.624873e-3
GO:0060620 regulation of cholesterol import 1.624873e-3
GO:0045820 negative regulation of glycolysis 1.653149e-3
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1.675042e-3
GO:0045542 positive regulation of cholesterol biosynthetic process 1.749261e-3
GO:0031936 negative regulation of chromatin silencing 1.784062e-3
GO:0070372 regulation of ERK1 and ERK2 cascade 1.804746e-3
GO:0010159 specification of organ position 1.815442e-3
GO:0001869 negative regulation of complement activation, lectin pathway 1.832104e-3
GO:2000020 positive regulation of male gonad development 1.834943e-3
GO:0061013 regulation of mRNA catabolic process 1.848351e-3
GO:0070086 ubiquitin-dependent endocytosis 1.850981e-3
GO:0046638 positive regulation of alpha-beta T cell differentiation 1.864488e-3
GO:0030513 positive regulation of BMP signaling pathway 1.909471e-3
GO:0046928 regulation of neurotransmitter secretion 1.921620e-3
GO:0006888 ER to Golgi vesicle-mediated transport 1.928535e-3
GO:0046855 inositol phosphate dephosphorylation 1.941749e-3
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 1.941749e-3
GO:0070874 negative regulation of glycogen metabolic process 2.001763e-3
GO:0002702 positive regulation of production of molecular mediator of immune response 2.011397e-3
GO:0006956 complement activation 2.044233e-3
GO:0006360 transcription from RNA polymerase I promoter 2.059819e-3
GO:0030573 bile acid catabolic process 2.061438e-3
GO:0008616 queuosine biosynthetic process 2.061438e-3
GO:0019882 antigen processing and presentation 2.081732e-3
GO:0017157 regulation of exocytosis 2.097528e-3
GO:0032663 regulation of interleukin-2 production 2.131645e-3
GO:0051932 synaptic transmission, GABAergic 2.144317e-3
GO:0006683 galactosylceramide catabolic process 2.144317e-3
GO:0021933 radial glia guided migration of cerebellar granule cell 2.144317e-3
GO:0032321 positive regulation of Rho GTPase activity 2.155255e-3
GO:0005981 regulation of glycogen catabolic process 2.257548e-3
GO:0014874 response to stimulus involved in regulation of muscle adaptation 2.265712e-3
GO:0035573 N-terminal peptidyl-serine trimethylation 2.272009e-3
GO:0035572 N-terminal peptidyl-serine dimethylation 2.272009e-3
GO:0072428 signal transduction involved in intra-S DNA damage checkpoint 2.272009e-3
GO:0019086 late viral mRNA transcription 2.272009e-3
GO:0018012 N-terminal peptidyl-alanine trimethylation 2.272009e-3
GO:0018016 N-terminal peptidyl-proline dimethylation 2.272009e-3
GO:0048009 insulin-like growth factor receptor signaling pathway 2.317870e-3
GO:0048041 focal adhesion assembly 2.336756e-3
GO:0006642 triglyceride mobilization 2.336756e-3
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 2.344904e-3
GO:0070633 transepithelial transport 2.363131e-3
GO:0070227 lymphocyte apoptosis 2.364439e-3
GO:0042246 tissue regeneration 2.424970e-3
GO:0090130 tissue migration 2.433452e-3
GO:0072362 regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter 2.540276e-3
GO:0044330 canonical Wnt receptor signaling pathway involved in positive regulation of wound healing 2.540276e-3
GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter 2.540276e-3
GO:0044329 canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion 2.540276e-3
GO:0044328 canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration 2.540276e-3
GO:0021575 hindbrain morphogenesis 2.576479e-3
GO:0015695 organic cation transport 2.589812e-3
GO:0032847 regulation of cellular pH reduction 2.592300e-3
GO:0021707 cerebellar granule cell differentiation 2.592300e-3
GO:0001780 neutrophil homeostasis 2.592300e-3
GO:0030644 cellular chloride ion homeostasis 2.593073e-3
GO:0032667 regulation of interleukin-23 production 2.622752e-3
GO:0030219 megakaryocyte differentiation 2.673081e-3
GO:0050918 positive chemotaxis 2.688945e-3
GO:0043011 myeloid dendritic cell differentiation 2.745817e-3
GO:0051147 regulation of muscle cell differentiation 2.751749e-3
GO:0032660 regulation of interleukin-17 production 2.801074e-3
GO:0070935 3'-UTR-mediated mRNA stabilization 2.825090e-3
GO:0051984 positive regulation of chromosome segregation 2.825090e-3
GO:0000105 histidine biosynthetic process 2.825090e-3
GO:0072124 regulation of glomerular mesangial cell proliferation 2.871762e-3
GO:0048050 post-embryonic eye morphogenesis 2.882664e-3
GO:0080135 regulation of cellular response to stress 2.895790e-3
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 2.905747e-3
GO:0002830 positive regulation of type 2 immune response 2.905747e-3
GO:0009125 nucleoside monophosphate catabolic process 2.944311e-3
GO:0070562 regulation of vitamin D receptor signaling pathway 2.973322e-3
GO:0045767 regulation of anti-apoptosis 3.020800e-3
GO:0045839 negative regulation of mitosis 3.031973e-3
GO:0032185 septin cytoskeleton organization 3.076605e-3
GO:0032497 detection of lipopolysaccharide 3.155797e-3
GO:0043116 negative regulation of vascular permeability 3.177767e-3
GO:0070588 calcium ion transmembrane transport 3.211706e-3
GO:0022415 viral reproductive process 3.227056e-3
GO:0051172 negative regulation of nitrogen compound metabolic process 3.274281e-3
GO:0042278 purine nucleoside metabolic process 3.357122e-3
GO:0034220 ion transmembrane transport 3.369687e-3
GO:0046671 negative regulation of retinal cell programmed cell death 3.437793e-3
GO:0010633 negative regulation of epithelial cell migration 3.437793e-3
GO:0006370 mRNA capping 3.437793e-3
GO:0001570 vasculogenesis 3.461904e-3
GO:0003097 renal water transport 3.476085e-3
GO:0043067 regulation of programmed cell death 3.561452e-3
GO:0010660 regulation of muscle cell apoptosis 3.631745e-3
GO:0002720 positive regulation of cytokine production involved in immune response 3.639254e-3
GO:0019748 secondary metabolic process 3.647669e-3
GO:0010632 regulation of epithelial cell migration 3.649585e-3
GO:0090181 regulation of cholesterol metabolic process 3.649784e-3
GO:0021683 cerebellar granular layer morphogenesis 3.653417e-3
GO:0045686 negative regulation of glial cell differentiation 3.703994e-3
GO:0015760 glucose-6-phosphate transport 3.721699e-3
GO:0007264 small GTPase mediated signal transduction 3.747438e-3
GO:0046069 cGMP catabolic process 3.859816e-3
GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway 3.904731e-3
GO:0014904 myotube cell development 3.996883e-3
GO:0043045 DNA methylation involved in embryo development 3.996883e-3
GO:0006188 IMP biosynthetic process 3.996883e-3
GO:0008219 cell death 4.069912e-3
GO:0070977 bone maturation 4.072714e-3
GO:0051898 negative regulation of protein kinase B signaling cascade 4.112453e-3
GO:0016090 prenol metabolic process 4.150018e-3
GO:0042440 pigment metabolic process 4.250005e-3
GO:0072488 ammonium transmembrane transport 4.251993e-3
GO:0043467 regulation of generation of precursor metabolites and energy 4.333018e-3
GO:0030325 adrenal gland development 4.354005e-3
GO:0030320 cellular monovalent inorganic anion homeostasis 4.367395e-3
GO:0046502 uroporphyrinogen III metabolic process 4.372521e-3
GO:0015734 taurine transport 4.372521e-3
GO:0046148 pigment biosynthetic process 4.379163e-3
GO:0033151 V(D)J recombination 4.379163e-3
GO:0010760 negative regulation of macrophage chemotaxis 4.538680e-3
GO:0001787 natural killer cell proliferation 4.538680e-3
GO:0071545 inositol phosphate catabolic process 4.538749e-3
GO:0006189 'de novo' IMP biosynthetic process 4.568094e-3
GO:0046831 regulation of RNA export from nucleus 4.568094e-3
GO:0045046 protein import into peroxisome membrane 4.572935e-3
GO:0031848 protection from non-homologous end joining at telomere 4.572935e-3
GO:0016559 peroxisome fission 4.572935e-3
GO:0006119 oxidative phosphorylation 4.594029e-3
GO:0002483 antigen processing and presentation of endogenous peptide antigen 4.647377e-3
GO:0006699 bile acid biosynthetic process 4.663345e-3
GO:0014916 regulation of lung blood pressure 4.679285e-3
GO:0072091 regulation of stem cell proliferation 4.734113e-3
GO:0048332 mesoderm morphogenesis 4.902201e-3
GO:0006703 estrogen biosynthetic process 4.943063e-3
GO:0046579 positive regulation of Ras protein signal transduction 4.945607e-3
GO:0030502 negative regulation of bone mineralization 5.043452e-3
GO:0060931 sinoatrial node cell development 5.070197e-3
GO:0003167 atrioventricular bundle cell differentiation 5.070197e-3
GO:0045738 negative regulation of DNA repair 5.126413e-3
GO:0050687 negative regulation of defense response to virus 5.240932e-3
GO:0042981 regulation of apoptosis 5.244124e-3
GO:0070302 regulation of stress-activated protein kinase signaling cascade 5.247704e-3
GO:0006310 DNA recombination 5.315907e-3
GO:0060038 cardiac muscle cell proliferation 5.371719e-3
GO:0032757 positive regulation of interleukin-8 production 5.535283e-3
GO:0034983 peptidyl-lysine deacetylation 5.583936e-3
GO:0016998 cell wall macromolecule catabolic process 5.596976e-3
GO:0030225 macrophage differentiation 5.636223e-3
GO:0070295 renal water absorption 5.641821e-3
GO:0034369 plasma lipoprotein particle remodeling 5.672060e-3
GO:0045087 innate immune response 5.806254e-3
GO:0060319 primitive erythrocyte differentiation 5.877149e-3
GO:0055117 regulation of cardiac muscle contraction 5.953644e-3
GO:0046329 negative regulation of JNK cascade 5.966583e-3
GO:0050916 sensory perception of sweet taste 6.015402e-3
GO:0006713 glucocorticoid catabolic process 6.015402e-3
GO:0000917 barrier septum formation 6.015402e-3
GO:0055009 atrial cardiac muscle tissue morphogenesis 6.025560e-3
GO:0035802 adrenal cortex formation 6.036536e-3
GO:0010350 cellular response to magnesium starvation 6.036536e-3
GO:0046483 heterocycle metabolic process 6.050061e-3
GO:0060442 branching involved in prostate gland morphogenesis 6.167327e-3
GO:0071577 zinc ion transmembrane transport 6.199133e-3
GO:0018108 peptidyl-tyrosine phosphorylation 6.251372e-3
GO:0060741 prostate gland stromal morphogenesis 6.262691e-3
GO:0021578 hindbrain maturation 6.262691e-3
GO:0048755 branching morphogenesis of a nerve 6.262691e-3
GO:0006784 heme a biosynthetic process 6.460239e-3
GO:0048619 embryonic hindgut morphogenesis 6.485240e-3
GO:2000781 positive regulation of double-strand break repair 6.535081e-3
GO:0060381 positive regulation of single-stranded telomeric DNA binding 6.535081e-3
GO:0009786 regulation of asymmetric cell division 6.535081e-3
GO:0031468 nuclear envelope reassembly 6.535081e-3
GO:0006924 activation-induced cell death of T cells 6.558216e-3
GO:0006264 mitochondrial DNA replication 6.589300e-3
GO:0035234 germ cell programmed cell death 6.589300e-3
GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade 6.660501e-3
GO:0055086 nucleobase-containing small molecule metabolic process 6.700668e-3
GO:0051085 chaperone mediated protein folding requiring cofactor 6.705873e-3
GO:0045453 bone resorption 6.754588e-3
GO:0001894 tissue homeostasis 6.794715e-3
GO:0007498 mesoderm development 6.814227e-3
GO:0051973 positive regulation of telomerase activity 6.818321e-3
GO:0016265 death 6.834573e-3
GO:2000018 regulation of male gonad development 6.869101e-3
GO:0009404 toxin metabolic process 6.869101e-3
GO:0070168 negative regulation of biomineral tissue development 6.902216e-3
GO:0008595 anterior/posterior axis specification, embryo 6.915127e-3
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 6.930515e-3
GO:0044272 sulfur compound biosynthetic process 6.968838e-3
GO:0046487 glyoxylate metabolic process 7.055358e-3
GO:0019532 oxalate transport 7.055358e-3
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain 7.179040e-3
GO:0043508 negative regulation of JUN kinase activity 7.248645e-3
GO:0070141 response to UV-A 7.336070e-3
GO:0045719 negative regulation of glycogen biosynthetic process 7.336070e-3
GO:0055069 zinc ion homeostasis 7.378267e-3
GO:0007129 synapsis 7.378267e-3
GO:0048102 autophagic cell death 7.379068e-3
GO:0033235 positive regulation of protein sumoylation 7.416076e-3
GO:0070192 chromosome organization involved in meiosis 7.453109e-3
GO:0001516 prostaglandin biosynthetic process 7.453109e-3
GO:0050685 positive regulation of mRNA processing 7.594981e-3
GO:0060463 lung lobe morphogenesis 7.874755e-3
GO:0043088 regulation of Cdc42 GTPase activity 7.874755e-3
GO:0021696 cerebellar cortex morphogenesis 7.960085e-3
GO:0021702 cerebellar Purkinje cell differentiation 7.996299e-3
GO:0046637 regulation of alpha-beta T cell differentiation 8.023655e-3
GO:0016202 regulation of striated muscle tissue development 8.094004e-3
GO:0045404 positive regulation of interleukin-4 biosynthetic process 8.134921e-3
GO:0019048 virus-host interaction 8.193356e-3
GO:0002663 positive regulation of B cell tolerance induction 8.251104e-3
GO:0061198 fungiform papilla formation 8.251104e-3
GO:0006829 zinc ion transport 8.273383e-3
GO:0045109 intermediate filament organization 8.293829e-3
GO:0051057 positive regulation of small GTPase mediated signal transduction 8.351210e-3
GO:0001935 endothelial cell proliferation 8.372342e-3
GO:0001732 formation of translation initiation complex 8.376728e-3
GO:0034330 cell junction organization 8.379414e-3
GO:0015012 heparan sulfate proteoglycan biosynthetic process 8.386851e-3
GO:0043931 ossification involved in bone maturation 8.457229e-3
GO:0006044 N-acetylglucosamine metabolic process 8.501323e-3
GO:0030500 regulation of bone mineralization 8.529842e-3
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 8.628947e-3
GO:0006198 cAMP catabolic process 8.704832e-3
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 8.705182e-3
GO:0055017 cardiac muscle tissue growth 8.732483e-3
GO:0034655 nucleobase-containing compound catabolic process 8.738963e-3
GO:0046668 regulation of retinal cell programmed cell death 8.814924e-3
GO:0014047 glutamate secretion 8.814924e-3
GO:0071624 positive regulation of granulocyte chemotaxis 8.875989e-3
GO:0070535 histone H2A K63-linked ubiquitination 8.875989e-3
GO:0090104 pancreatic E cell differentiation 8.875989e-3
GO:0031860 telomeric 3' overhang formation 8.875989e-3
GO:0003311 pancreatic D cell differentiation 8.875989e-3
GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore 8.875989e-3
GO:0010463 mesenchymal cell proliferation 9.007656e-3
GO:2001020 regulation of response to DNA damage stimulus 9.180303e-3
GO:0006705 mineralocorticoid biosynthetic process 9.208378e-3
GO:0048210 Golgi vesicle fusion to target membrane 9.284829e-3
GO:0032784 regulation of transcription elongation, DNA-dependent 9.323182e-3
GO:0006882 cellular zinc ion homeostasis 9.323182e-3
GO:2000425 regulation of apoptotic cell clearance 9.521716e-3
GO:0043691 reverse cholesterol transport 9.553040e-3
GO:0032026 response to magnesium ion 9.590503e-3
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 9.590503e-3
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 9.707260e-3
GO:0043154 negative regulation of caspase activity 9.719619e-3
GO:0046666 retinal cell programmed cell death 9.839391e-3
GO:0035584 calcium-mediated signaling using intracellular calcium source 9.839391e-3
GO:0022616 DNA strand elongation 9.839391e-3
GO:0035356 cellular triglyceride homeostasis 9.965229e-3
GO:0019464 glycine decarboxylation via glycine cleavage system 9.965229e-3
GO:0060699 regulation of endoribonuclease activity 9.965229e-3
GO:0000055 ribosomal large subunit export from nucleus 9.965229e-3
GO:0000056 ribosomal small subunit export from nucleus 9.965229e-3
GO:0006348 chromatin silencing at telomere 9.965229e-3
GO:0045104 intermediate filament cytoskeleton organization 9.970450e-3
GO:0045815 positive regulation of gene expression, epigenetic 9.973742e-3
GO:0050778 positive regulation of immune response 1.016734e-2
GO:0007008 outer mitochondrial membrane organization 1.021791e-2
GO:0008633 activation of pro-apoptotic gene products 1.024693e-2
GO:0035404 histone-serine phosphorylation 1.045547e-2
GO:0032873 negative regulation of stress-activated MAPK cascade 1.045547e-2
GO:0061370 testosterone biosynthetic process 1.047157e-2
GO:0009648 photoperiodism 1.047157e-2
GO:0006942 regulation of striated muscle contraction 1.048092e-2
GO:0042074 cell migration involved in gastrulation 1.049682e-2
GO:0051279 regulation of release of sequestered calcium ion into cytosol 1.054955e-2
GO:0045071 negative regulation of viral genome replication 1.056481e-2
GO:0061044 negative regulation of vascular wound healing 1.062836e-2
GO:2000098 negative regulation of smooth muscle cell-matrix adhesion 1.062836e-2
GO:0071258 cellular response to gravity 1.062836e-2